Puerto Rico health sciences journal最新文献_第3页

Ophthalmologic Findings in a Premature Infant leading to a Zika Diagnosis during the COVID-19 Pandemic: A Case Report. 在 COVID-19 大流行期间，一名早产儿的眼科发现导致寨卡诊断：病例报告。

Puerto Rico health sciences journal Pub Date : 2024-03-01

Jessica M Rosario-Falero, Gabriella P Morantes-Betancourt, Norma Claudio, Raúl Pérez, Zayhara Reyes-Bou

引用次数: 0

Resilience, Self-Efficacy, and Symptoms of Anxiety and Depression in Older Adults during COVID-19 Confinement. COVID-19禁闭期间老年人的复原力、自我效能以及焦虑和抑郁症状。

Puerto Rico health sciences journal Pub Date : 2024-03-01

David Pérez-Jiménez, José A Maldonado-Martínez, Aida L Jiménez-Torres

{"title":"Resilience, Self-Efficacy, and Symptoms of Anxiety and Depression in Older Adults during COVID-19 Confinement.","authors":"David Pérez-Jiménez, José A Maldonado-Martínez, Aida L Jiménez-Torres","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This study examined the relationship between resilience, self-efficacy, anxiety, and depression to test whether self-efficacy affected anxiety and depression and compared how the participants in different age groups experienced anxiety, as well as the differences in anxiety between employed and unemployed participants.Method: A cross sectional web-based survey study that included adults aged 60 years or older living in Puerto Rico was performed during April and May 2020.Results: A total of 299 older adults completed the online questionnaire (14% men, 83.6% women). Of the total sample, 25.4% reported having moderate to severe symptoms of anxiety, while 20.8% reported having moderate to severe symptoms of depression. Our path analysis model suggested that while self-efficacy did not directly affect anxiety, it had an impact on resilience, thereby reducing anxiety symptoms. The participants who were 71 years old or older had lower anxiety levels than their younger counterparts did. We also confirmed that work might serve as a protective factor against anxiety.Conclusion: Our findings underscore the importance of resilience, self-efficacy, and working later in life to promote well-being and successful aging.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Relationship of Nesfatin-1, Adropin Levels and Claudin-2, Renalase Immunoreactivity with Kidney Function in an Experimental Hypertension Model. 实验性高血压模型中 Nesfatin-1、Adropin 水平和 Claudin-2、肾酶免疫活性与肾功能关系的研究

Puerto Rico health sciences journal Pub Date : 2024-03-01

Muhammed Ali Aydin, Nurettin Aydogdu, Ebru Tastekin, Nihayet Firat, Ozlem Yalcinkaya Yavuz

{"title":"Investigation of the Relationship of Nesfatin-1, Adropin Levels and Claudin-2, Renalase Immunoreactivity with Kidney Function in an Experimental Hypertension Model.","authors":"Muhammed Ali Aydin, Nurettin Aydogdu, Ebru Tastekin, Nihayet Firat, Ozlem Yalcinkaya Yavuz","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Hypertension is one of the cardiovascular diseases that causes the most mortality, and 95% of the causes are unknown. The aim of the study was to examine the possible correlation of nesfatin-1 levels, adropin levels, claudin-2 immunoreactivity (claudin-2 expression in the renal proximal tubule), and renalase immunoreactivity (renalase expression in the renal proximal tubule) with arterial blood pressure, kidney function, and kidney damage.Methods: Adult male Sprague Dawley rats were divided into control and hypertension groups (8 per group). Angiotensin II vehicle was given to the control group and angiotensin II (0.7 mg/kg/day) to the hypertension group, both via an osmotic mini pump for 7 days. The animals blood pressures were measured by tail cuff plethysmography on days 1, 3, 5, and 7. On day 7, 24-hour urine, blood, and tissues were collected from the rats.Results: In the hypertension group compared with the control group, there was an increase in systolic blood pressure levels after day 1. While claudin-2 immunoreactivity was reduced in the kidneys, renalase immunoreactivity was increased. There was a decrease in creatinine clearance and an increase in fractional potassium excretion (P < .05).Conclusion: Our results showed that claudin-2 and renalase are associated with renal glomerular and tubular dysfunction and may play discrete roles in the pathogenesis of hypertension. We believe that these potential roles warrant further investigation.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Corticotomy and Micro-osteoperforation during Canine Retraction: A Split-Mouth Design. 犬牵引过程中皮质切开术与显微骨穿孔术的比较：分口设计

Puerto Rico health sciences journal Pub Date : 2023-12-01

Carina Perez-Cisneros, Augusto R Elías-Boneta, Sona Rivas-Tumanyan, Manuel Rodríguez-Reyes, Mario Polo

{"title":"Comparison of Corticotomy and Micro-osteoperforation during Canine Retraction: A Split-Mouth Design.","authors":"Carina Perez-Cisneros, Augusto R Elías-Boneta, Sona Rivas-Tumanyan, Manuel Rodríguez-Reyes, Mario Polo","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Compare the efficacy of the micro-osteoperforation (MOP) and corticotomy techniques in terms of maxillary canine retraction.Methods: Thirteen patients (5 females, 8 males; mean age, 18.07 ± 6.74 years) with healthy permanent dentition and requiring the extraction of maxillary first premolars were included in a split-mouth randomized clinical trial. Those subjects with previous orthodontic or endodontic treatment of the canines were excluded. At least 3 months post-extraction, MOPs and corticotomies were performed distal to the canines. Mini-screws with closed-coil springs (150 g) were used for the canine retraction. Dental casts were made at baseline (T0) and 3 months post-intervention (T1). Trained and calibrated examiners measured the distances from the canines to the second premolars on both sides. A signed-rank sum test was used to compare the amount of canine retraction achieved in 3 months (T0-T1) on the 2 sides.Results: Retraction (mm) at the incisal level was similar in the corticotomy (3.34 ± 1.01) and MOP patients (2.74 ± 1.10) (P = 0.11); furthermore, there were no differences in the degree of medial retraction between the corticotomy (2.56 ± 0.67) and MOP (2.27 ± 0.82) (P = 0.31) procedures. No adverse events were observed.Conclusion: There were not any clinically or statistically significant differences in retraction between the interventions. At 3 months, a MOP is as effective as a corticotomy in accelerating the rate of tooth movement.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138807483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Novel Case of Legionnaire's Disease after Staying at Home Rentals. 在家租房后患军团病的新病例。

Puerto Rico health sciences journal Pub Date : 2023-12-01

Maria Isabel Hawayek, Alvaro Aranda, Juan Malpica

引用次数: 0

Evaluating Alterations in Breast Cancer Patients after Recovery Via A PET/CT-Assisted Metabolomics Approach. 通过 PET/CT 辅助代谢组学方法评估乳腺癌患者康复后的体征变化

Puerto Rico health sciences journal Pub Date : 2023-12-01

Adem Maman, Onur Senol

{"title":"Evaluating Alterations in Breast Cancer Patients after Recovery Via A PET/CT-Assisted Metabolomics Approach.","authors":"Adem Maman, Onur Senol","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Breast cancer is a mortal disease that causes many deaths, especially in women. Improved therapies could contribute positively to survival rates. Metabolomics is an important tool for monitoring the alterations of several metabolites in clinical cases. This study aimed to develop a metabolomics model to observe (via mass spectroscopy) metabolic alterations in patients who suffered from breast cancer (BC), both before and after their recovery.Materials and methods: Grades 1 and 2 invasive ductal carcinoma patients were evaluated based on their positron emission tomography/computed tomography results. Fourteen patients who had fully recovered from BC were subjected to metabolomics analysis. Plasma samples were extracted and analyzed via quadrupole time-of-flight mass tandem spectroscopy. A chemometrics analysis was performed in order to determine the statistically significant metabolites. All the metabolites were annotated via the mummichog algorithm.Results and discussion: According to the data analysis, glucose, ornithine, phenyalanine, some vitamins, and metabolites in the fatty acid metabolism were statistically altered after recovery of each patient.Conclusion: Untargeted metabolomics studies can be used to understand the etiopathogenesis of breast cancer, finding new biomarkers and alterations of metabolic pathways. After the tumor burden was removed, homeostasis was restored and the concentration of several metabolites began to normalize. This study elucidated the effects of breast cancer at the molecular level.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138808151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Preventive and Therapeutic Oral Health Care: A Case Report of Mucopolysaccharidosis Type IV A in a Pediatric Patient. 全面的口腔预防和治疗护理：小儿黏多醣症Ⅳ型A的病例报告。

Puerto Rico health sciences journal Pub Date : 2023-12-01

Chanchala Hp, Gunica Harjai, Vidya G Doddawad, Manjual S

引用次数: 0

The Role of Sirtuins in Cell Life and their Potential Therapeutic Uses. Sirtuins 在细胞生命中的作用及其潜在治疗用途。

Puerto Rico health sciences journal Pub Date : 2023-12-01

Lyda C Caballero-Méndez, Andrea E García, Luz Natalia Franco-Montoya

引用次数: 0

Investigation of the IL7Rα Gene Polymorphism rs6897932 and the Expression Levels of the CDH1, TTPAL, and FHIT Genes in Patients with Breast Cancer. 乳腺癌患者 IL7Rα 基因多态性 rs6897932 与 CDH1、TTPAL 和 FHIT 基因表达水平的研究

Puerto Rico health sciences journal Pub Date : 2023-12-01

Evrim Suna Arikan-Soylemez, Murat Çilekar, Murat Akici, Çigdem Tokyol, Hatice Arzu Özyürek, Zafer Söylemez, Mustafa Solak

{"title":"Investigation of the IL7Rα Gene Polymorphism rs6897932 and the Expression Levels of the CDH1, TTPAL, and FHIT Genes in Patients with Breast Cancer.","authors":"Evrim Suna Arikan-Soylemez, Murat Çilekar, Murat Akici, Çigdem Tokyol, Hatice Arzu Özyürek, Zafer Söylemez, Mustafa Solak","doi":"","DOIUrl":"","url":null,"abstract":"Objective: The aim of this study was to determine the expression levels of CDH1, FHIT, and TTPAL genes and to determine the genotype and allele frequencies of the IL7Rα gene polymorphism rs6897932 in patients with breast cancer.Methods: The expression levels of genes and the distribution of the IL7Rα gene polymorphism rs6897932 were analyzed by real-time polymerase chain reaction.Results: No differences in genotype ratios or allele frequencies were observed between the 2 groups for the IL7Rα gene polymorphism rs6897932. The frequency of the IL7Rα rs6897932 T risk allele was found to be similar between breast cancer patients and controls. CDH1 messenger RNA (mRNA) levels decreased (0.714-fold and 0.834-fold, respectively), and TTPAL mRNA levels increased (2.675-fold [P < .05] and 1.169-fold, respectively) in tumor tissues and peripheral blood samples. FHIT mRNA levels decreased (0.559-fold) in tumor tissue samples and increased (2.21-fold) in peripheral blood samples.Conclusion: Our results are compatible with those reported in the literature. It can be suggested that the upregulation observed in the TTPAL gene might be a marker for breast cancer. The downregulation of CDH1 and FHIT gene expression has been validated in our study. An increase in the copy numbers of FHIT mRNA in blood samples and a decrease in the tumor samples can also be considered an abnormal condition.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138808154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compliance with Influenza Vaccination and Cervical, Breast, and Colorectal Cancer Screening in a Sample of Women in Puerto Rico: Community Engagement Efforts from PR-CEAL. 波多黎各妇女样本对流感疫苗接种以及宫颈癌、乳腺癌和大肠癌筛查的依从性：来自 PR-CEAL 的社区参与努力。

Puerto Rico health sciences journal Pub Date : 2023-12-01

Katherine Hill, Cynthia M Pérez, Adriana Pons-Calvo, Karelys Canales-Birriel, Andrea López-Cepero, Norangelys Solís-Torres, Zaydelis Tamarit-Quevedo, Vivian Colón-López

{"title":"Compliance with Influenza Vaccination and Cervical, Breast, and Colorectal Cancer Screening in a Sample of Women in Puerto Rico: Community Engagement Efforts from PR-CEAL.","authors":"Katherine Hill, Cynthia M Pérez, Adriana Pons-Calvo, Karelys Canales-Birriel, Andrea López-Cepero, Norangelys Solís-Torres, Zaydelis Tamarit-Quevedo, Vivian Colón-López","doi":"","DOIUrl":"","url":null,"abstract":"Objective: There are an estimated 5,570 yearly cancer deaths in Puerto Rico. Breast and colorectal are the most common malignancies among Puerto Rican women. Therefore, prevention and early detection of these cancer types are critical to reducing morbidity and mortality. This study assessed whether women who received the influenza vaccine had increased adherence to cervical, breast, and colorectal cancer screening.Methods: The Puerto Rico Community Engagement Alliance (PR-CEAL) against COVID-19 Disparities team attended community outreach events throughout Puerto Rico and completed a face-to-face survey among women 18 years or older. The survey gathered demographic information and adherence to influenza vaccination and cervical, breast, and colorectal screening in the past year. The initial sample included 400 women, of whom 347 met the age inclusion criteria (21-74 years). Chi-square tests were used to compare cancer screening adherence according to influenza vaccination status. A p-value <0.05 was considered statistically significant.Results: Of all participants, 47.0% received the influenza vaccine in the past year. Cancer screening rates among vaccinated and non-vaccinated women were as follows: 64.5% vs. and 13.0% vs. 8.0% for colorectal cancer (p-value=0.19).Conclusion: Adherence to cervical, breast, and colorectal cancer screening in the past year did not differ by influenza vaccination status. Influenza vaccination appointments may therefore represent a missed opportunity to promote preventative cancer screening in Puerto Rico.","PeriodicalId":94183,"journal":{"name":"Puerto Rico health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138807513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0