.•'l tJ7SCE, B. Choi, Marjolein Dohmen-Janssen, T. Hiraishi, F. Imamura, Nobuhisa Kobayashi, Haruyuki Kojima, Shoichiro Kojima, Toshimitsu Komatsu, Jeffrey A. Melby, Kazuo Murakami, T. Ohyama, A. Okayasu, T. Shibayama, T. Shigematsu, S. Suh, Tomoyuki Takahashi, K. Takikawa, Hitoshi Tanaka
{"title":"Reviewers","authors":".•'l tJ7SCE, B. Choi, Marjolein Dohmen-Janssen, T. Hiraishi, F. Imamura, Nobuhisa Kobayashi, Haruyuki Kojima, Shoichiro Kojima, Toshimitsu Komatsu, Jeffrey A. Melby, Kazuo Murakami, T. Ohyama, A. Okayasu, T. Shibayama, T. Shigematsu, S. Suh, Tomoyuki Takahashi, K. Takikawa, Hitoshi Tanaka","doi":"10.1142/S0578563405001185","DOIUrl":"https://doi.org/10.1142/S0578563405001185","url":null,"abstract":"Aoyama, Hiroaki Collins, R. Thomas Ema, Makoto Funabashi, Hitoshi Goto, Aya Gotoh, Hideo Hatta, Toshihisa Hirahara, Fumiki Horie, Masao Iba, Kosuke Ichihashi, Kou Ikeda, Toshiro Imoto, Issei Inoue, Ken Iseki, Sachiko Itoh, Hiroaki Jindal, Gaurav Jung, Han-Sung Kagohashi, Yukiko Kawabata, Hidehiko Kikuchi, Akihiko Kitajima, Hiroyuki Kobayashi, Kazuto Kosho, Tomiki Koyano, Shin Kurosawa, Kenji Lederer, Damien Lee, Nam-Seob Li, Sheng-li Marzban, Hassan Masuno, Mitsuo Mattina, Teresa Miyake, Hidehiko Mizuno, Seiji Moriyama, K Nakajima, Yuji Nakanishi, Tsuyoshi Nishijyo, Muneko Oakley, Godfrey Ochiai, Daigo Ogawa, Tetsuo Ohashi, Hirofumi Ohshima, Hayato Okamoto, Nobuhiko Okano, Junko Ooshima, Yojiro Otani, Hiroki Reichenberger, EJ Sago, Haruhiko Saitsu, Hirotomo Sato, Akira Scoazec, Jean-Yves Shibasaki, Koji Sumida, Hiroshi Suzuki, Katsushi Taguchi, Tomoaki Takahashi, Michio Takakuwa, Tetsuya Terashima, Toshio Tutgun Onrat, Serap Udagawa, Jun Volpe, Paolo Vujanic, Gordan Yamada, Gen Yamada, Shigehito Yamaguchi-Sekino, Sachiko Yamamoto, Toshiyuki Yamamoto, Yoshio Yamanaka, Michiko Yamataka, Atsuyuki Yamazaki, Hiroshi Yoshiki, Atsushi Yuri, Kazuya Zenteno, Juan Carlos bs_bs_banner","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2005-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85590242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Program","authors":"E. Hopfinger, R. Verzicco, S. Zaleski","doi":"10.1111/j.1741-4520.2004.00044.x","DOIUrl":"https://doi.org/10.1111/j.1741-4520.2004.00044.x","url":null,"abstract":"","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"46 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77483244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Congenital anomaliesPub Date : 2002-06-01DOI: 10.1111/j.1741-4520.2002.tb00858.x
T. Iguchi, Hajime Watanabe, Y. Katsu, Takeshi Mizutani, S. Miyagawa, A. Suzuki, S. Kohno, K. Sone, Hideo Kato
{"title":"Developmental toxicity of estrogenic chemicals on rodents and other species","authors":"T. Iguchi, Hajime Watanabe, Y. Katsu, Takeshi Mizutani, S. Miyagawa, A. Suzuki, S. Kohno, K. Sone, Hideo Kato","doi":"10.1111/j.1741-4520.2002.tb00858.x","DOIUrl":"https://doi.org/10.1111/j.1741-4520.2002.tb00858.x","url":null,"abstract":"ABSTRACT Antenatal sex‐hormone exposure induces lesions in mouse reproductive organs, which are similar to those in humans exposed in utero to a synthetic estrogen, diethylstilbestrol. The developing organisms including rodents, fish and amphibians are particularly sensitive to exposure to estrogenic chemicals during a critical window. Exposure to estrogens during the critical period induces long‐term changes in reproductive as well as non‐reproductive organs, including persistent molecular alterations. The antenatal mouse model can be utilized as an indicator of possible long‐term consequences of exposure to exogenous estrogenic compounds including possible environmental endocrine disrupters. Many chemicals released into the environment potentially disrupt the endocrine system in wildlife and humans, some of which exhibit estrogenic activity by binding to the estrogen receptors. Estrogen responsive genes, therefore, need to be identified to understand the molecular basis of estrogenic actions. In order to understand molecular mechanisms of estrogenic chemicals on developing organisms, we are identifying estrogen responsive genes using cDNA microarray, quantitative RT‐PCR, and differential display methods, and genes related to the estrogen‐independent vaginal changes in mice induced by estrogens during the critical window. In this review, discussion of our own findings related to endocrine distuptor issue will be provided.","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"239 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76900847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Congenital anomaliesPub Date : 2002-06-01DOI: 10.1111/j.1741-4520.2002.tb00865.x
{"title":"THE JAPANESE TERATOLOGY SOCIETY (FOREIGN MEMBERS)","authors":"","doi":"10.1111/j.1741-4520.2002.tb00865.x","DOIUrl":"https://doi.org/10.1111/j.1741-4520.2002.tb00865.x","url":null,"abstract":"","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73880289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Congenital anomaliesPub Date : 2002-06-01DOI: 10.1111/j.1741-4520.2002.tb00862.x
M. Matsuda
{"title":"The initial development of motor neurons in the neural tube of rat embryos","authors":"M. Matsuda","doi":"10.1111/j.1741-4520.2002.tb00862.x","DOIUrl":"https://doi.org/10.1111/j.1741-4520.2002.tb00862.x","url":null,"abstract":"ABSTRACT The time of origin of motor neurons and their distribution in the spinal cord was studied in rat embryos by combining whole‐embryo culture and the Islet‐1 inununostaining technique. Cells immunostained for Islet‐1 appeared in the trunk neural tube by 27 hours (corresponding to E10.625) in culture of E9.5 embryos, at which time the cell number of the neural tube in a transverse section was about 200. When the neural tube retarded developmentally by lithium treatment, the time of appearance of the motor neurons was delayed to 33 hours in culture (corresponding to E10.875), but the cell number of the neural tube was about 200. After the initial appearance of motor neurons in the ventral aspect of the neural tube, they distributed in a group in the periphery of the basal plate by 48 hours (corresponding to E11.5) in culture, although in the retarded neural tube the number of motor neurons was small and they did not form a cluster. The percentage of Islet‐1‐positive cells at the point of the same cell number of the trunk neural tube in the transverse section was higher in the retarded embryos than in controls. These results suggest that motor neurons begin to appear when the cell number of the neural tube in the transverse section becomes about 200 and their initial development is more stable than overall neural tube development.","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84369434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Congenital anomaliesPub Date : 2002-06-01DOI: 10.1111/j.1741-4520.2002.tb00860.x
X. Zhao, Y. Ozaki, N. Suzumori, Tsuyoshi Sato, K. Suzumori
{"title":"Enrichment of fetal cells from maternal blood by magnetic activated cell sorting (MACS) with fetal cell specific antibodies: One‐step versus two‐step MACS","authors":"X. Zhao, Y. Ozaki, N. Suzumori, Tsuyoshi Sato, K. Suzumori","doi":"10.1111/j.1741-4520.2002.tb00860.x","DOIUrl":"https://doi.org/10.1111/j.1741-4520.2002.tb00860.x","url":null,"abstract":"ABSTRACT We report here the results of fetal cell enrichment from maternal blood in 58 pregnant women by the use of magnetic activated cell sorting (MACS) with erythroblast‐specific and/or maternal cell specific antibodies. Two approaches were compared; one‐step MACS to enrich CD71+ (a membrane‐bound marker) or GPA+ (another marker, glycophorin A) fetal cells versus two‐step MACS to deplete CD14+ maternal cells and subsequently to enrich fetal (CD71+ or GPA+) cells. The existence of fetal cells was ensured by both FISH with Y‐specific probes and karyotyping of respective anuniotic and/or chorionic vullus cells, the results being applied for comparison of detection rate for XY fetuses between the two MACS procedures.","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"64 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2002-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73251300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}