Hemodialysis international. International Symposium on Home Hemodialysis最新文献

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Developing and Evaluating a Home Hemodialysis Training Program-A Quality Improvement Study. 发展和评估家庭血液透析培训计划-质量改进研究。
Kristina K Knudsen, Carolina V Adrian, Mathilde H Jensen, Siw Ilsøe, Jeanett Rugaard, Selina Emilie Poulsen, Krista Dybtved Kjærgaard, Jeanette Finderup
{"title":"Developing and Evaluating a Home Hemodialysis Training Program-A Quality Improvement Study.","authors":"Kristina K Knudsen, Carolina V Adrian, Mathilde H Jensen, Siw Ilsøe, Jeanett Rugaard, Selina Emilie Poulsen, Krista Dybtved Kjærgaard, Jeanette Finderup","doi":"10.1111/hdi.13252","DOIUrl":"https://doi.org/10.1111/hdi.13252","url":null,"abstract":"<p><strong>Introduction: </strong>In 2018, our home hemodialysis training program required 3-4 months to complete, with sessions lasting 4 h, three times a week. Due to the time commitment, some patients who preferred home hemodialysis decided on alternative dialysis modalities. This study aimed to (1) identify potential improvements to Training Program 1.0, (2) develop Training Program 2.0, and (3) assess the outcomes of Training Program 2.0.</p><p><strong>Method: </strong>We reviewed literature, conducted focus groups with home hemodialysis nurses in Helsinki, Finland, and interviewed patients who participated in Training Program 1.0. Training Program 2.0 was developed in collaboration with patients and clinicians, using a \"learning by doing\" approach. Evaluation included both qualitative interviews and quantitative analysis of patient records.</p><p><strong>Findings: </strong>Patients' feedback, aligned with the literature and Helsinki's program, led to six major changes: (1) more frequent training sessions, (2) earlier introduction of self-cannulation, (3) a permanent team of training nurses, (4) a shorter and more structured program, (5) individualized weekly schedules, and (6) clearer instructions. Training frequency increased to four sessions per week, with self-cannulation introduced in the second week. The quantitative results showed a trend toward a reduction in the number of training sessions and total training time. The qualitative data indicated a marked improvement in patient experience.</p><p><strong>Discussion: </strong>The modifications in Training Program 2.0 created a more effective learning environment, as evidenced by improved patient satisfaction. While quantitative measures did not show significant reductions in training time, the qualitative improvements suggest that these changes positively impact the patient experience, aligning with findings from other home hemodialysis studies. These results underscore the importance of tailoring training programs to patient needs and preferences, contributing to better engagement and potentially higher adoption of home hemodialysis.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated Trimethylamine-N-oxide (TMAO) Is Associated with Vascular Access Dysfunction in Maintenance Hemodialysis Patients. 三甲胺- n -氧化物(TMAO)升高与维持性血液透析患者血管通路功能障碍有关
Yin Zheng, Yuan Ren, Li You, Junfeng Liu, Jun Xue
{"title":"Elevated Trimethylamine-N-oxide (TMAO) Is Associated with Vascular Access Dysfunction in Maintenance Hemodialysis Patients.","authors":"Yin Zheng, Yuan Ren, Li You, Junfeng Liu, Jun Xue","doi":"10.1111/hdi.13255","DOIUrl":"https://doi.org/10.1111/hdi.13255","url":null,"abstract":"<p><strong>Introduction: </strong>Elevated levels of trimethylamine-N-oxide (TMAO), a metabolite produced by gut microbiota, have been associated with cardiovascular diseases and complications in various populations. However, its role in vascular access dysfunction in hemodialysis patients remains underexplored. This study investigates the potential relationship between TMAO levels and vascular access dysfunction in maintenance hemodialysis patients.</p><p><strong>Methods: </strong>This study included 80 hemodialysis patients. The baseline serum TMAO levels were measured, and clinical characteristics and dialysis-related data were collected. They were followed up on vascular access dysfunction events over a period of 1 year. The association between serum TMAO levels and vascular access dysfunction events were investigated.</p><p><strong>Findings: </strong>In our cohort, we observed a wide distribution of serum concentrations, with a median concentration of 15.2 μmol/L and a maximum concentration of 245.3 μmol/L. Patients were stratified into a low-TMAO group and a high-TMAO group according to the median value of TMAO concentrations. Those in the high-TMAO group had a significantly higher incidence of vascular access dysfunction events (p = 0.023). TMAO was independently associated with vascular access dysfunction events after adjusting for some potential vascular access dysfunction risk factors.</p><p><strong>Discussion: </strong>This study suggests that elevated serum TMAO levels may serve as an independent risk factor for vascular access dysfunction in hemodialysis patients. Reducing TMAO levels may potentially decrease the incidence of vascular access dysfunction, warranting further investigation into this therapeutic approach.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of a Reentry Device for Endovascular Recanalization of Central Venous Occlusions Associated With Failing Hemodialysis Access. 再入装置在血液透析通路失败相关中心静脉闭塞血管内再通中的应用。
Yonghun Kim, Jeong Min Lee, Jee Hyun Baek, Tae Won Choi, Jinoo Kim, Je Hwan Won, Yohan Kwon
{"title":"Use of a Reentry Device for Endovascular Recanalization of Central Venous Occlusions Associated With Failing Hemodialysis Access.","authors":"Yonghun Kim, Jeong Min Lee, Jee Hyun Baek, Tae Won Choi, Jinoo Kim, Je Hwan Won, Yohan Kwon","doi":"10.1111/hdi.13262","DOIUrl":"https://doi.org/10.1111/hdi.13262","url":null,"abstract":"<p><strong>Introduction: </strong>To evaluate the technical feasibility and safety of a reentry device for endovascular recanalization of central venous occlusions associated with dysfunctional arteriovenous fistulas.</p><p><strong>Methods: </strong>Between January 2013 and December 2023, 20 patients (13 women; mean age, 61.1 years) with dysfunctional fistulas attributed to central venous occlusion underwent treatment using an Outback LTD reentry device. All patients had experienced unsuccessful recanalization attempts using conventional endovascular techniques. Symptoms included increased venous pressure during hemodialysis (N = 8), arm swelling (N = 8), absence of flow (N = 1), graft thrombosis (N = 2), and maturation failure (N = 1). The mean age of the fistulas was 56.1 months, and 11 patients had a history of angioplasty. An Outback LTD reentry device was used when conventional endovascular techniques were unsuccessful.</p><p><strong>Findings: </strong>Occlusions were observed at the junction of the subclavian and innominate veins (N = 15) and in the right innominate vein (N = 2), subclavian vein (N = 1), and axillary vein of the arm (N = 2). The reentry device was introduced via the fistula (N = 11), femoral vein (N = 8), or internal jugular vein (N = 1). Technical success was achieved in 18 patients (90.0%), all of whom successfully underwent hemodialysis. Eight patients with arm swelling experienced symptom relief. In the 14 patients available for long-term follow-up, the mean intervention-free period was 5.0 months, and the mean functional period of the fistula, with or without subsequent endovascular treatment, was 23.0 months. No complications were observed.</p><p><strong>Discussion: </strong>An Outback reentry device may be used for central venous occlusions when conventional techniques are unsuccessful.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Intradialytic Weight Gain on Left Ventricular Function and Characteristics in Hemodialysis Patients. 血液透析患者体内体重增加对左心室功能及特征的影响。
Marieta P Theodorakopoulou, Vasileios Anastasiou, Fotini Iatridi, Vasileios Kamperidis, Artemios Karagiannidis, Eleni Karkamani, Areti Georgiou, Erasmia Sampani, Konstantinos Tsilonis, Antonios Ziakas, Pantelis Sarafidis
{"title":"Impact of Intradialytic Weight Gain on Left Ventricular Function and Characteristics in Hemodialysis Patients.","authors":"Marieta P Theodorakopoulou, Vasileios Anastasiou, Fotini Iatridi, Vasileios Kamperidis, Artemios Karagiannidis, Eleni Karkamani, Areti Georgiou, Erasmia Sampani, Konstantinos Tsilonis, Antonios Ziakas, Pantelis Sarafidis","doi":"10.1111/hdi.13257","DOIUrl":"https://doi.org/10.1111/hdi.13257","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary circulation is particularly overloaded in hemodialysis patients with high interdialytic weight gain (IDWG), as evidenced by deterioration in right ventricular function indices. This study aimed to evaluate the impact of the degree of fluid accumulation on left ventricular (LV) systolic and diastolic function and sizing characteristics.</p><p><strong>Methods: </strong>This is a post hoc analysis of a cross-over study in 41 hemodialysis patients. Study participants were stratified using the recommended threshold IDWG% into a higher (> 4.5%) and a lower (< 4.5%) IDWG% group. All participants underwent 4 echocardiographic assessments at the start and the end of the 2-day and the 3-day interdialytic interval.</p><p><strong>Results: </strong>Over the 2-day interval, stroke volume and cardiac output increments were more prominent in the higher IDWG% group (> 4.5% 22.97 ± 18.45 vs. < 4.5% 0.95 ± 29.1 mmHg, p = 0.006; > 4.5% 1.32 ± 1.39 vs. < 4.5% -0.36 ± 2.08 L/m<sup>2</sup>, p = 0.004, respectively). Over the 3-day interval, significant increments in stroke volume were observed for both groups. With regard to diastolic function, a significant increase in E wave, E/A, and E/E'm lateral ratios was observed over the 3-day interval, and significant between-group differences in interdialytic changes were detected for the E/A ratio (IDWG > 4.5% 0.35 ± 0.29 vs. < 4.5% 0.06 ± 0.44, p = 0.035) and the E wave (IDWG > 4.5% 0.31 ± 0.24 vs. < 4.5% 0.10 ± 0.19, p = 0.02). Left atrial dimensions and LV mass were enlarged to a similar extent in both study groups during both intervals.</p><p><strong>Conclusions: </strong>Patients exceeding the recommended IDWG threshold experience more pronounced changes in indices of LV function and significant deterioration of preload-dependent indexes of LV diastolic function.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Our Experience With Arteriovenous Fistula in Elderly Patients With Chronic Kidney Disease. 老年慢性肾病患者动静脉瘘的治疗体会。
Güler Gülsen Ersoy, Burak Tamtekin, İsmail Taşkent
{"title":"Our Experience With Arteriovenous Fistula in Elderly Patients With Chronic Kidney Disease.","authors":"Güler Gülsen Ersoy, Burak Tamtekin, İsmail Taşkent","doi":"10.1111/hdi.13247","DOIUrl":"https://doi.org/10.1111/hdi.13247","url":null,"abstract":"<p><strong>Objectives: </strong>In recent years, advances in medical care have expanded the boundaries of aging, leading to an increasing number of elderly individuals requiring hemodialysis (HD). The use of arteriovenous (AV) fistulas for HD in elderly patients remains controversial due to concerns about life expectancy, vascular aging, and comorbidities. This study aimed to compare AVF outcomes in patients aged ≥ 70 years with those aged < 70 years to evaluate the safety and efficacy of AVFs in elderly patients.</p><p><strong>Materials and methods: </strong>This retrospective, single-center study included 202 patients who underwent AVF creation for end-stage kidney disease between 2022 and 2024. Patients were divided into two groups: ≥ 70 years (n = 76) and < 70 years (n = 126). AVF maturation, complication rates, the need for new AVF, and primary and secondary patency rates were compared. Kaplan-Meier analysis and the log-rank test were used to assess patency outcomes.</p><p><strong>Results: </strong>AVF maturation rates were comparable between the ≥ 70 years group (50.0%) and the < 70 years group (56.9%) (p = 0.330). The need for a new AVF within 6 months was 11.2% in the ≥ 70 years group and 17.6% in the < 70 years group (p = 0.387). There were no significant differences in late complications (p = 0.157), AVF location preferences (p = 0.450), or secondary intervention rates (p = 0.967). Kaplan-Meier analysis revealed no significant difference in primary (p = 0.411) or secondary (p = 0.432) patency between the two groups.</p><p><strong>Conclusion: </strong>Despite age-related concerns, AVF outcomes in elderly patients were comparable to those in younger individuals. AVFs should be considered a viable vascular access option for HD in elderly patients, provided that patient-specific factors are taken into account.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tigecycline Induced Sweet Syndrome in a Patient on Maintenance Hemodialysis. 替加环素致维持性血液透析患者甜蜜综合征1例。
Periklis Dousdampanis, Eleni Koutroulia, Pinelopi Nterma, Christos Siavelis, Elefteria Sarri, Georgia Kiriakou, Panagiotis Aroukatos, Zoi Tegou
{"title":"Tigecycline Induced Sweet Syndrome in a Patient on Maintenance Hemodialysis.","authors":"Periklis Dousdampanis, Eleni Koutroulia, Pinelopi Nterma, Christos Siavelis, Elefteria Sarri, Georgia Kiriakou, Panagiotis Aroukatos, Zoi Tegou","doi":"10.1111/hdi.13248","DOIUrl":"https://doi.org/10.1111/hdi.13248","url":null,"abstract":"<p><p>Sweet syndrome or acute febrile neutrophilic dermatosis is a very uncommon condition, especially in patients on chronic hemodialysis. Sweet syndrome is characterized by painful erythematous plaques, papules, and nodules of abrupt onset, associated with fever and malaise. We describe a 44-year-old woman on chronic hemodialysis due to diabetic nephropathy who developed Sweet syndrome after intravenous administration of tigecycline due to an enterococcus infection. There is a paucity of data regarding Sweet syndrome in hemodialysis patients; nevertheless, this syndrome merits more attention in nephrological clinical practice. We suggest that Sweet syndrome should be considered if the abrupt appearance of erythematous plaques and nodules with fever is presented in a hemodialysis patient. Nephrologists should be aware of this uncommon condition in order to timely recognize this syndrome. Interestingly, tigecycline is another drug implicated in the development of drug-induced Sweet syndrome.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variations in Serum Albumin Levels Over Time in Patients Treated With Conventional Hemodialysis or Expanded Hemodialysis: A Cohort Study. 常规血液透析或扩展血液透析患者血清白蛋白水平随时间的变化:一项队列研究。
Juan C Castillo, Jasmin Vesga, Angela Rivera, Peter Rutherford, Ricardo Sanchez, Henry Oliveros, Bengt Lindholm, Mauricio Sanabria
{"title":"Variations in Serum Albumin Levels Over Time in Patients Treated With Conventional Hemodialysis or Expanded Hemodialysis: A Cohort Study.","authors":"Juan C Castillo, Jasmin Vesga, Angela Rivera, Peter Rutherford, Ricardo Sanchez, Henry Oliveros, Bengt Lindholm, Mauricio Sanabria","doi":"10.1111/hdi.13232","DOIUrl":"https://doi.org/10.1111/hdi.13232","url":null,"abstract":"<p><strong>Introduction: </strong>Hypoalbuminemia is a well-established risk factor for mortality in chronic hemodialysis (HD) patients. To evaluate the association of time-varying serum albumin with the type of dialyzer, we analyzed serum albumin over time in two cohorts of HD patients, one receiving HDx therapy enabled by the Theranova dialyzer and the other conventional HD with high-flux dialyzer (HF-HD).</p><p><strong>Methods: </strong>In this cohort study, 1092 prevalent adult HD patients (mean age 61 years; 62% men; 42% had diabetes; 19% had cardiovascular disease) at Renal Care Services Colombia undergoing either HDx therapy enabled by Theranova dialyzer (n = 559) or HF-HD (n = 533) were enrolled between September 1, 2017, and November 30, 2017, and then underwent repeated measurements of serum albumin for up to 48 months. Sociodemographic and clinical, and laboratory characteristics at baseline were recorded, and a repeated-measures analysis of variance (ANOVA) was conducted to examine differences in means of serum albumin at different time points. To evaluate the association between dialysis membrane and albumin levels during the follow-up, a linear panel regression analysis was performed, allowing control for imbalances in the cohorts of baseline clinical and demographic variables, as well as the time-dependent variables.</p><p><strong>Results: </strong>Mean albumin concentration remained above 3.8 g/dL and did not differ over time between HDx and HF-HD (p = 0.789). No association (p = 0.208) between serum albumin levels varying over time and the use of the Theranova dialyzer was found in the linear panel regression model. However, serum albumin was linked to both inflammatory and nutritional markers, including C-reactive protein, ratio of platelets to lymphocytes, and protein-energy wasting.</p><p><strong>Conclusion: </strong>Variations in serum albumin levels over time were associated with protein-energy wasting, inflammation, high age, vascular access, and hospitalizations, but not with the type of dialyzer.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemodynamic Monitoring During Hemodialysis Using Bioimpedance: A Comparison of Changes in Resistance Between Different Body Segments. 利用生物阻抗监测血液透析过程中的血流动力学:不同身体部位间阻力变化的比较。
Melanie K Schoutteten, Patrick van der Heijden, Astrid D H Brys, Bart De Moor, Chris van Hoof, Geert Langereis, Jeroen P Kooman, Pieter M Vandervoort
{"title":"Hemodynamic Monitoring During Hemodialysis Using Bioimpedance: A Comparison of Changes in Resistance Between Different Body Segments.","authors":"Melanie K Schoutteten, Patrick van der Heijden, Astrid D H Brys, Bart De Moor, Chris van Hoof, Geert Langereis, Jeroen P Kooman, Pieter M Vandervoort","doi":"10.1111/hdi.13245","DOIUrl":"https://doi.org/10.1111/hdi.13245","url":null,"abstract":"<p><strong>Introduction: </strong>Prevention of hemodynamic complications during hemodialysis remains challenging. Although whole body bioimpedance is well established in fluid status assessment, its use for dynamic or continuous recordings is limited. A segmental approach may serve this purpose better. This study investigates which body segment is best targeted to measure bioimpedance for hemodynamic monitoring.</p><p><strong>Methods: </strong>In this observational study, serial bioimpedance measurements were conducted on the whole body, lower leg, upper arm, and thorax of 15 patients during two hemodialysis sessions. The resistance component of bioimpedance was used to investigate the relationship with changes in volume and systolic blood pressure (SBP).</p><p><strong>Findings: </strong>Predialysis to postdialysis changes in relative resistance between the two sessions revealed the lowest intraclass correlation coefficient for upper arm (0.023) and the highest for thoracic resistance (0.728). Correlation between ultrafiltration volume and relative resistance was comparable between upper arm and thoracic segment (0.538 [0.447-0.618] and 0.537 [0.446-0.617], both p < 0.001, respectively) and the highest for whole-body and lower leg (0.697 [0.63-0.754] and 0.670 [0.598-0.731], both p < 0.001, respectively). In contrast, the correlation between changes in SBP and relative resistance was the highest in the thoracic segment (-0.33 [-0.432 to -0.219], p < 0.001) and the lowest for whole body measurements (-0.154 [-0.269 to -0.036], p = 0.01). In addition, multiple regression analysis indicated thoracic resistance as the best predictor for changes in SBP (β = -0.261 [-0.353 to -0.126], p < 0.001).</p><p><strong>Discussion: </strong>These findings suggest that the thorax is the most suitable region for segmental bioimpedance measurements to assess hemodynamic parameters. Thoracic bioimpedance may innovate the hemodynamic monitoring of hemodialysis patients.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Long-Term Patency Rate and Factors Influencing Dysfunction of the Autogenous Arteriovenous Fistula in Hemodialysis Patients: A Retrospective Study. 血透患者自体动静脉瘘长期通畅率及功能障碍影响因素的回顾性研究。
Qinghua He, Yu Zhou, Chen Chen, Baojia Zheng, Jingjing Zhang, Fulan Wang
{"title":"The Long-Term Patency Rate and Factors Influencing Dysfunction of the Autogenous Arteriovenous Fistula in Hemodialysis Patients: A Retrospective Study.","authors":"Qinghua He, Yu Zhou, Chen Chen, Baojia Zheng, Jingjing Zhang, Fulan Wang","doi":"10.1111/hdi.13246","DOIUrl":"https://doi.org/10.1111/hdi.13246","url":null,"abstract":"<p><strong>Introduction: </strong>Autogenous arteriovenous fistula (AV fistula) dysfunction continues to be a widespread clinical challenge, adversely impacting both patients and society as a whole. The aim of this study was to investigate the long-term patency rate of AV fistula, explore the factors that contribute to AV fistula dysfunction, and present the findings in a way that can guide clinical practice.</p><p><strong>Methods: </strong>This retrospective cohort study enrolled patients who underwent AV fistula creation and subsequent hemodialysis at a tertiary A-level hospital in Chongqing, China. Demographic, clinical, and laboratory characteristics of the patients, as well as AV fistula dysfunction, were retrospectively reviewed from electronic health records. Cox proportional hazards regression analysis was used to analyze the factors influencing AV fistula dysfunction, and a forest plot was created to visualize the results. Additionally, Kaplan-Meier survival analysis was used to analyze AV fistula survival.</p><p><strong>Findings: </strong>This study analyzed 226 patients undergoing hemodialysis, demonstrating cumulative AV fistula patency rates of 82.1% at 12 months, 60.7% at 36 months, 45.4% at 60 months, and 33.5% at 84 months. Univariate Cox proportional hazard regression analysis identified six variables associated with AV fistula dysfunction (p < 0.1): body mass index (BMI), preemptive AV fistula creation, diabetes, total cholesterol, albumin, and uric acid. Subsequent multivariate analysis revealed four independent predictors for dysfunction: elevated BMI (HR: 1.58, p = 0.016), preemptive AV fistula creation (HR: 0.67, p = 0.029), albumin (HR: 2.83, p < 0.001), and uric acid (HR: 1.57, p = 0.020).</p><p><strong>Discussion: </strong>Our study findings indicated that overweight, hypoalbuminemia, and high concentrations of uric acid were independent risk factors for AV fistula dysfunction. In contrast, preemptive AV fistula creation was an independent protective factor against AV fistula dysfunction. Therefore, early interventions and surveillance for these factors should be performed to improve long-term AV fistula patency rates.</p>","PeriodicalId":94027,"journal":{"name":"Hemodialysis international. International Symposium on Home Hemodialysis","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Massive Hemothorax Induced by Tunneled Dialysis Catheter Placement via the Left Internal Jugular Vein: A Case Report. 经左颈内静脉放置隧道式透析导管致迟发性大量血胸1例。
Ping Shi, Mengyue Zhu, Yi Zhang, Jun Xu, Hongbin Mou
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