{"title":"HbaI genetic variant of APOE as an epidemiological factor for post COVID-19 cognitive impairment in the Amerindian population of Oaxaca.","authors":"Carlos E Cabrera-Pivaral","doi":"10.24875/CIRU.22000362","DOIUrl":"https://doi.org/10.24875/CIRU.22000362","url":null,"abstract":"","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 2","pages":"234-235"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Domínguez-Rodas, David A López-de la Mora, Nory O Dávalos-Rodríguez, Sergio A Ramírez-García, Ana R Rincón-Sánchez, Rufina Guzmán-López, Santiago Landeta-Velázquez, Carlos E Cabrera-Pivaral
{"title":"Clinical detection and description of the socio-demographic characteristics of the SARS-CoV-2 omicron variant in the population of the Sierra Sur of Oaxaca.","authors":"José Domínguez-Rodas, David A López-de la Mora, Nory O Dávalos-Rodríguez, Sergio A Ramírez-García, Ana R Rincón-Sánchez, Rufina Guzmán-López, Santiago Landeta-Velázquez, Carlos E Cabrera-Pivaral","doi":"10.24875/CIRU.22000397","DOIUrl":"https://doi.org/10.24875/CIRU.22000397","url":null,"abstract":"","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 1","pages":"124-126"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on SARS-CoV-2 genome and spike protein, COVID-19, and efficacy of vaccines.","authors":"Rujittika Mungmunpuntipantip, Viroj Wiwanitkit","doi":"10.24875/CIRU.23000200","DOIUrl":"https://doi.org/10.24875/CIRU.23000200","url":null,"abstract":"","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 1","pages":"127"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144011053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tratado sobre pandemias: discusiones preliminares.","authors":"Miguel Gallegos","doi":"10.24875/CIRU.24000077","DOIUrl":"https://doi.org/10.24875/CIRU.24000077","url":null,"abstract":"","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 2","pages":"238-239"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rogelio Sancho-Hernández, Rubén E Carlos-Corona, Lizbéth Solorio-Rodríguez
{"title":"Slide tracheoplasty without cardiopulmonary bypass for the treatment of long and complex congenital stenosis: case report and review of the literature.","authors":"Rogelio Sancho-Hernández, Rubén E Carlos-Corona, Lizbéth Solorio-Rodríguez","doi":"10.24875/CIRU.22000311","DOIUrl":"10.24875/CIRU.22000311","url":null,"abstract":"<p><p>Congenital tracheal stenosis is an entity that causes acute airway obstruction and is associated with high morbidity and mortality due to diagnostic delay and its accompanying comorbidity. Slide tracheoplasty is the procedure of choice that traditionally requires the use of cardiopulmonary bypass to facilitate the tracheal reconstruction technique. There are no national reports of this tracheoplasty. With a modification to the original description, the surgical technique is described and a case report executed without the use of cardiopulmonary bypass. A review of the literature is proposed to guide the comprehensive approach and treatment.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 2","pages":"224-230"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical study of Shenqi Fuzheng decoction directional penetration for the treatment of cancer pain in advanced lung cancer patients.","authors":"Shuang Wu, Jiachen Xi, Zhongliang Liu, Yaping Ding","doi":"10.24875/CIRU.24000209","DOIUrl":"https://doi.org/10.24875/CIRU.24000209","url":null,"abstract":"<p><strong>Objective: </strong>The study aimed at analyzing the effect of Shenqi Fuzheng Decoction directional penetration for treating advanced lung cancer patients with cancer-related pain.</p><p><strong>Method: </strong>Eighty-six cases with advanced lung cancer received in Zhoushan Hospital of Traditional Chinese Medicine from June 2022 to June 2023 were divided randomly into a study group (n = 43) and control group (n = 43). Two groups were treated with the same conservative treatment plan, on the basis of which the control group treated with placebo, and study group received Shenqi Fuzheng Decoction directional penetration treatment. The cancer-related pain intensity, analgesic onset time, the frequency of pain outbreak, and analgesic duration were assessed and recorded. Before and after treatment, the cancer-related fatigue, quality of life, and Karnofsky Performance Status (KPS) score were assessed in two groups. Moreover, the adverse reactions of two groups during treatment were recorded.</p><p><strong>Results: </strong>Compared to the control group, the cancer-related pain intensity of the study group was reduced, the analgesic onset time was shortened, the frequency of pain outbreak was reduced, and the analgesic duration was prolonged (p < 0.05). After treatment, Piper Fatigue Scale (PFS) scores in the study group were lower than the control group, and the generic quality of life inventory-74 (GQOLI-74) and KPS scores in the study group were higher than the control group (p < 0.05). During the treatment period, no significant adverse reactions were observed in both groups (p > 0.05).</p><p><strong>Conclusion: </strong>Shenqi Fuzheng Decoction directional penetration treatment has a remarkable effect in advanced lung cancer patients with cancer pain, which can relief the pain intensity, prolong the duration of pain relief, reduce the number of pain attacks, relieve patients' cancer-related fatigue, and improve patients' life quality and health status.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 1","pages":"6-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ünal T Öztürk, Hatice S Y Cömert, Gül Şalcı, Ahmet Alver, Sevdegül A Mungan, Neslihan Sağlam, Şeniz Erdem, Serdar Karakullukçu, Mustafa İmamoğlu, Haluk Sarıhan
{"title":"Evaluation of the effectiveness of human breast milk exosomes in experimental testicular torsion-detorsion injury model.","authors":"Ünal T Öztürk, Hatice S Y Cömert, Gül Şalcı, Ahmet Alver, Sevdegül A Mungan, Neslihan Sağlam, Şeniz Erdem, Serdar Karakullukçu, Mustafa İmamoğlu, Haluk Sarıhan","doi":"10.24875/CIRU.23000462","DOIUrl":"https://doi.org/10.24875/CIRU.23000462","url":null,"abstract":"<p><strong>Objective: </strong>Our aim was to examine the effectiveness of human breast milk exosomes in treating testicular torsion.</p><p><strong>Methods: </strong>Rats were divided randomly into three equal groups. Group 1 was our control group. A torsion/detorsion model was created for the rats in Group 2. After the torsion/detorsion model, 1 mg/kg intraperitoneally human breast milk exosomes were given 30 min before detorsion in Group 3. All testicles were removed at the 6<sup>th</sup> h of the experiment, for biochemical and histopathological examination.</p><p><strong>Results: </strong>There was a statistically significant decrease in Group 3 MDA values compared to Group 2. When Group 3 and Group 2 SOD and CAT values were compared, it was seen that these values were higher in Group 3. Histopathologically a statistically significant difference was found in Group 3 compared to Group 1 and Group 2 in terms of ischemia/reperfusion injury.</p><p><strong>Conclusion: </strong>We have shown that human breast milk exosomes in testicular torsion do not completely prevent reperfusion injury but significantly preserve testicular tissue.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 2","pages":"151-157"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Azizoglu, Asli P Zorba-Yildiz, Hazal Yilmaz, Goncagul Yurtbay, Gonul Catli, Giray Yavuz, Arzu D Yavas, Makbule Eren, Merve Arici, Vedat Goken, Selcuk Yasar, Hakan Darici
{"title":"Regenerative medicine in surgery: stem cells and exosome applications.","authors":"Mustafa Azizoglu, Asli P Zorba-Yildiz, Hazal Yilmaz, Goncagul Yurtbay, Gonul Catli, Giray Yavuz, Arzu D Yavas, Makbule Eren, Merve Arici, Vedat Goken, Selcuk Yasar, Hakan Darici","doi":"10.24875/CIRU.24000620","DOIUrl":"https://doi.org/10.24875/CIRU.24000620","url":null,"abstract":"<p><p>This review outlines the role of regenerative medicine in surgical applications, focusing on stem cells and exosomes. Among the most important features of stem cells are their unique ability to differentiate into various cell types, which make them stand out in regeneration and repair. Recent advances highlight the effectiveness of not only these cells themselves but also the exosomes, the nano-sized extracellular vesicles they produce, in this regeneration. On the other hand, exosomes assure additional advantages concerning low immunogenicity and high bioavailability but have raised problems in standardization and safety. In fact, the introduction of these stem cell and exosome technologies is changing the management of surgical pathologies and offering hope for diseases hitherto considered incurable. In this review, the use of stem cell therapies in various surgical diseases is categorized and examined, their clinical importance is emphasized, and the deficiencies in research studies are indicated. Therefore, the results are promising for treatments, but more standardized protocols and expanded research on long-term safety and effectiveness are needed.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 1","pages":"86-104"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between complete blood count parameters and histologically proven acute appendicitis.","authors":"Rawan AlHarmi","doi":"10.24875/CIRU.23000317","DOIUrl":"https://doi.org/10.24875/CIRU.23000317","url":null,"abstract":"<p><strong>Objectives: </strong>The objective of the study was to assess the role of complete blood count (CBC) parameters in the detection of acute appendicitis (AA) severity in children and adults.</p><p><strong>Method: </strong>This is a retrospective analytic cross-sectional study on cases operated for AA between June 1, 2020, and February 28, 2021, in Salmaniya Medical Complex, Bahrain. Patients of all ages and genders were included in the study. Exclusion criteria included other appendiceal pathologies, the presence of another intraoperative pathology that is the likely cause of abdominal pain, normal appendix, and missing parameters. Data included patient demographics, CBC parameters, and histopathology. Patients were divided into groups based on age and severity of AA.</p><p><strong>Results: </strong>A total of 569 patients were included in the study. Ages ranged from 4 to 75 years. Majority of the patients were males (74.87%) and adults (89.81%). A quarter of the patients were diagnosed with complicated AA, while the rest had simple AA. A statistically significant difference was observed between adults with complicated and simple AA in white blood cell (WBC), absolute neutrophil count (ANC), absolute lymphocyte count (ALC), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). None of the parameters was statistically significant in children.</p><p><strong>Conclusion: </strong>WBC, ANC, ALC, NLR, and PLR can be useful parameters in the discrimination between complicated and simple AA in adults. PLR was found to be the least predictive.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 1","pages":"28-34"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}