Neonatology最新文献_第10页

Skin Transillumination Improves Peripheral Vein Cannulation by Residents in Neonates: A Randomized Controlled Trial. 皮肤透照可改善住院医师为新生儿进行外周静脉插管的效果：随机对照试验

Neonatology Pub Date : 2024-05-16 DOI: 10.1159/000538880

Samantha Hinterstein, Harald Ehrhardt, Klaus-Peter Zimmer, A. Windhorst, Judith Kappesser, Christiane Hermann, Rahel Schuler, Markus Waitz

{"title":"Skin Transillumination Improves Peripheral Vein Cannulation by Residents in Neonates: A Randomized Controlled Trial.","authors":"Samantha Hinterstein, Harald Ehrhardt, Klaus-Peter Zimmer, A. Windhorst, Judith Kappesser, Christiane Hermann, Rahel Schuler, Markus Waitz","doi":"10.1159/000538880","DOIUrl":"https://doi.org/10.1159/000538880","url":null,"abstract":"INTRODUCTION\u0000Establishing peripheral vein access is challenging for pediatric residents and a painful procedure for neonates. We assessed the efficacy of a red light-emitting diode transilluminator during peripheral vein catheter insertion performed by pediatric residents.\u0000\u0000\u0000METHODS\u0000Patients were stratified by current weight (≤1,500 g, >1,500 g) and randomized to the transillumination or the control group. The first three attempts were performed by pediatric residents, followed by three attempts by a neonatologist. The primary outcome was success at first attempt. Secondary comparisons included time to successful insertion and overall success rates of residents and neonatologists.\u0000\u0000\u0000RESULTS\u0000A total of 559 procedures were analyzed. The success rate at resident's first attempt was 44/93 (47%) with transillumination versus 44/90 (49%) without transillumination (p = 0.88) in the strata ≤1,500 g and 103/188 (55%) with transillumination versus 64/188 (34%) without transillumination in the strata >1,500 g (p < 0.001). The overall success rate for residents was 86% in the transillumination versus 73% in the control group in the strata >1,500 g (p = 0.003) but not different in the strata ≤1,500 g (78/93 [84%] vs. 72/90 [80%], p = 0.57). There was no effect when the experience level of residents exceeded 6 months. Neonatologists' overall success rate and time to successful cannulation did not differ significantly in both weight strata.\u0000\u0000\u0000CONCLUSION\u0000Transillumination improves the first-attempt success rate of peripheral vein cannulation performed by pediatric residents in neonates >1,500 g, while no benefit was found in infants ≤1,500 g.","PeriodicalId":94152,"journal":{"name":"Neonatology","volume":"30 38","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140966369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Erratum. 勘误。

Neonatology Pub Date : 2024-05-16 DOI: 10.1159/000539078

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Erratum. 勘误。

Neonatology Pub Date : 2024-04-22 DOI: 10.1159/000538725

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Erratum. 勘误。

Neonatology Pub Date : 2024-04-22 DOI: 10.1159/000538838

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Severe Bronchopulmonary Dysplasia Adversely Affects Brain Growth in Preterm Infants. 严重支气管肺发育不良对早产儿脑部发育有不利影响

Neonatology Pub Date : 2024-04-22 DOI: 10.1159/000538527

Taiki Shimotsuma, Seiichi Tomotaki, Mitsuyo Akita, Ryosuke Araki, Hiroko Tomotaki, Kougoro Iwanaga, Akira Kobayashi, Akihiko Saitoh, Yasutaka Fushimi, Junko Takita, Masahiko Kawai

{"title":"Severe Bronchopulmonary Dysplasia Adversely Affects Brain Growth in Preterm Infants.","authors":"Taiki Shimotsuma, Seiichi Tomotaki, Mitsuyo Akita, Ryosuke Araki, Hiroko Tomotaki, Kougoro Iwanaga, Akira Kobayashi, Akihiko Saitoh, Yasutaka Fushimi, Junko Takita, Masahiko Kawai","doi":"10.1159/000538527","DOIUrl":"https://doi.org/10.1159/000538527","url":null,"abstract":"INTRODUCTION\u0000Bronchopulmonary dysplasia (BPD) is associated with neurodevelopmental outcomes of preterm infants, but its effect on brain growth in preterm infants after the neonatal period is unknown. This study aimed to evaluate the effect of severe BPD on brain growth of preterm infants from term to 18 months of corrected age (CA).\u0000\u0000\u0000METHODS\u0000Sixty-three preterm infants (42 with severe BPD and 21 without severe BPD) who underwent magnetic resonance imaging at term equivalent age (TEA) and 18 months of CA were studied by using the Infant Brain Extraction and Analysis Toolbox (iBEAT). We measured segmented brain volumes and compared brain volume and brain growth velocity between the severe BPD group and the non-severe BPD group.\u0000\u0000\u0000RESULTS\u0000There was no significant difference in brain volumes at TEA between the groups. However, the brain volumes of the total brain and cerebral white matter in the severe BPD group were significantly smaller than those in the non-severe BPD group at 18 months of CA. The brain growth velocities from TEA to 18 months of CA in the total brain, cerebral cortex, and cerebral white matter in the severe BPD group were lower than those in the non-severe BPD group.\u0000\u0000\u0000CONCLUSION\u0000Brain growth in preterm infants with severe BPD from TEA age to 18 months of CA is less than that in preterm infants without severe BPD.","PeriodicalId":94152,"journal":{"name":"Neonatology","volume":"39 23","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140676011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Erratum. 勘误。

Neonatology Pub Date : 2024-04-18 DOI: 10.1159/000538869

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Relationship between Neonatal Cerebral Fuels and Neurosensory Outcomes at 3 Years in Well Babies: Follow-Up of the Glucose in Well Babies (GLOW) Study. 健康婴儿 3 岁时新生儿脑燃料与神经感觉结果之间的关系：健康婴儿葡萄糖（GLOW）研究的后续研究。

Neonatology Pub Date : 2024-04-17 DOI: 10.1159/000538377

Deborah L Harris, Philip J Weston, G. Gamble, Jane E Harding

{"title":"Relationship between Neonatal Cerebral Fuels and Neurosensory Outcomes at 3 Years in Well Babies: Follow-Up of the Glucose in Well Babies (GLOW) Study.","authors":"Deborah L Harris, Philip J Weston, G. Gamble, Jane E Harding","doi":"10.1159/000538377","DOIUrl":"https://doi.org/10.1159/000538377","url":null,"abstract":"INTRODUCTION\u0000We sought to investigate if the availability of cerebral fuels soon after birth in healthy term babies was associated with developmental progress at 3 years of age.\u0000\u0000\u0000METHODS\u0000Healthy term babies had plasma glucose, lactate, and beta-hydroxybutyrate concentrations measured over the first 5 days. At 3 years, parents completed Ages and Stages (ASQ-3) questionnaires between December 2018 and August 2022. Developmental progress, analysed using structural equation modelling, was compared between children whose median fuel concentrations were above and below the mean neonatal concentrations of glucose (3.3 mmol/L) and total ATP-equivalents (140 mmol/L) in the first 48 h and over the first 5 days.\u0000\u0000\u0000RESULTS\u0000Sixty-four (96%) families returned completed questionnaires. We found no differences between developmental progress in children who had median neonatal plasma glucose concentrations <3.3 or ≥3.3 mmol/L in the first 48 h (estimated mean difference in ASQ scores -1.0, 95% confidence interval: -5.8, 3.7, p = 0.66) or 120 h (-3.7, -12.0, 4.6, p = 0.39]). There were also no differences for any other measures of cerebral fuels including total ATP above and below the median over 48 and 120 h, any plasma or interstitial glucose concentration <2.6 mmol/L, or cumulative duration of interstitial glucose concentration <2.6 mmol/L.\u0000\u0000\u0000CONCLUSIONS\u0000There was no detectable relationship between plasma concentrations of glucose, lactate, and beta-hydroxybutyrate soon after birth in healthy term babies and developmental progress at 3 years of age.","PeriodicalId":94152,"journal":{"name":"Neonatology","volume":" 22","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140691670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Mortality Risk in US Neonatal Intensive Care Unit Infants by Birth Size Classifications Comparing Three Growth Curves. 美国新生儿重症监护室婴儿按出生体型分类的死亡率风险，比较三种生长曲线。

Neonatology Pub Date : 2024-04-15 DOI: 10.1159/000536180

A. N. Ferguson, Marion Granger, I. Olsen, Reese H Clark, Jessica G Woo

{"title":"Mortality Risk in US Neonatal Intensive Care Unit Infants by Birth Size Classifications Comparing Three Growth Curves.","authors":"A. N. Ferguson, Marion Granger, I. Olsen, Reese H Clark, Jessica G Woo","doi":"10.1159/000536180","DOIUrl":"https://doi.org/10.1159/000536180","url":null,"abstract":"INTRODUCTION\u0000Three widely referenced growth curves classify infant birth anthropometric measurements as small (SGA), appropriate (AGA), or large (LGA) for gestational age (GA) differently. We assessed how these differences in assignment affect the identification and prediction of neonatal intensive care unit (NICU) mortality risk in US preterm infants.\u0000\u0000\u0000METHODS\u0000Birth data of infants admitted to NICUs from the Pediatrix Clinical Data Warehouse (2013-2018) were analyzed. Birth weight, length, and head circumference of 46,724 singleton infants (24-32 weeks GA) were classified as SGA, AGA, or LGA using the Olsen, Fenton, and INTERGROWTH-21st curves. NICU mortality risk based on birth size classification was analyzed using unadjusted and adjusted logistic regression stratified by GA.\u0000\u0000\u0000RESULTS\u0000Odds of mortality were increased with SGA classification at all GAs, size measurements, and curve sets, compared with AGA infants. LGA classification for weight was associated with lower mortality risk at 24 weeks GA and higher risk at 30 weeks GA. Odds of mortality did not differ significantly across curve sets. Classification of size at birth alone had relatively low predictive ability to identify mortality risk, with unadjusted AUCs near 0.5 for all analyses.\u0000\u0000\u0000CONCLUSION\u0000There were no significant differences across curve sets in predicting mortality. Classification of size at birth is a relatively imprecise method to identify infants at risk for NICU mortality.","PeriodicalId":94152,"journal":{"name":"Neonatology","volume":"57 12","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140700324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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LISA Eligibility and LISA Success in Extremely Preterm Infants: A Single-Center Experience. 极早产儿的 LISA 资格和 LISA 成功率：单中心经验

Neonatology Pub Date : 2024-04-10 DOI: 10.1159/000537904

Ruth Klein, Laura Fastnacht, Angela Kribs, Benjamin Kuehne, K. Mehler

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Proactive Diagnosis and Tailor-Made Treatment of Patent Ductus Arteriosus in Very Preterm Infants with Routine Echocardiography in Japan: A post hoc Analysis of the PLASE Study. 日本常规超声心动图对早产儿动脉导管未闭的主动诊断和定制治疗：PLASE 研究的事后分析。

Neonatology Pub Date : 2024-04-09 DOI: 10.1159/000538363

Seiichi Tomotaki, Tetsuya Isayama, Tohru Kobayashi, Satoshi Masutani, Hidenori Kawasaki, Atsushi Nakayama, Toshifumi Ikeda, K. Toyoshima

{"title":"Proactive Diagnosis and Tailor-Made Treatment of Patent Ductus Arteriosus in Very Preterm Infants with Routine Echocardiography in Japan: A post hoc Analysis of the PLASE Study.","authors":"Seiichi Tomotaki, Tetsuya Isayama, Tohru Kobayashi, Satoshi Masutani, Hidenori Kawasaki, Atsushi Nakayama, Toshifumi Ikeda, K. Toyoshima","doi":"10.1159/000538363","DOIUrl":"https://doi.org/10.1159/000538363","url":null,"abstract":"INTRODUCTION\u0000A feature of the management of extremely preterm infants in Japan is proactive circulatory management using early routine echocardiography performed by neonatologists.\u0000\u0000\u0000METHODS\u0000This study was a post hoc analysis of the Patent ductus arteriosus and Left Atrial Size Evaluation in preterm infants (PLASE) study, which is a prospective cohort study including preterm infants admitted to 34 tertiary neonatal intensive care units in Japan between October 2015 and December 2016. We described the details of the treatment strategy of patent ductus arteriosus (PDA) based on early routine echocardiography.\u0000\u0000\u0000RESULTS\u0000In total, 613 preterm infants were included into the analysis. Twenty percent of infants with prophylactic indomethacin were switched to therapeutic cyclooxygenase inhibitor (COX-I) before the completion of the full prophylactic indomethacin course. Therapeutic COX-I was mostly administered based on echocardiographic findings before PDA became symptomatic or hemodynamically significant. Therapeutic COX-I was frequently discontinued after one or two doses before the full course (three doses) was completed. The proportion of infants requiring additional treatment (additional therapeutic COX-I course or surgical PDA closure) after discontinued COX-I courses (<3 doses) compared to infants after completed 3 doses course was significantly lower (after the first therapeutic COX-I course 46% vs. 68%, p < 0.001) or without a significant difference (after the second or third course).\u0000\u0000\u0000CONCLUSIONS\u0000The clinical management of PDA in Japan featured (1) COX-I administration based on echocardiographic findings before symptomatic or hemodynamically significant PDA appeared and (2) frequent discontinuation of therapeutic COX-I before completing the standard three doses course.","PeriodicalId":94152,"journal":{"name":"Neonatology","volume":"30 6","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140725366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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