Daniel A Lorenzatti, Annalisa Filtz, Pamela Piña, Jeirym Miranda, Siddarth Ragupathi, Felipe Contreras Yametti, Andrea Scotti, Winsome Elliott-Bailey, João L Cavalcante, Thomas Ivanc, Azeem Latib, Mario J Garcia, Leandro Slipczuk
{"title":"Comparison of dual-energy iodine and standard subtraction methods for myocardial extracellular volume quantification using cardiac computed tomography.","authors":"Daniel A Lorenzatti, Annalisa Filtz, Pamela Piña, Jeirym Miranda, Siddarth Ragupathi, Felipe Contreras Yametti, Andrea Scotti, Winsome Elliott-Bailey, João L Cavalcante, Thomas Ivanc, Azeem Latib, Mario J Garcia, Leandro Slipczuk","doi":"10.1016/j.jcct.2025.03.009","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.03.009","url":null,"abstract":"<p><strong>Background: </strong>Computed tomography (CT)-derived extracellular volume fraction (ECV) quantifies myocardial fibrosis noninvasively, comparable to cardiovascular magnetic resonance. The conventional subtraction method (ECV-conv) requires dedicated pre- and post-contrast acquisitions, while the dual-energy spectral method (ECV-spec) uses only the post-contrast phase. We aimed to compare these methods in patients undergoing CT planning for transcatheter aortic valve replacement (TAVR).</p><p><strong>Methods: </strong>We prospectively included patients undergoing CT-TAVR evaluation on a dual-energy dual-layer detector scanner. Baseline pre-contrast and equilibrium delay phase (at 5 min) prospectively ECG-triggered acquisitions were co-registered for ECV-conv calculation. Equilibrium phase spectral iodine maps were derived for ECV-spec measurement and compared with ECV-con maps using a mid-septal and a global mid-ventricular region of interest.</p><p><strong>Results: </strong>Overall, 78 patients (53 % female, mean age 77 years) were analyzed. There was a minor overestimation in global measurement by ECV-spec (31.8 ± 4.6 % vs 30.3 ± 5.3 %, p = 0.023. However, there were no significant differences between both methods for the mid-septal measurement (ECV-conv = 30.4 ± 5.3 % vs ECV-spec = 31.0 ± 5.6 %, p = 0.196).). Both methods demonstrated comparable 95 % limits of agreement, with a strong correlation for mid-septal (r = 0.75, p < 0.0001) and a moderate correlation for global measurements (r = 0.51, p < 0.0001).</p><p><strong>Conclusions: </strong>Myocardial CT-ECV estimation using dual-energy spectral maps was comparable to the conventional subtraction method without the need of a pre-contrast acquisition. This approach may help reduce imaging and processing times, as well as minimize radiation exposure.</p>","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor re: Racial bias in CCT article.","authors":"Vinoda Sharma, Derek Connolly","doi":"10.1016/j.jcct.2025.03.012","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.03.012","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel O'Meara, Arene Butto, James A Kuo, Fawwaz Shaw, Ritu Sachdeva, Susan Taylor, Sassan Hashemi, Hunter C Wilson
{"title":"Aortic dissection after heart transplantation for early Fontan failure: A rare complication.","authors":"Daniel O'Meara, Arene Butto, James A Kuo, Fawwaz Shaw, Ritu Sachdeva, Susan Taylor, Sassan Hashemi, Hunter C Wilson","doi":"10.1016/j.jcct.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.03.011","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juan Manuel Monteagudo Ruiz, Pablo Martínez-Vives, Irene Carrión-Sánchez, Cristina García-Sebastián, Eduardo Casas Rojo, Álvaro Arribas Marcos, Jose Luis Zamorano, Covadonga Fernández-Golfin
{"title":"Accuracy of coronary CTA using spectral CT in patients with high calcium score.","authors":"Juan Manuel Monteagudo Ruiz, Pablo Martínez-Vives, Irene Carrión-Sánchez, Cristina García-Sebastián, Eduardo Casas Rojo, Álvaro Arribas Marcos, Jose Luis Zamorano, Covadonga Fernández-Golfin","doi":"10.1016/j.jcct.2025.03.005","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.03.005","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunil J Ghelani, Prachi P Agarwal, Spencer B Barfuss, Anjali Chelliah, Jennifer Cohen, Anthony M Hlavacek, Tarique Hussain, Angela M Kelle, Rajesh Krishnamurthy, Yue-Hin Loke, Shiraz A Maskatia, Laura J Olivieri, Ashwin Prakash, Hari G Rajagopal, Cynthia K Rigsby, Joshua D Robinson, Timothy C Slesnick, B Kelly Han
{"title":"Rapid growth of CT utilization compared to MRI and echocardiography in imaging for congenital heart disease: A multicenter analysis.","authors":"Sunil J Ghelani, Prachi P Agarwal, Spencer B Barfuss, Anjali Chelliah, Jennifer Cohen, Anthony M Hlavacek, Tarique Hussain, Angela M Kelle, Rajesh Krishnamurthy, Yue-Hin Loke, Shiraz A Maskatia, Laura J Olivieri, Ashwin Prakash, Hari G Rajagopal, Cynthia K Rigsby, Joshua D Robinson, Timothy C Slesnick, B Kelly Han","doi":"10.1016/j.jcct.2025.02.005","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.02.005","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Lorenzatti, Annalisa Filtz, Jolien Geers, Kajetan Grodecki, Vita Jaspan, Colin Pierce, Matthew J Miller, Christine Park, Alexandrina Danilov, Ron Blankstein, Thomas A Treibel, João L Cavalcante, Leslee J Shaw, Marc R Dweck, Piotr J Slomka, Damini Dey, Leandro Slipczuk
{"title":"Novel CT-derived markers for enhanced long-term risk stratification in the planning of TAVR for aortic stenosis.","authors":"Daniel Lorenzatti, Annalisa Filtz, Jolien Geers, Kajetan Grodecki, Vita Jaspan, Colin Pierce, Matthew J Miller, Christine Park, Alexandrina Danilov, Ron Blankstein, Thomas A Treibel, João L Cavalcante, Leslee J Shaw, Marc R Dweck, Piotr J Slomka, Damini Dey, Leandro Slipczuk","doi":"10.1016/j.jcct.2025.01.008","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.01.008","url":null,"abstract":"<p><p>In an era of rapidly expanding use of transcatheter aortic valve replacement (TAVR), cardiovascular computed tomography (CCT) has become an essential component in the evaluation process for the growing number of patients. Because of the nature of the guideline-recommended protocol -involving several different CCT acquisitions-it represents a unique dataset for comprehensive phenotyping of the patient with significant aortic stenosis. A substantial body of data has established CCT as a central tool in pre-procedural implantation planning. However, emerging evidence suggests a potential new role for CCT in phenotyping patient risk beyond the index procedure. This new role could represent a unique opportunity in patient selection, medication optimization and follow up post TAVR aiming to improve long-term prognosis. This review highlights emerging data on CCT imaging features for risk stratification in patients during long-term follow-up after TAVR. We summarize the existing literature on this topic and explore whether comprehensive CCT-derived information could be integrated into clinical practice, potentially enhancing TAVR patient selection and post-procedural care.</p>","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143367109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surachai Kongrat, Daniel A Castellanos, Nao Sasaki, Stuart Lipsitz, David Schidlow, Rebecca Beroukhim, Rahul H Rathod, Ashwin Prakash, Sunil J Ghelani
{"title":"Comparison of cine cardiac CT and echocardiography for assessment of ventricular function late after the Fontan operation.","authors":"Surachai Kongrat, Daniel A Castellanos, Nao Sasaki, Stuart Lipsitz, David Schidlow, Rebecca Beroukhim, Rahul H Rathod, Ashwin Prakash, Sunil J Ghelani","doi":"10.1016/j.jcct.2025.01.006","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.01.006","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Kelly Han, Cynthia K Rigsby, Tarique Hussain, Anthony Hlavacek, Anjali Chelliah, Kanwal M Farooqi, Jennifer Cohen, Timothy Slesnick, Rajesh Krishnamurthy, Taylor Chung, Prachi P Agarwal, Ashwin Prakash, Sunil Ghelani, Aurelio Secinaro, Brian Ghoshhadra, Shazia Mohsin, Aloha Maeve, Mahesh Kappanayil, Renee P Bullock-Palmer, Cristina Fuss, James Shambrook, Thomas Semple, Angela M Kelle, Li San Lynette Teo, Lorna P Browne, Edward D Nicol
{"title":"Proposed resources required for a comprehensive program for CCT CHD imaging.","authors":"B Kelly Han, Cynthia K Rigsby, Tarique Hussain, Anthony Hlavacek, Anjali Chelliah, Kanwal M Farooqi, Jennifer Cohen, Timothy Slesnick, Rajesh Krishnamurthy, Taylor Chung, Prachi P Agarwal, Ashwin Prakash, Sunil Ghelani, Aurelio Secinaro, Brian Ghoshhadra, Shazia Mohsin, Aloha Maeve, Mahesh Kappanayil, Renee P Bullock-Palmer, Cristina Fuss, James Shambrook, Thomas Semple, Angela M Kelle, Li San Lynette Teo, Lorna P Browne, Edward D Nicol","doi":"10.1016/j.jcct.2025.01.003","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.01.003","url":null,"abstract":"<p><strong>Background: </strong>Cardiac Computed Tomography (CCT) is increasingly used for evaluation of congenital heart disease (CHD) in patients of all ages. Pediatric and adult congenital heart disease (ACHD) surgical programs require high quality CCT imaging as part of the multimodality imaging support expected of comprehensive care centers. Despite these expectations, there are no benchmarks or defined programmatic elements specific to the performance of CCT in patients with CHD. To address this deficit, this manuscript is written by a group of current CHD CCT practitioners and provides a collective opinion regarding the clinical components required, and essential resources needed, to deliver a comprehensive CCT CHD imaging program. Resource allocation was divided into CCT technology, imaging technologist, physician and programmatic support. The group is inclusive of pediatric and adult cardiologists and radiologists and includes practitioners from high and lower resourced programs and countries. Imaging settings are inclusive of academic and private practice, heart centers and combined radiology/cardiology service lines. Challenges and areas for future advocacy to support this growing specialty are proposed to improve performance standards that will consider the expected widespread variation in technical and staffing resources, skillsets, and practice settings for CT in CHD.</p><p><strong>Summary: </strong>High quality cardiovascular computed tomography is an essential component of pediatric and adult congenital programs and surgical centers. Program growth outpaces resource allocation in most institutions. This opinion paper outlines essential components for technical, technologist and physician resources and programmatic support to develop and maintain a successful CCT in CHD program. Although a small component of most cardiac imaging programs, it is an essential component particularly in complex cases. Institutional and imaging societal commitment is essential to support this emerging field at highest quality.</p>","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}