Skinmed Pub Date : 2024-08-02 eCollection Date: 2024-01-01

Laurel McEwen, Corinne Dechelette

{"title":"The Skin is a Virtual Reality: A Multicultural, -Exploratory, and Anthropologic Study.","authors":"Laurel McEwen, Corinne Dechelette","doi":"","DOIUrl":"","url":null,"abstract":"No other organ in the human body has as many functions as the skin-biologic, cultural, social, and psychologic. The skin is the first attribute we notice, and it is the basis of our first impressions. It provides information about our state of health, our moods, our age, and sometimes our cultural background. Above all, the skin is an organ like the heart or the lungs. The objective of this exploratory anthropologic study was to shed light on the people's global perception of the skin. More precisely, we wanted to explore how people think about their skin and whether they think of it in terms of its biologic role and importance as their body's largest organ. We wanted to know how aware they are about the skin's anatomy, functionality, and the pathologies that most concern them. Do people consider their skin merely as an envelope of beauty or as something more? To find out, we conducted a prospective anthropologic study of a random sampling of multicultural individuals in and around Paris, France. Participants were given a questionnaire with six semi-structured questions and one open-ended question about their per-ceptions and attitudes of their skin. Responses were analyzed on the basis of word groupings within the six major categories of considerations represented by the available literature on the skin in both French and English. The results of this study demonstrated the mutable nature of people's perception of their skin. Rather than remaining with one fixed vision, their thoughts about their skin changed in conjunction with their age, life experiences, and lifestyle in accordance with wider societal and environmental realities. In addition, their perspectives tended to go beyond cultural groupings, displaying a certain homogeneity of vision across demographic categories. As such, we concluded that the skin is a form of virtual reality that is constructed and reconstructed as one moves through life in the society.","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

H Syndrome: Three New Cases from Morocco. H 综合征：摩洛哥的三个新病例

Skinmed Pub Date : 2024-08-02 eCollection Date: 2024-01-01

Chaimaa Fikri, Maryam Aboudouraib, Imane Ait Sab, Said Amal, Ouafa Hocar

{"title":"H Syndrome: Three New Cases from Morocco.","authors":"Chaimaa Fikri, Maryam Aboudouraib, Imane Ait Sab, Said Amal, Ouafa Hocar","doi":"","DOIUrl":"","url":null,"abstract":"A 19-year-old girl presented with symmetric and bilateral hyperpigmentation, an indurated lesion that initially appeared on the axillary fold at the age of 14, which then extended to the lower back, anterior aspect of both thighs, and popliteal fold. No hypertrichosis was observed (Figure 1).The patient was the youngest of the four children, born from the first-degree consanguineous marriage. She was born at full term and weighed 2,420 g at birth. No similar patient was present in the family. The patient experienced delayed motor acquisition and stature growth (3rd percentile) until the age of 4. Right hypoacusis was diagnosed at the age of 6. She developed hallux valgus, flexion contracture of the fin-gers and toes, barrel deformity of the anterior thorax, and recurrent fever. The laboratory tests, including fasting blood glucose, -triglycerides, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) were normal. Her abdominal, pelvic, and transthoracic ultrasound scans were normal, with no hepatosplenomegaly, lymphadenopathy, or cardiac abnormalities. Histologic analysis demonstrated patchy acanthosis of the epidermis, with orthokeratotic hyperkeratosis. Keratinocyte hyperpigmentation and spongiosis at certain areas were observed with moder-ate inflammation because of the infiltration of lymphocytes, histiocytes, and plasma cells. Immunohistochemical analysis showed macrosialin (CD68+) and common gamma chain (γc) CD132. Germline mutations in the SLC29A3 gene were not analyzed. The patient was prescribed dermocorticoids with depigmentation therapy, which demonstrated moderate clinical evolution.","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Evaluation of the Efficacy of Itch-Relief Moisturizers Containing Maltotetraose for Dry, Itchy, and Sensitive Skin. 含麦芽四糖的止痒保湿霜对干燥、瘙痒和敏感皮肤的功效临床评估

Skinmed Pub Date : 2024-08-02 eCollection Date: 2024-01-01

Eri Ichikawa, Akinori Inoue, Kenichi Matsuzaki, Sumi Kaneda, Atsushi Naito, Mihoko Yokoyama

{"title":"Clinical Evaluation of the Efficacy of Itch-Relief Moisturizers Containing Maltotetraose for Dry, Itchy, and Sensitive Skin.","authors":"Eri Ichikawa, Akinori Inoue, Kenichi Matsuzaki, Sumi Kaneda, Atsushi Naito, Mihoko Yokoyama","doi":"","DOIUrl":"","url":null,"abstract":"Itching is a prominent clinical manifestation of sensitive skin; it reduces cutaneous barrier function, mainly caused by dryness. Scratching to relieve itching destroys the skin barrier, thus forming the itch-scratch cycle that results in additional disruption of skin barrier and chronic itching. Treatment involves alleviation from itching for sensitive skin. Recently, substance P (11-amino acid neuropeptide of the tachykinin family) and neurokinin 1 receptor (NK1R) have been considered to provide a key pathway to treat chronic itching. A single-center, open-label study was conducted comprising subjects with dry, itchy, and sensitive skin to evaluate the efficacy of two types of itch-relief moisturizers, mist and lotion, containing maltotetraose (MTO). In all, 35 subjects used mist containing MTO, resulting in significant improvement in itch score from 1 minute to 2 hours following single application. On the other hand, 34 subjects applied lotion containing MTO for 1 week, resulting in significant improvement in itch score, skin hydration, and clinical scores of erythema/redness and dryness; however, in both cases, improve-ment was not observed in the measurement of transepidermal water loss (TEWL). It was concluded that two types of itch-relief moisturizers containing MTO were effective for dry, itchy, and sensitive skin.","PeriodicalId":94206,"journal":{"name":"Skinmed","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Atlas of the Human Nail. 人类指甲图谱