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Bedside phenotypic markers of marrow expansion identify thalassemia patients with degraded bone microarchitecture and increased fracture prevalence. 骨髓扩增的床边表型标记识别地中海贫血患者的骨微结构退化和骨折发生率增加。
IF 1.8
The American journal of the medical sciences Pub Date : 2026-07-17 DOI: 10.1016/j.amjms.2026.07.006
Nattiya Teawtrakul, Dueanchonnee Sribenjalak, Daris Theerakulpisut, Nipith Charoenngam, Chatlert Pongchaiyakul
{"title":"Bedside phenotypic markers of marrow expansion identify thalassemia patients with degraded bone microarchitecture and increased fracture prevalence.","authors":"Nattiya Teawtrakul, Dueanchonnee Sribenjalak, Daris Theerakulpisut, Nipith Charoenngam, Chatlert Pongchaiyakul","doi":"10.1016/j.amjms.2026.07.006","DOIUrl":"10.1016/j.amjms.2026.07.006","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148475085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Providers' perspectives on hospital-based tobacco treatment efforts. 提供者对医院烟草治疗工作的看法。
IF 1.8
The American journal of the medical sciences Pub Date : 2026-06-27 DOI: 10.1016/j.amjms.2026.06.022
MacKenzie Firek, Ellen N Esposito, Alana M Rojewski, Andrew D Schreiner, Marc Heincelman, Benjamin A Toll, Emily C Ware
{"title":"Providers' perspectives on hospital-based tobacco treatment efforts.","authors":"MacKenzie Firek, Ellen N Esposito, Alana M Rojewski, Andrew D Schreiner, Marc Heincelman, Benjamin A Toll, Emily C Ware","doi":"10.1016/j.amjms.2026.06.022","DOIUrl":"10.1016/j.amjms.2026.06.022","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148341732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to: "Grit in the intensive care unit: Rethinking the construct in pulmonary and critical care medicine". 回应：“重症监护室的勇气：对肺部和危重病医学建设的反思”。
IF 1.8
The American journal of the medical sciences Pub Date : 2026-06-13 DOI: 10.1016/j.amjms.2026.06.014
Alan W Hu, Thomas J Beckman, Diana J Kelm
{"title":"Response to: \"Grit in the intensive care unit: Rethinking the construct in pulmonary and critical care medicine\".","authors":"Alan W Hu, Thomas J Beckman, Diana J Kelm","doi":"10.1016/j.amjms.2026.06.014","DOIUrl":"10.1016/j.amjms.2026.06.014","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148255274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Projected trends and disparities in Hepatitis C-associated cirrhosis mortality in the United States through 2035. 到2035年美国丙型肝炎相关肝硬化死亡率的预测趋势和差异
IF 1.8
The American journal of the medical sciences Pub Date : 2026-06-11 DOI: 10.1016/j.amjms.2026.06.010
Muhammad Ali Tariq, Minhail Khalid Malik, Aiman Fatima Malik, Madiha Khan, Zunaira Ahsan Majoka, Mohammad Sadan Malik, Hamza Amin
{"title":"Projected trends and disparities in Hepatitis C-associated cirrhosis mortality in the United States through 2035.","authors":"Muhammad Ali Tariq, Minhail Khalid Malik, Aiman Fatima Malik, Madiha Khan, Zunaira Ahsan Majoka, Mohammad Sadan Malik, Hamza Amin","doi":"10.1016/j.amjms.2026.06.010","DOIUrl":"10.1016/j.amjms.2026.06.010","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148229969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rethinking the Construct of Psychological Grit in Critical Care Medicine. 重症监护病房中的勇气：对肺部和危重症医学结构的再思考。
IF 1.8
The American journal of the medical sciences Pub Date : 2026-04-28 DOI: 10.1016/j.amjms.2026.04.011
Salem Harry-Hernandez, Victor N Oboli, Shyoko Honiden
{"title":"Rethinking the Construct of Psychological Grit in Critical Care Medicine.","authors":"Salem Harry-Hernandez, Victor N Oboli, Shyoko Honiden","doi":"10.1016/j.amjms.2026.04.011","DOIUrl":"10.1016/j.amjms.2026.04.011","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147825182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments on 'Effect of therapeutic lifestyle changes on patients with overweight/obesity and non-alcoholic fatty liver disease: A randomized controlled trial'. 对“治疗性生活方式改变对超重/肥胖和非酒精性脂肪肝患者的影响：一项随机对照试验”的评论。
IF 1.8
The American journal of the medical sciences Pub Date : 2026-04-21 DOI: 10.1016/j.amjms.2026.04.007
Shuyi Chen
{"title":"Comments on 'Effect of therapeutic lifestyle changes on patients with overweight/obesity and non-alcoholic fatty liver disease: A randomized controlled trial'.","authors":"Shuyi Chen","doi":"10.1016/j.amjms.2026.04.007","DOIUrl":"10.1016/j.amjms.2026.04.007","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147793649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In memoriam: Richard W McCallum. 纪念：理查德·麦卡勒姆。
IF 1.8
The American journal of the medical sciences Pub Date : 2026-01-01 Epub Date: 2025-10-16 DOI: 10.1016/j.amjms.2025.10.005
C Mel Wilcox
{"title":"In memoriam: Richard W McCallum.","authors":"C Mel Wilcox","doi":"10.1016/j.amjms.2025.10.005","DOIUrl":"https://doi.org/10.1016/j.amjms.2025.10.005","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":"371 1","pages":"1"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
481 Post-partum spontaneous coronary artery dissection with a history of takotsubo cardiomyopathy 481例产后自发性冠状动脉剥离伴takotsubo型心肌病病史
The American journal of the medical sciences Pub Date : 2025-01-15 DOI: 10.1016/s0002-9629(25)00487-2
Sinjini Biswas, Tariq Farhad, Asima Karim
{"title":"481 Post-partum spontaneous coronary artery dissection with a history of takotsubo cardiomyopathy","authors":"Sinjini Biswas, Tariq Farhad, Asima Karim","doi":"10.1016/s0002-9629(25)00487-2","DOIUrl":"https://doi.org/10.1016/s0002-9629(25)00487-2","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":"369 1","pages":"S313-S314"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
WITHDRAWN: The closed loop of the circCLIP2/miR-361-3p/STAT2 signaling axis regulates the progression of cervical cancer. circCLIP2/miR-361-3p/STAT2信号轴的闭环调节宫颈癌的进展。
IF 1.8
The American journal of the medical sciences Pub Date : 2024-08-07 DOI: 10.1016/j.amjms.2024.08.002
Qian Zhang, Wang Cai
{"title":"WITHDRAWN: The closed loop of the circCLIP2/miR-361-3p/STAT2 signaling axis regulates the progression of cervical cancer.","authors":"Qian Zhang, Wang Cai","doi":"10.1016/j.amjms.2024.08.002","DOIUrl":"10.1016/j.amjms.2024.08.002","url":null,"abstract":"<p><strong>Background: </strong>Circular RNAs (circRNAs) are involved in tumorigenesis and the progression of cancer through various pathways. However, the detailed regulatory mechanisms of circRNAs in cervical cancer are not fully understood. The present study was designed to explore the biological functions and potential mechanisms of circCLIP2 (has_circ_0001717) in cervical cancer.</p><p><strong>Methods: </strong>The expression profiles of circRNAs in cancerous and adjacent normal tissues of cervical cancer patients were examined using RNA sequencing. Gain- and loss-of-function experiments were carried out to determine the biological functions of circCLIP2 in the proliferation, invasion, migration and apoptosis of cervical cancer cells. qRT-PCR was also used to evaluate the expression of circCLIP2, miR-361-3p and STAT2 in cervical cancer cells. The protein levels of STAT2 were determined by western blotting.</p><p><strong>Results: </strong>CircCLIP2 was identified as the most down-regulated molecule in the cancerous tissues of cervical cancer patients compared to the adjacent normal tissues. Moreover, the levels of circCLIP2 was decreased in cervical cancer patients with metastasis and advanced tumour stage, and patients with high-circCLIP2-expression exhibited poorer survival rate. In addition, over-expression of circCLIP2 suppressed the proliferation, invasion and migration of cervical cancer cells, whereas cell apoptosis was enhanced. Moreover, down-regulated circCLIP2 functioned as the sponge of miR-361-3p, which reduced the expression of STAT2. Furthermore, knockdown of STAT2 inhibited the expression of circCLIP2 at the transcriptional level.</p><p><strong>Conclusion: </strong>The circCLIP2/miR-361-3p/STAT2 signalling could mediate the progression of cervical cancer. CircCLIP2 may become a novel target for the diagnosis and treatment of cervical cancer.</p>","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Neck Circumference and Bone Mineral Loss: A Cross-sectional Study in Sichuan Province in China. 颈围与骨矿物质流失的关系：一项在中国四川省进行的横断面研究。
The American journal of the medical sciences Pub Date : 2024-05-01 DOI: 10.1016/j.amjms.2024.05.004
Qing Wen, Xiaoran Zhang, Yunjiao Yang, Huizhen Chen, Xuke Han, Qiu Chen
{"title":"Association Between Neck Circumference and Bone Mineral Loss: A Cross-sectional Study in Sichuan Province in China.","authors":"Qing Wen, Xiaoran Zhang, Yunjiao Yang, Huizhen Chen, Xuke Han, Qiu Chen","doi":"10.1016/j.amjms.2024.05.004","DOIUrl":"https://doi.org/10.1016/j.amjms.2024.05.004","url":null,"abstract":"","PeriodicalId":94223,"journal":{"name":"The American journal of the medical sciences","volume":"28 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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