{"title":"Bridging InsigHts from the MEdical Information Department with Alirocumab Pen Use for a Better PAtient JouRney and HCP-Community Engagement (HEAR Project).","authors":"Michela Barisone, Emanuela Folco, Federica Bonaiti, Paola Ferrario, Myriam Luciano, Eleonora Consolo, Federica Ribacchi, Lucia Notarianni, Andrea Rizzi, Leonardo De Luca","doi":"10.1093/eurjcn/zvag109","DOIUrl":"https://doi.org/10.1093/eurjcn/zvag109","url":null,"abstract":"<p><strong>Aims: </strong>The HEAR Project was initiated because of unsolicited requests from patients, caregivers, and healthcare professionals (HCPs) regarding the correct use of the alirocumab pen. This is the first example from Italy wherein patients' perspectives were considered to gain a deeper understanding of how to implement care pathways for the management of hypercholesterolaemia.</p><p><strong>Methods and results: </strong>Unsolicited spontaneous questions regarding alirocumab received by the Sanofi S.r.l. Medical Information Department or Device Call Centre from patients, caregivers, or HCPs from Italy between June 2019 and October 2022 were analysed. The analysis focused on insights regarding the handling/storage of alirocumab pen. In 2021, from 30,000 proprotein convertase subtilisin/kexin type 9 (PCSK9)-inhibitor users in Italy (30,176 patients: 16,921 evolocumab users and 13,255 alirocumab users), 1,165 unsolicited spontaneous questions regarding alirocumab were collected, including 297 questions (approximately 2% of total PCSK9-inhibitor alirocumab administrations) related to pen use (263 [22.6%]) or product storage (34 [2.9%]).</p><p><strong>Conclusions: </strong>Findings from the HEAR Project support exploring the perspectives of patients who have specific questions about using the device to administer alirocumab for the treatment of hypercholesterolaemia. The findings provide crucial insights for improving care pathways for patients with very-high cardiovascular risk and hypercholesterolaemia. Further analyses are warranted to generate insights with a larger sample size and a wider geographic patient population.</p>","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Statin denialism and digital echo chambers: navigating the landscape of online cardiovascular health information.","authors":"Reindolf Anokye","doi":"10.1093/eurjcn/zvag061","DOIUrl":"https://doi.org/10.1093/eurjcn/zvag061","url":null,"abstract":"","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shrikant Ramkrishna Sahu, Lakshman Iyer, Guruprasad Rai, Ramachandran Padmakumar, Abraham Samuel Babu
{"title":"Effectiveness of exercise-based prehabilitation on pre and postoperative outcomes of patients undergoing cardiac surgery - an umbrella review of systematic reviews.","authors":"Shrikant Ramkrishna Sahu, Lakshman Iyer, Guruprasad Rai, Ramachandran Padmakumar, Abraham Samuel Babu","doi":"10.1093/eurjcn/zvag117","DOIUrl":"https://doi.org/10.1093/eurjcn/zvag117","url":null,"abstract":"<p><strong>Aims: </strong>Individuals undergoing cardiac surgery are becoming older, frailer, and less mobile. Prehabilitation has shown to improve postoperative outcomes by optimizing preoperative physical function. This umbrella review aims to pool the systematic reviews assessing the effectiveness of exercise-based prehabilitation in cardiac surgery.</p><p><strong>Methods and results: </strong>The review followed the PRIOR checklist. PubMed, Embase, CINAHL, Cochrane library, Scopus, Web of science, ProQuest NAHD, ProQuest HMC, Open Grey and MedNar were searched using relevant keywords from inception to 16th December, 2024. Two reviewers screened and extracted data from the included reviews and assessed primary study overlap with the corrected covered area. Methodological quality of the reviews was evaluated with the A MeaSurement Tool to Assess systematic Reviews - 2 scale. Certainty of evidence was assessed using a previously developed criteria for overview of reviews. Six systematic reviews with 30 unique trials and 6705 participants were included. The interventions assessed included breathing exercises, inspiratory muscle training, and exercise training. Prehabilitation reduced length of hospital stay, postoperative pulmonary complications, and clinically improved functional capacity with a very low to moderate certainty of evidence. However, there was uncertainty regarding the effects pertaining to adverse events and quality of life. The methodological quality of all reviews was critically low. The primary trials scored poorly in the domains of selection and detection bias.</p><p><strong>Conclusions: </strong>Exercise-based prehabilitation might reduce length of hospital stay and postoperative complications, and improve functional capacity. However, the quality of evidence is poor, and individual discretion is required before implementing them into practice.</p>","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147847835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muzeyyen Seckin, Mark C Petrie, Simon Stewart, Bridget Johnston
{"title":"Full spectrum of symptoms associated with heart failure: a mixed method systematic review and narrative synthesis.","authors":"Muzeyyen Seckin, Mark C Petrie, Simon Stewart, Bridget Johnston","doi":"10.1093/eurjcn/zvaf148","DOIUrl":"10.1093/eurjcn/zvaf148","url":null,"abstract":"<p><strong>Aims: </strong>To investigate European Society of Cardiology (ESC) guideline-defined 'typical' and 'less typical' heart failure (HF) symptoms, as well as non-ESC symptoms, and to explore how ESC-defined symptoms vary by care setting, age, and sex.</p><p><strong>Methods and results: </strong>Mixed-method systematic review and narrative synthesis through six electronic databases. Quality was assessed using Joanna Briggs Institute critical appraisal checklists. Symptoms were grouped into ESC (typical/less typical) and non-ESC symptoms. Differences in ESC typical and less typical symptoms were investigated in hospital vs. community, <65 vs. ≥65 years old age, and men vs. women. Fifty-eight papers (43 quantitative, 11 qualitative, and 4 mixed-method) were included. Fifty-six out of fifty-eight studies observed at least one of the ESC typical and/or less typical symptoms. Some of the 'less typical symptoms' were rarely reported (e.g. wheezing in three and bendopnea in one). Thirty-eight non-ESC symptoms were observed in 58 studies. Some non-ESC symptoms were commonly observed [e.g. chest pain/discomfort (37/58), difficulty sleeping (32/58), and nausea/vomiting/indigestion (30/58)]. Cough, palpitations, and dizziness were observed more in community than hospital whereas wheezing was observed more in hospital. Typical symptoms (orthopnoea/paroxysmal nocturnal dyspnoea/swelling) were more often observed in cohorts ≥65 (than <65) years of age. Due to the paucity of women in studies, there was little information available to compare symptoms of men and women.</p><p><strong>Conclusion: </strong>There is a more diverse range of symptoms among HF population than has previously been described. There is need for comprehensive, person-centred symptom assessment protocol and more inclusive clinical guidelines, highlighting symptom variability in HF population across different demographic and clinical variations.</p><p><strong>Registration: </strong>PROSPERO CRD42020185786.</p>","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":"239-255"},"PeriodicalIF":3.9,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144736344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Positioning the front-door-score tool for NSTEMI in emergency departments.","authors":"Evangeline Loh, Kuan Win Sen, Wilson Tam","doi":"10.1093/eurjcn/zvaf250","DOIUrl":"10.1093/eurjcn/zvaf250","url":null,"abstract":"","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":"386-387"},"PeriodicalIF":3.9,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heterogeneous trajectories of health-related quality of life and their association with prognosis in patients with coronary heart disease and chronic heart failure.","authors":"Wei Guo, Jing Tian, Jingjing Yan, Jing Li, Yanbo Zhang, Qinghua Han","doi":"10.1093/eurjcn/zvaf134","DOIUrl":"10.1093/eurjcn/zvaf134","url":null,"abstract":"<p><strong>Aims: </strong>Currently, there is limited knowledge regarding the long-term health-related quality-of-life (HRQoL) trajectories of patients with coronary heart disease (CHD) and chronic heart failure (CHF) after discharge. In this study, we identified the HRQoL trajectories of these people through group-based trajectory modelling (GBTM) and explored their prognosis.</p><p><strong>Methods and results: </strong>A total of 658 patients with CHD and CHF were recruited in this multi-centre, prospective cohort study from June 2017. Health-related quality of life was assessed using the Kansas City Cardiomyopathy Questionnaire-12 at seven time points: at admission and at 1, 3, 6, 12, 18, and 24 months after discharge. Group-based trajectory modelling identified four distinct patterns of HRQoL trajectories: quick deterioration (7.14%), slow deterioration (14.74%), quick improvement (34.19%), and stable improvement (43.92%). Age >65 years, male, higher N-terminal pro-B-type natriuretic peptide levels, poor baseline health status, lower diastolic blood pressure and albumin levels, as well as comorbid chronic kidney disease, hypertension, and stroke were associated with HRQoL deteriorating trajectory (P < 0.05). After adjusting for confounders, Cox proportional hazards models indicated that compared with the high HRQoL-stable improvement group, the low HRQoL-quick deterioration group, moderate HRQoL-slow deterioration group, and moderate HRQoL-quick improvement group had increased risks of all-cause mortality in the following years.</p><p><strong>Conclusion: </strong>The HRQoL trajectories within 2 years after discharge in patients with CHD and CHF exhibit significant heterogeneity and are closely linked to subsequent risk of mortality. This finding enhances the understanding of disease progression and provides scientific evidence to inform personalized nursing interventions and treatment strategies in clinical practice.</p><p><strong>Registration: </strong>Chinese Clinical Trial Registry: ChiCTR2100043337.</p>","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":"288-299"},"PeriodicalIF":3.9,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145890651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth Curtis, Peta Drury, Wendy Garstang-Harker, Astin Lee, Lorraine Fields
{"title":"Reducing waste in the cardiac catheterization laboratory: insights from a co-design workshop.","authors":"Elizabeth Curtis, Peta Drury, Wendy Garstang-Harker, Astin Lee, Lorraine Fields","doi":"10.1093/eurjcn/zvaf202","DOIUrl":"10.1093/eurjcn/zvaf202","url":null,"abstract":"<p><strong>Aims: </strong>Healthcare is a significant contributor to environmental degradation, with cardiac catheterization laboratories (cath labs) recognized as high-resource clinical environments. The aim of this study was to identify modifiable drivers of clinical waste and co-develop practical, locally relevant strategies to improve environmental sustainability within a cath lab setting.</p><p><strong>Methods and results: </strong>A qualitative co-design workshop was conducted at a metropolitan tertiary hospital in Australia. Ten participants, including clinical staff, hospital administrators, support services personnel, and community members, engaged in structured discussions using a World Café model. Data were collected through field notes, participant-generated materials, and member checking, and were analysed thematically using an inductive approach. Six interrelated themes emerged: (i) excessive packaging and procurement practices, (ii) underutilization and disposability of clinical stock, (iii) behavioural norms and change readiness, (iv) infrastructure and feasibility constraints, (v) community and patient engagement, and (vi) measurement, leadership, and accountability. Participants expressed motivation to reduce waste but identified systemic and organizational barriers that limited the adoption of sustainable practices.</p><p><strong>Conclusion: </strong>Sustainability in the cath lab is shaped by modifiable factors beyond individual clinician behaviour, including procurement policies, stock management, and leadership structures. Embedding sustainability within organizational processes and engaging patients and communities are essential to achieving meaningful, lasting reductions in healthcare waste.</p>","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":"402-409"},"PeriodicalIF":3.9,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Harnessing mobile health to support recovery after cardiac surgery.","authors":"Maria Hayes, Suzanne Fredericks","doi":"10.1093/eurjcn/zvaf236","DOIUrl":"10.1093/eurjcn/zvaf236","url":null,"abstract":"","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":"364-365"},"PeriodicalIF":3.9,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Izabella Uchmanowicz, Arkadiusz Matras, Michał Czapla
{"title":"From muscle mass to muscle function: redefining recovery after cardiovascular surgery.","authors":"Izabella Uchmanowicz, Arkadiusz Matras, Michał Czapla","doi":"10.1093/eurjcn/zvaf214","DOIUrl":"10.1093/eurjcn/zvaf214","url":null,"abstract":"","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":"327-328"},"PeriodicalIF":3.9,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a self-assessment tool for transition to daily life post-cardiac surgery.","authors":"Akiko Makino, Satoshi Nakata, Toshiko Yoshida","doi":"10.1093/eurjcn/zvaf201","DOIUrl":"10.1093/eurjcn/zvaf201","url":null,"abstract":"<p><strong>Aims: </strong>Physical, psychological, and social distress experienced by patients undergoing cardiac surgery has long-term effects on quality of life. Therefore, patient-centred, continuous, and comprehensive transitional care is required. We aimed to develop a Self-Assessment Tool for Transition to Daily Life (SAT-TDL) and to examine its reliability and validity.</p><p><strong>Methods and results: </strong>A draft SAT-TDL was developed and validated by experts. A modified version was then developed through patient interviews and acceptability assessment, and its reliability and validity were evaluated through exploratory and confirmatory factor analyses. Construct validity was tested using the standard version of the 12-item Short Form Health Survey (SF-12v2). The initial 56-item SAT-TDL draft was modified into a 28-item pilot version and then into a 27-item version based on feedback from seven patients who had undergone cardiac surgery. From 340 valid responses, the 27-item SAT-TDL yielded four domains through item and factor (exploratory and confirmatory) analyses. Cronbach's alpha coefficient for the entire tool was 0.95. Hypothesis testing revealed significant correlations between the psychological aspects of the SF-12v2 and 'psychological transitions' domain of the SAT-TDL, and between the social aspects of the SF-12v2 and 'continuation of self-management' and 'meeting care needs' domains of the SAT-TDL. The final model fit was generally good (CMIN/DF = 3.3285, GFI = 0.809, AGFI = 0.771, CFI = 0.883, and RMSEA = 0.083).</p><p><strong>Conclusion: </strong>The SAT-TDL is a reliable and valid self-assessment tool. Sharing information on patients' post-discharge transitions and care needs with medical staff may support smoother recovery and improve the quality of life after cardiac surgery.</p>","PeriodicalId":93997,"journal":{"name":"European journal of cardiovascular nursing","volume":" ","pages":"388-397"},"PeriodicalIF":3.9,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145919468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}