The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi最新文献_第2页

Emerging Therapeutics for Primary Biliary Cholangitis. 原发性胆道胆管炎的新疗法。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.045

Eun Ju Cho

引用次数: 0

Self-Reported Food Triggers and Food Fears Impact Nutrient Intake and Quality of Life in Patients with Irritable Bowel Syndrome and Functional Dyspepsia. 自我报告的食物触发因素和食物恐惧影响肠易激综合征和功能性消化不良患者的营养摄入和生活质量

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.039

Omesh Goyal, Manjeet Kumar Goyal, Abhinav Gupta, Shaveta Batta, Arshdeep Singh, Prerna Goyal, Varun Mehta, Ajit Sood

{"title":"Self-Reported Food Triggers and Food Fears Impact Nutrient Intake and Quality of Life in Patients with Irritable Bowel Syndrome and Functional Dyspepsia.","authors":"Omesh Goyal, Manjeet Kumar Goyal, Abhinav Gupta, Shaveta Batta, Arshdeep Singh, Prerna Goyal, Varun Mehta, Ajit Sood","doi":"10.4166/kjg.2025.039","DOIUrl":"https://doi.org/10.4166/kjg.2025.039","url":null,"abstract":"Background/aims: Self-reported food triggers are common in patients with irritable bowel syndrome (IBS) and functional dyspepsia (FD), often leading to dietary restrictions which can be exacerbated by \"fear of food.\" This study aimed to evaluate the frequency of self-reported food triggers and food-related fears in IBS and FD patients and assess their impact on nutrient intake and health-related quality of life (HRQoL).Methods: Patients meeting Rome IV criteria for IBS or FD, along with healthy controls (HCs), were enrolled. Dietary intake was assessed using a validated questionnaire; food-related fear using the 'Fear of Food Questionnaire-18', and HRQoL using the PROMIS Global-10 tool.Results: Total 811 participants (FD: 244, IBS: 160, HCs: 407; mean age: 42.3±12.3 years; males: 58.5%) were included. IBS and FD patients reported significantly more food triggers than HCs, the most frequent being spicy/fried foods in FD (50.4%) and constipation-predominant IBS (39.7%), and milk in diarrhoea-predominant IBS (70.1%). Total intake of energy, protein, fat, carbohydrates, and FODMAPs was significantly lower in IBS and FD patients compared to HCs. Food-related fear scores were significantly higher in IBS and FD patients and showed a strong correlation with both the number of food triggers and reduced nutrient intake. Food triggers negatively impacted HRQoL, both directly and indirectly, through food-related fear.Conclusions: Patients with IBS and FD report significantly more food triggers which correlates with reduced macronutrient and FODMAP intake. Food-related fear is strongly associated with diminished nutrient consumption and lower HRQoL. These findings highlight the importance of personalized psychological and dietary interventions in management of IBS and FD.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"345-356"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Seoul Consensus on Clinical Practice Guidelines for Functional Constipation]. [功能性便秘临床实践指南首尔共识]。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2024.156

Kyung Ho Song, Young Sin Cho, Jeong Eun Shin, Hye-Kyung Jung, Seon-Young Park, Seung Joo Kang, Jung-Wook Kim, Yoo Jin Lee, Hyun Chul Lim, Hee Sun Park, Seong-Jung Kim, Ra Ri Cha, Ki Bae Bang, Chang Seok Bang, Sung Kyun Yim, Seung-Bum Ryoo, Bong Hyeon Kye, Woong Bae Ji, Miyoung Choi, In-Kyung Sung, Suck Chei Choi

{"title":"[Seoul Consensus on Clinical Practice Guidelines for Functional Constipation].","authors":"Kyung Ho Song, Young Sin Cho, Jeong Eun Shin, Hye-Kyung Jung, Seon-Young Park, Seung Joo Kang, Jung-Wook Kim, Yoo Jin Lee, Hyun Chul Lim, Hee Sun Park, Seong-Jung Kim, Ra Ri Cha, Ki Bae Bang, Chang Seok Bang, Sung Kyun Yim, Seung-Bum Ryoo, Bong Hyeon Kye, Woong Bae Ji, Miyoung Choi, In-Kyung Sung, Suck Chei Choi","doi":"10.4166/kjg.2024.156","DOIUrl":"https://doi.org/10.4166/kjg.2024.156","url":null,"abstract":"Chronic constipation is one of the most common digestive diseases encountered in clinical practice. Constipation manifests as a variety of symptoms, such as infrequent bowel movements, hard stools, feeling of incomplete evacuation, straining at defecation, a sense of anorectal blockage during defecation, and use of digital maneuvers to assist defecation. During the diagnosis of chronic constipation, the Bristol Stool Form Scale, colonoscopy, and a digital rectal examination are useful for objective symptom evaluation and differential diagnosis of secondary constipation. Physiological tests for functional constipation have complementary roles. They are recommended for patients who have failed to respond to treatment with available laxatives and those who are strongly suspected of having a defecatory disorder. As new evidence on diagnosing and managing functional constipation emerged, the need to revise the previous guideline was suggested. Therefore, these evidence-based guidelines have proposed recommendations developed using a systematic review and meta-analysis of the treatment options available for functional constipation. The benefits and cautions of new pharmacological agents (such as lubiprostone and linaclotide) and conventional laxatives have been described through a meta-analysis. The guidelines consist of 34 recommendations, including 3 concerning the definition and epidemiology of functional constipation, 9 regarding diagnoses, and 22 regarding management. Clinicians (including primary physicians, general health professionals, medical students, residents, and other healthcare professionals) and patients can refer to these guidelines to make informed decisions regarding managing functional constipation.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"319-344"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Late Referral of Biliary Atresia and Poor Clinical Outcomes. 胆道闭锁转诊晚与临床预后差。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.005

Melinda Masturina, Rendi Aji Prihaningtyas, Bagus Setyoboedi, Sjamsul Arief

{"title":"Late Referral of Biliary Atresia and Poor Clinical Outcomes.","authors":"Melinda Masturina, Rendi Aji Prihaningtyas, Bagus Setyoboedi, Sjamsul Arief","doi":"10.4166/kjg.2025.005","DOIUrl":"https://doi.org/10.4166/kjg.2025.005","url":null,"abstract":"Background/aims: Biliary atresia (BA) is a progressive cholangiopathy in infants that often necessitates liver transplantation. This study aimed to evaluate the impact of delayed referral on clinical and histopathological outcomes in BA cases.Methods: This study was a prospective observational study conducted from January to September 2023 at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.Results: A total of 137 infants with cholestasis were enrolled. Of these, only 85 underwent liver biopsy, with 60 cases (70.6%) confirmed as extrahepatic cholestasis consistent with BA. Among these 60 BA-confirmed patients, 83.3% were referred after 60 days of age. Patients in the late referral group (>60 days) in all cases exhibited higher leukocyte counts, total bilirubin levels, prolonged prothrombin time, and hypoalbuminemia, reflecting a more advanced disease state. Two-phase ultrasonography detected abnormalities in 76.7% of BA-confirmed cases, supporting its potential role as a screening modality in resource-limited settings. Histopathological analysis revealed a significantly higher prevalence of liver fibrosis in patients referred after 60 days (p=0.002), indicating disease progression. Only 9 patients underwent Kasai portoenterostomy, with 8 fatalities due to ascending cholangitis.Conclusions: These findings emphasize the urgent need for earlier detection and referral to improve outcomes in infants with BA.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"382-388"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Diagnostic Work-up and Evaluation of Nonmalignant Ampullary Neoplasms]. 非恶性壶腹部肿瘤的诊断、检查和评价。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.061

Il Sang Shin, Yun Nah Lee, Jong Ho Moon

引用次数: 0

[Endoscopic Management of Ampulla of Vater Tumors]. 壶腹水肿瘤的内镜治疗

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.059

Jong Jin Hyun

引用次数: 0

Combating Post-colonoscopy Colorectal Cancer: Insight from the Trials and Cohort Studies. 对抗结肠镜检查后结直肠癌：来自试验和队列研究的见解。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.006

Wei-Yuan Chang, Han-Mo Chiu

{"title":"Combating Post-colonoscopy Colorectal Cancer: Insight from the Trials and Cohort Studies.","authors":"Wei-Yuan Chang, Han-Mo Chiu","doi":"10.4166/kjg.2025.006","DOIUrl":"https://doi.org/10.4166/kjg.2025.006","url":null,"abstract":"Colorectal cancer (CRC) remains a significant global health concern, being the third most common cancer and the second leading cause of cancer-related death. A colonoscopy examination is central to CRC prevention, enabling screening and adenoma removal. Nevertheless, the emergence of post-colonoscopy colorectal cancer (PCCRC), which is a CRC diagnosed after a colonoscopy that initially found no malignancy, highlights the critical gaps in the quality of current colonoscopy practices. Missed lesions, particularly those with a non-polypoid morphology or in the proximal colon, are the leading cause of PCCRC, accounting for approximately 80% of cases. Efforts to combat PCCRC focused on enhancing the colonoscopy quality through measurable indicators and developing novel technologies to improve the colonoscopy performance. Evidence of how these interventions are associated with the PCCRC risk is critical for endoscopists to obtain the best efficacy from colonoscopy screening. This review summarizes current clinical studies regarding this issue, focusing on randomized control trials and cohort studies to identify the future direction of clinical research on preventing PCCRC.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"286-298"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Safety and Efficacy of Tenofovir Alafenamide in Chronic Hepatitis B: Raising the Need for Studies on Functional Cure-Editorial on "Long-Term Real-World Outcomes of Tenofovir Alafenamide in Chronic Hepatitis B". 替诺福韦Alafenamide治疗慢性乙型肝炎的长期安全性和有效性：提高功能性治疗研究的必要性-关于“替诺福韦Alafenamide治疗慢性乙型肝炎的长期实际结果”的社论。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.062

Soon Kyu Lee

引用次数: 0

[Overview of Nonmalignant Ampulla of Vater Neoplasms]. 【水腹非恶性肿瘤综述】。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.057

Jungnam Lee

{"title":"[Overview of Nonmalignant Ampulla of Vater Neoplasms].","authors":"Jungnam Lee","doi":"10.4166/kjg.2025.057","DOIUrl":"https://doi.org/10.4166/kjg.2025.057","url":null,"abstract":"The ampulla of Vater is a crucial anatomical junction that regulates the flow of bile and pancreatic secretions into the duodenum. Despite the rarity of nonmalignant tumors of this region, they have significant clinical importance. Ampullary adenomas are the most common benign tumors in this area and are considered premalignant lesions with a substantial risk of malignant progression, requiring complete resection upon diagnosis. Ampullary neuroendocrine tumors and gangliocytic paragangliomas are relatively rare but may be associated with hormone production or local metastatic potential, highlighting the need for accurate diagnosis and individualized treatment strategies. Ampullary adenomyomas and other rare benign lesions generally have a benign course but can clinically and radiologically mimic a malignancy, often necessitating surgical resection for a definitive diagnosis. This review comprehensively summarizes the anatomy of the ampulla of Vater and the pathological features and clinical significance of nonmalignant ampullary tumors. Continued research and multidisciplinary collaboration are crucial for developing effective treatment strategies and improving patient outcomes in this complex field.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"248-252"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concomitant Lupus Enteritis and Lupus Cystitis: Case Report and Literature Review. 狼疮肠炎及狼疮膀胱炎合并病例报告及文献复习。

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi Pub Date : 2025-07-25 DOI: 10.4166/kjg.2025.015

Doan Nguyen, Huong Nguyen, Uyen Tran, Luu Le

{"title":"Concomitant Lupus Enteritis and Lupus Cystitis: Case Report and Literature Review.","authors":"Doan Nguyen, Huong Nguyen, Uyen Tran, Luu Le","doi":"10.4166/kjg.2025.015","DOIUrl":"https://doi.org/10.4166/kjg.2025.015","url":null,"abstract":"Lupus enteritis and lupus cystitis share a common etiology, characterized by smooth muscle dysmotility resulting from immune complex-mediated damage. This paper describes a case of a patient presenting with concomitant lupus enteritis and lupus cystitis without a prior systemic lupus erythematosus (SLE) diagnosis. The onset of symptoms occurred five months earlier with frequent loose stools, persistent abdominal pain, nausea, vomiting, and a significant weight loss of 16 kg. The patient presented with abdominal pain, distension, dysuria, and urinary urgency lasting for a week. A computed tomography scan upon admission revealed diffuse thickening of the gastric, intestinal, and colon walls, as well as cystitis, ureteral dilation, and bilateral hydronephrosis. Extensive screening excluded infections and other autoimmune diseases, confirming SLE according to the 2019 EULAR/ACR criteria, with a high SLE disease activity index score of 18 points. Treatment with corticosteroids resulted in symptomatic improvement in the intestinal and bladder symptoms and other organ involvements. This case highlights the significance of recognizing autoimmune causes, such as lupus, in cases of widespread gastrointestinal and bladder inflammation.","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":"85 3","pages":"395-403"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144710365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0