Congenital anomalies最新文献_第10页

Analysis of Palatogenesis in the Mouse with Exencephaly Induced by Cadmium Chloride 氯化镉致畸形小鼠胚胎发育分析

Congenital anomalies Pub Date : 1994-03-01 DOI: 10.1111/j.1741-4520.1994.tb00271.x

Toshio J. Sato

{"title":"Analysis of Palatogenesis in the Mouse with Exencephaly Induced by Cadmium Chloride","authors":"Toshio J. Sato","doi":"10.1111/j.1741-4520.1994.tb00271.x","DOIUrl":"https://doi.org/10.1111/j.1741-4520.1994.tb00271.x","url":null,"abstract":"ABSTRACT It has been revealed that exencephalic mouse embryos were resistant to cleft palate induction when they were exposed to several teratogens known as cleft palate inducing agents. In the present study, palatogenesis in exencephalic mouse embryos, which were not exposed to cleft palate inducing teratogens, was observed. A single dose of 6 mg CdCl2/kg body weight was intraperitoneally injected into pregnant Jcl:ICR mice at day 7.5 of gestation (plug day = day 0). Embryos were dissected from uterus at day 13.5 to 15.5, and the secondary palate was observed with a dissecting microscope or a scanning electron microscope (SEM). Of live embryos, 71.5% had exencephaly. Palatal shelves of exencephalic embryos were elevated earlier than non‐exencephalic embryos, and there seem to be two modes of palatal fusion in exencephalic embryos. (1) “Parallel‐shape.” The anterior part of shelves were elevated at day 13.5. Distance between the opposite medial edges of both shelves decreased at the posterior part, and this closing proceeded to the anterior part, where the shelves began to fuse. (2) “V‐shape.” The posterior part of palatal shelves became closer at day 14.0 or day 14.25. The medial edge of both shelves began to fuse at this part, and this fusion proceeded anteriorly. The anterior parts of the shelves were elevated, and the medial edge of the anterior shelves was fused independently. It is suggested that these alterations of palatogenesis in exencephalic embryos are related to inhibitive mechanism(s) against cleft palate induction. Key words: palate, neural tube defects, skull, mice, cadmium","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1994-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78794378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Lethal Multiple Pterygium Syndrome with Complete Intestinal Duplication 致死性多发性翼状胬肉综合征伴完全肠道复制

Congenital anomalies Pub Date : 1994-03-01 DOI: 10.1111/j.1741-4520.1994.tb00268.x

Eun Kyung Kim, J. Chi

引用次数: 1

Clinical Features and Operative Findings of Congenital Flexion Deformity of Multiple Digits 先天性多指屈曲畸形的临床特点及手术表现

Congenital anomalies Pub Date : 1993-12-01 DOI: 10.1111/j.1741-4520.1993.tb00539.x

T. Ogino, S. Ishii, H. Kato

引用次数: 1

A Thoracic Expansion Technique as a Life‐Saving Procedure for Jeune Syndrome (Asphyxiating Thoracic Dysplasia) 胸腔扩张术作为Jeune综合征(窒息性胸腔发育不良)的救命手术

Congenital anomalies Pub Date : 1993-12-01 DOI: 10.1111/j.1741-4520.1993.tb00540.x

R. Hashimoto, M. Esaki, T. Umeda, Tetsuyuki Sugitou, T. Hattori

引用次数: 1

Bronchial Branching Abnormalities and Emphysema‐like Changes in Mutant Rats Having Congenital Lobation Anomalies in the Lung 先天性肺叶异常突变大鼠的支气管分支异常和肺气肿样变化

Congenital anomalies Pub Date : 1993-12-01 DOI: 10.1111/j.1741-4520.1993.tb00538.x

H. Aoyama, S. Fujii, S. Teramoto

{"title":"Bronchial Branching Abnormalities and Emphysema‐like Changes in Mutant Rats Having Congenital Lobation Anomalies in the Lung","authors":"H. Aoyama, S. Fujii, S. Teramoto","doi":"10.1111/j.1741-4520.1993.tb00538.x","DOIUrl":"https://doi.org/10.1111/j.1741-4520.1993.tb00538.x","url":null,"abstract":"ABSTRACT The present study aimed at investigating in fpl/fpl mutant rats survived to adulthood 1) whether bronchial branching abnormalities were the primary defects of pulmonary lobation anomalies, and if this was the case, 2) whether these anomalies could lead to respiratory dysfunction. Examination of corrosion casts made from the malformed lungs of adult fpl/fpl rats revealed a variety of branching abnormalities in the right bronchial tree, such as ventral ramification of the middle lobar bronchus, abnormal curvature of the intermediate lobar bronchus, and positional abnormalities of the middle lobar bronchus and first segmental bronchus of the intermediate lobar bronchus, while reduction in the number of segmental bronchi was the only minor abnormality found in the left lung. These results conformed to our previous observations in which the main manifestation of the fpl mutation was restricted to the right lung lobes, and indicated that the primary defect of this malformation was bronchial branching abnormalities. In these rats, stenosis of the trachea, right and left principal bronchi, and some lobar and segmental bronchi also became evident by calipering their circumference. Histopathological examination of the lungs revealed abnormally expanded airspaces accompanied by destruction of alveolar walls and macrophage infiltration in aged fpl/fpl rats. These observations suggest that fpl/fpl rats suffer emphysema‐like respiratory dysfunction with advancing age from pulmonary lobation anomalies conforming to tracheal and bronchial malformations.","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1993-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80234782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Chromosomally Abnormal Gametes as a Cause of Developmental and Congenital Anomalies in Humans * 染色体异常配子作为人类发育和先天性异常的原因*

Congenital anomalies Pub Date : 1993-09-30 DOI: 10.1111/j.1741-4520.1994.tb00266.x

Y. Kamiguchi, H. Tateno, K. Mikamo

引用次数: 20

New Approach in Behavioral Teratology—Experimental Study on FAS * 行为畸形学的新途径——FAS的实验研究*

Congenital anomalies Pub Date : 1993-03-01 DOI: 10.1111/j.1741-4520.1993.tb00508.x

M. Omoto

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引用次数: 0

In Memorium Ujihiro Murakami (1910‐1992)

Congenital anomalies Pub Date : 1993-03-01 DOI: 10.1111/j.1741-4520.1993.tb00506.x

亀山義郎

引用次数: 0

Renal Cystic Disease : Classification and Pathogenesis * 肾囊性疾病:分类与发病机制*

Congenital anomalies Pub Date : 1993-03-01 DOI: 10.1111/j.1741-4520.1993.tb00507.x

J. Bernstein

引用次数: 2

Reviewers 评论家

Congenital anomalies Pub Date : 1992-10-01 DOI: 10.1109/ICDAR.2005.202

A. Abdoli, Amir Abe, Y. Abe, Yuki Ahmad, Wasim Akai, Takuya Albrechtsen, Susanne Aoto, Kazushi Baba

{"title":"Reviewers","authors":"A. Abdoli, Amir Abe, Y. Abe, Yuki Ahmad, Wasim Akai, Takuya Albrechtsen, Susanne Aoto, Kazushi Baba","doi":"10.1109/ICDAR.2005.202","DOIUrl":"https://doi.org/10.1109/ICDAR.2005.202","url":null,"abstract":"Abdallah, Anas Abdoli, Amir Abe, Yu Abe, Yuki Ahmad, Wasim Akai, Takuya Albrechtsen, Susanne Aoto, Kazushi Baba, Yoshiyuki Belaaloui, Ghania Bruno, Marino Cakmak, Ahmet Coppedè, Fabio Daikoku, Takiko Dangel, Joanna Eamsobhana, Perajit Fadiloglu, Erdem Fijałkowska, Marta Fujii, Sakiko Fujiwara, Kumiko Fujiwara, Michio Fukami, Maki Fukuda, Shuichi Fukushima, Wakaba Furukawa, Satoshi Guo, Hong Hamanoue, Haruka Hatta, Toshihisa Hayashi, Shin Hidaka, Nobuhiro Hojo, Hitoshi Icenogle, Joseph Imura, Hideto Inamura, Noboru Inoue, Ken Io, Shingo Iseki, Sachiko Ishii, Yoichiro Kalanlar, Bilge Kaname, Tadashi Kanda, Shoichiro Kapczuk, Karina Kawaki, Harumi Kosho, Tomiki Kumar, Delhi Kurosawa, Kenji Leung, Wing Cheong Lima, Mario Malinger, G Maluf, Sharbel Mayama, Michinori Miura, Kenichiro Miyake, Hidehiko Miyake, Noriko Miyata, Takaki Mizuno, Seiji Morales-Demori, Raysa Morisada, Naoya Mun, Goo-Hyun Muroya, Koji Nagasaki, Keisuke Nakajima, Yuji Natsume, Nagato Ndou, Robert Ngongang, Cedrik Nishigaki, Masakazu Nishigori, Hidekazu Nishijyo, muneko Nishimura, Gen Numabe, Hironao Ogawa, Masanobu Ogawa, Takuya Okada, Toshiya Okamoto, Nobuhiko Otani, Hiroki Perez, Ana Pruetz, Jay D Sago, Haruhiko Saitsu, Hirotomo Santen, Gijs Saralahti, Anni Sawada, Kazuhiko Sawai, Hideaki Sert, Ahmet Shibasaki, Jun Shimizu, Kenji Shimojima, Keiko SM, Balaji Suzuki, Rie Takabayashi, Shuji Takagi, Masaki Takahashi, Satoru Takakuwa, Tetsuya Takechi, Masaki Telli, Onur Thakur, Varsha Tolarova, Marie Tsuji, Michiko Udagawa, Jun Uehara, Tomoko van Rijn, Jorik Vora, Siddharth Yamada, Gen Yamada, Takahiro Yamada, Tomohiro Yamada, Yosuke Yamamoto, Toshiyuki Yamanaka, Michiko Yamataka, Atsuyuki Yasui, Yoshitomo Yoshihashi, Hiroshi Yoshiki, Atsushi Yuan, Zhengwei Zhu, Lan DOI: 10.1111/cga.12447","PeriodicalId":93953,"journal":{"name":"Congenital anomalies","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80386952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0