Diabetes & vascular disease research最新文献_第3页

Progression of insulin resistance in individuals with type 1 diabetes: A retrospective longitudinal study on individuals from Thailand. 1 型糖尿病患者胰岛素抵抗的进展：对泰国患者的回顾性纵向研究。

Diabetes & vascular disease research Pub Date : 2023-11-01 DOI: 10.1177/14791641231221202

Thanes Jirawatwarakul, Thakorn Pruktanakul, Chaitong Churuangsuk, Warut Aunjitsakul, Wantanee D Tsutsumi, Rattana Leelawattana, Supamai Soonthornpun, Ramzi A Ajjan, Noppadol Kietsiriroje

{"title":"Progression of insulin resistance in individuals with type 1 diabetes: A retrospective longitudinal study on individuals from Thailand.","authors":"Thanes Jirawatwarakul, Thakorn Pruktanakul, Chaitong Churuangsuk, Warut Aunjitsakul, Wantanee D Tsutsumi, Rattana Leelawattana, Supamai Soonthornpun, Ramzi A Ajjan, Noppadol Kietsiriroje","doi":"10.1177/14791641231221202","DOIUrl":"https://doi.org/10.1177/14791641231221202","url":null,"abstract":"Aims: To investigate temporal changes in glycaemic control and weight contributing to insulin resistance (IR), in Thai individuals with type 1 diabetes (T1D).Methods: Longitudinal data of 69 individuals with T1D were retrospectively collected over a median follow-up of 7.2 years. The estimated glucose disposal rate (eGDR), a marker of IR, was calculated using an established formula. Individuals were assigned as insulin-sensitive T1D (the latest eGDR≥8 mg/kg/min), or insulin-resistant T1D/double diabetes (the latest eGDR<8 mg/kg/min). Generalised linear mixed model was employed to compare the temporal patterns of HbA1c, BMI, and eGDR between the two groups.Results: 26 insulin-resistant T1D had a gradual decline in eGDR, corresponding with increased weight and HbA1c. In contrast, 43 insulin-sensitive T1D had stable insulin sensitivity with an improvement in HbA1c over time, associated with a modest weight gain. Fluctuations of glucose levels were observed during the early diabetes course leading to unstable eGDR, thus limiting the use of eGDR to classify insulin-resistant T1D.Conclusion: T1D individuals who eventually develop IR are likely to experience early increasing IR over time. In contrast, those who ultimately do not have IR, maintain their insulin sensitivity throughout their course at least in the medium term.","PeriodicalId":93978,"journal":{"name":"Diabetes & vascular disease research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10722936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138807977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipoprotein (a) as a predictor of diabetic retinopathy in patients with type 2 diabetes: A systematic review. 脂蛋白(a)作为2型糖尿病患者糖尿病视网膜病变的预测因子:一项系统综述。

Diabetes & vascular disease research Pub Date : 2023-11-01 DOI: 10.1177/14791641231197114

Mohammad Sadra Gholami Chahkand, Fatemeh Esmaeilpour Moallem, Abolfazl Qezelgachi, Kiana Seifouri, Armin Pesaran Afsharian, Farzad Sheikhzadeh, Atefe Poursalehi, Fateme Sadat Fani Sadrabadi, Mehrnush Saghab Torbati, Mohaddese Ramezanzade, Goharsharieh Alishiri, Arina Ansari, Emad Zare Dehabadi, Saeed Karimi Matloub, Zahra Sheikh, Niloofar Deravi, Saba Mehrtabar, Fatemeh Chichagi, Neda Faal Hamedanchi, Mohammadreza Arzaghi, Mahla Asadi, Parisa Alsadat Dadkhah, Akram Ansari

{"title":"Lipoprotein (a) as a predictor of diabetic retinopathy in patients with type 2 diabetes: A systematic review.","authors":"Mohammad Sadra Gholami Chahkand, Fatemeh Esmaeilpour Moallem, Abolfazl Qezelgachi, Kiana Seifouri, Armin Pesaran Afsharian, Farzad Sheikhzadeh, Atefe Poursalehi, Fateme Sadat Fani Sadrabadi, Mehrnush Saghab Torbati, Mohaddese Ramezanzade, Goharsharieh Alishiri, Arina Ansari, Emad Zare Dehabadi, Saeed Karimi Matloub, Zahra Sheikh, Niloofar Deravi, Saba Mehrtabar, Fatemeh Chichagi, Neda Faal Hamedanchi, Mohammadreza Arzaghi, Mahla Asadi, Parisa Alsadat Dadkhah, Akram Ansari","doi":"10.1177/14791641231197114","DOIUrl":"10.1177/14791641231197114","url":null,"abstract":"Background: Lipoprotein a (LP(a)), an LDL-like lipoprotein, known as a risk factor for cardiovascular diseases, has a controversial association with diabetic retinopathy in patients with type 2 diabetes-the current systematic review aimed to critically assess the association between LP(a) and diabetic retinopathy.Methods: A systematic review of relevant studies was conducted after a thorough search in PubMed, Scopus, and Google Scholar electronic databases. We used English observational, case-control, and prospective cohort studies published up to August 2022, including type 2 diabetic patients as the population, diabetic retinopathy as the outcome, and LP(a) as the intervention.Result: 17 relevant studies, including 4688 patients with diabetes, were included in this systematic review. While in 13 studies, Lipoprotein(a) was recognized as a risk factor for diabetic retinopathy, only three studies reported no evidence of a relationship between the two. Also, another study showed a mixed outcome of the relationship between LP(a) and diabetic retinopathy.Conclusion: High serum lipoprotein(a) in patients with type 2 diabetes is considered a risk factor for diabetic retinopathy. However, further large-scaled cohort studies are still required to validate this finding.","PeriodicalId":93978,"journal":{"name":"Diabetes & vascular disease research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10685788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138453348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive power of isolated high home systolic blood pressure for cardiovascular outcomes in individuals with type 2 diabetes mellitus: KAMOGAWA-HBP study. 孤立的家庭高收缩压对 2 型糖尿病患者心血管后果的预测力：KAMOGAWA-HBP 研究。

Diabetes & vascular disease research Pub Date : 2023-11-01 DOI: 10.1177/14791641231221264

Yukako Hosomi, Emi Ushigome, Nobuko Kitagawa, Noriyuki Kitagawa, Toru Tanaka, Goji Hasegawa, Masayoshi Ohnishi, Sei Tsunoda, Hidetaka Ushigome, Naoto Nakamura, Mai Asano, Masahide Hamaguchi, Masahiro Yamazaki, Michiaki Fukui

{"title":"Predictive power of isolated high home systolic blood pressure for cardiovascular outcomes in individuals with type 2 diabetes mellitus: KAMOGAWA-HBP study.","authors":"Yukako Hosomi, Emi Ushigome, Nobuko Kitagawa, Noriyuki Kitagawa, Toru Tanaka, Goji Hasegawa, Masayoshi Ohnishi, Sei Tsunoda, Hidetaka Ushigome, Naoto Nakamura, Mai Asano, Masahide Hamaguchi, Masahiro Yamazaki, Michiaki Fukui","doi":"10.1177/14791641231221264","DOIUrl":"https://doi.org/10.1177/14791641231221264","url":null,"abstract":"Aims/introduction: Isolated high home systolic blood pressure (IHHSBP) is a risk for cardiovascular disease (CVD). However, no study has shown an association between IHHSBP and CVD in diabetes. We examined the association between IHHSBP and CVD in type 2 diabetes.Materials and methods: This retrospective cohort study included 1082 individuals with type 2 diabetes, aged 20 to 90 years, without a history of macrovascular complications. Home blood pressure (HBP) was measured three times every morning and evening for 14 days. Cox proportional hazards models were used to examine the relationship between IHHSBP and CVD incidence.Results: With the normal HBP group as the reference, the adjusted hazard ratio (HR) (95% confidence interval [CI]) for CVD was 1.58 (1.02-2.43) in the IHHSBP group. Correcting for antihypertensive medication use did not change HR. Based on sex, the adjusted HR (95% CI) for CVD was 1.25 (0.74-2.13) in males and 2.28 (1.01-5.15) in females.Conclusions: In individuals with type 2 diabetes, those with IHHSBP had a higher HR for cardiovascular disease than those with normal HBP. But, Isolated high home diastolic blood pressure and high HBP were not. The association between IHHSBP and CVD was stronger in females than in males.","PeriodicalId":93978,"journal":{"name":"Diabetes & vascular disease research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10710111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138807847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of diabetes with coronary artery calcium in South Asian adults and other race/ethnic groups: The multi-ethnic study of atherosclerosis and the mediators of atherosclerosis in South Asians living in America study. 南亚成年人和其他种族/民族的糖尿病与冠状动脉钙的关系：居住在美国的南亚人动脉粥样硬化和动脉粥样硬化介质的多民族研究。

Diabetes & vascular disease research Pub Date : 2023-09-01 DOI: 10.1177/14791641231204368

Ned Premyodhin, Wenjun Fan, Millie Arora, Matthew J Budoff, Alka M Kanaya, Namratha Kandula, Latha Palaniappan, Jamal S Rana, Masood Younus, Nathan D Wong

{"title":"Association of diabetes with coronary artery calcium in South Asian adults and other race/ethnic groups: The multi-ethnic study of atherosclerosis and the mediators of atherosclerosis in South Asians living in America study.","authors":"Ned Premyodhin, Wenjun Fan, Millie Arora, Matthew J Budoff, Alka M Kanaya, Namratha Kandula, Latha Palaniappan, Jamal S Rana, Masood Younus, Nathan D Wong","doi":"10.1177/14791641231204368","DOIUrl":"10.1177/14791641231204368","url":null,"abstract":"Purpose: South Asian (SA) persons have increased risks for diabetes mellitus (DM) and atherosclerotic cardiovascular disease (ASCVD). We examined whether the association of DM with subclinical atherosclerosis assessed by coronary artery calcium (CAC) differs in SA versus other ethnic groups.Methods: We studied adults from the Multi-Ethnic Study of Atherosclerosis and the Mediators of Atherosclerosis in South Asians Living in America studies without ASCVD. CAC was examined among those normoglycemic, pre-DM and DM. Logistic regression examined pre-DM and DM with the odds of any CAC > 0 and CAC ≥ 100.Results: Among 7562 participants, CAC > 0 and CAC ≥ 100 in those with DM was highest in non-Hispanic White (NHW) (80% and 48%) and SA (72% and 41%) persons. Adjusted Ln (CAC + 1) was highest in NHW (3.68 ± 0.21) and SA (3.60 ± 0.23) (p < .01) DM patients. SA and NHW adults with DM (vs normoglycemic) had highest odds of CAC > 0 (2.13 and 2.27, respectively, p < .01). For CAC ≥ 100, SA and Chinese adults had the highest odds (2.28 and 2.27, respectively, p < .01). Fasting glucose and glycated hemoglobin were most strongly associated with CAC among SA.Conclusions: Diabetes mellitus most strongly relates to any CAC in SA and NHW adults and CAC ≥ 100 in SA and Chinese adults, helping to explain the relation of DM with ASCVD in these populations.","PeriodicalId":93978,"journal":{"name":"Diabetes & vascular disease research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41166102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracellular vesicles in gestational diabetes mellitus: A scoping review. 妊娠期糖尿病的细胞外小泡：范围界定综述。

Diabetes & vascular disease research Pub Date : 2022-03-01 DOI: 10.1177/14791641221093901

Tanvi Bathla, Akram Abolbaghaei, Agafe Bless Reyes, Dylan Burger

引用次数: 6