María Cantero-Gómez, Jorge Vicente-Sanchez, María Dolores Oteo-Calatayud, Wenceslao Piedra-Cascón, Carlos Oteo-Morilla
{"title":"Comparative Clinical Study of Two Tooth-Whitening Protocols: A Randomized Clinical Trial. Part 2.","authors":"María Cantero-Gómez, Jorge Vicente-Sanchez, María Dolores Oteo-Calatayud, Wenceslao Piedra-Cascón, Carlos Oteo-Morilla","doi":"10.11607/prd.7106","DOIUrl":"10.11607/prd.7106","url":null,"abstract":"<p><p>This study clinically evaluated the efficacy of two different home tooth-whitening protocols to determine which one is more effective by applying the whitening gel every 48 hours or every 72 hours for 6 weeks. The differences in tooth sensitivity were also analyzed. A sample of 72 patients were randomly divided into four groups: In group A (n = 24), 16% carbamide peroxide (Pola Night, SDI Limited) was applied every 48 hours for 6 weeks; in group B (n = 24), 16% carbamide peroxide was applied every 72 hours for 6 weeks; in group C (control; n = 12), a placebo gel without peroxide (glycerin gel) was applied every 48 hours for 6 weeks; and in group D (control; n = 12), a placebo gel without peroxide (glycerin gel) was applied every 72 hours for 6 weeks. To compare the groups, color measurements were made using a spectrophotometer. For statistical analysis, ANOVA with Bonferroni test was used. The confidence interval (CI) was set at 95% (P ≤ .05). No statistically significant differences were found between applying 16% carbamide peroxide every 48 hours and every 72 hours for 6 weeks (P > .05). The study concluded that 16% carbamide peroxide was equally effective when applied using both protocols.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"199-207"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Cairo, Raffaele Cavalcanti, Luigi Barbato, Michele Nieri, Walter Castelluzzo, Maria di Martino, Andrea Pilloni
{"title":"Polynucleotides and Hyaluronic Acid (PN-HA) Mixture With or Without Deproteinized Bovine Bone Mineral as a Novel Approach for the Treatment of Deep Infrabony Defects: A Retrospective Case Series.","authors":"Francesco Cairo, Raffaele Cavalcanti, Luigi Barbato, Michele Nieri, Walter Castelluzzo, Maria di Martino, Andrea Pilloni","doi":"10.11607/prd.7065","DOIUrl":"10.11607/prd.7065","url":null,"abstract":"<p><p>A mixture of polynucleotides and hyaluronic acid (PN-HA) has shown several modulating effects in the healing process. This study aimed to assess the safety and clinical performance of PN-HA alone or in association with deproteinized bovine bone mineral (DBBM) with papillary preservation flap (PPFs) in the treatment of residual pockets. A total of 43 patients with 55 infrabony defects were recruited; 30% were smokers. The mean baseline probing depth (PD) was 7.7 ± 1.9 mm with a corresponding mean recession (Rec) of 1.9 ±. 1.3 mm. The infrabony defect depth at the surgical measurement was 5.2 ± 2.1 mm. DBBM was applied at 56% of the defects, as they were determined to be noncontained defects based on clinical judgment. Healing was uneventful at all sites. After 1 year, PD reduction was 4.4 ± 1.8 mm, with a Rec increase of 1.0 ± 0.8 mm. The radiographic bone fill was 3.5 ±1.9 mm. The multilevel analysis showed that an absence of smoking habits was associated with improved PD reduction (P = .026) and bone gain (P = .039). PN-HA mixture is a safe product for periodontal surgery and seems to promote clinical benefits in the treatment of residual pockets associated with infrabony defects.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"153-163"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139743027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ZAGA Double Pedicle Palatal Flap for Soft Tissue Management in Zygomatic Surgery.","authors":"Carlos Aparicio, Arnau Aparicio","doi":"10.11607/prd.7048","DOIUrl":"10.11607/prd.7048","url":null,"abstract":"<p><p>Oral rehabilitation of the atrophic maxilla using prostheses anchored by zygomatic implants (ZIs) is a well-documented process. To prevent the risk of sinusitis and/or oroantral communication, the placement of ZIs with an externalized path has been proposed. In cases where sealing the implant neck depends exclusively on a hemidesmosome junction, there is a risk of dehiscence in the soft tissue that can lead to esthetic problems, bone resorption, oroantral communication, cellulitis, and even orbital infection. To avoid soft tissue recession in implants placed buccal to the remaining ridge, the simplest procedure is to ensure good buccal coverage of the implant via keratinized tissue. Use of a double pedicle palatal flap is proposed to increase the keratinized tissue buccal to the implant while facilitating the incision closure by primary intention.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"239-252"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139743030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Francisco Peña-Cardelles, Fernando Núñez Díaz, Elli Kotina, Ignacio Pedrinaci, Alejandro Lanis, German O Gallucci
{"title":"The Use of CAD/CAM Templates in a Lateral Sinus Floor Augmentation Procedure: A Systematic Review.","authors":"Juan Francisco Peña-Cardelles, Fernando Núñez Díaz, Elli Kotina, Ignacio Pedrinaci, Alejandro Lanis, German O Gallucci","doi":"10.11607/prd.6919","DOIUrl":"10.11607/prd.6919","url":null,"abstract":"<p><p>Maxillary sinus floor augmentation (SFA) is a procedure known for its long-term success and predictable outcomes. However, sinus membrane perforation remains the most common complication associated with this procedure. This systematic review aims to determine the presence of complications during maxillary SFA procedures using CAD/CAM surgical templates. An electronic search was carried out in MEDLINE (via PubMed), Web of Science, and Scopus. A descriptive analysis of the data was performed. Studies that performed lateral SFA were included, and the CAD/CAM surgical template design and the intraoperative complications were registered. A total of 13 studies (7 case reports, 4 case series, and 2 randomized clinical trials) and a total of 94 lateral SFA procedures (84 using CAD/CAM templates and 10 without templates) were included. Three of the 84 maxillary SFA procedures using a CAD/CAM template presented intraoperative complications. Maxillary SFA performed using CAD/CAM surgical templates could be related to low rates of complications. However, due to the heterogeneity of the included articles, more standardized studies are needed to confirm these outcomes.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"253-261"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139743028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Last Molar-Entire Pad Preservation Technique (L-EPPT) as a Regenerative Surgical Approach for Combined Distal Intrabony Defects and Furcation Involvement: Case Reports.","authors":"Dai Kawanabe, Ryutaro Kuraji","doi":"10.11607/prd.7024","DOIUrl":"10.11607/prd.7024","url":null,"abstract":"<p><p>Primary wound closure is the most important factor in successful periodontal tissue regeneration when using biomaterials. However, in the distal region of the last molar, there is concern that direct surgical access to an intraosseous defect may induce biomaterial leakage, impair the blood supply, and make healing difficult. This case series introduces the last molar-entire pad preservation technique (L-EPPT), which was designed to preserve the gingiva of the last molar centrum and secure the operative field of the furcation and distal bone defects, thereby providing an optimal environment for wound healing for regenerative therapy. This technique for preservation of the distal gingiva was applied in two cases involving the combination of a buccal class II furcation defect and a two- to three-wall intrabony defect in the last molar for the use of a combination of bone graft and enamel matrix derivatives in periodontal regeneration. Clinical outcomes were recorded at 18 months (Case 1) and 8 months (Case 2) after surgery. In both cases, the class II furcation defects were completely closed, and the probing pocket depth was improved (< 3 mm) with no bleeding on probing. Further research is warranted to verify the efficacy of this technique.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"173-183"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139479215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Entire Papilla Preservation Technique with Recombinant Human Fibroblast Growth Factor-2 and Autogenous Bone Grafting in the Treatment of Isolated, Noncontained Intrabony Defects: Case Report with a 5-Year Follow-up.","authors":"Yoshitaka Nara, Yudai Ogawa, Serhat Aslan","doi":"10.11607/prd.7038","DOIUrl":"10.11607/prd.7038","url":null,"abstract":"<p><p>Regenerative periodontal surgery is an effective procedure for the treatment of intrabony defects. Various flap designs that preserve defect-associated interdental papillae have been proposed to improve early wound stability. This case report describes the long-term results of a regenerative treatment in a severely compromised mandibular canine using the entire papilla preservation technique. Surgical access was provided by a single buccal vertical incision without any papilla incision. A combination of autogenous bone harvested from the same surgical site and recombinant human fibroblast growth factor-2 was applied to a noncontained intrabony defect following the removal of granulation tissue. The surgical site was closed with single interrupted sutures. The clinical outcomes after 5 years showed stable pocket closure without any increase in gingival recession, highlighting the potential of the entire papilla preservation technique with the use of combined biomaterials.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"165-171"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gonzalo Blasi, Lise Maury, Ada Lapedra, Javi Vilarrasa, Alberto Monje, Jose Nart
{"title":"Suture Removal Timing and its Effect on Root Coverage: A Randomized Clinical Trial.","authors":"Gonzalo Blasi, Lise Maury, Ada Lapedra, Javi Vilarrasa, Alberto Monje, Jose Nart","doi":"10.11607/prd.7525","DOIUrl":"https://doi.org/10.11607/prd.7525","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of suture removal timing on the clinical outcomes of root coverage procedures.</p><p><strong>Materials and methods: </strong>In this single-blinded, randomized prospective clinical trial, patients presenting with multiple gingival recessions were allocated into three groups based on the timing of suture removal post-surgery: 1 week (TSR1), 2 weeks (TSR2), and 3 weeks (TSR3). Primary outcomes measured included Percentage of Root Coverage (%RC) and Complete Root Coverage (CRC), among other clinical outcomes. Data were collected at baseline and at 3 and 6 months postoperatively.</p><p><strong>Results: </strong>At 6 months, the %RC was 58.4% (TSR1), 91.5% (TSR2), and 75.7% (TSR3). TSR2 achieved a 28.9% higher %RC than TSR1, while no significant differences were found between TSR2 and TSR3. CRC was 38.2% (TSR1), 78.6% (TSR2), and 62.5% (TSR3). TSR2 resulted in a 5.92-fold increase in CRC compared to TSR1, whereas no significant difference was observed between TSR2 and TSR3.</p><p><strong>Conclusions: </strong>This suggests that a 2-week period before suture removal may optimize root coverage outcomes. However, extending suture removal timing beyond 2 weeks did not confer additional benefits.These findings are specific to the use of polypropylene and the CAF plus connective tissue graft. (ClinicalTrials.gov Identifier [NCT04826653]).</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"1-26"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-Immediacy for Non-Destructive Equilibrium: Surgical, Osteogenic, and Prosthetic Innovations in Full-Arch Implant Rehabilitation with Terminal Dentitions - A Three-Year Case Report.","authors":"Young K Kim","doi":"10.11607/prd.7518","DOIUrl":"https://doi.org/10.11607/prd.7518","url":null,"abstract":"<p><p>Full-arch implant rehabilitation - necessitating a holistic, transdisciplinary approach - has been one of the most rapidly advancing disciplines in implant dentistry, driven by rising standards and modern technological advancements. Despite indicated cases and genuine efforts to improve efficiency, the current trend of immediacy or 'teeth-in-a-day' protocol may have unintentionally veiled a more conservative, predictable, and practical potential in wound healing process, esthetics, and occlusion. Through a more phased approach utilizing terminal dentitions as strategic abutments, this case report of three years follow-up emphasizes the leverage of natural biological phenomena in tissue maturation, remodeling, and condensation, along with prosthetic sophistications focusing on its meticulousness in execution and long-range trajectory success. This workflow actualizes a high-quality level of craftsmanship with surgical and prosthetic innovations, introduced as a 're-tightening bilateral sling periosteal mattress suture' (RBSPMS) concept for intermittent tensocompressive mechanotransduction-induced guided bone regeneration and 'LegOvate' protocol for seamless loading of prosthetic conversions, emphasizing the intricate reciprocity between physiology and biomechanics for a primary goal of non-destructive equilibrium.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"1-32"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Outcomes of Periodontal Regenerative Therapy with Double-Sided Entire Papilla Preservation (DEPP) Technique for Intrabony Defects: A Case-Series with 12-Month Follow-Up.","authors":"Yudai Ogawa, Serhat Aslan, Hiroaki Goto, Dai Kawanabe, Takahiko Nagai, Shogo Maekawa, Tomohiro Ishikawa, Atsushi Saito, Pierpaolo Cortellini, Kentaro Imamura","doi":"10.11607/prd.7532","DOIUrl":"https://doi.org/10.11607/prd.7532","url":null,"abstract":"<p><p>Double-sided Entire Papilla Preservation (DEPP) technique was designed to allow access into a bone defect without compromising the integrity of papilla, when the defect extends to palatal/lingual side. This case-series study aimed to evaluate the clinical and radiographic outcomes of periodontal regenerative therapy using DEPP technique for intrabony defects. DEPP was performed with two vertical incisions on both the buccal and palatal sites to access the bone defect. After debridement, recombinant human fibroblast growth factor 2 or enamel matrix derivatives were used in combination with carbonate apatite (CO3Ap) or deproteinized bovine bone mineral (DBBM) to treat the defect. Periodontal parameters were evaluated at baseline, 6, and 12 months postoperatively. Values for clinical attachment level (CAL) and probing depth (PD) were statistically significantly improved compared with baseline at 6 months (P < 0.05) and 12 months (P < 0.01) following surgery. At 12 months, the mean PD reduction was 5.0 ± 1.4 mm and CAL gain was 5.3 ± 1.8 mm. According to the Composite Outcome Measure, the outcomes of the treated sites were considered 'successful'. This case series demonstrates that DEPP can be effectively combined with regenerative therapy for intrabony defects, yielding favorable clinical outcomes with minimal surgical complications.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"1-28"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-Term Pulp Vitality Preservation by Root Debridement Excluding the Apical 2 mm in Severe Periodontal Bone Defect Beyond the Root Apex: A 5-Year Case Report.","authors":"Yuichiro Ihara, Satoru Morikawa, Taneaki Nakagawa","doi":"10.11607/prd.7582","DOIUrl":"10.11607/prd.7582","url":null,"abstract":"<p><p>Periodontal regenerative therapy offers new options for treating teeth with severe bone loss. However, debate persists over preventive root canal treatment when bone resorption extends beyond the root apex. This report examines periodontal regeneration and pulp vitality preservation, challenging conventional treatment. A 65-year-old man presented with 10 mm periodontal pockets and bone resorption extending beyond the root apex of tooth #42. Pulp vitality was confirmed, and periodontal regenerative therapy was performed without preventive root canal treatment. Root debridement excluding the apical 2 mm was performed and verified using cone-beam computed tomography (CBCT), followed by application of enamel matrix derivative (Emdogain®), deproteinized bovine bone (Bio-Oss®), and a collagen membrane. At 6 months, probing depths decreased from 10 mm to 3 mm without bleeding on probing. Radiographs showed bone regeneration. At 5 years, probing depths remained stable at ≤ 3 mm, and CBCT confirmed long-term bone stability. Pulp vitality tests remained positive. The findings from this case suggest that root debridement excluding the apical 2 mm and precise regenerative techniques can promote periodontal regeneration and maintain pulp vitality, questioning the need for routine preventive endodontics. Further research is needed to establish protocols for complex cases.</p>","PeriodicalId":94231,"journal":{"name":"The International journal of periodontics & restorative dentistry","volume":"0 0","pages":"1-25"},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}