Journal of the Chinese Medical Association : JCMA最新文献

{"title":"Association between vitamin D and COVID-19 infection and mortality in Taiwanese patients.","authors":"Ching-Ching Sheng, Shuan-Yi Su, Ying Liang, Hui-Chuan Cheng, Hsin-Yi Huang, Hsiao-Hui Chiu","doi":"10.1097/JCMA.0000000000001294","DOIUrl":"https://doi.org/10.1097/JCMA.0000000000001294","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D plays a role in immune regulation and may influence COVID-19 outcomes. This study examined the association between serum vitamin D levels with COVID-19 infection and mortality in symptomatic patients in Taiwan.</p><p><strong>Methods: </strong>This retrospective cohort study included symptomatic patients who underwent COVID-19 real-time polymerase chain reaction (RT-PCR) assay between 2020 and 2023. Serum 25-hydroxyvitamin D (25(OH)D) levels were categorized as deficient (<20 ng/mL), insufficient (20-30 ng/mL), or sufficient (≥30 ng/mL). Logistic regression models were used to evaluate the impact of vitamin D levels on COVID-19 infection and mortality, adjusting for potential confounders including age, sex, and comorbidities.</p><p><strong>Results: </strong>Among the 481 participants (mean age 58.2 years; 66.7% female), 96 (19.96%) tested positive for COVID-19. Vitamin D level was not associated with COVID-19 infection (OR=1.00, 95% CI: 0.99-1.02, p=0.687), however vitamin D deficiency significantly increased the risk of COVID-19-related mortality (OR=10.68, 95% CI: 1.18-96.45; p=0.035). The mortality rate in patients aged 65-74 years was higher compared to those aged 19-44 years (OR=12.91, 95% CI: 1.29-128.83; p=0.029).</p><p><strong>Conclusions: </strong>Vitamin D levels were not associated with susceptibility to COVID-19 infection. However, vitamin D deficiency, particularly in older patients, was associated with an increased risk of mortality among those diagnosed with COVID-19. These findings support the role of vitamin D in reducing COVID-19 mortality, and emphasize the importance of maintaining sufficient levels in high-risk populations.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PM2.5 exposure induces transcriptomic changes in ARPE-19 cells with activation of TGFβ-mediated signaling pathways: A next-generation sequencing approach.","authors":"Chueh-Tan Chen, Zhi-Hu Lin, Tung-Yi Lin, Yi-An Lin, Hsin Yeh, Wei-Jyun Hua, Ching-Yao Tsai","doi":"10.1097/JCMA.0000000000001295","DOIUrl":"https://doi.org/10.1097/JCMA.0000000000001295","url":null,"abstract":"<p><strong>Background: </strong>Ambient fine particulate matter (PM2.5) has emerged as a critical environmental threat to ocular health; however, the underlying molecular mechanisms affecting the retinal pigment epithelium (RPE) remain largely uncharacterized. This study aimed to investigate transcriptomic alterations in RPE cells following PM2.5 exposure and to identify key regulatory pathways involved.</p><p><strong>Methods: </strong>Next-generation sequencing (NGS) was used to investigate differential gene expression in ARPE-19 cells upon PM2.5 exposure. Bioinformatic analyses, including pathway enrichment and gene set enrichment analysis (GSEA), were performed to identify affected signaling cascades. Functional assays-including cell viability, wound healing, and Transwell migration-were conducted to evaluate phenotypic changes. Quantitative RT-PCR and ELISA validated gene expression and transforming growth factor-beta (TGFβ) secretion. TGFβ stimulation and receptor inhibition were applied to dissect pathway involvement.</p><p><strong>Results: </strong>Comprehensive analysis revealed substantial changes in gene expression profiles, with pathway enrichment highlighting the activation of cell migration-related pathways such as focal adhesion, regulation of actin cytoskeleton, ECM-receptor interaction, tight junction, and adherens junction. Notably, the TGFβ, MAPK, and PI3K/AKT pathways were significantly modulated. Functional assays showed that PM2.5 exposure enhanced ARPE-19 cell viability and migratory capacity. Among the differentially expressed genes, angiopoietin-like 4 (ANGPTL4) was markedly upregulated following PM2.5 stimulation. Pharmacological inhibition of TGFβ signaling abrogated PM2.5-induced ANGPTL4 expression, suggesting a pivotal role of the TGFβ pathway in mediating these effects.</p><p><strong>Conclusion: </strong>These findings demonstrate that PM2.5 induces transcriptomic reprogramming and activates the TGFβ signaling cascade in RPE cells, thereby enhancing cellular migration. Specifically, ANGPTL4 was identified as a key downstream effector of this pathway. This study provides novel insights into the molecular mechanisms by which air pollution contributes to retinal disease pathogenesis and suggests potential therapeutic targets for preventing PM2.5-induced retinal injury.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac magnetic resonance parameters for prognostic stratification in pulmonary hypertension: A longitudinal study.","authors":"Fei-Ran Chiou, Shih-Hsien Sung, Jui-Han Chiu, Chao-Yu Guo, Ying-Chi Lee, Ying-Yueh Chang, Ching-Yao Weng, Yi-Jui Hsu, Chun-Ku Chen","doi":"10.1097/JCMA.0000000000001292","DOIUrl":"https://doi.org/10.1097/JCMA.0000000000001292","url":null,"abstract":"<p><strong>Background: </strong>Cardiac magnetic resonance (CMR) imaging is a critical tool for the diagnosis and evaluation of pulmonary hypertension (PH). This study aimed to investigate the temporal changes in cardiac morphological and functional characteristics in PH using CMR, with the goal of identifying early indicators of adverse clinical outcomes.</p><p><strong>Methods: </strong>This retrospective study included patients diagnosed with PH using right heart catheterization. Each patient underwent two CMR sessions, approximately 1.5 years apart, for follow-up. CMR characteristics, including morphological and functional parameters such as myocardial strain, were analyzed in relation to the primary adverse events endpoint, defined as a composite of heart failure hospitalization and all-cause mortality.</p><p><strong>Results: </strong>A total of 36 patients (8 men and 28 women, mean age 48.0±13.3 years) were enrolled. Eleven patients (30.6%) experienced adverse events after the second CMR. High right ventricular (RV) volume and worse RV strain at follow-up were observed in patients who experienced future events (RV end-diastolic volume [RVEDV], 247.2 mL vs. 182.3 mL, p = 0.029; and right ventricular global longitudinal strain [RVGLS], -12.0% vs. -17.1%, p = 0.021, respectively). In contrast, an increase in left ventricular ejection fraction (LVEF) and left ventricular (LV) volume was noted in patients without events, whereas a decrease in LV end-diastolic volume was associated with subsequent events (111.6 mL vs. 123.9 mL, p = 0.024). An increase in LVEF was observed in patients without events (61.5% vs. 57.3%, p = 0.030), underscoring the predictive value of LV function.</p><p><strong>Conclusion: </strong>This study emphasizes the value of CMR in monitoring patients with PH, particularly for assessing ventricular function as a predictor of future outcomes. The observed trends in myocardial strain highlight its potential as a prognostic marker, warranting further research to confirm its clinical utility.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The trend of utilizing de-escalation of surgical extent for treating early-stage cervical cancer patients.","authors":"Szu-Ting Yang, Peng-Hui Wang, Chia-Hao Liu","doi":"10.1097/JCMA.0000000000001272","DOIUrl":"10.1097/JCMA.0000000000001272","url":null,"abstract":"","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":"657-659"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of ulnar fracture level on radial head dislocation: A Monteggia fracture study.","authors":"Kuan-Yu Huang, Chun-Yu Chen, Kai-Cheng Lin","doi":"10.1097/JCMA.0000000000001276","DOIUrl":"10.1097/JCMA.0000000000001276","url":null,"abstract":"<p><strong>Background: </strong>Monteggia fracture is defined as a combination of a proximal ulnar fracture with radial head dislocation. Radial head dislocation may be misdiagnosed under an elbow radiograph, leading to further complications. This study aimed to compare the ulnar fracture pattern characteristics between Monteggia fracture and an isolated proximal ulnar fracture in terms of how close the fracture site is to the coronoid and what type of fracture pattern is more likely to result in radial head dislocation.</p><p><strong>Methods: </strong>This single-center retrospective study, conducted from January 2014 to June 2022, included adult patients with proximal to midshaft ulnar fractures, excluding nonacute trauma, revision surgeries, and intra-articular fractures. All patients underwent anteroposterior (AP) and lateral elbow radiographs and forearm radiograph. Fracture patterns and injury mechanisms were recorded for analysis.</p><p><strong>Results: </strong>We included 51 patients in this study. The mean age was 38.5 ± 16.1 years, and 70.1% were men (n = 36). Monteggia fractures were classified according to the Bado classification into type I (n = 5), type II (n = 7), type III (n = 8), and type IV (n = 0). Traffic accidents comprised 63% of the injuries (n = 32), and 45% were oblique type ulnar fractures (n = 23). Monteggia fracture and proximal ulnar fracture presented with mean distance from coronoid tip to fracture of 6.12 ± 2.32 cm and 9.00 ± 3.00 cm ( p < 0.01). As per the receiver operating characteristic curve (ROC), the distance from coronoid tip to fracture of 7.33 cm had the highest area under the curve (AUC) value (0.807). Angulations of Monteggia fracture and isolated ulnar fracture were 24.02° ± 12.10° and 10.77° ± 8.10° ( p < 0.01). However, there were no differences in the length of the fracture line between two groups.</p><p><strong>Conclusion: </strong>The distance from coronoid tip to fracture within 7.3 cm is more likely to cause a Monteggia fracture than an isolated proximal ulnar fracture. Otherwise, a Monteggia fracture is prone to more severe angulation.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":"686-691"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144746663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic challenges of pancreatic carcinoma presenting as acute pancreatitis: A case series and literature review.","authors":"Chih-Kai Huang, Hsuan-Hung Yu, Ching-Ming Kwok, Ming-Zhang Sung, Ming-Hsun Yang, Chuan-Hsun Chang, Chi-Ming Liu, Gar-Yang Chau, Cheng-Hsi Su","doi":"10.1097/JCMA.0000000000001274","DOIUrl":"10.1097/JCMA.0000000000001274","url":null,"abstract":"<p><strong>Background: </strong>Pancreatic cancer can be challenging to diagnose, particularly when it presents with features resembling pancreatitis. Misdiagnosis can delay treatment and adversely affect patient outcomes. This case series highlights the diagnostic difficulties and clinical outcomes in patients initially diagnosed with pancreatitis, who were later found to have pancreatic malignancies such as pancreatic ductal adenocarcinoma (PDAC).</p><p><strong>Methods: </strong>We reviewed the medical records of patients who underwent pancreatic-related procedures from 2011 to 2024 at a tertiary care hospital in Taiwan.</p><p><strong>Results: </strong>The review identified 70 patients with resectable pancreatic malignancies, of whom 18 (26%) had a diagnosis of pancreatitis before their cancer was diagnosed. Four cases were selected for detailed presentation, highlighting the potential for missed or delayed pancreatic cancer diagnoses in patients with recurrent pancreatitis. Upon further investigation, we found that subtle signs of malignancy are often masked on initial imaging studies, leading to delays in definitive diagnosis and treatment.</p><p><strong>Conclusion: </strong>This case series demonstrates the complexities in diagnosing pancreatic cancer, particularly when the presentation is that of pancreatitis. Our findings emphasize the need for careful review of imaging results and a high clinical suspicion of malignancy in patients with recurrent pancreatitis. Further research into more effective diagnostic tools and treatment strategies is warranted to enhance the early detection and management of pancreatic cancer in similar clinical scenarios.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":"701-708"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144736435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival outcome of airway stenting in patients with esophageal cancer with airway involvement.","authors":"Chung-Yun Kuan, Chia Liu, Yi-Ying Lee, Hung-Che Chien, Jung-Jyh Hung, Chien-Sheng Huang, Han-Shui Hsu, Po-Kuei Hsu","doi":"10.1097/JCMA.0000000000001271","DOIUrl":"10.1097/JCMA.0000000000001271","url":null,"abstract":"<p><strong>Background: </strong>Airway stenting in patients with esophageal cancer involving the airway possibly improves survival by relieving the symptoms of obstructive pneumonitis and facilitating cancer treatment. However, its advantages over conservative management remain unclear. Therefore, we compared the survival outcomes of airway stenting and conservative treatment in patients with advanced esophageal cancer.</p><p><strong>Methods: </strong>We retrospectively reviewed patients with advanced esophageal cancer involving the airway who were treated at Taipei Veterans General Hospital between July 2005 and January 2023. Airway involvement included airway obstruction with obstructive symptoms or esophago-respiratory fistulas. Patients were categorized into the stent and conservative treatment groups. We compared patients' clinical characteristics, post-airway involvement survival (PAIS), and overall survival (OS) and assessed the prognostic factors for survival.</p><p><strong>Results: </strong>A total of 52 patients, including 31 with airway stenting and 21 with conservative treatment, were included. No differences were observed between the two treatment groups in terms of age, sex, body mass index, clinical performance (Eastern Cooperative Oncology Group [ECOG]), tumor location, clinical N stage, or site of airway involvement. However, the conservative treatment group had more patients with clinical T4 stage ( p < 0.001) and M1 stage ( p = 0.04) than did the stent group. PAIS (117 vs 43 days; p = 0.02) and OS (351 vs 106 days; p < 0.001) were significantly longer in the stent group than in the conservative treatment group. In addition, airway stenting significantly reduced pneumonia-related mortality (9.7% vs 52.4%; p = 0.001). Multivariable analysis revealed anticancer treatment after airway involvement (hazard ratio [HR], 0.13; confidence interval [CI], 0.06-0.27; p < 0.001) and airway stenting (HR, 0.37; CI, 0.20-0.68; p = 0.001) as significant prognostic factors for PAIS. For OS, ECOG ≥1 (HR, 2.20; CI, 1.09-4.42; p = 0.03) and airway stenting (HR, 0.37; CI, 0.17-0.78; p = 0.01) were significant prognostic factors.</p><p><strong>Conclusion: </strong>Airway stenting reduced pneumonia-related mortality in patients with advanced esophageal cancer with airway involvement. Moreover, patients who underwent airway stenting had better survival than did those who received conservative treatment alone; thus, airway stenting should be recommended after careful patient selection.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":"692-700"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bibliographic analysis of Taiwanese publications in the Web of Science Respiratory System Category from 1972 to 2023.","authors":"Ying-Hsuan Hwang, Chih-Teng Chiang, Yuh-Min Chen, I-Hsuan Hwang, Chun-Feng Huang, Yu-Chun Chen, Shinn-Jang Hwang","doi":"10.1097/JCMA.0000000000001275","DOIUrl":"10.1097/JCMA.0000000000001275","url":null,"abstract":"<p><strong>Background: </strong>Academic publications are important for developing medical specialties. Respiratory system diseases are among the most common human diseases and have a significant impact on morbidity and mortality. This is particularly true regarding the impact of the new coronavirus, severe acute respiratory syndrome coronavirus 2. This study aimed to perform a bibliographic analysis of Taiwanese academic publications in the Web of Science (WoS) subject category of respiratory systems.</p><p><strong>Methods: </strong>Publications in the WoS Respiratory System Category, including papers in Science Citation Index Expanded and Social Sciences Citation Index journals from 1972 to 2023, were retrieved and analyzed.</p><p><strong>Results: </strong>Among 392 030 papers published worldwide in the WoS Respiratory System Category from 1972 to 2023, 3672 (0.94%) were published in Taiwan, ranking 21st in the world, with a total of 82 956 citations. Over these five decades, the annual number of Taiwanese publications and citations has increased over time. However, the mean impact factor of publications has shown a tendency to decrease since 1997. International collaboration with coauthors outside Taiwan was found in 780 papers (21.24% of the total publications), mainly from the United States, the People's Republic of China, the United Kingdom, France, and South Korea. Collaborative papers had a significantly higher mean impact factor (8.2 ± 0.3 vs 5.6 ± 0.1, p < 0.001) and citation counts per paper (44.2 ± 3.3 vs 25.2 ± 0.8, p < 0.001) than those of non-collaborative papers.</p><p><strong>Conclusion: </strong>Taiwanese publications in the WoS Respiratory System Category have a trend of increasing number and citations since 1972. However, the mean impact factor of the published papers has decreased since 1997. This disproportionate trend is an observational finding that deserves further investigation.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":"709-716"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144746662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ReDuNing inhibits alveolar macrophage inflammation in LPS mice by activating JAK1/STAT3.","authors":"Fan Ye, Xing Li, Jia-Long Zhang, Zhong-Qian Lu, Yu-Xuan Duan, Shan-Shan Hou, Yi-Jun Deng","doi":"10.1097/JCMA.0000000000001270","DOIUrl":"10.1097/JCMA.0000000000001270","url":null,"abstract":"<p><strong>Background: </strong>The traditional Chinese medicine ReDuNing (RDN) is primarily composed of Artemisia annua , Gardenia jasminoides , Lonicera japonica , and clinically utilized for treating influenza. Therefore, we explored the mechanism of RDN in sepsis-induced lung injury.</p><p><strong>Methods: </strong>Network pharmacology was used to identify the active components of RDN. A drug component network was constructed using Cytoscape 3.10.1 to identify key compounds, and a protein‒protein interaction (PPI) network was established using the STRING database. Common targets of RDN and sepsis were uploaded to the DAVID Bioinformatics Resources 6.8 for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses to predict potential signaling pathways. In vitro, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blot assays were used to detect the expression levels of JAK1/STAT3 and inflammatory factors. Subsequently, in vivo experiments were performed to validate these hypotheses.</p><p><strong>Results: </strong>JAK1 was the most significantly enriched common target, and RDN may exert its effects via the JAK1/STAT3 signaling pathway. The expression of proinflammatory cytokines decreased in RDN-treated MH-S cells, which increased after inhibiting the JAK1/STAT3 pathway. The in vivo experimental results confirmed the in vitro findings.</p><p><strong>Conclusion: </strong>RDN regulates the secretion of inflammatory cytokines by alveolar macrophages by activating the JAK1/STAT3 pathway, thereby alleviating sepsis-induced acute lung injury.</p>","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":"717-725"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The frontline of metabolic dysfunction-associated steatotic liver disease: More to be discovered.","authors":"Chun-Ting Ho, Wei-Yu Kao, Chien-Wei Su","doi":"10.1097/JCMA.0000000000001266","DOIUrl":"10.1097/JCMA.0000000000001266","url":null,"abstract":"","PeriodicalId":94115,"journal":{"name":"Journal of the Chinese Medical Association : JCMA","volume":" ","pages":"660-661"},"PeriodicalIF":2.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}