{"title":"Pragmatic strategy for vitamin and micronutrient supplementation after metabolic and bariatric surgery.","authors":"Hélène Chappard, Ouidad Sami, Imen Sakka, Suzette Coelho, Thierry Dupré, Muriel Coupaye, David Moszkowicz, Séverine Ledoux","doi":"10.1016/j.soard.2025.08.023","DOIUrl":"https://doi.org/10.1016/j.soard.2025.08.023","url":null,"abstract":"<p><strong>Background: </strong>Nutritional deficiencies are frequent after metabolic and bariatric surgery (MBS) and systematic addition of vitamin B12, iron, calcium, and vitamin D to standard multivitamin tablets is recommended. However, there are still uncertainties because supporting data are few and compliance with a large number of tablets is low.</p><p><strong>Objectives: </strong>To assess the need for additional supplements using a supplementation based on biological assays after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG).</p><p><strong>Methods: </strong>Consecutive patients (N = 313: 179 RYGB/134 SG; 86% women, mean age 44.1 ± 10.3 years, Body mass index 43.5 ± 6.6 kg/m<sup>2</sup>) who underwent a nutritional assessment, before and at 6, 12, and 36 months after MBS, were studied. Multivitamin tablets were systematically prescribed after MBS, and additional supplements were introduced following a standardized protocol in the case of deficiency.</p><p><strong>Setting: </strong>University Hospital, France.</p><p><strong>Results: </strong>Although the number of patients taking additional supplements increased by more after RYGB than after SG (58.7% vs 43.3%, P < .01), the mean number of deficits did not increase and was similar at 3 years (3.7 vs 3.4, Ns). The frequency of nutritional symptoms was also similar after both procedures, the most common being hair loss, while neurological symptoms were unusual and mild. Anemia was infrequent, but secondary hyperparathyroidism was frequent after RYGB (23% vs 9% after SG, P < .01).</p><p><strong>Conclusions: </strong>A personalized supplementation strategy adapted to biological parameters, in patients followed regularly up to 3 years after MBS, may reduce the number of nutritional supplements without increasing the number of deficiencies. However, vigilance must be maintained, particularly regarding bone and neurological risks.</p>","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Kachmar, Thomas H Shin, Jerry T Dang, Vance L Albaugh
{"title":"Comment on: towards a better mouse model of vertical sleeve gastrectomy.","authors":"Michael Kachmar, Thomas H Shin, Jerry T Dang, Vance L Albaugh","doi":"10.1016/j.soard.2025.08.019","DOIUrl":"https://doi.org/10.1016/j.soard.2025.08.019","url":null,"abstract":"","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Moving beyond risk factors - a deeper look into weight regain after sleeve gastrectomy.","authors":"Dimitrios I Athanasiadis","doi":"10.1016/j.soard.2025.08.021","DOIUrl":"https://doi.org/10.1016/j.soard.2025.08.021","url":null,"abstract":"","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: efficacy and safety comparison of single anastomosis sleeve ileal bypass versus one anastomosis gastric bypass: a systematic review and meta-analysis.","authors":"Marius Nedelcu, Ramon Vilallonga","doi":"10.1016/j.soard.2025.08.020","DOIUrl":"https://doi.org/10.1016/j.soard.2025.08.020","url":null,"abstract":"","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary on: Challenges in diagnosing gestational diabetes after Roux-en-Y gastric bypass: a comparative analysis of OGTT, SMBG, and CGM.","authors":"Florina Corpodean","doi":"10.1016/j.soard.2025.04.466","DOIUrl":"10.1016/j.soard.2025.04.466","url":null,"abstract":"","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":"e25-e26"},"PeriodicalIF":3.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas Inge, Justin Ryder, Marc Michalsky, Mark Wulkan, Stephanie Walsh
{"title":"Adolescent metabolic and bariatric surgery in 2025: evidence, urgency, and a call to action.","authors":"Thomas Inge, Justin Ryder, Marc Michalsky, Mark Wulkan, Stephanie Walsh","doi":"10.1016/j.soard.2025.06.009","DOIUrl":"10.1016/j.soard.2025.06.009","url":null,"abstract":"","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":"1084-1086"},"PeriodicalIF":3.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144593293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Julie-Ann Lloyd, Elizabeth Wall-Wieler, Yuki Liu, Feibi Zheng, Teresa LaMasters
{"title":"Unveiling the cost-effectiveness of bariatric surgery: insights from a matched cohort study.","authors":"S Julie-Ann Lloyd, Elizabeth Wall-Wieler, Yuki Liu, Feibi Zheng, Teresa LaMasters","doi":"10.1016/j.soard.2025.04.004","DOIUrl":"10.1016/j.soard.2025.04.004","url":null,"abstract":"<p><strong>Background: </strong>Obesity is a global health problem with alarming rates of morbidity and mortality. Although bariatric surgery is a proven safe and effective treatment for obesity, only a small fraction of eligible patients utilizes it.</p><p><strong>Objectives: </strong>Assess the economic impact of bariatric surgery costs within 2 years of the index date and identify factors associated with cost differences.</p><p><strong>Setting: </strong>U.S. national employer-based retrospective claims database.</p><p><strong>Methods: </strong>Adults with obesity (body mass index [BMI] ≥ 35 kilograms per square meter) were identified in the Merative claims database. Individuals who had a bariatric procedure between January 2017 and December 2019, inclusive, were matched 1:1 with nonsurgical patients, based on age, BMI, sex, comorbidities, and health care costs in the year before the index date. Total and clinical care-specific costs were compared in the 2 years after the index date (excluding the cost of surgery).</p><p><strong>Results: </strong>The study included 9432 surgical patients and 9432 well-matched controls. In the 2 years after the index date, follow-up was complete, and total health care costs were $5677 lower among surgical patients (P < .01). In 29 of 35 characteristics examined, health care costs were significantly reduced after surgery. The largest savings were noted among patients with type 2 diabetes ($15,270), steatohepatitis ($11,648), or ages 50-65 years ($11,105).</p><p><strong>Conclusions: </strong>Bariatric surgery is associated with an average 22.6% reduction in health care costs within 2 years postindex date. Differences in health care costs varied substantially by baseline demographics, health conditions, and health care usage, highlighting surgery's economic and clinical benefits.</p>","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":"987-995"},"PeriodicalIF":3.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michelle Chang, Chiu-Hsieh Hsu, Diaa Soliman, Iman Ghaderi
{"title":"The impact of frailty on serious complications after bariatric surgery: a comparison between robotic and laparoscopic approach.","authors":"Michelle Chang, Chiu-Hsieh Hsu, Diaa Soliman, Iman Ghaderi","doi":"10.1016/j.soard.2025.04.471","DOIUrl":"10.1016/j.soard.2025.04.471","url":null,"abstract":"<p><strong>Background: </strong>Frailty is a state of reduced physiologic capacity, and our group has created a bariatric frailty index using 9 variables from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database. We found that frailty scores had weakly positive correlations with increasing age and body mass index in bariatric patients.</p><p><strong>Objective: </strong>To examine the effect of frailty and pre-frailty on Clavien-Dindo (CD) ≥III grade complications after bariatric surgery for all adults as well as outcomes of surgical approach using the MBSAQIP database (2016-2019).</p><p><strong>Setting: </strong>Data pooled from American Society for Bariatric Surgery-accredited bariatric surgery centers, United States.</p><p><strong>Methods: </strong>All adult patients were included. Fourteen variables of the Canadian Study of Health and Aging Frailty Index were mapped onto 9 variables of MBSAQIP to derive a bariatric frailty score (0-9) which were classified as Not frail (0), pre-frail (1-2), and frail (≥3). Logistic regression was performed to evaluate the effects of frailty on CD ≥III grade complications.</p><p><strong>Results: </strong>Most patients undergoing bariatric surgery were pre-frail (56% versus not frail 33.6% vs frail 10.3%). There was a positive association between greater frailty scores and a greater frequency of CD ≥III grade complications in both laparoscopic and robotic cohorts. Regardless of surgical approach or operation, patients who were classified as pre-frail and frail had greater frequency of serious complications compared with patients classified as not frail.</p><p><strong>Conclusions: </strong>Using a bariatric frailty score to identify patients who are pre-frail and frail may assist with prehabilitation before bariatric surgery and assist with decision-making for surgical approach.</p>","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":"1018-1024"},"PeriodicalIF":3.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inti Pedroso, Shreyas V Kumbhare, Shaneeta Johnson, Karthik M Muthukumar, Santosh K Saravanan, Carmel Irudayanathan, Garima Sharma, Lawrence Tabone, Ranjan Sinha, Daniel E Almonacid, Nova Szoka
{"title":"Microbiome and genetic predictors of weight loss 12 months postsleeve gastrectomy: insights from a pilot retrospective cohort study.","authors":"Inti Pedroso, Shreyas V Kumbhare, Shaneeta Johnson, Karthik M Muthukumar, Santosh K Saravanan, Carmel Irudayanathan, Garima Sharma, Lawrence Tabone, Ranjan Sinha, Daniel E Almonacid, Nova Szoka","doi":"10.1016/j.soard.2025.05.008","DOIUrl":"10.1016/j.soard.2025.05.008","url":null,"abstract":"<p><strong>Background: </strong>Gut microbiome and genetic biomarkers are increasingly guiding obesity treatment. Bariatric surgery leads to shifts in gut microbial composition and function, while genome-wide association studies reveal genetic underpinnings of polygenic obesity, informing risk, therapeutic outcomes, and nutrigenomics-based interventions.</p><p><strong>Objectives: </strong>This pilot study aimed to identify gut microbiome and genetic biomarkers associated with weight loss 12 months after sleeve gastrectomy (SG).</p><p><strong>Setting: </strong>Single academic institution university clinic.</p><p><strong>Methods: </strong>Sixty-seven patients 12 months post-SG were enrolled: 34 had successful excess weight loss (EWL ≥50%), while 33 had unsuccessful EWL (EWL <50%). Microbiome and genetic profiles were collected and analyzed using ANOVA and regression methods.</p><p><strong>Results: </strong>The genus Akkermansia was significantly associated with EWL (P = 9.9 × 10<sup>-6</sup>). Several microbial pathways, including propionate synthesis and menaquinone (vitamin K2) production, showed nominally significant (P < .05) associations with greater weight loss. No differences emerged in the Firmicutes/Bacteroidetes ratio. Genetic analyses revealed significant correlations between EWL and polygenic scores for dietary needs and metabolic responses, including distinct vitamin D and K requirements, as well as higher LDL cholesterol levels and predisposition for major depression.</p><p><strong>Conclusions: </strong>These findings suggest that both the gut microbiome and genetics may modulate weight loss following bariatric surgery. Integrating microbiome and genetic profiling into bariatric care pathways could enhance personalized obesity treatment. While this pilot, exploratory, and proof-of-concept study has limitations, it supports prior work linking gut microbial pathways to weight loss and suggests new associations. Follow-up studies are warranted to validate these results and further inform precision obesity interventions.</p>","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":"1035-1041"},"PeriodicalIF":3.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144328277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John Cord Helmken, Noelle Luzzi, Dawn Blackhurst, Jacqueline Grace Wallenborn, John D Scott
{"title":"Effect of food environment on weight loss after bariatric surgery.","authors":"John Cord Helmken, Noelle Luzzi, Dawn Blackhurst, Jacqueline Grace Wallenborn, John D Scott","doi":"10.1016/j.soard.2025.04.469","DOIUrl":"10.1016/j.soard.2025.04.469","url":null,"abstract":"<p><strong>Background: </strong>The impact of food environment on weight loss after Roux-en-Y gastric bypass and sleeve gastrectomy in South Carolina is not well studied. Specifically, there is a lack of evidence in the Upstate region of South Carolina regarding the efficacy of weight loss surgery in patients who live in a poor food environment.</p><p><strong>Objectives: </strong>Assess the relationship between food environment after bariatric surgery.</p><p><strong>Setting: </strong>South Carolina, USA.</p><p><strong>Methods: </strong>Our study is a single-center, retrospective review of 134 postbariatric surgery patients. We determined patients' food environments using the Center for Disease Control modified retail food environment index (mRFEI) and the South Carolina Department of Health and Environmental Control food desert map. We assessed weight loss using percent of total body weight loss (TBWL%).</p><p><strong>Results: </strong>We found no linear correlations between weight loss and food environment in bivariate analyses at 6 months (r = -.121; P = .165), 13 months (r = -.109; P = .275), 18 months (r = -.124; P = .326), or 36 months (r = -.331; P = .106) after bariatric surgery. At 24 months, there was a low negative correlation between weight loss and food environment (r = -.302; P = .041). In repeated measures multivariate analysis, adjusting for age, sex, race, payor status, and type of surgery, we found no statistically significant association between mRFEI and TBWL% (P = .214).</p><p><strong>Conclusions: </strong>Our data suggest there is no significant association between weight loss after bariatric surgery and living in an area with poor access to healthy food retailers. This study supports bariatric surgery as an effective method for weight loss regardless of patients' food environment.</p>","PeriodicalId":94216,"journal":{"name":"Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery","volume":" ","pages":"1012-1017"},"PeriodicalIF":3.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}