Neurologia最新文献

{"title":"Hereditary spastic paraparesis due to SPG5/CYP7B1 mutation with potential therapeutic implications","authors":"P. Pérez-Torre , E. García Galloway , J.L. López-Sendón Moreno","doi":"10.1016/j.nrleng.2023.10.005","DOIUrl":"10.1016/j.nrleng.2023.10.005","url":null,"abstract":"","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 9","pages":"Pages 710-711"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2173580823000603/pdfft?md5=e5f43444bae1ce3d5bbcba49a5ff077c&pid=1-s2.0-S2173580823000603-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telemedicine in the management of patients with headache: current situation and recommendations of the Spanish Society of Neurology’s Headache Study Group","authors":"R. Belvís ,&nbsp;S. Santos-Lasaosa ,&nbsp;P. Irimia ,&nbsp;R.L. Blanco ,&nbsp;M. Torres-Ferrús ,&nbsp;N. Morollón ,&nbsp;A. López-Bravo ,&nbsp;D. García-Azorín ,&nbsp;A. Mínguez-Olaondo ,&nbsp;Á. Guerrero ,&nbsp;J. Porta ,&nbsp;E. Giné-Ciprés ,&nbsp;Á. Sierra ,&nbsp;G. Latorre ,&nbsp;C. González-Oria ,&nbsp;J. Pascual ,&nbsp;D. Ezpeleta","doi":"10.1016/j.nrleng.2023.10.001","DOIUrl":"10.1016/j.nrleng.2023.10.001","url":null,"abstract":"<div><h3>Introduction</h3><p>The COVID-19 pandemic has caused an unexpected boost to telemedicine. We analyse the impact of the pandemic on telemedicine applied in Spanish headache consultations, review the literature, and issue recommendations for the implementation of telemedicine in consultations.</p></div><div><h3>Method</h3><p>The study comprised 3 phases: <em>1)</em> review of the MEDLINE database since 1958 (first reported experience with telemedicine); <em>2)</em> Google Forms survey sent to all members of the Spanish Society of Neurology’s Headache Study Group (GECSEN); and <em>3)</em> online consensus of GECSEN experts to issue recommendations for the implementation of telemedicine in Spain.</p></div><div><h3>Results</h3><p>COVID-19 has increased waiting times for face-to-face consultations, increasing the use of all telemedicine modalities: landline telephone (from 75% before April 2020 to 97% after), mobile telephone (from 9% to 27%), e-mail (from 30% to 36%), and video consultation (from 3% to 21%). Neurologists are aware of the need to expand the availability of video consultations, which are clearly growing, and other e-health and m-health tools.</p></div><div><h3>Conclusions</h3><p>The GECSEN recommends and encourages all neurologists who assist patients with headaches to implement telemedicine resources, with the optimal objective of offering video consultation to patients under 60-65 years of age and telephone calls to older patients, although each case must be considered on an individual basis. Prior approval and advice must be sought from legal and IT services and the centre’s management. Most patients with stable headache and/or neuralgia are eligible for telemedicine follow-up, after a first consultation that must always be held in person.</p></div>","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 9","pages":"Pages 635-646"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2173580823000536/pdfft?md5=9cfc5bfe492fa72fcb341375e8932911&pid=1-s2.0-S2173580823000536-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognosis of patients with severe cerebral venous thrombosis treated with decompressive craniectomy","authors":"A. Arauz ,&nbsp;M.A. Barboza ,&nbsp;L.C. Quintero ,&nbsp;C. Cantu ,&nbsp;E. Chiquete ,&nbsp;F. Serrano","doi":"10.1016/j.nrleng.2021.04.009","DOIUrl":"10.1016/j.nrleng.2021.04.009","url":null,"abstract":"<div><h3>Introduction</h3><p>Despite the highly favorable prognosis, mortality occurs in nearly 2% of patients with cerebral venous thrombosis (CVT), in which decompressive craniectomy (DC) may be the only way to save the patient's life. The aim of this report is to describe the risk factors, neuroimaging features, in-hospital complications and functional outcome of severe CVT in patients treated with DC.</p></div><div><h3>Materials and methods</h3><p>Consecutive malignant CVT cases treated with DC from a retrospective third-level hospital database were analyzed. Demographic, clinical, and functional outcomes were analyzed.</p></div><div><h3>Results</h3><p>Twenty-six patients were included (20 female, age 35.4<!--> <!-->±<!--> <!-->12.1 years); 53.8% of the patients had acute CVT, with neurological focalization as the most common symptom in 92.3% of the patients. Superior sagittal sinus thromboses were found in 84.6% of cases. Bilateral lesions were present in 10 patients (38.5%). Imaging on admission showed a parenchymal lesion (venous infarction<!--> <!-->±<!--> <!-->hemorrhagic lesion)<!--> <!-->&gt;<!--> <!-->6<!--> <!-->cm measured along the longest diameter in 25 patients (96.2%). Mean duration of clinical neurological deterioration was 3.5 days; eleven patients (42.3%) died during hospitalization.</p></div><div><h3>Conclusion</h3><p>In patients with severe forms of CVT, we found higher mortality than previously reported. DC is an effective life-saving treatment with acceptable functional prognosis for survivors.</p></div>","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 9","pages":"Pages 617-624"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2173580822001663/pdfft?md5=cb907e33e57bfd27d0b83f2f2ff9b807&pid=1-s2.0-S2173580822001663-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral amyloid angiopathy–related inflammation: clinical features and treatment response in a case series","authors":"P. Martín-Jiménez ,&nbsp;M. Sánchez-Tornero ,&nbsp;S. Llamas-Velasco ,&nbsp;M.P. Guerrero-Molina ,&nbsp;M. González-Sánchez ,&nbsp;A. Herrero-San Martín ,&nbsp;V. Blanco-Palmero ,&nbsp;P. Calleja-Castaño ,&nbsp;J. Francisco-Gonzalo ,&nbsp;A. Hilario ,&nbsp;A. Ramos ,&nbsp;E. Salvador ,&nbsp;Ó. Toldos ,&nbsp;A. Hernández-Lain ,&nbsp;D.A. Pérez-Martínez ,&nbsp;A. Villarejo-Galende","doi":"10.1016/j.nrleng.2023.07.002","DOIUrl":"10.1016/j.nrleng.2023.07.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Cerebral amyloid angiopathy–related inflammation (CAA-ri) is an entity characterised by an inflammatory response to β-amyloid deposition in the walls of cerebral microvessels.</p></div><div><h3>Methods</h3><p>We conducted a retrospective review of a series of patients with a diagnosis of CAA-ri according to histopathological study findings or clinical-radiological diagnostic criteria.</p></div><div><h3>Results</h3><p>The study included 7 patients (5 men) with a mean age of 79 years. Disease onset was acute or subacute in 6 patients. The most frequent symptoms were cognitive impairment (n = 6), behavioural alterations (n = 5), epileptic seizures (n = 5), focal neurological signs (n = 4), and headache (n = 2). Cerebrospinal fluid was abnormal in 3 patients (lymphocytic pleocytosis and high protein levels). The most frequent MRI findings were microbleeds (n = 7), subcortical white matter hyperintensities on T2-FLAIR sequences (n = 7), and leptomeningeal enhancement (n = 6). Lesions were bilateral in 3 patients and most frequently involved the parieto-occipital region (n = 5). Amyloid PET studies were performed in 2 patients, one of whom showed pathological findings. Two patients underwent brain biopsy, which confirmed diagnosis. All patients received immunosuppressive therapy. An initially favourable clinical-radiological response was observed in all cases, with 2 patients presenting radiological recurrence after treatment withdrawal, with a subsequent improvement after treatment was resumed.</p></div><div><h3>Conclusions</h3><p>Early diagnosis of CAA-ri is essential: early treatment has been shown to improve prognosis and reduce the risk of recurrence. Although a histopathological study is needed to confirm diagnosis, clinical-radiological criteria enable diagnosis without biopsy.</p></div>","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 8","pages":"Pages 550-559"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9903335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct carotid puncture for the endovascular treatment of acute ischaemic stroke associated to aortic arch atheroma","authors":"I. Saldaña-Inda ,&nbsp;E. Garcés-Antón ,&nbsp;J.M. Navasa-Melado ,&nbsp;C. Bernal-Lafuente ,&nbsp;H. Tejada-Meza","doi":"10.1016/j.nrleng.2023.07.008","DOIUrl":"10.1016/j.nrleng.2023.07.008","url":null,"abstract":"","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 8","pages":"Pages 606-607"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41167818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of new technologies on neurology in Spain. Review by the New Technologies Ad-Hoc Committee of the Spanish Society of Neurology","authors":"R. López-Blanco ,&nbsp;A. Sorrentino Rodriguez ,&nbsp;E. Cubo ,&nbsp;Í. Gabilondo ,&nbsp;D. Ezpeleta ,&nbsp;M.Á. Labrador-Espinosa ,&nbsp;Á. Sánchez-Ferro ,&nbsp;C. Tejero ,&nbsp;M. Matarazzo ,&nbsp;on behalf of the SEN's New Technologies Ad-Hoc Committee","doi":"10.1016/j.nrleng.2020.10.011","DOIUrl":"10.1016/j.nrleng.2020.10.011","url":null,"abstract":"<div><h3>Introduction</h3><p>New technologies are increasingly widespread in biomedicine. Using the consensus definition of new technologies established by the New Technologies Ad-Hoc Committee of the Spanish Society of Neurology (SEN), we evaluated the impact of these technologies on Spanish neurology, based on communications presented at Annual Meetings of the SEN.</p></div><div><h3>Material and methods</h3><p>We defined the concept of new technology in neurology as a novel technology or novel application of an existing technology, characterised by a certain degree of coherence persisting over time, with the potential to have an impact on the present and/or future of neurology. We conducted a descriptive study of scientific communications presented at the SEN’s annual meetings from 2012 to 2018, analysing the type of technology, the field of neurology, and the geographical provenance of the studies.</p></div><div><h3>Results</h3><p>We identified 299 communications related with new technologies from a total of 8139 (3.7%), including 120 posters and 179 oral communications, ranging from 1.6% of all communications in 2012 to 6.8% in 2018. The technologies most commonly addressed were advanced neuroimaging (24.7%), biosensors (17.1%), electrophysiology and neurostimulation (14.7%), and telemedicine (13.7%). The neurological fields where new technologies were most widely employed were movement disorders (18.4%), cerebrovascular diseases (15.7%), and dementia (13.4%). Madrid was the region presenting the highest number of communications related to new technologies (32.8%), followed by Catalonia (26.8%) and Andalusia (9.0%).</p></div><div><h3>Conclusions</h3><p>The number of communications addressing new technologies follows an upward trend. The number of technologies used in neurology has increased in parallel with their availability. We found scientific communications in all neurological subspecialties, with a heterogeneous geographical distribution.</p></div>","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 8","pages":"Pages 591-598"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40510483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical profile, antibiotic treatment, and risk of stroke in patients with infective endocarditis","authors":"J. Rodríguez-Montolio ,&nbsp;D. Meseguer-Gonzalez ,&nbsp;M. Almeida-Zurita ,&nbsp;S. Santos- Lasaosa","doi":"10.1016/j.nrleng.2022.09.009","DOIUrl":"10.1016/j.nrleng.2022.09.009","url":null,"abstract":"","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 8","pages":"Pages 603-605"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10367166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of botulinum toxin type A in functionality, synkinesis and quality of life in peripheral facial palsy sequelae","authors":"U. Díaz-Aristizabal,&nbsp;M. Valdés-Vilches,&nbsp;T.R. Fernández-Ferreras,&nbsp;E. Calero-Muñoz,&nbsp;E. Bienzobas-Allué,&nbsp;L. Aguilera-Ballester,&nbsp;J. Carnicer-Cáceres","doi":"10.1016/j.nrleng.2023.07.003","DOIUrl":"10.1016/j.nrleng.2023.07.003","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to assess the effects of botulinum toxin A (BTX-A) infiltration on face muscle function, synkinesis, and quality of life in patients with sequelae of peripheral facial palsy (PFP).</p></div><div><h3>Material and methods</h3><p>We present the results of a prospective study including a sample of 20 patients with sequelae of PFP (15 women, 5 men) who underwent BTX-A (Botox© or Xeomin©) infiltration. All patients had previously received personalised treatment with neuromuscular retraining. A clinical assessment was performed before BTX-A infiltration and 4 weeks after treatment. The effect of BTX-A on face muscle function, quality of life, and synkinesis was evaluated using the Sunnybrook Facial Grading System (SFGS), the Facial Clinimetric Evaluation (FaCE) questionnaire, and the Synkinesis Assessment Questionnaire (SAQ), respectively.</p></div><div><h3>Results</h3><p>Mean SFGS scores increased from 64.8 to 69.9 after BTX-A infiltration (<em>P</em> <!-->=<!--> <!-->.004). Increases were also observed in mean total FaCE scores (from 52.42 to 64.5; <em>P</em> <!-->&lt;<!--> <!-->.001) and the mean score on the FaCE social function subscale (from 61.15 to 78.44; <em>P</em> <!-->&lt;<!--> <!-->.001). Mean SAQ scores decreased from 46.22 to 37.55 after BTX-A infiltration (<em>P</em> <!-->=<!--> <!-->.001).</p></div><div><h3>Conclusions</h3><p>BTX-A infiltration increases face muscle function, improves quality of life, and reduces synkinesis in patients with sequelae of PFP.</p></div>","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 8","pages":"Pages 560-565"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9833825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inequity of access to new migraine treatments","authors":"P. Irimia ,&nbsp;R. Belvís ,&nbsp;N. González-García ,&nbsp;J. García-Ull ,&nbsp;J.M. Lainez","doi":"10.1016/j.nrleng.2022.08.004","DOIUrl":"10.1016/j.nrleng.2022.08.004","url":null,"abstract":"","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 8","pages":"Pages 599-600"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10053679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of the Low-Profile Visualized Intraluminal Support stent in treating intracranial atherosclerotic stenosis","authors":"J.-W. Wang,&nbsp;X.-Y. Li,&nbsp;C.-H. Li,&nbsp;J.-F. Liu,&nbsp;H. Li,&nbsp;Y.-Y. Tian,&nbsp;B.-L. Gao","doi":"10.1016/j.nrleng.2023.07.005","DOIUrl":"10.1016/j.nrleng.2023.07.005","url":null,"abstract":"<div><h3>Purpose</h3><p>The performance of the Low-Profile Visualized Intraluminal Support (LVIS) stent deployed following balloon angioplasty is unknown in treating intracranial atherosclerotic stenosis, and this study was to investigate the safety and efficacy of the LVIS stent in treating intracranial atherosclerotic stenosis in the middle cerebral artery M1 segment.</p></div><div><h3>Methods</h3><p>Thirty-five patients were enrolled with 35 atherosclerotic stenoses at the M1 segment. The stenosis was about 75% in 16 patients, 80% in 15, and 90% in the rest four. The LVIS stent was used to treat these patients.</p></div><div><h3>Results</h3><p>The success rate of stenting was 97.1%. The stenting procedure was failed in one patient because of intraprocedural dissection of the stenotic (75%) segment, resulting in a 30-day periprocedural complication rate of 2.9% (1/35). Before stenting, the stenosis rate ranged 75%–90% (mean 78.9%<!--> <!-->±<!--> <!-->4.7%), and after stenting, the diameter of the stented segment was significantly (<em>P</em> <!-->&lt;<!--> <!-->0.0001) increased to 1.5–3.4<!--> <!-->mm (mean 2.1<!--> <!-->±<!--> <!-->0.32<!--> <!-->mm) ranging 68.2%–100% (mean 94.0%<!--> <!-->±<!--> <!-->5.8%) of the normal arterial diameter, with the residual stenosis ranging 0–31.8% (median 4.8%, IQR 2.4%–7.3%). Follow-up was performed at 6–20 months (mean 8.5) after stenting. One patient (2.9%) had occlusion of the stented M1 segment with no symptoms, and two patients (5.7%) had slight asymptomatic instent stenosis (40%) at the M1 segment, with the instent restenosis and occlusion rate of 8.6% (3/35).</p></div><div><h3>Conclusion</h3><p>The braided LVIS stent can be safely applied for treatment of intracranial atherosclerotic stenosis in the middle cerebral artery with good safety and efficacy immediately after stenting and at follow-up.</p></div>","PeriodicalId":94155,"journal":{"name":"Neurologia","volume":"38 8","pages":"Pages 521-529"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41173532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}