The Journal of dermatology最新文献_第3页

Guidelines for the management of drug-induced hypersensitivity syndrome 2023.

The Journal of dermatology Pub Date : 2025-02-03 DOI: 10.1111/1346-8138.17609

Yoshiko Mizukawa, Natsumi Hama, Hiroyuki Niihara, Fumi Miyagawa, Hideo Hashizume, Mikiko Tohyama, Hayato Takahashi, Hideaki Watanabe, Manabu Ohyama, Yukie Yamaguchi, Tatsuyoshi Kawamura, Takashi Nomura, Kenji Kabashima, Hirohiko Sueki, Eishin Morita, Riichiro Abe, Hideo Asada

{"title":"Guidelines for the management of drug-induced hypersensitivity syndrome 2023.","authors":"Yoshiko Mizukawa, Natsumi Hama, Hiroyuki Niihara, Fumi Miyagawa, Hideo Hashizume, Mikiko Tohyama, Hayato Takahashi, Hideaki Watanabe, Manabu Ohyama, Yukie Yamaguchi, Tatsuyoshi Kawamura, Takashi Nomura, Kenji Kabashima, Hirohiko Sueki, Eishin Morita, Riichiro Abe, Hideo Asada","doi":"10.1111/1346-8138.17609","DOIUrl":"https://doi.org/10.1111/1346-8138.17609","url":null,"abstract":"Drug-induced hypersensitivity syndrome (DIHS) is one of the severe drug eruptions accompanied by fever and multiple organ dysfunction, and it is induced by a relatively limited range of drugs, including anticonvulsants. A distinctive feature of this condition is its association with the reactivation of herpes viruses, particularly human herpesvirus 6. The pathogenesis involves two key factors: drug allergy and herpesvirus reactivation. DIHS is often challenging to diagnose in its early stages, and its clinical course varies widely, ranging from relatively mild to life-threatening cases. Additionally, unexpected complications, such as autoimmune diseases, may occur during the convalescent phase. As a result, diagnosing, treating, and predicting the prognosis of DIHS remain complex issues. In response to these challenges, the Ministry of Health, Labour and Welfare Study Group on Severe Erythema Multiforme has taken the lead in developing new guidelines for the management of DIHS. These guidelines aim to support clinical practice by providing up-to-date, evidence-based information on the diagnosis, treatment, and prognosis of DIHS.","PeriodicalId":94236,"journal":{"name":"The Journal of dermatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Significance of cell adhesion molecule 1 expression in mycosis fungoides: Diagnostic implications and clinical correlations.

The Journal of dermatology Pub Date : 2025-02-03 DOI: 10.1111/1346-8138.17652

Akihiko Yuki, Riichiro Abe

引用次数: 0

The impact of antibiotic therapy in psoriasis patients with active streptococcal infection: A prospective study.

The Journal of dermatology Pub Date : 2025-02-03 DOI: 10.1111/1346-8138.17645

D Bonciani, C Della Bella, A Corrà, A Galano, G Vaggelli, S Tapinassi, A Grassi, E Mantengoli, A Coi, L Quintarelli, E B Mariotti, C Aimo, V Ruffo di Calabria, E Garufi, V Volpi, A Verdelli, G M Rossolini, A Bartoloni, M M D'Elios, M Caproni

{"title":"The impact of antibiotic therapy in psoriasis patients with active streptococcal infection: A prospective study.","authors":"D Bonciani, C Della Bella, A Corrà, A Galano, G Vaggelli, S Tapinassi, A Grassi, E Mantengoli, A Coi, L Quintarelli, E B Mariotti, C Aimo, V Ruffo di Calabria, E Garufi, V Volpi, A Verdelli, G M Rossolini, A Bartoloni, M M D'Elios, M Caproni","doi":"10.1111/1346-8138.17645","DOIUrl":"https://doi.org/10.1111/1346-8138.17645","url":null,"abstract":"The association between psoriasis and streptococcal infection has been widely explored in both children and adults. However, the exact impact of Streptococcus pharyngeal infection on the course of psoriasis is not fully comprehended. This study explored the impact of Streptococcus pharyngeal infection on psoriasis and investigated the effectiveness of systemic antibiotic therapy in conjunction with standard topical treatment for psoriatic patients with concomitant streptococcal throat infection. The research involved 115 patients with mild-to-moderate psoriasis, clinically assessed using the Psoriasis Area and Severity Index (PASI). Patients with active streptococcal infection were administered adjunctive systemic antibiotic therapy along with standard local treatment for psoriasis, while psoriasis patients without evidence of infection received the local topical treatment only. Streptococcal infections were more common in psoriasis patients compared to healthy controls. A group of psoriasis patients with active streptococcal throat infections, treated with antibiotics in addition to standard topical psoriasis therapy, did not show any difference in PASI score reduction compared to those without evidence of active infection. While our study did not show a statistically significant reduction in PASI scores in psoriasis patients with streptococcal throat infections treated with antibiotics, it highlights the complex interaction between infection and psoriasis. Larger studies with longer follow-up may better clarify this relationship, contributing to stronger evidence for or against the use of antibiotics in managing psoriasis triggered by streptococcal infections.","PeriodicalId":94236,"journal":{"name":"The Journal of dermatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of warts in toe webs due to HPV type 7: Case report and literature review.

The Journal of dermatology Pub Date : 2025-02-01 DOI: 10.1111/1346-8138.17653

Mei Tochigi, Yuko Takamiya, Sawako Ochiai, Kazushi Anzawa, Kiyohiro Tsutsui, Akira Shimizu

引用次数: 0

A case of peripheral T-cell lymphoma NOS presenting as a subcutaneous tumor with favorable prognosis.

The Journal of dermatology Pub Date : 2025-02-01 DOI: 10.1111/1346-8138.17644

Kenichiro Mae, Ryokichi Irisawa, Hiroko Wakimoto, Kazutoshi Harada, Toshihisa Hamada

引用次数: 0

Pemphigoid with autoantibodies exclusively reacting with γ2-subunit of laminin-332 in a patient with psoriasis vulgaris.

The Journal of dermatology Pub Date : 2025-02-01 DOI: 10.1111/1346-8138.17650

Tatsuro Morita, Koremasa Hayama, Norito Ishii, Hiroshi Koga, Hideki Fujita

引用次数: 0

Associations of chronic kidney disease with hidradenitis suppurativa: A bidirectional Mendelian randomization study.

The Journal of dermatology Pub Date : 2025-02-01 DOI: 10.1111/1346-8138.17655

Yang Xu, Yiling Yang, Weisheng Zhan, Juhua Zhao

引用次数: 0

Cutaneous squamous carcinoma with pulmonary metastasis with cavity formation successfully treated with nivolumab.

The Journal of dermatology Pub Date : 2025-01-29 DOI: 10.1111/1346-8138.17649

Kazuna Morito, Soichiro Kado, Hirofumi Okada, Atsuko Sato, Koji Kamiya, Takeo Maekawa, Mamitaro Ohtsuki, Mayumi Komine

引用次数: 0

Real-world 52-week effectiveness of deucravacitinib in psoriasis: A stratified analysis by age and body mass index.

The Journal of dermatology Pub Date : 2025-01-28 DOI: 10.1111/1346-8138.17617

Teppei Hagino, Marina Onda, Hidehisa Saeki, Eita Fujimoto, Naoko Kanda

{"title":"Real-world 52-week effectiveness of deucravacitinib in psoriasis: A stratified analysis by age and body mass index.","authors":"Teppei Hagino, Marina Onda, Hidehisa Saeki, Eita Fujimoto, Naoko Kanda","doi":"10.1111/1346-8138.17617","DOIUrl":"https://doi.org/10.1111/1346-8138.17617","url":null,"abstract":"Deucravacitinib, an oral tyrosine kinase 2 inhibitor, is effective for psoriasis. However, long-term real-world effectiveness stratified by age and body mass index (BMI) has not been precisely examined. This study aimed to evaluate 52-week real-world effectiveness of deucravacitinib in psoriasis patients, stratified by age (≥65 years vs <65 years) and BMI (≥25 vs <25). A prospective study was conducted from December 2022 to August 2024, involving 107 Japanese patients aged ≥15 years with moderate to severe psoriasis. Patients received 6 mg of deucravacitinib daily for 52 weeks. Therapeutic effectiveness was evaluated by the achievement rates of Psoriasis Area and Severity Index (PASI) 75, PASI 90, PASI 100, and other key clinical indices. Data were stratified by age and BMI. Mean PASI scores decreased until week 52 similarly in all patients' groups stratified by age or BMI. The achievement rates of PASI 75, PASI 90, and PASI 100 at week 52 were 86.36%, 59.09%, and 13.64% in patients aged ≥65 years, while they were 86.36%, 65.22%, and 39.13% in patients aged <65 years, respectively, showing a slightly lower rate of PASI 100 in patients ≥65 years. The achievement rates of PASI 75, PASI 90, and PASI 100 at week 52 were 81.82%, 73.33%, and 18.18% in patients with BMI ≥25, while they were 88.24%, 82.86%, and 29.41% in patients with BMI < 25, respectively, and these rates at weeks 4, 16, 24, and 40 were slightly lower in patients with BMI ≥25. Deucravacitinib improved clinical indices of psoriasis patients during a 52-week period in all patients' groups stratified by age or BMI. The present results indicate that deucravacitinib may be effective for elderly psoriasis patients as well as younger or middle-aged patients, while effectiveness in patients with BMI ≥25 may be slightly lower compared with those with BMI < 25.","PeriodicalId":94236,"journal":{"name":"The Journal of dermatology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of acquired partial anhidrosis localized on the palms.

The Journal of dermatology Pub Date : 2025-01-28 DOI: 10.1111/1346-8138.17640

Shuta Yoshitani, Toshihiro Otsuka, Shinichi Moriwaki, Atsushi Fukunaga

引用次数: 0