Jesús J Rosales-de la Rosa, Salma C Hernández-Orona, Andrea Escamilla-López, Paulina Alcocer-González-Camarena, Mario Vilatobá-Chapa, Alejandro Ramírez-Del Val, Miguel A Miguel A, Ismael Domínguez-Rosado
{"title":"[Initial experience of minimally invasive liver resection at a reference center in Mexico].","authors":"Jesús J Rosales-de la Rosa, Salma C Hernández-Orona, Andrea Escamilla-López, Paulina Alcocer-González-Camarena, Mario Vilatobá-Chapa, Alejandro Ramírez-Del Val, Miguel A Miguel A, Ismael Domínguez-Rosado","doi":"10.24875/CIRU.24000289","DOIUrl":"https://doi.org/10.24875/CIRU.24000289","url":null,"abstract":"<p><strong>Objective: </strong>Minimally invasive liver resection is employed worldwide for the management of benign and malignant liver lesions. There is no description of postoperative outcomes in the Mexican population. This study aims to report the initial experience in Mexico.</p><p><strong>Method: </strong>A cross-sectional analysis was performed on 20 patients undergoing minimally invasive liver resection between 2018 and 2024 at a reference center in Mexico. Quantitative variables are reported as mean ± standard deviation or median with range, while qualitative variables as frequencies with percentages.</p><p><strong>Results: </strong>The most frequently performed procedures were left lateral sectionectomy in five cases, 7/20 were classified as intermediate and 10/20 as expert difficulty, according to the IWATE scoring criteria. Additional results included major complication (35%), intrahospital mortality (5%), surgical reintervention (0%), median hospital length of stay (6 [3-54] days) and R0 resection rate (76.9%).</p><p><strong>Conclusions: </strong>The initial experience of minimally invasive liver resection in Mexico includes complex cases, with great difficulty according to the IWATE criteria, with comparable R0 resection rates.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleeve gastrectomy improves HDL function examined by Apo-A1 and atherogenic indices in non-diabetic obese patients.","authors":"Onur Ozener, Esin Yilmaz, Necat Yilmaz, Burhan Mayir","doi":"10.24875/CIRU.23000400","DOIUrl":"https://doi.org/10.24875/CIRU.23000400","url":null,"abstract":"<p><strong>Objective: </strong>Dysregulation of lipid metabolism can be one of the pathophysiological mechanisms linking high-density lipoprotein cholesterol (HDL-C) dysfunction to obesity. The aim of the study is to show possible changes in lipid metabolism with atherogenic indices in obese patients after sleeve gastrectomy (SG) surgery.</p><p><strong>Method: </strong>Thirty patients who had SG surgery for obesity were included in the prospective study. The atherogenic risk indices were calculated pre-operatively, at 3 and 6 months post-operatively. Furthermore, serum paraoxonase-1 (PON-1), apolipoprotein-A1 (Apo-A1), and platelet-activating factor acetylhydrolase (PAF-AH) levels, amount of oxidized low-density lipoprotein (Ox-LDL) was measured.</p><p><strong>Results: </strong>We observed improvement in atherogenic risk indices and improved HDL-C functionality after SG. Increases were observed in HDL-C and HDL-C-related Apo-A1 levels 6 months after obesity surgery. Besides, the amount of serum triglycerides (TGs), PON-1 activity, and atherogenic risk indices decreased significantly within 6 months.</p><p><strong>Conclusion: </strong>As far as we know, there is no study in the literature examining the dynamic changes in SG and PON-1, PAF-AH, Apo-A1, and Ox-LDL parameters. This preliminary study dynamically detected improvement in HDL-C function and reduction in atherogenic risk indices after SG.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yildiray Yildiz, Veysel Bayburtluoglu, Eda Tokat, Ali K Yildiz, Aykut Ucar, Sebnem Erdinc, Omer G Doluoglu
{"title":"Changes in prostate specific antigen value in patients with COVID-19.","authors":"Yildiray Yildiz, Veysel Bayburtluoglu, Eda Tokat, Ali K Yildiz, Aykut Ucar, Sebnem Erdinc, Omer G Doluoglu","doi":"10.24875/CIRU.22000479","DOIUrl":"https://doi.org/10.24875/CIRU.22000479","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate changes in prostate-specific antigen (PSA) values in patients with coronavirus disease 2019 (COVID-19).</p><p><strong>Method: </strong>Male patients who were admitted to our flu outpatient clinic with cough, fever, weakness, and bone and joint pain were evaluated. The acute phase reactants of erythrocyte sedimentation rate, C-reactive protein, ferritin, and fibrinogen were measured both at the time the patients first presented at the clinic and 1 month after recovery from COVID-19 infection. PSA and free PSA were also measured at the same time. The difference in acute phase reactants and PSA values during active COVID-19 infection and after recovery was assessed using the paired samples t-test.</p><p><strong>Results: </strong>The mean PSA values of the patients were 2.73 ± 3.7 μg/L in the period of active infection, and 2.04 ± 2.32 μg/L 1 month later (p = 0.12). In the 29 patients with PSA values in the gray zone, the PSA values were determined as 6.6 ± 4.4 μg/L during infection and 4.1 ± 2.9 μg/L after treatment (p = 0.001).</p><p><strong>Conclusion: </strong>The results of this study showed that PSA values in the gray zone during COVID-19 infection decreased after treatment when the patient recovered.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aykut Demirci, Tuncel Uzel, Abdullah Bolat, Halil Başar
{"title":"Do the ınflammatory markers have a prognostic role in an elderly patient population diagnosed with non-muscle ınvasive bladder cancer?","authors":"Aykut Demirci, Tuncel Uzel, Abdullah Bolat, Halil Başar","doi":"10.24875/CIRU.23000278","DOIUrl":"10.24875/CIRU.23000278","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether the systemic immune-inflammation index (SII), neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and De-Ritis ratio (DRR) are determinants of progression-free survival (PFS), recurrence-free survival (RFS) and overall survival (OS) in patients aged ≥ 70 years diagnosed with non-muscle invasive bladder cancer (NMIBC).</p><p><strong>Method: </strong>The study included 173 elderly patients diagnosed with NMIBC between January 2015 and March 2022. The clinical and pathological data of the patients were examined. Cox regression analysis was performed.</p><p><strong>Results: </strong>The patient's mean age was 75.6 ± 4.57 years. A statistically significant correlation was determined between higher mean NLR, PLR, and SII values and PFS (p = 0.04, p = 0.009, and p = 0.007, respectively) and OS (p = 0.001, p = 0.003, and p < 0.001, respectively). The multivariate analysis results showed that tumor size (≥ 3 cm) and PLR (> 144.6) were independent risk factors for PFS (HR: 2.09, p = 0.03; HR:3.2, p = 0.01, respectively), the presence of multiple tumors for RFS (HR: 1.73, p = 0.01), and comorbid diseases for OS (HR: 2.18, p = 0.006).</p><p><strong>Conclusion: </strong>Inflammatory parameters were found to have no independent effects on RFS and OS in patients of advanced age with NMIBC, and only PLR could be used to predict PFS.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":" ","pages":"202-210"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kemine Uzel, Seda E Keskin, Filiz Bilir, Merve Gokbayrak, Gulhan Demir, Naci Cine, Gupse Turan, Aydın Corakcı, Hakan Savlı
{"title":"Comparison of cytogenetic and molecular features observed in endometrial cancers: known clinic and difficulties in treatment.","authors":"Kemine Uzel, Seda E Keskin, Filiz Bilir, Merve Gokbayrak, Gulhan Demir, Naci Cine, Gupse Turan, Aydın Corakcı, Hakan Savlı","doi":"10.24875/CIRU.23000328","DOIUrl":"10.24875/CIRU.23000328","url":null,"abstract":"<p><strong>Objective: </strong>Understanding the relationship between genetic structure and the molecular changes involved in endometrial cancer (EC) provides an opportunity to personalize treatments and incorporate targeted therapies.</p><p><strong>Method: </strong>We compared cytogenetic and molecular features observed in tumoral and adjacent healthy tissue endometrium samples in EC patients.</p><p><strong>Results: </strong>Non-clonal chromosome aberrations (NCCAs) frequently in patients with EC, especially in 10,15,17,22, X chromosomes and were monitored in 73.7%, clonal chromosomal alterations were observed in 26.3% of the patients. Down POLE gene expression in 42.1%, up p53gene expression in 57.9%, PTEN down-regulation in 47.3%, down ARID1A gene expression in 42.1%, PIK3CA up-regulation was observed in 68% of patients.</p><p><strong>Conclusion: </strong>The up-regulation of tumor suppressor genes in our study shows that not only these genes are involved but also different pathways and factors play a role in tumorigenesis. Furthermore, an increased number of NCCAs shows an essential role in the development of ECs.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":" ","pages":"138-144"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hulya Y Ak, Kubra Taskin, Merve B Yediyildiz, Irem Durmus, Ozlem Sezen, Baris Sandal, Banu Cevik
{"title":"Comparative analysis of PECS-2 and ESP for acute and chronic pain control in breast-conserving surgery. A prospective study.","authors":"Hulya Y Ak, Kubra Taskin, Merve B Yediyildiz, Irem Durmus, Ozlem Sezen, Baris Sandal, Banu Cevik","doi":"10.24875/CIRU.24000223","DOIUrl":"10.24875/CIRU.24000223","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to compare the effects of Pectoral Nerve Block 2 (PECS-2) and Erector Spinae Plane Block (ESP), which are accepted to have an effect on post-operative pain control after breast cancer surgery, on both acute and chronic pain.</p><p><strong>Method: </strong>In this double-blind, prospective, randomized study, patients were randomized using a sealed envelope method into two groups: those who underwent PECS-2 (Group P) and those who underwent ESP (Group E) before extubation at the end of the operation. The numerical rating scale (NRS) of patients was queried by a blinded researcher at post-operative 1, 2, 6, 12, and 24 h. In addition, patients were queried for the presence of chronic pain at the 3rd month using NRS.</p><p><strong>Results: </strong>The NRS scores at 1 h and 2 h in Group P were significantly lower compared to Group E. There was no significant difference in NRS scores at 6 h, 12 h, and 24 h between the groups. The rate of chronic pain was similar between the groups.</p><p><strong>Conclusion: </strong>In this study examining the effects of ESP and PECS-2 on acute and chronic pain after BCS due to breast cancer, PECS-2 was associated with less post-operative pain.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":" ","pages":"145-150"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correspondence on incidence and factors associated with adverse reactions after the first dose of COVID-19 vaccine.","authors":"Amnuay Kleebayoon, Viroj Wiwanitkit","doi":"10.24875/CIRU.23000068","DOIUrl":"10.24875/CIRU.23000068","url":null,"abstract":"","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 3","pages":"333-334"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the role of pre-operative hemoglobin, albumin, lymphocyte, and platelet scores in predicting perioperative morbidity in rectal cancer patients.","authors":"Mehmet F Erol, Oğuzhan F Ay, Enes Karademir","doi":"10.24875/CIRU.24000185","DOIUrl":"10.24875/CIRU.24000185","url":null,"abstract":"<p><strong>Objective: </strong>Our study aims to explore the predictive value of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score, calculated from routine blood tests measuring HALP levels, for perioperative morbidity in rectal cancer surgery patients.</p><p><strong>Method: </strong>We conducted a retrospective study focusing on patients who underwent elective rectal cancer surgery from January 2017 to September 2023. The study analyzed demographic, clinical, and laboratory data, including the HALP score, to assess its correlation with perioperative morbidity using logistic and linear regression analyses.</p><p><strong>Results: </strong>Univariate analysis showed no correlation between the HALP score and perioperative morbidity. Intriguingly, an increase of each centimeter in tumor size was associated with a significant reduction in the HALP score (p = 0.042), and operation time exhibited an inverse relationship with HALP scores (p < 0.001). Further, our study identified sex (male, p = 0.017) and age (> 65, p = 0.016) as significant predictors of perioperative morbidity.</p><p><strong>Conclusions: </strong>Our study found that pre-operative HALP scores did not significantly predict perioperative morbidity or local recurrence in rectal cancer surgery, challenging their presumed prognostic value. However, a notable association was observed between higher HALP scores, reduced tumor size, and shorter operative times, suggesting a potential indirect relationship of HALP in surgical outcomes.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 3","pages":"273-280"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Rivas-Sucari, José L Rodríguez-Eguizabal, Henry C Rivas-Sucari
{"title":"Measuring the desire to eat after pandemic.","authors":"David Rivas-Sucari, José L Rodríguez-Eguizabal, Henry C Rivas-Sucari","doi":"10.24875/CIRU.24000088","DOIUrl":"10.24875/CIRU.24000088","url":null,"abstract":"","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 3","pages":"339-340"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fabio A Varón-Vega, Adriana Rincón, Eduardo Tuta-Quintero, Catalina González-Avilés, Leidy P Prada, Luis J Téllez
{"title":"Survival analysis in a high-altitude lung transplant program: insights from a real-life observational study.","authors":"Fabio A Varón-Vega, Adriana Rincón, Eduardo Tuta-Quintero, Catalina González-Avilés, Leidy P Prada, Luis J Téllez","doi":"10.24875/CIRU.24000076","DOIUrl":"10.24875/CIRU.24000076","url":null,"abstract":"<p><strong>Objective: </strong>Survival in lung transplantation (LT) may be influenced by recipient-related variables, donor factors, donor-recipient interaction, surgical approach, and medical center expertise. The objective of this study was to describe the sociodemographic, clinical characteristics, and survival of patients who have undergone LT.</p><p><strong>Method: </strong>We conducted an observational analysis between 2014 and 2022. Survival was calculated using the Kaplan-Meier method at the 1<sup>st</sup>, 3<sup>rd</sup>, and 5<sup>th</sup> years of follow-up post-transplantation.</p><p><strong>Results: </strong>We analyzed data from 50 subjects, of whom 56% (28/50) were men, with a median age of 54 years (interquartile range: 39-59). The unadjusted survival rates post lung transplantation were 81.4% at 12-months, 65.8% at 3-years, and 53.6% at 5-years. Excluding mortality attributed to COVID-19, survival rates were 78.2% at 12-months, 68.8% at 3-years, and 63.5% at 5-years. The survival of pulmonary fibrosis with a non-usual interstitial pneumonia (N-UIP) pattern was 85% at 1 year and 54% at 5 years, while pulmonary fibrosis with a usual interstitial pneumonia (UIP) pattern demonstrated a solid survival rate of 80% at 1 year and 60% at 5 years.</p><p><strong>Conclusions: </strong>Patients with pulmonary fibrosis with a N-UIP pattern demonstrated superior survival after 1 year of follow-up, while those with pulmonary fibrosis with a UIP pattern described the highest survival at the 5<sup>th</sup> year. COVID-19 decreased long-term survival in transplant patients.</p>","PeriodicalId":93936,"journal":{"name":"Cirugia y cirujanos","volume":"93 3","pages":"267-272"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}