The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi最新文献

[Upper Gastrointestinal Foreign Body Removal]. [上消化道异物清除术]。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.017

Heung Up Kim

{"title":"[Upper Gastrointestinal Foreign Body Removal].","authors":"Heung Up Kim","doi":"10.4166/kjg.2025.017","DOIUrl":"https://doi.org/10.4166/kjg.2025.017","url":null,"abstract":"Upper gastrointestinal foreign body disease can range from mild to severe, with the esophagus in most danger because it can cause respiratory complications such as choking and lung aspiration. In addition, it is located in the center of the chest, with vital organs such as the aorta, heart, lungs, and vena cava in close proximity. Perforation of the esophagus by a foreign body can cause sepsis with potentially fatal complications such as aorto-esophageal fistula and pneumothorax. Sharp objects, food clumps, and disk batteries are the most common types of foreign bodies that can cause serious complications in the esophagus. The most common sharp foreign body is a fish bone, and complete esophageal obstructions are often caused by meat clumps. Hence, they are the two most common types of foreign bodies and should be treated with emergency care. An aorto-esophageal fistula, the most serious of foreign body complications, can lead to massive bleeding. Therefore, it is important to recognize clinical suspicion and know what to do in an emergency. In foreign body disease, efforts should be made to reduce complications from the foreign body rather than remove the foreign body itself, and clinicians should familiarize themselves with the characteristics of intentional foreign bodies and body packers that have emerged in recent years.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"299-308"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Varied Characteristics of Recovered Patients with Biliary Atresia. 胆道闭锁康复患者的不同特征。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.020

Firyal Nadiah Rahmah, Rendi Aji Prihaningtyas, Bagus Setyoboedi, Sjamsul Arief

{"title":"Varied Characteristics of Recovered Patients with Biliary Atresia.","authors":"Firyal Nadiah Rahmah, Rendi Aji Prihaningtyas, Bagus Setyoboedi, Sjamsul Arief","doi":"10.4166/kjg.2025.020","DOIUrl":"https://doi.org/10.4166/kjg.2025.020","url":null,"abstract":"Background/aims: Biliary atresia (BA) is a progressive cholangiopathy of infancy that leads to cholestasis, bile duct fibrosis, and liver cirrhosis if untreated. This study aimed to evaluate the demographic, clinical, and laboratory characteristics of infants with BA and identify prognostic factors influencing treatment outcomes.Methods: A retrospective observational design was used, analyzing medical records of 152 infants diagnosed with BA over a three-year period. Data included clinical manifestations, laboratory findings, diagnostic procedures, and treatment outcomes. Statistical analyses were conducted to assess factors affecting recovery and survival.Results: The results indicated a mean patient age of 13.9 weeks, with jaundice onset at 3.3 weeks and an average duration of 10.7 weeks. The overall survival rate was 81.6%, while 48% experienced treatment failure. Recovery rates were significantly associated with younger age at diagnosis (p=0.000), shorter jaundice duration (p=0.002), and absence of portal hypertension (p<0.001).Conclusions: These findings highlight the importance of early diagnosis and intervention in improving BA outcomes. Future research should focus on optimizing treatment strategies to enhance long-term survival.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"357-365"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Clinical Significance of the Mean Nocturnal Baseline Impedance and Post-Reflux Swallow-Induced Peristaltic Wave Index in the Diagnosis of Gastroesophageal Reflux Disease]. [平均夜间基线阻抗和反流后吞咽诱发的肠波指数在胃食管反流病诊断中的临床意义]。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.069

Ju Yup Lee

{"title":"[Clinical Significance of the Mean Nocturnal Baseline Impedance and Post-Reflux Swallow-Induced Peristaltic Wave Index in the Diagnosis of Gastroesophageal Reflux Disease].","authors":"Ju Yup Lee","doi":"10.4166/kjg.2025.069","DOIUrl":"https://doi.org/10.4166/kjg.2025.069","url":null,"abstract":"Gastroesophageal reflux disease (GERD) is a common condition characterized by the reflux of gastric contents into the esophagus, often leading to troublesome symptoms or complications. Although the acid exposure time (AET) has long been used as a key diagnostic marker, it may be insufficient in certain clinical situations, particularly in patients with borderline AET. Recently, two novel impedance-based parameters have emerged as useful adjuncts in the diagnostic evaluation of GERD: mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced peristaltic wave index (PSPW-I). These metrics reflect the esophageal mucosal integrity and chemical clearance, offering physiologically relevant insights beyond AET. Studies suggest that a low MNBI (<1,500 Ω) and PSPW-I (<61%) are associated with pathological reflux and favorable response to proton pump inhibitors. Moreover, the combined use of MNBI and PSPW-I may enhance diagnostic accuracy and aid in predicting the therapeutic outcomes. This review summarizes the physiological background, diagnostic thresholds, and clinical implications of MNBI and PSPW-I based on the current literature and highlights their potential role in GERD diagnosis and management. Nevertheless, future standardization and automation may further improve their clinical utility.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"274-279"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Series: Is Celiac Disease Underdiagnosed in Korean Children? 病例系列：韩国儿童乳糜泻诊断不足吗？

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.041

Ji Hyun Moon, Anna Pham-Short, Cheng Hiang Lee, Susan Siew, Nicole Graf, Yoon Hi Cho

引用次数: 0

SPB-201 Alleviates Indomethacin-Induced Gastric Damage in Rats through Its Antioxidant, Anti-inflammatory, and Pro-angiogenic Properties. SPB-201通过其抗氧化、抗炎和促血管生成特性减轻吲哚美辛引起的大鼠胃损伤。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.035

Seonghyun Ho, Seon Hee Kim, Su-Jin Park

{"title":"SPB-201 Alleviates Indomethacin-Induced Gastric Damage in Rats through Its Antioxidant, Anti-inflammatory, and Pro-angiogenic Properties.","authors":"Seonghyun Ho, Seon Hee Kim, Su-Jin Park","doi":"10.4166/kjg.2025.035","DOIUrl":"https://doi.org/10.4166/kjg.2025.035","url":null,"abstract":"Background/aims: The inhibition of prostaglandin (PG) synthesis by indomethacin causes gastric ulceration by inducing oxidative stress and inflammation.Methods: This study investigated the protective effects of an Artemisia annua extract powder (SPB-201) on gastric damage and its underlying mechanisms by analyzing various molecular biological markers in indomethacin-induced gastric ulceration rats and AGS human gastric cancer cells.Results: The oral administration of SPB-201 augmented the gastroprotective PGE2 and NO contents by increasing COX-1, COX-2, and eNOS expression, resulting in the improvement of gastric damage and ulcerative hyperemia in rats. In addition, elevated levels of mucin and pro-angiogenic factors, including EGF, bFGF, VEGF, and TGF-β1, were observed in the gastric tissue of rats treated with SPB-201. Furthermore, SPB-201 induced the SOD and CAT activities in rats but reduced the protein and mRNA levels of TNF-α, IL-1β, and IL-6. In addition, the SPB-201 treatment showed a dose-dependent and statistically significant increase in COX-1, COX-2, and PGE2 production in AGS cells exposed to indomethacin.Conclusions: SPB-201 might be an excellent candidate for developing anti-ulcer agents that prevent or treat gastric injury caused by NSAIDs, through antioxidant, anti-inflammatory, and pro-angiogenic mechanisms.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"366-381"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Expanding Role of Gastroenterologists in Acute Gastrointestinal Graft-versus-Host Disease: From Diagnosis and Management to Microbiome-Based Strategies]. [胃肠病学家在急性胃肠道移植物抗宿主病中的作用：从诊断和管理到基于微生物组的策略]。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.049

Seung Bum Lee

引用次数: 0

Diagnosis and Management of Benign Liver Tumors. 肝脏良性肿瘤的诊断与治疗。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.046

Yeonjung Ha

{"title":"Diagnosis and Management of Benign Liver Tumors.","authors":"Yeonjung Ha","doi":"10.4166/kjg.2025.046","DOIUrl":"https://doi.org/10.4166/kjg.2025.046","url":null,"abstract":"Benign liver tumors include a heterogeneous group of lesions from different cellular origins that are found incidentally. As the name suggests, these lesions have a \"benign\" clinical course. Contrast-enhanced (CE) abdominal imaging is used to differentiate and confirm the diagnosis of these lesions. Benign liver tumors can be classified as 1) epithelial lesions and 2) non-epithelial lesions. Epithelial lesions originating from hepatocytes or cholangiocytes include focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA). Hepatic hemangioma (HH) is a representative example of non-epithelial lesions originating from mesenchymal cells. HH is the most common primary liver tumor, affecting 0.4-20% of the general population. CE imaging reveals a characteristic pattern, with early peripheral nodular enhancement followed by centripetal filling in the delayed phase. FNH is the second most common benign liver tumor. The fibrous tissue within the central scar and radiating septa show distinct persistent enhancement on CE imaging. HCA is relatively rare and significantly associated with the long-term use of oral contraceptive pills, obesity, and metabolic syndrome. Despite its benign nature, spontaneous rupture or malignant transformation can occur. Most benign liver tumors do not require treatment, but oral contraceptive pills should be discontinued in patients with HCA. A surgical resection can be considered in some cases of HCA based on the risk of spontaneous rupture or malignant transformation.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"314-318"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of Pancreatic Cancer in Inflammatory Pancreatic Diseases. 炎症性胰腺疾病中胰腺癌的风险

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.019

J-Matthias Löhr, Miroslav Vujasinovic, Patrick Maisonneuve

引用次数: 0

Cronkhite-Canada Syndrome Presenting as Diarrhea and Weight Loss: A Case Report and Literature Review. cronkite - canada综合征表现为腹泻和体重减轻：1例报告和文献回顾。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.047

Woo Jin Kim, Jin Ook Jang, Cheol Min Lee, Su Bin Synn, Su Bum Park

{"title":"Cronkhite-Canada Syndrome Presenting as Diarrhea and Weight Loss: A Case Report and Literature Review.","authors":"Woo Jin Kim, Jin Ook Jang, Cheol Min Lee, Su Bin Synn, Su Bum Park","doi":"10.4166/kjg.2025.047","DOIUrl":"https://doi.org/10.4166/kjg.2025.047","url":null,"abstract":"Cronkhite-Canada syndrome (CCS) is a rare, non-hereditary disorder characterized by diffuse, non-neoplastic gastrointestinal polyposis along with ectodermal abnormalities, such as alopecia, skin hyperpigmentation, and nail dystrophy. It typically affects individuals aged >50 years and can lead to severe complications, including protein-losing enteropathy, chronic diarrhea, and malnutrition, if not diagnosed early. We report the case of a 68-year-old male who presented with a 2-month history of diarrhea, weight loss, and hair loss. Endoscopic and histopathological examinations revealed diffuse polyposis throughout the gastrointestinal tract, consistent with CCS findings. The patient was treated with a combination of corticosteroids and azathioprine, which led to marked clinical and endoscopic improvements. No recurrence was observed during 1 year of follow-up period. This case highlights the importance of recognizing the typical clinical and diagnostic features of CCS. Owing to its nonspecific presentation, diagnosis may be delayed, potentially worsening the prognosis. Therefore, CCS should be considered in the differential diagnosis of middle-aged or older patients who present with multiple gastrointestinal polyps accompanied by ectodermal symptoms. Early recognition and appropriate immunosuppressive therapy are essential for improving patient outcomes and preventing complications. Long-term surveillance is necessary because of the potential for polyp recurrence or malignant transformation.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"413-420"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case of Hepatic Angiomyolipoma: An Unusual Hepatic Lesion with a Review of Diagnostic and Management Challenges. 1例肝血管平滑肌脂肪瘤：一种罕见的肝脏病变，诊断和治疗方面的挑战。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.036

Bushra Kurban, Deepti Shukla, Shamas Zaman, Muhannad Al Okla

引用次数: 0