Photodiagnosis and photodynamic therapy最新文献

{"title":"The Effect of Two Different Types of Daily Disposable Monofocal Contact Lenses on Ocular Wavefront Aberrations: (Impact of Daily Disposable Contact Lenses on Ocular Wavefront Aberrations).","authors":"Konuralp Yakar","doi":"10.1016/j.pdpdt.2025.104780","DOIUrl":"https://doi.org/10.1016/j.pdpdt.2025.104780","url":null,"abstract":"<p><strong>Background: </strong>To compare the effect of two daily disposable soft contact lenses on ocular wavefront aberrations.</p><p><strong>Methods: </strong>This study included 34 eyes from 17 patients aged 18 to 40 years (mean age: 27.12±8.3 years) with identical myopic refractive errors in both eyes without astigmatism and requesting contact lens use. Initially, wavefront aberrations; total, tilt, high, total coma, total trefoil, total 4.foil, sphere, high astigmatism, RMS (3mm/5mm) were measured using Nidek OPD Scan II aberrometer/topograph in both eyes without contact lenses. Acuvue Oasys with HydraLuxe 1-Day (senofilcon A) daily disposable contact lenses were applied to the right eye, while Precision 1 (verofilcon A) daily disposable contact lenses were applied to the left eye based on refractive errors. Wavefront aberration measurements were repeated 60 min later with contact lenses, and aberrations were compared to baseline and fellow eyes' measurements. The magnitudes of aberration changes after contact lens application were analyzed.</p><p><strong>Results: </strong>Both types of daily disposable contact lenses reduced total wavefront aberrations. Acuvue Oasys with HydraLuxe 1-Day contact lenses showed a significant increase in total trefoil aberration (p=0.048). Precision 1 contact lenses showed a significant increase (p=0.034) only in total tilt aberrations compared to baseline. No significant differences were found between the lenses regarding changes in all wavefront aberrations.</p><p><strong>Conclusion: </strong>Both daily disposable lenses effectively reduced total wavefront aberrations, though they increased certain subtypes of high-order aberrations in young adult myopes.</p>","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104780"},"PeriodicalIF":2.6,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organizer's Remarks.","authors":"","doi":"10.1016/j.pdpdt.2025.104776","DOIUrl":"10.1016/j.pdpdt.2025.104776","url":null,"abstract":"","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104776"},"PeriodicalIF":2.6,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IPA 2025 Shanghai: Photodynamic brilliance illuminates the Huangpu riverfront.","authors":"Xiuli Wang","doi":"10.1016/j.pdpdt.2025.104777","DOIUrl":"10.1016/j.pdpdt.2025.104777","url":null,"abstract":"","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104777"},"PeriodicalIF":2.6,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The presidential remarks.","authors":"","doi":"10.1016/j.pdpdt.2025.104775","DOIUrl":"10.1016/j.pdpdt.2025.104775","url":null,"abstract":"","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104775"},"PeriodicalIF":2.6,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What is the Long-Term Efficacy and Safety of Selective Laser Trabeculoplasty in the Management of Primary Open-Angle Glaucoma? A Systematic Review and Meta-Analysis.","authors":"Kai-Yang Chen, Hoi-Chun Chan, Chi-Ming Chan","doi":"10.1016/j.pdpdt.2025.104743","DOIUrl":"https://doi.org/10.1016/j.pdpdt.2025.104743","url":null,"abstract":"<p><strong>Background: </strong>Selective laser trabeculoplasty (SLT) is a laser-based intervention used to lower intraocular pressure (IOP) in patients with primary open-angle glaucoma (POAG). It has been adopted as both a primary and adjunctive therapy, with growing interest in its long-term outcomes. This systematic review and meta-analysis aimed to assess the long-term efficacy and safety of SLT in adult patients with POAG, with a focus on sustained IOP control, reduction in medication burden, preservation of visual function, and adverse event incidence.</p><p><strong>Methods: </strong>This review was conducted in accordance with PRISMA 2020 and MOOSE guidelines and was prospectively registered in PROSPERO (CRD420251030192). A systematic literature search was performed on June 16, 2025, across PubMed, Embase, Medline, and Scopus, including all records from database inception to the search date. Randomized controlled trials and observational studies reporting SLT outcomes with a minimum follow-up duration of 12 months were included. Primary outcomes included long-term IOP reduction and SLT failure rates. Secondary outcomes included medication use, visual field changes, and adverse events. Study quality was assessed using ROB-2 and Newcastle-Ottawa tools. Data were synthesized using random-effects models, and inter-study heterogeneity was quantified using the I² statistic.</p><p><strong>Results: </strong>From 3,462 identified records, 60 clinical studies were included for qualitative synthesis and 50 were included in the meta-analysis, representing a pooled sample of 8,934 eyes. SLT achieved IOP reduction comparable to topical medications at 6-12 months post-treatment (mean difference: 0.04 mmHg; 95% CI: -0.27 to 0.34). Medication use significantly decreased following SLT (mean reduction: -0.87 medications; 95% CI: -1.13 to -0.62). Visual field mean deviation improved by 0.79 dB (95% CI: 0.76 to 0.82), and SLT was associated with minimal short-term IOP spikes. The health-related quality-of-life scores, as measured by EQ-5D, showed modest but consistent improvements. Risk of bias and publication bias were low in most domains.</p><p><strong>Conclusion: </strong>SLT demonstrated sustained long-term efficacy in reducing intraocular pressure and minimizing pharmacological burden in patients with POAG. It maintained visual function over extended follow-up and was associated with a favorable safety profile, including a low incidence of adverse events and IOP spikes. These findings support the use of SLT as an effective and safe long-term management option for POAG and justify its consideration as a first-line or adjunctive therapy in clinical practice.</p>","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104743"},"PeriodicalIF":2.6,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjunctive use of photodynamic therapy in refractory cutaneous granuloma caused by Mycobacterium marinum infection: A case report.","authors":"Mao Li, Li Song, Yalin Zhang, Jiaojiao Pei, Mao Lu","doi":"10.1016/j.pdpdt.2025.104753","DOIUrl":"10.1016/j.pdpdt.2025.104753","url":null,"abstract":"<p><p>Mycobacterium marinum is a major species of nontuberculous mycobacteria (NTM) responsible for skin infections, commonly affecting aquatic animals and humans. The typical histopathological pattern of cutaneous M. marinum infection is suppurative granuloma. Antibiotics are the first-line treatment; however, they often require prolonged courses, are associated with significant side effects, and carry a risk of drug resistance. Aminolevulinic acid photodynamic therapy (ALA-PDT) represents a safe and effective therapeutic option for cutaneous M. marinum infections, particularly in drug-resistant cases. This report describes a patient with cutaneous granuloma caused by M. marinum infection who showed no significant improvement after two months of oral triple-antibiotic therapy. Subsequently, while continuing oral antibiotics, the patient underwent ALA-PDT once weekly for 4 consecutive weeks. Following four treatment sessions, the nodules, plaques, and ulcers on both the wrist and forearm were completely eradicated, with no recurrence observed during the 6-month follow-up period. This case suggests that adjunctive ALA-PDT, acting locally, can potentially reduce treatment duration and minimize systemic antibiotic-related side effects and adverse reactions, offering a valuable alternative for patients with suboptimal responses to antibiotic therapy alone.</p>","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104753"},"PeriodicalIF":2.6,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myopic Laser-assisted In-situ Keratomileusis (LASIK) with InnovEyes ablation: a review of literature.","authors":"Yuen Tsing Adeline Ho, Sunny Chi Lik Au","doi":"10.1016/j.pdpdt.2025.104671","DOIUrl":"https://doi.org/10.1016/j.pdpdt.2025.104671","url":null,"abstract":"","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104671"},"PeriodicalIF":0.0,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annals of photodynamic therapy: Publish and/or perish?","authors":"David Kessel","doi":"10.1016/j.pdpdt.2024.104398","DOIUrl":"10.1016/j.pdpdt.2024.104398","url":null,"abstract":"","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"104398"},"PeriodicalIF":0.0,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introduction to 18th International Photodynamic Association World Congress.","authors":"Dr. Lothar Lilge","doi":"10.1016/j.pdpdt.2024.104079","DOIUrl":"https://doi.org/10.1016/j.pdpdt.2024.104079","url":null,"abstract":"","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":"88 3","pages":"104079"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigations on correlations between changes of optical tissue properties and NMR relaxation times.","authors":"Maximilian Aumiller, Asmerom Arazar, Ronald Sroka, Olaf Dietrich, Adrian Rühm","doi":"10.1016/j.pdpdt.2024.103968","DOIUrl":"10.1016/j.pdpdt.2024.103968","url":null,"abstract":"<p><strong>Background: </strong>Accurate light dosimetry is a complex remaining challenge in interstitial photodynamic therapy (iPDT) for malignant gliomas. The light dosimetry should ideally be based on the tissue morphology and the individual optical tissue properties of each tissue type in the target region. First investigations are reported on using NMR information to estimate changes of individual optical tissue properties.</p><p><strong>Methods: </strong>Porcine brain tissue and optical tissue phantoms were investigated. To the porcine brain, supplements were added to simulate an edema or high blood content. The tissue phantoms were based on agar, Lipoveneous, ink, blood and gadobutrol (Gd-based MRI contrast agent). The concentrations of phantom ingredients and tissue additives are varied to compare concentration-dependent effects on optical and NMR properties. A 3-tesla whole-body MRI system was used to determine T₁ and T₂ relaxation times. Optical tissue properties, i.e., the spectrally resolved absorption and reduced scattering coefficient, were obtained using a single integrating sphere setup. The observed changes of NMR and optical properties were compared to each other.</p><p><strong>Results: </strong>By adjusting the NMR relaxation times and optical tissue properties of the tissue phantoms to literature values, recipes for human brain tumor, white matter and grey matter tissue phantoms were obtained that mimic these brain tissues simultaneously in both properties. For porcine brain tissue, it was observed that with increasing water concentration in the tissue, both NMR-relaxation times increased, while µ_a decreased and µ_s' increased at 635 nm. The addition of blood to porcine brain samples showed a constant T₁, while T₂ shortened and the absorption coefficient at 635 nm increased.</p><p><strong>Conclusions: </strong>In this investigation, by changing sample contents, notable changes of both NMR relaxation times and optical tissue properties have been observed and their relations examined. The developed dual NMR/optical tissue phantoms can be used in iPDT research, clinical training and demonstrations.</p>","PeriodicalId":94170,"journal":{"name":"Photodiagnosis and photodynamic therapy","volume":" ","pages":"103968"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}