{"title":"HCM's hidden cost: The impact of socioeconomic status.","authors":"Christine M Park, Aldo L Schenone, Ahmad Masri","doi":"10.1016/j.pcad.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.pcad.2025.03.011","url":null,"abstract":"","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Socioeconomic milieu and culture: Forcing factors and the Most fundamental determinant of health.","authors":"Frederick J Zimmerman, Nicolaas P Pronk","doi":"10.1016/j.pcad.2025.03.007","DOIUrl":"10.1016/j.pcad.2025.03.007","url":null,"abstract":"<p><p>We introduce the concept of forcing factors, analogous to risk factors for population-wide health outcomes, that are attributes of the physical, social, legal, economic, or cultural environment that are common to all people in an identified population and that promote or inhibit particular outcomes of health, wellness, and well-being. Examples include laws governing food or tobacco marketing, the built environment, and climate change. Culture also functions as a forcing factor of health outcomes. In contrast to past explanations of adverse health outcomes that have relied on cultural attributes of a specific sub-population, we draw on work of John McKinlay to make the point that it is the shared culture of a country or a region that influences health outcomes. Culture itself operates in a particular cultural context.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cultural influences on choosing to move more and sit less.","authors":"Rıdvan Aktan, Grenita Hall, Cemal Ozemek","doi":"10.1016/j.pcad.2025.03.006","DOIUrl":"10.1016/j.pcad.2025.03.006","url":null,"abstract":"<p><p>Low levels of physical activity (PA) and prolonged periods of sedentary time significantly increase the risk of developing non-communicable diseases. Individuals who minimally increase their PA levels can experience significant reductions in risk of morbidity and mortality. Despite regular public messaging cycles and PA promotional campaigns highlighting these observations, the number of individuals meeting the PA recommendations has been underwhelming and stagnant for decades. Numerous studies have identified prominent barriers to becoming and staying physically active, in addition to a person's or people's cultural beliefs. Yet exercise professionals and other allied healthcare professionals may not consider one's cultural experiences when promoting PA. Recognizing the impact of culture on PA, whether it is positive or negative, can facilitate culturally sensitive discussions with individuals or groups and customizing PA recommendations in a way that facilitates its adoption. Accordingly, this paper aims to review relevant studies and examples of how culture can influence PA behaviors, as well as provide considerations for exercise professionals and allied healthcare providers to take when promoting PA in diverse populations.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed K Mahmoud, Juan M Farina, Milagros Pereyra, Isabel G Scalia, Niloofar Javadi, Donya Derakshani, Ali A Elahi, Katie Mand, Mustafa Suppah, Mohammed Tiseer Abbas, Moaz A Kamal, Kamal Awad, Chieh-Ju Chao, Vuyisile T Nkomo, Said Alsidawi, Kwan S Lee, Steven J Lester, Kristen A Sell-Dottin, David F Fortuin, John P Sweeney, Chadi Ayoub, Reza Arsanjani
{"title":"To the editor: Artificial intelligence applied to ECG predicts mortality after a transcatheter aortic valve replacement.","authors":"Ahmed K Mahmoud, Juan M Farina, Milagros Pereyra, Isabel G Scalia, Niloofar Javadi, Donya Derakshani, Ali A Elahi, Katie Mand, Mustafa Suppah, Mohammed Tiseer Abbas, Moaz A Kamal, Kamal Awad, Chieh-Ju Chao, Vuyisile T Nkomo, Said Alsidawi, Kwan S Lee, Steven J Lester, Kristen A Sell-Dottin, David F Fortuin, John P Sweeney, Chadi Ayoub, Reza Arsanjani","doi":"10.1016/j.pcad.2025.03.004","DOIUrl":"10.1016/j.pcad.2025.03.004","url":null,"abstract":"","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raoul R Wadhwa, Rohan M Desai, Shilpa Rao, Ala Alashi, Bo Xu, Susan Ospina, Nicholas G Smedira, Maran Thamilarasan, Zoran B Popovic, Milind Y Desai
{"title":"Association of neighborhood median income to outcomes in hypertrophic cardiomyopathy.","authors":"Raoul R Wadhwa, Rohan M Desai, Shilpa Rao, Ala Alashi, Bo Xu, Susan Ospina, Nicholas G Smedira, Maran Thamilarasan, Zoran B Popovic, Milind Y Desai","doi":"10.1016/j.pcad.2025.03.002","DOIUrl":"10.1016/j.pcad.2025.03.002","url":null,"abstract":"<p><strong>Background: </strong>Neighborhood median household income (NMHI), a key social determinant of health, is being recognized as a major source of inequity in healthcare. Its impact on patients with hypertrophic cardiomyopathy (HCM) is uncertain.</p><p><strong>Objective: </strong>We sought to study the association between NMHI and long-term outcomes of HCM patients.</p><p><strong>Methods: </strong>This was an observation registry of 6368 HCM patients (median age 56 years, 58 % men, 83 % white, 32 % with ≥1 sudden death risk factor) who underwent a clinical evaluation at a tertiary care center between 2002 and 18. NMHI (US$) was calculated from each patient's zip code, using data from the US Census Bureau and Department of Housing & Urban Development. The primary outcome was death, appropriate internal cardioverter defibrillator (ICD) discharge or heart transplant in follow up.</p><p><strong>Results: </strong>Patients were categorized as obstructive (oHCM, n = 3827 or 60 %, 65 % symptomatic, median NMHI $51,600) and nonobstructive (nHCM, n = 2541 or 40 %, 73 % asymptomatic, median NMHI $53,700) using echocardiography. At a median of 6 years (interquartile range or IQR 2.91, 9.74), there were 998 (16 %) primary events (deaths = 939), with breakdown as follows: 599/3827 (16 %) in oHCM and 399/2541 (16 %) in nHCM, respectively. On multivariable Cox survival analysis, a higher NMHI was independently associated with improved long-term freedom from primary events (oHCM [Hazard ratio or HR 0.84 95 % Confidence Interval or CI 0.80-0.88] and nHCM [HR 0.95 95 % CI 0.91-9.97]), both p < 0.01. On penalized spline analysis, the NMHI at which the hazard for primary events crossed 1 was ∼$52,000 for both oHCM and nHCM. In nHCM patients, NMHI greater than $52,000 was associated with improved longer-term freedom from primary events vs. those whose NMHI was lower than $52,000 (196/1398 [14 %] vs. 203/1143 [18 %], log-rank p-value<0.01). Similarly, oHCM patients with NMHI greater than $52,000 had significantly improved longer-term freedom from primary events vs. those whose NMHI was lower than $52,000 (186/2067 [9 %] vs. 413/1760 [23 %] vs., log-rank p-value<0.001).</p><p><strong>Conclusions: </strong>NMHI, a marker of socioeconomic status, is independently associated with outcomes in patients with HCM. oHCM patients below the NMHI cutoff had significantly worse long-term outcomes vs. the nHCM patients similarly below the NMHI cutoff.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Imtiaz Ahmad, Parag A Chevli, Saeid Mirzai, Rishi Rikhi, Harpeet Bhatia, Neha Pagidipati, Roger Blumenthal, Alexander C Razavi, Kathleen Ruddiman, Jared A Spitz, Khurram Nasir, Michael D Shapiro
{"title":"Waist to hip ratio modifies the cardiovascular risk of lipoprotein (a): Insights from MESA.","authors":"Muhammad Imtiaz Ahmad, Parag A Chevli, Saeid Mirzai, Rishi Rikhi, Harpeet Bhatia, Neha Pagidipati, Roger Blumenthal, Alexander C Razavi, Kathleen Ruddiman, Jared A Spitz, Khurram Nasir, Michael D Shapiro","doi":"10.1016/j.pcad.2025.03.001","DOIUrl":"10.1016/j.pcad.2025.03.001","url":null,"abstract":"<p><strong>Aims: </strong>To assess if adiposity measures such as waist-to-hip ratio (WHR) modify the relationship of lipoprotein (a) [Lp(a)] with atherosclerotic cardiovascular disease (ASCVD).</p><p><strong>Methods: </strong>4652 participants from the Multi-Ethnic Study of Atherosclerosis (MESA) were grouped as follows: Lp(a) < 50 mg/dl and WHR <90th percentile(pct) (reference); Lp(a) < 50 mg/dl and WHR ≥90th pct; Lp(a) ≥ 50 mg/dl and WHR <90th pct; and Lp(a) ≥50 mg/dl and WHR ≥90th pct. Cox proportional hazard models assessed the relationship of Lp(a) and WHR with time to ASCVD events.</p><p><strong>Results: </strong>Compared to the reference group, isolated elevated Lp(a) ≥ 50 mg/dl or WHR ≥90th pct were not significantly associated with risk of ASCVD (hazard ratio (HR), 1.15, 95 % confidence interval (CI): 0.94-1.39) and (HR, 1.14, 95 % CI: 0.92-1.41), respectively. In contrast, the combination of elevated Lp(a) ≥50 mg/dl and WHR ≥90th pct was associated with ASCVD risk (HR, 2.34, 95 % CI: 1.61-3.40). Lp(a) ≥50 mg/dl was not significantly associated with ASCVD risk in the 1st and 2nd tertile of WHR (HR, 1.06, 95 % CI: 0.72-1.48and HR, 1.08, 95 % CI: 0.79-1.48, respectively). However, Lp(a) ≥50 mg/dl was significantly associated with ASCVD risk in the highest tertile of WHR (HR, 1.60, 95 % CI: 1.23-2.09). (Interaction p = 0.01). Body mass index (BMI) and Lp(a) combinations resulted in similar greater risks of ASCVD in the highest risk category (HR, 1.33, 95 % CI: 1.00-1.77), without a significant interaction (p = 0.99).</p><p><strong>Conclusions: </strong>In MESA, WHR significantly modifies the risk of ASCVD associated with Lp(a). Measures of abdominal adiposity may further refine the cardiovascular risk in individuals with elevated Lp(a).</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Froelicher, Mustafa Husaini, Jason V Tso, Samuel Montalvo, Jeffrey Christle, Marco V Perez, David Hadley, Matthew Wheeler, Ricardo Stein, Victoria Vetter, Jeffrey J Hsu, Irfan M Asif, Kristofer Hedman, Anna Carlén, Kegan Moneghetti, Euan Ashley
{"title":"Proposed enhanced recommendations for interpretation of electrocardiographic screening of athletes.","authors":"Victor Froelicher, Mustafa Husaini, Jason V Tso, Samuel Montalvo, Jeffrey Christle, Marco V Perez, David Hadley, Matthew Wheeler, Ricardo Stein, Victoria Vetter, Jeffrey J Hsu, Irfan M Asif, Kristofer Hedman, Anna Carlén, Kegan Moneghetti, Euan Ashley","doi":"10.1016/j.pcad.2025.03.003","DOIUrl":"10.1016/j.pcad.2025.03.003","url":null,"abstract":"<p><p>While there is ongoing debate about the role of the 12‑lead Electrocardiogram (ECG) in the routine screening of young athletes during pre-participation evaluations, studies continue to support the use of ECG within properly organized settings. This paper aims to offer considerations for enhancing the International ECG recommendations for the interpretation of the ECGs of young athletes through an emphasis on 1) percentile outliers, 2) computerized ECG technology and 3) clarification of terminology. We specifically highlight criteria for early repolarization, left atrial abnormality, right bundle branch block, ST shifts, and high and low voltage QRS.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The culture of healthy living - Exploring the chaos that drives health behaviors.","authors":"Ross Arena, Nicolaas P Pronk, Colin Woodard","doi":"10.1016/j.pcad.2025.02.008","DOIUrl":"10.1016/j.pcad.2025.02.008","url":null,"abstract":"","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A culture of health promotion in healthcare: Can't pour from an empty cup.","authors":"Richard Severin, Ross Arena","doi":"10.1016/j.pcad.2025.02.007","DOIUrl":"10.1016/j.pcad.2025.02.007","url":null,"abstract":"<p><p>With chronic diseases increasingly prevalent in the United States (U.S.), healthcare providers are in a unique position to promote healthy living behaviors, such as physical activity (PA) and nutrition, to patients. However, many healthcare providers struggle with maintaining their own health, which negatively affects their ability to counsel patients effectively on these behaviors. This paper highlights the barriers healthcare providers face in adopting and promoting healthy behaviors, including individual habits, lack of training, and environmental factors within healthcare institutions. It also examines how these barriers, such as insufficient educational opportunities, inadequate work environments, and systemic obstacles like time constraints and reimbursement issues, hinder effective PA and nutritional counseling. The authors propose that improving the health of healthcare providers will enhance the quality of counseling they provide, ultimately benefiting patient care and population health.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}