Puerto Rico health sciences journal最新文献_第3页

Physical Activity in Puerto Rico: Recommendations for Research, Surveillance, and Policy Development. 波多黎各的体育活动：研究、监测和政策制定的建议。

Puerto Rico health sciences journal Pub Date : 2025-03-01

Raúl D Gierbolini-Rivera, Alexandre A De Paula da Silva, Milena F Silva, Ana L Favarão Leão, Farah A Ramirez-Marrero

{"title":"Physical Activity in Puerto Rico: Recommendations for Research, Surveillance, and Policy Development.","authors":"Raúl D Gierbolini-Rivera, Alexandre A De Paula da Silva, Milena F Silva, Ana L Favarão Leão, Farah A Ramirez-Marrero","doi":"","DOIUrl":"","url":null,"abstract":"Objective: The objectives of this report were to 1) describe the 2015 and 2020 physical activity (PA) Country Cards of Puerto Rico (PR), including data beyond the 2020 Country Card, and 2) propose recommendations for promoting PA research, surveillance, and policy development.Methods: A comparison of the 2015 and 2020 data from the PR Country Cards provided by the Global Observatory for Physical Activity (GoPA!) was conducted. Country Card data were collected from the World Bank, the United Nations, PubMed, and the Behavioral Risk Factor Surveillance Survey (BRFSS). This ensured that data indicators were standardized for global comparability. Local representatives facilitated data collection through a collaborative review process with GoPA! Country Card data included demographic characteristics, mortality rates, PA prevalence, surveillance data, policy, and research indicators.Results: In 2015, the BRFSS data indicated a PA prevalence of 34% in PR, decreasing to 20% in 2020. No data on inactivity-related mortality or a national standalone plan focused on PA was available. From 2015 to 2020, research output in PR increased slightly, improving its global ranking from the 61st to the 58th position.Conclusion: The PR Country Card is a tool to raise awareness and identify surveillance, research, and policy gaps. Recommendations include establishing a dedicated PR health monitoring system, integrating PA into PR national public health plans, and establishing an interinstitutional coalition for PA research (in PR). Multi-sector efforts from policymakers, researchers, and stakeholders are essential for meaningful progress in improving PA levels and public health in PR.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"63-68"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143757001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of the Pandemic on Food Security on Households with Children with Special Health Care Needs in Puerto Rico: A Survey Study. 大流行病对波多黎各有特殊保健需要的儿童家庭粮食安全的影响：一项调查研究。

Puerto Rico health sciences journal Pub Date : 2025-03-01

Ana L Mulero-Portela, Carmen L Colón-Santaella, Winna Rivera

{"title":"Impact of the Pandemic on Food Security on Households with Children with Special Health Care Needs in Puerto Rico: A Survey Study.","authors":"Ana L Mulero-Portela, Carmen L Colón-Santaella, Winna Rivera","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This study examined how the COVID-19 pandemic contributed to food insecurity in households in Puerto Rico with children with disabilities, compared to households with children without disabilities.Methods: The present study used a 2-group, cross-sectional design. Participants were interviewed once to describe experiences of food insecurity during the 12 months before the COVID-19 pandemic and again during the pandemic lockdown. In addition, demographic characteristics and mental and physical health were assessed.Results: Before the COVID-19 pandemic, food insecurity in Puerto Rico was significantly higher in households with children with disabilities (n = 48) than in households with children without disabilities (n = 49) (P < .001). During the COVID-19 pandemic, this difference remained (P = .029). Food insecurity was higher before the pandemic among children in households with children with disabilities (odds ratio [OR]: 3.62; 95% CI:1.19-11.05), and in households overall (OR: 4.72; 95% CI: 1.83 12.14), when assessing adults and children in the same household. This was also true during the pandemic for households overall (OR: 2.54; 95% CI: 1.09-5.96), but to a lesser degree. Food insecurity was not statistically significant in children during the pandemic (OR: 2.56; 95% CI: 0.97-6.74). In both types of households, physical and mental health scores were more than 1 standard deviation below the United States mean.Conclusion: Both types of households experienced food insecurity during the pandemic. No relationship between food insecurity, disability, and health status was observed in the study sample. All the participants reported low physical and mental health.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between Tumor Ploidy and Overall Survival in Pediatric Neuroblastoma. 儿童神经母细胞瘤肿瘤倍性与总生存率的关系。

Puerto Rico health sciences journal Pub Date : 2025-03-01

Tyrel R Porter, Emir Rinaldi-Pérez, Marcel Grau-Rodríguez, Lilia Y Kucheryavykh

{"title":"Associations between Tumor Ploidy and Overall Survival in Pediatric Neuroblastoma.","authors":"Tyrel R Porter, Emir Rinaldi-Pérez, Marcel Grau-Rodríguez, Lilia Y Kucheryavykh","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the relationships between pediatric neuroblastoma outcomes, tumor ploidy, and ethnicity, focusing on disparities in overall survival (OS) while also accounting for race and ethnicity.Methods: Clinical and tumor ploidy data for 63 Hispanic White, 561 non-Hispanic White, and 86 non-Hispanic Black patients were obtained from cBioPortal for Cancer Genomics (TARGET [Therapeutically Applicable Research to Generate Effective Treatments], 2018). Kaplan Meier survival curves were analyzed using log-rank and Gehan-Breslow Wilcoxon tests. Hazard ratios (HR) with 95% CIs were calculated using the Mantel-Haenszel method. Associations between ethnicity and tumor ploidy were assessed using the chi-square test.Results: Significant differences in overall survival (OS) were observed between White patients who self-identified as Hispanic and those who identified as non Hispanic, with Hispanic patients exhibiting worse outcomes. (P = .0076, HR = 1.907, 95% CI: 1.187-3.062). Median survival for Hispanic patients was 94 months but was undefined for non-Hispanic patients. Diploid tumors were associated with worse outcomes than hyperdiploid tumors were (P < .0001, HR = 2.291, 95% CI: 1.689-3.109). The chi square test revealed a significant association between ethnicity and tumor ploidy (χ2 = 4.220, P = .0400), with non-Hispanic patients having a higher proportion of hyperdiploid tumors (66.99%) than Hispanic patients (53.97%).Conclusion: Hispanic White patients with neuroblastoma had lower OS than did non-Hispanic White patients, partly due to the former having a higher proportion of diploid tumors. These findings highlight the importance of considering ethnicity and tumor ploidy in risk stratification and treatment strategies.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"69-73"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mental Health and Access to Resources in a Schoolteacher Population Impacted by Earthquakes and the Pandemic in Puerto Rico. 波多黎各受地震和流行病影响的教师群体的心理健康和资源获取。

Puerto Rico health sciences journal Pub Date : 2025-03-01

Yanice Vanessa Méndez-Fernández, Alvin Tran, Mario Flores-Torres, Elvin Estrada-García, Jailene Marie Resto

{"title":"Mental Health and Access to Resources in a Schoolteacher Population Impacted by Earthquakes and the Pandemic in Puerto Rico.","authors":"Yanice Vanessa Méndez-Fernández, Alvin Tran, Mario Flores-Torres, Elvin Estrada-García, Jailene Marie Resto","doi":"","DOIUrl":"","url":null,"abstract":"Objective: A study was conducted to evaluate the mental health status and access to essential resources in a sample of schoolteachers impacted by earthquakes and the COVID-19 pandemic in Southwestern Puerto Rico.Methods: From November 2020 through September 2021, an online survey was administered to schoolteachers working in municipalities listed in the Federal Emergency Management Agency earthquake disaster declaration. The prevalences of post-traumatic stress disorder (PTSD), anxiety, and depression were calculated based on scores from the PTSD Checklist for DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) (PCL-5), the Generalized Anxiety Disorder 7-item (GAD-7) scale, and the Center for Epidemiologic Studies-Depression (CES-D-7) scale, respectively.Results: Most of the teachers in the sample (N = 58) reported serving students of low socioeconomic status (93.1%). Forty-eight percent (48.3%) reported having trouble making necessary home repairs, and 32.8%, accessing medical care. Twenty-one percent (20.7%) of the teachers met the clinical cutoff for PTSD, and 12.1% scored within the range of severe anxiety. Twenty-four percent (24.1%) of the teachers obtained scores indicative of depression.Conclusion: The survey findings highlight the need to provide mental health services to schoolteachers in the aftermath of a natural disaster in Puerto Rico.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"46-53"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coping Styles of Patients Hospitalized in an Intermediate Trauma Unit. 中级创伤科住院病人的应对方式

Puerto Rico health sciences journal Pub Date : 2025-03-01

Ana C Sala, Lydia Temoshock, Milagros Figueroa, Omar García, Lourdes Guerrios, Pablo Rodríguez, Karen G Martínez

{"title":"Coping Styles of Patients Hospitalized in an Intermediate Trauma Unit.","authors":"Ana C Sala, Lydia Temoshock, Milagros Figueroa, Omar García, Lourdes Guerrios, Pablo Rodríguez, Karen G Martínez","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Effective coping with the physical and mental changes experienced after traumatic injury decreases stress, reduces complications, and promotes healing. Although there are many studies of coping in medical patients, there is little research concerning the coping styles of patients hospitalized in trauma units. This study aimed to achieve two main objectives: (1) adapt the Vignette Similarity Rating Method for implementation in a Puerto Rican trauma unit, and (2) describe the coping styles of patients admitted to the unit, exploring their association with sociodemographic, clinical, and situational factors.Methods: Patients hospitalized in a trauma unit were recruited. Nine patients participated in the adaptation process (33% women, 67% men; mean age 37.75), while in the coping assessment phase 43 patients were included (41.9% women, 58.1% men; mean age 39.5). The culturally and contextually adapted Vignette Similarity Rating Method was employed to depict and evaluate coping strategies. Associations between two adaptive coping styles, three less adaptive coping styles, sociodemographic and clinical characteristics of the participants, and length of hospital stay were determined.Results: Participants reported a higher level of similarity with adaptive coping vignettes (median=18.0), followed by active coping vignettes (median=14.0). Individuals living with diabetes (p = .006) and those experiencing longer hospital stays (p = .018) reported a greater similarity to less effective Type A coping vignettes.Conclusion: These findings emphasize the importance of considering the effectiveness of coping styles within specific contexts and to developing interventions that promote adaptive coping strategies, especially for patients facing prolonged hospitalization.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"32-38"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fenoldopam use during Cardiopulmonary Bypass and Postoperative Rates of Acute Kidney Injury. 体外循环期间非诺多泮的使用和术后急性肾损伤的发生率。

Puerto Rico health sciences journal Pub Date : 2025-03-01

Brian Oyler, Kevin Dao, Nayda Parisio-Poldiak, Russell F Stahl

{"title":"Fenoldopam use during Cardiopulmonary Bypass and Postoperative Rates of Acute Kidney Injury.","authors":"Brian Oyler, Kevin Dao, Nayda Parisio-Poldiak, Russell F Stahl","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Acute kidney injury (AKI) is a complication following heart surgery that is associated with increased morbidity and mortality. Fenoldopam is a dopaminergic receptor agonist that has been successful in the prevention of cardiac surgery-associated AKI. We hypothesized that fenoldopam started preoperatively would reduce the risk of AKI in patients with chronic kidney disease (CKD), stage 3 or higher.Methods: We conducted a retrospective study of adult patients admitted from 2015 to 2019 for cardiac surgery requiring cardiopulmonary bypass (CPB). Fenoldopam was started in the operating room 1 to 2 hours before the procedure and continued for up to 16 hours post-CPB at a rate of 0.3 mcg/kg/min. The primary outcome was the incidence of postoperative AKI with or without fenoldopam.Discussion: A total of 203 patients with CKD stage 3 or higher were examined in this study, 35.5% of whom received fenoldopam. Of the patients who received fenoldopam, 41.67% developed AKI compared to 38.17% of those without fenoldopam. Being female had a small protective effect against AKI (OR 0.233, CI 0.108-0.502), as did having an adequate hematocrit level prior to surgery (OR 0.921, CI 0.871-0.974). Analysis revealed that a hematocrit level of 37.18% indicated anemia in the study population.Conclusions: While the administration of fenoldopam prior to CPB in patients with CKD stage 3 or higher did not significantly reduce AKI after cardiac surgery or significantly reduce length of stay, possible renal protective properties were identified. Being female and having an adequate preoperative hematocrit level were identified as possible investigative points for future studies.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"3-8"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inpatient Pediatric Trauma Epidemiology at the Puerto Rico Trauma Hospital From 2015 Through 2019. 波多黎各创伤医院2015年至2019年住院儿童创伤流行病学研究。

Puerto Rico health sciences journal Pub Date : 2025-03-01

Pedro E Ruiz-Medina, Ediel O Ramos-Meléndez, Mariely Nieves-Plaza, Laura Ramírez-Martínez, Adrianna Rivera-Delgado, Lourdes Guerrios-Rivera, Pablo Rodríguez-Ortiz

{"title":"Inpatient Pediatric Trauma Epidemiology at the Puerto Rico Trauma Hospital From 2015 Through 2019.","authors":"Pedro E Ruiz-Medina, Ediel O Ramos-Meléndez, Mariely Nieves-Plaza, Laura Ramírez-Martínez, Adrianna Rivera-Delgado, Lourdes Guerrios-Rivera, Pablo Rodríguez-Ortiz","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Despite the high volume of admissions to the Puerto Rico Trauma Hospital (PRTH), there is no evidence of any recent trends related to pediatric trauma. Therefore, we aimed to update, describe, and compare the epidemiology of the pediatric (≤21 years) trauma population in PR according to age group (≤15 years and 16-21 years).Methods: This was a retrospective cohort study of 853 PRTH pediatric admissions from January 2015 through June 2019. A comparison between age groups was done using Pearson's chi-square test. The association between age and study outcomes was evaluated with multivariate analyses.Results: Of the admissions, 220 (25.8%) were patients aged 15 years and younger and 633 (74.2%) were patients aged 16 to 21 years; the percentage of males was higher in the latter group (65.5% vs. 79.0%; P < .01). Motor vehicle accidents were the primary injury mechanism. Major trauma (Injury Severity Score >15) incidence was higher in the under 15 group (40.8% vs. 24.5%; P < .01). After adjusting for confounders, 16- to 21-year-old trauma patients were less likely to be admitted to the intensive care unit (ICU) than were their younger counterparts but were more prone to having longer ICU and hospital stays. However, age was not associated with the need for mechanical ventilation (MV), days of MV, or in-hospital mortality.Conclusion: Understanding the specific characteristics of our pediatric patient population can help us guide treatment and elucidate these patients' needs to improve their outcomes.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between Stressors after Hurricanes Irma and María and Psychological Distress in Patients with Active Breast and Colorectal Cancer Treatment. Irma飓风和María后压力源与积极治疗乳腺癌和结直肠癌患者心理困扰的关系

Puerto Rico health sciences journal Pub Date : 2025-03-01

Hérmilis Berríos, Vivian Colón-López, Claudia Amaya-Ardila, Karen Ortiz-Ortiz, Marievelisse Soto, Cynthia M Pérez

{"title":"Association between Stressors after Hurricanes Irma and María and Psychological Distress in Patients with Active Breast and Colorectal Cancer Treatment.","authors":"Hérmilis Berríos, Vivian Colón-López, Claudia Amaya-Ardila, Karen Ortiz-Ortiz, Marievelisse Soto, Cynthia M Pérez","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This study aimed to explore the stressors faced by breast and colorectal cancer patients following Hurricanes Irma and María in Puerto Rico and to evaluate their association with post-hurricane psychological distress.Methods: A telephone-based survey was conducted with 241 cancer patients (140 with breast cancer and 101 with colorectal cancer) aged ≥40 years, diagnosed at least six months before September 2017, and undergoing treatment at the time of the hurricanes. Data on traumatic stressors (e.g., experiences directly related to life-threatening situations), non-traumatic stressors (e.g., difficulties accessing basic needs), and psychological distress (measured using the Kessler 6-item Psychological Distress Scale) were collected. Poisson regression estimated the prevalence ratio (PR, 95% CI) for psychological distress according to hurricane-related stressors, adjusting for age, cancer type, pre-hurricane preparedness, and social support.Results: Nearly 25% of participants faced traumatic stressors, 57.5% were exposed to nontraumatic stressors, and 45.6% presented elevated psychological distress. Those who faced traumatic and nontraumatic stressors demonstrated elevated psychological distress compared to their counterparts (PR=1.73, 95% CI=1.36, 2.20; PR=1.69, 95% CI=1.21, 2.35; respectively) after adjusting for age, cancer type, pre-hurricane preparedness, and social support.Conclusion: Breast and colorectal cancer patients experienced heightened psychological distress due to exposure to various hurricane-related stressors. It is crucial to prioritize an action plan that addresses disaster preparedness, response, and the mental well-being of vulnerable populations like cancer patients to enhance their overall health and resilience.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"44 1","pages":"18-24"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12135026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are Patients who are Diagnosed with Hypertension or Diabetes more likely to Receive the COVID-19 Booster? Data from PR-CEAL's Community Survey Tool. 确诊为高血压或糖尿病的患者是否更有可能接受 COVID-19 增效剂？数据来自 PR-CEAL 的社区调查工具。

Puerto Rico health sciences journal Pub Date : 2024-12-01

Valeria V Vidal-Vega, Hérmilis Berríos-Ortiz, Karelys Canales-Birriel, Vivian Colón-López

{"title":"Are Patients who are Diagnosed with Hypertension or Diabetes more likely to Receive the COVID-19 Booster? Data from PR-CEAL's Community Survey Tool.","authors":"Valeria V Vidal-Vega, Hérmilis Berríos-Ortiz, Karelys Canales-Birriel, Vivian Colón-López","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Evaluate the relationship between diabetes and hypertension and COVID-19 booster uptake.Methods: Members of the Community Outreach Group of the Puerto Rico Community Engagement Alliance Against COVID-19 Disparities (PR-CEAL) administered a survey at 229 community events between November 2021 and May 2023. Information on 2,145 participants' sociodemographic information and chronic disease diagnoses was gathered. Characteristics distributions were described using frequency and percentages. The associations between demographic factors and booster uptake were assessed using chi-squared analysis for categorical variables. Multivariate logistic regression models were used to estimate odds ratios (OR) with 95% confidence intervals (CI), adjusting for age, sex, education, and medical insurance, to investigate the relationship between hypertension and diabetes and booster uptake.Results: Participants' mean age was 43.8 years. Most (80%) were women and had received a COVID-19 booster (84%). A high prevalence of hypertension (43%) and diabetes (33%) was observed in this study sample. Bivariate analyses showed a statistically significant association between receiving the booster and having hypertension or diabetes (p<0.05). Adjusted multivariate analysis showed that participants with diabetes were 3% more likely to have the booster than those without diabetes (OR=1.03, 95% CI: (1.01-1.05), p<0.05). No significant association was found between hypertension and booster uptake in the adjusted multivariate analysis (OR=1.01, 95% CI: (0.99-1.03), p=0.13).Conclusion: Insights from this study can inform future vaccination campaigns through improved awareness and prevention strategies by targeting vulnerable populations in Puerto Rico.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"43 4","pages":"226-229"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breast and Colorectal Cancers in Women: a Meta-Analysis Driven by BioOptimatics. 女性乳腺癌和结直肠癌：由生物优化驱动的荟萃分析。

Puerto Rico health sciences journal Pub Date : 2024-12-01

Xavier J Aguilar-García, Alibeth E Luna-Alvear, Isis Narváez-Bandera, Deiver Suárez-Gómez, Clara E Isaza, Mauricio Cabrera-Rios

{"title":"Breast and Colorectal Cancers in Women: a Meta-Analysis Driven by BioOptimatics.","authors":"Xavier J Aguilar-García, Alibeth E Luna-Alvear, Isis Narváez-Bandera, Deiver Suárez-Gómez, Clara E Isaza, Mauricio Cabrera-Rios","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This meta-analysis explored genes in common between breast cancer (BC) and colorectal cancer (CRC) in women. Breast cancer and CRC are causes of significant morbidity and mortality in women worldwide. Research has shown that women are underrepresented in clinical trials, especially in oncology; studying sex differences in cancer addresses this lack.Methods: Ten GEO (Gene Expression Omnibus) dataset (5 BC and 5 CRC) were used to identify genes in common. Correlated networks were constructed and analyzed using BioOptimatics methodologies, including multiple criteria optimization and minimum spanning tree.Results: Eighteen differentially expressed genes were identified, with such core genes as B3GNT3, CALU, CD46, DCN, DLX4, and others showing high frequencies. The study also identified 289 diseases related to core genes, further narrowed down to 37, including BC and CRC. Direct associations with BC and CRC were found for 5 genes, while 7 were linked to other cancer types.Conclusion: The results of this study underscore the importance of sex differences in cancer biology and indicate that this methodology, BioOptimatics, can help in the discovery of new pathways and biomarkers for BC and CRC in women.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":"43 4","pages":"186-195"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0