Progress in cardiovascular diseases最新文献

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Cardioneuroablation: Three different approaches. 心脏神经消融术:三种不同的方法。
Progress in cardiovascular diseases Pub Date : 2025-04-04 DOI: 10.1016/j.pcad.2025.04.003
Medhat Farwati, Tolga Aksu, Enrique I Pachon, Tomas Santillana, Carlos Thiene Pachon, Pasquale Santangeli, Jose Carlos Pachon
{"title":"Cardioneuroablation: Three different approaches.","authors":"Medhat Farwati, Tolga Aksu, Enrique I Pachon, Tomas Santillana, Carlos Thiene Pachon, Pasquale Santangeli, Jose Carlos Pachon","doi":"10.1016/j.pcad.2025.04.003","DOIUrl":"https://doi.org/10.1016/j.pcad.2025.04.003","url":null,"abstract":"<p><p>Cardioneuroablation (CNA) is an emerging therapy for patients with vasovagal syncope with predominant cardioinhibitory responses. The procedure targets the neuromyocardial connections localized in specific regions of the right and left atrium as well as the adjacent ganglionated plexi (GP) providing parasympathetic innervation to the sinus and atrioventricular nodes. The target regions for CNA can be determined with various techniques, which result in heterogenous procedural approaches and endpoints in different centers specialized in this procedure. In this review we summarize the rationale and details of the procedural approach for three different techniques for CNA, namely: CNA controlled by extra-cardiac vagal stimulation, CNA guided by analysis of fractionated electrograms, and an anatomical approach to CNA.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contemporary management of ischemic cardiomyopathy: The synergy of medical, revascularization, and device therapies. 缺血性心肌病的当代管理:医学、血运重建和器械治疗的协同作用。
Progress in cardiovascular diseases Pub Date : 2025-04-03 DOI: 10.1016/j.pcad.2025.04.001
Ameesh Isath, Julio A Panza
{"title":"Contemporary management of ischemic cardiomyopathy: The synergy of medical, revascularization, and device therapies.","authors":"Ameesh Isath, Julio A Panza","doi":"10.1016/j.pcad.2025.04.001","DOIUrl":"https://doi.org/10.1016/j.pcad.2025.04.001","url":null,"abstract":"<p><p>Ischemic heart disease (IHD) is the leading global cause of death, affecting millions and leading to significant morbidity and mortality. Ischemic cardiomyopathy (ICM), a manifestation of IHD, results in severe left ventricular dysfunction due to coronary artery disease and poses a significant challenge due to the complex pathophysiology, variable clinical presentation, and overall poor prognosis. Recent advances in medical therapy, device interventions, and revascularization techniques offer newfound hope in improving ICM patient outcomes. This article reviews the state-of-the-art management approaches for ICM, emphasizing the importance of personalized treatment plans that integrate the various contemporary therapies to address the multiple mechanisms of disease development and progression. A meticulously tailored treatment approach for each individual patient offers the hope of prolonged survival through the synergy of therapies designed to address the different and complex mechanisms that contribute to their disease process.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic value of the right ventricular to left ventricular volume ratio on cardiac magnetic resonance imaging in predicting adverse outcomes for adults with pulmonary hypertension. 心脏磁共振成像右室与左室容积比预测成人肺动脉高压不良结局的预后价值。
Progress in cardiovascular diseases Pub Date : 2025-04-02 DOI: 10.1016/j.pcad.2025.04.002
Robert S Zhang, Lily Jin, Giorgia Falco, Rachel Axman, Pablo Villar-Calle, Annie Tsay, Matthew C Lam, Udhay Krishnan, Andre Cheng, Yuchi Han, Monica Mukherjee, Jonathan W Weinsaft, Jiwon Kim
{"title":"Prognostic value of the right ventricular to left ventricular volume ratio on cardiac magnetic resonance imaging in predicting adverse outcomes for adults with pulmonary hypertension.","authors":"Robert S Zhang, Lily Jin, Giorgia Falco, Rachel Axman, Pablo Villar-Calle, Annie Tsay, Matthew C Lam, Udhay Krishnan, Andre Cheng, Yuchi Han, Monica Mukherjee, Jonathan W Weinsaft, Jiwon Kim","doi":"10.1016/j.pcad.2025.04.002","DOIUrl":"https://doi.org/10.1016/j.pcad.2025.04.002","url":null,"abstract":"<p><strong>Background: </strong>Right ventricular (RV) performance impacts clinical outcomes across pulmonary hypertension (pH), yet noninvasive tools for early detection and risk stratification are limited. Cardiac MRI (CMR) derived RV to left ventricular (LV) volume ratio (RV/LV<sub>vol</sub> ratio) provides a relative assessment of RV size by normalizing chamber size to the LV. However, its prognostic utility remains underexplored. In the present study, we investigate the association between the RV/LV<sub>vol</sub> ratio and outcomes in patients with PH.</p><p><strong>Methods: </strong>This prospective study included patients with PH (pulmonary arterial systolic pressure > 35 mmHg by echocardiography or mean pulmonary artery pressure > 20 mmHg on invasive right heart catheterization), who underwent CMR. Abnormal RV/LV<sub>vol</sub> ratio cutoff (≥1.27) was applied and further tested using established gradation thresholds. The primary outcome was a composite of all-cause mortality and heart failure hospitalizations.</p><p><strong>Results: </strong>Of 135 patients, 56 (41.5 %) had an abnormal RV/LV<sub>vol</sub> ratio. After a mean follow-up of 1.9 ± 1.3 years, 75 patients experienced the primary outcome. Patients with an abnormal RV/LV<sub>vol</sub> ratio had higher rates of the primary outcome (64.3 % vs 50.0 %, p = 0.02). After multivariable analysis adjusting for age and CMR indices, abnormal RV/LV<sub>vol</sub> ratio was associated with a higher risk of the primary outcome (HR 1.81 [95 % CI 1.06-2.97]; p = 0.003). RV/LV<sub>vol</sub> ratio added incremental prognostic value over age and traditional RV indices (global χ2 value increasing from 6.7 to 17.4, p = 0.006).</p><p><strong>Conclusions: </strong>The RV/LV<sub>vol</sub> ratio is a simple clinical tool associated with an increased risk of adverse outcomes in PH patients, offering prognostic information beyond traditional RV parameters.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The American Nations model: An analytical tool for understanding the influence of U.S. regional cultures on health and the social and political determinants of health. 美国国家模式:了解美国地区文化对健康的影响以及健康的社会和政治决定因素的分析工具。
Progress in cardiovascular diseases Pub Date : 2025-03-28 DOI: 10.1016/j.pcad.2025.03.014
Colin Woodard, Ross Arena, Nicolaas P Pronk
{"title":"The American Nations model: An analytical tool for understanding the influence of U.S. regional cultures on health and the social and political determinants of health.","authors":"Colin Woodard, Ross Arena, Nicolaas P Pronk","doi":"10.1016/j.pcad.2025.03.014","DOIUrl":"10.1016/j.pcad.2025.03.014","url":null,"abstract":"<p><p>Cardiovascular disease (CVD) represents a significant health crisis, leading to premature morbidity and mortality, that is largely preventable. A decade ago, the World Health Organization formally acknowledged the powerful role culture plays in health and well-being, a key factor in preventing CVD, prompting increased attention on how shared values, norms, symbols, ethics and life practices effect the decisions and behaviors of patients, populations and practitioners alike. Cultural contexts affect human behaviors and health outcomes, and the United States (U.S.) is divided between dominant regional cultures. The American Nations model, informed by the work of cultural geographers, historians, and anthropologists, provides an analytical framework for understanding regional cultural contexts within the U.S. This model has been used to demonstrate significant regional differences in health outcomes, wellbeing, lifestyle behaviors, lifespan, and social vulnerability, with communitarian cultures consistently outperforming individualistic cultures across a broad range of phenomena. This model has significant implications for how a nation approaches health and health care, shifting from the traditional, national level one-size-fits-all paradigm to one that considers distinct regional differences based on historical settlement patterns. In this context, the American Nations model can help improve the effectiveness of health interventions by supporting a better understanding of cultural differences and the dominant U.S. cultural landscapes.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The culture of healthy living in communities. 社区中健康生活的文化。
Progress in cardiovascular diseases Pub Date : 2025-03-26 DOI: 10.1016/j.pcad.2025.03.015
Ross Arena, Grenita Hall
{"title":"The culture of healthy living in communities.","authors":"Ross Arena, Grenita Hall","doi":"10.1016/j.pcad.2025.03.015","DOIUrl":"https://doi.org/10.1016/j.pcad.2025.03.015","url":null,"abstract":"<p><p>What defines a group of individuals as part of a community is broadly interpreted and depends on the context of the group being categorized. For this review, community may be defined as \"as a group of people with diverse characteristics who are linked by social ties, share common perspectives, and engage in joint action in geographical locations or settings\". A given community will possess unique cultural attributes, defined by the American Psychological Association as \"the values, beliefs, language, rituals, traditions, and other behaviors that are passed from one generation to another within any social group\". Unhealthy lifestyle behaviors drive the unacceptably high incidence and prevalence of chronic disease in the United States. Despite well intentioned efforts, society appears to be failing at altering the trajectory of unhealthy lifestyle behaviors, from an individual to population level. Perhaps our oftentimes one size fits all approach to health behavior messaging and counseling is a critical shortcoming. The fact that being more physically active, not smoking and consuming a healthier diet is of great benefit to human physiology and therefore human health outcomes is clear. However, human health behaviors or decisions to make a change in behavior are not driven by physiology but rather a complexly interacting milieu of factors - cultural drivers unique to a community amongst them. Herein, we discuss several community settings where there are opportunities to promote a culture of health living. This review will focus on settings that embody the definitions of community and culture described previously.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An ecological framework for population health and well-being. 人口健康和福祉的生态框架。
Progress in cardiovascular diseases Pub Date : 2025-03-26 DOI: 10.1016/j.pcad.2025.03.013
Nicolaas P Pronk, Colin Woodard, Frederick J Zimmerman, Ross Arena
{"title":"An ecological framework for population health and well-being.","authors":"Nicolaas P Pronk, Colin Woodard, Frederick J Zimmerman, Ross Arena","doi":"10.1016/j.pcad.2025.03.013","DOIUrl":"10.1016/j.pcad.2025.03.013","url":null,"abstract":"<p><p>Social structures have become focal points in considering how to address the circumstances and conditions under which people live their lives. Yet, the many interactions among multiple factors that make up social and structural determinants are complex, interdependent, interactive, dynamic, and multilevel. This paper introduces an evidence-informed ecological framework that organizes drivers and feedback mechanisms collectively representing a generative force towards population health and well-being. The proposed ecological framework supports explanatory and exploratory considerations for prevention and management of population health and well-being issues. The framework explicitly includes a recognition that successful health and well-being outcomes are often dependent on the presence of social capital and healthy power dynamics. Dominant cultural norm is positioned as an overarching driver in this framework because it shapes the political realities and power dynamics responsible for infrastructure as well as the habits and behaviors of people at both the individual and social levels.</p>","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assorted topics in cardiovascular disease 2025: Novel insights in prevention, diagnosis, and treatment. 2025年心血管疾病分类主题:预防、诊断和治疗方面的新见解。
Progress in cardiovascular diseases Pub Date : 2025-03-22 DOI: 10.1016/j.pcad.2025.03.008
Leandro Slipczuk
{"title":"Assorted topics in cardiovascular disease 2025: Novel insights in prevention, diagnosis, and treatment.","authors":"Leandro Slipczuk","doi":"10.1016/j.pcad.2025.03.008","DOIUrl":"10.1016/j.pcad.2025.03.008","url":null,"abstract":"","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143695022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stepping up physical activity and fitness is needed for longevity. 要想长寿,就必须加强体育锻炼,增强体质。
Progress in cardiovascular diseases Pub Date : 2025-03-22 DOI: 10.1016/j.pcad.2025.03.012
Carl J Lavie, Fabian Sanchis-Gomar, Andre La Gerche, Jari A Laukkanen
{"title":"Stepping up physical activity and fitness is needed for longevity.","authors":"Carl J Lavie, Fabian Sanchis-Gomar, Andre La Gerche, Jari A Laukkanen","doi":"10.1016/j.pcad.2025.03.012","DOIUrl":"10.1016/j.pcad.2025.03.012","url":null,"abstract":"","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143695026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Continuing a legacy of excellence: A new chapter for Progress in cardiovascular diseases. 继续卓越的遗产:心血管疾病进展的新篇章。
Progress in cardiovascular diseases Pub Date : 2025-03-22 DOI: 10.1016/j.pcad.2025.03.010
Leandro Slipczuk
{"title":"Continuing a legacy of excellence: A new chapter for Progress in cardiovascular diseases.","authors":"Leandro Slipczuk","doi":"10.1016/j.pcad.2025.03.010","DOIUrl":"10.1016/j.pcad.2025.03.010","url":null,"abstract":"","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143695024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Refining cardiovascular risk assessment: The interplay of lipoprotein (a) and waist-to-hip ratio. 完善心血管风险评估:脂蛋白(a)和腰臀比的相互作用。
Progress in cardiovascular diseases Pub Date : 2025-03-22 DOI: 10.1016/j.pcad.2025.03.009
Annalisa Filtz, Martha Gulati
{"title":"Refining cardiovascular risk assessment: The interplay of lipoprotein (a) and waist-to-hip ratio.","authors":"Annalisa Filtz, Martha Gulati","doi":"10.1016/j.pcad.2025.03.009","DOIUrl":"10.1016/j.pcad.2025.03.009","url":null,"abstract":"","PeriodicalId":94178,"journal":{"name":"Progress in cardiovascular diseases","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143695025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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