The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi最新文献_第8页

Leucovorin-induced Hypersensitivity Reaction in a Patient with Metastatic Colorectal Cancer Treated with Cetuximab Plus FOLFOX Chemotherapy: A Case Report. 一名接受西妥昔单抗加 FOLFOX 化疗的转移性结直肠癌患者的亮菌甲素诱发高敏反应：病例报告。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-12-25 DOI: 10.4166/kjg.2023.114

Minna Kim, Dong Hyun Kim, Jong Yoon Lee, Young-Hee Nam, Jong Hoon Lee

{"title":"Leucovorin-induced Hypersensitivity Reaction in a Patient with Metastatic Colorectal Cancer Treated with Cetuximab Plus FOLFOX Chemotherapy: A Case Report.","authors":"Minna Kim, Dong Hyun Kim, Jong Yoon Lee, Young-Hee Nam, Jong Hoon Lee","doi":"10.4166/kjg.2023.114","DOIUrl":"10.4166/kjg.2023.114","url":null,"abstract":"The FOLFOX regimen (combination of leucovorin, 5-fluorouracil, and oxaliplatin) is the first-line treatment for high-risk stage 2 and 3 colorectal cancer patients. While hypersensitivity reactions (HSRs) caused by oxaliplatin are commonly reported, HSRs due to leucovorin have been infrequently reported. This report aims to investigate the clinical presentation, diagnosis, and management of leucovorin induced HSRs. A 60-year-old female developed generalized edema, dyspnea, and facial redness during cetuximab plus FOLFOX chemotherapy administered for management of metastatic colorectal cancer. Because HSRs induced by oxaliplatin are commonly reported, we initially presumed an oxaliplatin-induced HSR. However, despite undergoing oxaliplatin desensitization, HSRs persisted, and they were still observed when leucovorin was administered without oxaliplatin. The patient was diagnosed with leucovorin-induced HSR and underwent leucovorin desensitization. However, the reactions recurred within 30 minutes of the initiating the desensitization. Considering unsuccessful leucovorin desensitization, leucovorin was excluded. The patient received cetuximab and oxaliplatin chemotherapy without leucovorin to date without any adverse effects. While leucovorin-induced HSRs are infrequently reported, they should still be regarded as potential adverse effects.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 6","pages":"288-294"},"PeriodicalIF":0.0,"publicationDate":"2023-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Small Bowel Variceal Bleeding in Patients with Liver Cirrhosis Treated with Transarterial Embolization: Case Series. 经动脉栓塞治疗肝硬化患者的小肠静脉曲张出血：病例系列。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-12-25 DOI: 10.4166/kjg.2023.116

Boram Seo, Ju Ho Lee, Eun Jeong Jang, Sang Woon Park, Ju Sang Park, Sang Jong Park, Sang-Jung Kim, Jae Woo Yeon, Ah Young Lee, Jun-Young Seo

引用次数: 0

Association Preoperative Protein Adequacy and Post Elective Laparotomy Surgical Site Infection. 术前蛋白质充足度与择期腹腔手术后手术部位感染的关系

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-12-25 DOI: 10.4166/kjg.2023.103

Davie Muhamad, Nurul Ratna Mutu Manikam, Ridho Ardhi Syaiful

{"title":"Association Preoperative Protein Adequacy and Post Elective Laparotomy Surgical Site Infection.","authors":"Davie Muhamad, Nurul Ratna Mutu Manikam, Ridho Ardhi Syaiful","doi":"10.4166/kjg.2023.103","DOIUrl":"10.4166/kjg.2023.103","url":null,"abstract":"Background/aims: Postoperative complications tend to occur in high-risk populations, including those undergoing major surgery. Surgical site infections (SSI) are some of the most common postoperative complications in laparotomy procedures. Surgery induces a postoperative stress response, triggering an inflammatory process that increases muscle protein proteolysis. Preoperative protein intake increases muscle protein reserves and supports postoperative wound healing and immunity. This study analyzed the association between preoperative protein adequacy and post-elective laparotomy SSI.Methods: A prospective cohort study was conducted on 93 subjects with an adequate protein group of 48 subjects and an inadequate protein group of 45 subjects undergoing elective laparotomy at Dr. Cipto Mangunkusumo Hospital, Jakarta. The protein adequacy was analyzed using an interview method for seven days preoperatively. Patient monitoring was carried out for 30 days postoperatively to assess the complications in the form of SSIs. The association between protein adequacy and SSI was analyzed using a Chi-Square test, and multivariate analysis was performed to assess the factors most associated with post-elective laparotomy SSI.Results: An association was observed between preoperative protein adequacy and post-elective laparotomy SSI (RR 3.413; 95% CI, 1.363-8.549; p=0.004). Multivariate analysis showed that the preoperative protein adequacy and preoperative albumin levels were strongly predictive of the occurrence of SSI.Conclusions: The preoperative protein adequacy and albumin levels were strongly related to predicting the post-elective laparotomy SSI.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 6","pages":"282-287"},"PeriodicalIF":0.0,"publicationDate":"2023-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of Severe Colon Stricture after Rituximab Therapy for Concomitant Mucosa-associated Lymphoid Tissue Lymphoma in a Patient with Ulcerative Colitis. 利妥昔单抗治疗溃疡性结肠炎患者伴发粘膜相关淋巴组织淋巴瘤后严重结肠狭窄的改善

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-11-25 DOI: 10.4166/kjg.2023.101

Hyun Joon Park, Won Moon, Seun Ja Park, Moo In Park, Sung Eun Kim, Jae Hyun Kim, Kyoungwon Jung, Kwang Il Seo, Eun Mi Lee, Minjung Jung

{"title":"Improvement of Severe Colon Stricture after Rituximab Therapy for Concomitant Mucosa-associated Lymphoid Tissue Lymphoma in a Patient with Ulcerative Colitis.","authors":"Hyun Joon Park, Won Moon, Seun Ja Park, Moo In Park, Sung Eun Kim, Jae Hyun Kim, Kyoungwon Jung, Kwang Il Seo, Eun Mi Lee, Minjung Jung","doi":"10.4166/kjg.2023.101","DOIUrl":"10.4166/kjg.2023.101","url":null,"abstract":"Colorectal strictures are uncommon in patients with ulcerative colitis (UC). An extranodal marginal zone B-cell lymphoma of mucosa- associated lymphoid tissue (MALT) lymphoma is rarely involved in the colon but may be associated with inflammatory bowel diseases. A 41-year-old female with a six-year history of UC presented with a severe stricture of the sigmoid colon that prevented the passage of a colonoscope. A histological examination revealed non-specific inflammation and fibrosis without dysplasia or cancer. Despite conventional treatment, including mesalazine and azathioprine for one year after that visit, the stricture persisted. In addition, diffuse, edematous exudative inflammation and multiple shallow ulcers were observed in the distal rectum, revealing a MALT lymphoma testing positive for CD20, CD43, CD5, and Bcl-2, but negative for CD3, CD10, CD23, and cyclin-D1. Four weekly doses of rituximab were administered. Follow-up colonoscopy performed one month after treatment revealed slight improvement in the rectal lesion without remnant histological evidence of a MALT lymphoma. In addition, the stricture showed marked improvement, and the colonoscope could pass easily through the stricture site. This is the first case report on an improvement of a severe sigmoid colon stricture in a patient with UC after rituximab treatment for a concomitant rectal MALT lymphoma.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 5","pages":"254-260"},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pulmonary Complications in Patients with Liver Cirrhosis]. [肝硬化患者肺部并发症]。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-11-25 DOI: 10.4166/kjg.2023.123

Seul Ki Han, Soon Koo Baik, Moon Young Kim

引用次数: 0

Case of Concomitant Endoscopic Treatment of Achalasia with Superficial Esophageal Cancer. 内镜下治疗贲门失弛缓症合并浅表性食管癌一例。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-11-25 DOI: 10.4166/kjg.2023.099

Myung-Hun Lee, Kyoungwon Jung, Jae Hyun Kim, Sung Eun Kim, Won Moon, Moo In Park, Seun Ja Park

引用次数: 0

[Hemodynamic Changes in Chronic Liver Disease]. 慢性肝病的血流动力学变化。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-11-25 DOI: 10.4166/kjg.2023.124

Sangyong Jo, Kyungil Park

引用次数: 0

Impact of COVID-19 Pandemic on Performance of Gastrointestinal Endoscopy. COVID-19大流行对胃肠内镜检查性能的影响

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-11-25 DOI: 10.4166/kjg.2023.102

Youn Kyung Kim, Su Bee Park, Moonhyung Lee, Jin Young Youn, Min Seob Kwak, Jae Myung Cha

{"title":"Impact of COVID-19 Pandemic on Performance of Gastrointestinal Endoscopy.","authors":"Youn Kyung Kim, Su Bee Park, Moonhyung Lee, Jin Young Youn, Min Seob Kwak, Jae Myung Cha","doi":"10.4166/kjg.2023.102","DOIUrl":"10.4166/kjg.2023.102","url":null,"abstract":"Background/aims: Non-time-sensitive gastrointestinal endoscopy was deferred because of the risk of exposure to coronavirus disease 2019 (COVID-19), but no population-based studies have quantified the adverse impact on gastrointestinal procedures. This study examined the impact of the COVID-19 pandemic on the performance of esophagogastroduodenoscopy (EGD), colonoscopy, ERCP, and abdominal ultrasonography (US) in South Korea.Methods: This nationwide, population-based study compared the claim data of EGD, colonoscopy, ERCP, and abdominal US in 2020 and 2021 (COVID-19 era) with those in 2019 (before the COVID-19 era).Results: During the first year (2020) of the COVID-19 pandemic, the annual claim data of EGD and colonoscopy were reduced by 6.3% and 6.9%, respectively, but those of ERCP and abdominal US were increased by 1.0% and 2.9%, compared to those in 2019. During the first surge (March and April 2020) of COVID-19, the monthly claim data of EGD, colonoscopy, ERCP, and abdominal US were reduced by 28.8%, 43.8%, 5.1%, and 21.6%, respectively, in March 2020, and also reduced by 17.2%, 32.8%, 4.4%, and 9.5%, respectively, in April 2020, compared to those in March and April 2019. During March and April 2020, the monthly claims of ERCP, compared with those in 2019, declined less significantly than those of EGD and colonoscopy (both p<0.001).Conclusions: The claims of EGD and colonoscopy were reduced more significantly than those of ERCP and abdominal US during the COVID-19 pandemic because ERCPs are time-sensitive procedures and abdominal USs are non-aerosolized procedures.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 5","pages":"239-247"},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Hepatorenal Syndrome]. [肝肾综合征]。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-11-25 DOI: 10.4166/kjg.2023.108

Jun Cheol Choi, Jeong-Ju Yoo

{"title":"[Hepatorenal Syndrome].","authors":"Jun Cheol Choi, Jeong-Ju Yoo","doi":"10.4166/kjg.2023.108","DOIUrl":"10.4166/kjg.2023.108","url":null,"abstract":"Hepatorenal syndrome (HRS) is a critical and potentially life-threatening complication of advanced liver disease, including cirrhosis. It is characterized by the development of renal dysfunction in the absence of underlying structural kidney pathology. The pathophysiology of HRS involves complex interactions between systemic and renal hemodynamics, neurohormonal imbalances, and the intricate role of vasoconstrictor substances. Understanding these mechanisms is crucial for the timely identification and management of HRS. The diagnosis of HRS is primarily clinical and relies on specific criteria that consider the exclusion of other causes of renal dysfunction. The management of HRS comprises two main approaches: vasoconstrictor therapy and albumin infusion, which aim to improve renal perfusion and mitigate the hyperdynamic circulation often seen in advanced liver disease. Additionally, strategies such as liver transplantation and renal replacement therapy are essential considerations based on individual patient characteristics and disease severity. This review article provides a comprehensive overview of hepatorenal syndrome, focusing on its pathophysiology, diagnostic criteria, and current management strategies.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"82 5","pages":"224-232"},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Sarcopenia in Chronic Liver Disease]. [慢性肝病中的肌肉减少症]。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2023-11-25 DOI: 10.4166/kjg.2023.127

Kwang Il Seo

引用次数: 0