Bulletin du cancerPub Date : 2024-11-13DOI: 10.1016/j.bulcan.2024.09.004
Solène Grosse, Catherine Genestie, Stéphanie Scherier, Amandine Maulard, Patricia Pautier, Alexandra Leary, Judith Michels, Sophie Espenel, Thomas Dabreteau, Philippe Morice, Sébastien Gouy
{"title":"[Practical application of the 2023 FIGO classification for endometrial cancer].","authors":"Solène Grosse, Catherine Genestie, Stéphanie Scherier, Amandine Maulard, Patricia Pautier, Alexandra Leary, Judith Michels, Sophie Espenel, Thomas Dabreteau, Philippe Morice, Sébastien Gouy","doi":"10.1016/j.bulcan.2024.09.004","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.09.004","url":null,"abstract":"<p><p>Since the last FIGO classification in 2009, numerous studies and recommendations have contributed to improving the management of endometrial cancer. The introduction of molecular classification (including POLE, MMR, and P53 status) has enabled better categorization of these cancers by defining specific patient groups, thus allowing for more tailored surgical management and adjuvant treatment. The data and analyses on molecular and histological classification developed in the 2021 guidelines from the European Societies of Gynecologic Oncology (ESGO), Radiation Therapy and Oncology (ESTRO), and Anatomical Pathology (ESP) have been utilized to develop the new 2023 FIGO classification for endometrial cancer. We are witnessing an evolution of the FIGO classification, shifting from a purely anatomical classification to a risk-based classification. It is important in pathology reports to specify the histological type of the tumor, the grade for endometrioid tumors, the presence or absence of lymphovascular space invasion, and the extent of the tumor (myometrial invasion, involvement of the serosa, cervix, vagina, adnexa, or neighboring organs). These essential points are included in the 2023 FIGO classification and will enable precise staging of the tumor. This article aims to clarify and simplify the classification of patients according to the new 2023 FIGO classification for endometrial cancer.</p>","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-11-06DOI: 10.1016/j.bulcan.2024.07.012
Michel D'Incan
{"title":"[Cutaneous T-cell lymphomas].","authors":"Michel D'Incan","doi":"10.1016/j.bulcan.2024.07.012","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.07.012","url":null,"abstract":"<p><p>Primitive cutaneous T-cell lymphomas are lymphomas clinically restricted to skin at diagnosis in opposite to skin localizations of systemic lymphomas. Cutaneous T-cell lymphomas are the most frequent. Beside mycosis fungoides and related forms, CD30+ lymphoproliferations (lymphomatoid papulosis, anaplastic large cell primitive cutaneous T-cell lymphomas) and erythrodermic T-cell lymphomas which constitute the main entities, other rare lymphomas are described: panniculitis like alpha/beta lymphoma, gamma/delta lymphoma, epidermotropic CD8+ aggressive lymphoma, small to medium T-cell lymphomas and acral CD8+ lymphoproliferations. Clinical skin examination and skin biopsy examination are crucial for diagnosis but recent advances in molecular genetics bring promising tools for diagnostic. Thanks to international cooperative groups, treatment of mycosis fungoides, CD30+ lymphoproliferations and erythrodermic lymphomas is now well established which is not the case for the other entities. Treatments may be classified in five categories: skin directed therapies, systemic non-chemotherapeutic treatments, immunomodulators, targeted immunotherapies and chemotherapies.</p>","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-10-24DOI: 10.1016/j.bulcan.2024.07.011
Victoria Min, Nadège Corradini, Nicolas Macagno, Daniel Orbach, Yves Reguerre, Philippe Petit, Jean-Yves Blay, Arnauld Verschuur
{"title":"Gastrointestinal stromal tumours (GIST) in children: An update of this orphan disease.","authors":"Victoria Min, Nadège Corradini, Nicolas Macagno, Daniel Orbach, Yves Reguerre, Philippe Petit, Jean-Yves Blay, Arnauld Verschuur","doi":"10.1016/j.bulcan.2024.07.011","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.07.011","url":null,"abstract":"<p><strong>Background: </strong>Gastrointestinal stromal tumours (GIST) are tumours of the digestive tract that mainly develop in adults. Recommendations for the management of GIST in pediatrics are limited.</p><p><strong>Material and methods: </strong>We performed an updated review of the literature serving as a basis for the development of diagnostic and therapeutic recommendations for GIST in children and young adults (YA).</p><p><strong>Results: </strong>GIST in pediatric population can have a sporadic presentation but occur more often in a syndromic and/or familial context. Currently more than 170 cases of sporadic GIST or in association with Carney-Stratakis syndrome or Carney's triad family cases of familial GIST have been described in children and YA. These syndromes are frequently associated with germline or somatic alterations in a sub-unit of Succinate Dehydrogenase (SDH). In contrast, the frequency of somatic KIT and PDGFRα oncogene mutations (±15%) is significantly lower as compared to adults with GIST. The recommendations for the management of children with GIST are generally comparable to those used for adult patients, although certain biological differences influence the therapeutic attitude.</p><p><strong>Conclusions: </strong>International collaborations have been deployed in order to increase the clinical and biological knowledge of this orphan pathology in pediatrics.</p>","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-09-02DOI: 10.1016/j.bulcan.2024.07.001
Serge Évrard, Philippe Morice
{"title":"[Surgery and prophylaxis of cancer: Why everything is going to change?]","authors":"Serge Évrard, Philippe Morice","doi":"10.1016/j.bulcan.2024.07.001","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.07.001","url":null,"abstract":"","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-06-26DOI: 10.1016/j.bulcan.2024.04.015
Alexandra Nassar, Maria Conticchio, Marie-Julie Lardinois, Juliette Benedetti, Lisa Lartigau, Ugo Marchese, Stylianos Tzedakis, David Fuks
{"title":"[Prophylactic surgery for hepatic and biliary tumors].","authors":"Alexandra Nassar, Maria Conticchio, Marie-Julie Lardinois, Juliette Benedetti, Lisa Lartigau, Ugo Marchese, Stylianos Tzedakis, David Fuks","doi":"10.1016/j.bulcan.2024.04.015","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.04.015","url":null,"abstract":"<p><p>Benign tumors of the liver and biliary tract are rare entities, and some of them require surgical management to prevent their malignant transformation. Tumors from the biliary tract with malignant potential are treated either by hepatic resection, for mucinous cystic neoplasm and ciliated hepatic foregut cysts, or by biliary resections, for biliary papillary neoplasm and type I and IV choledochal cysts. The pathologies requiring prophylactic cholecystectomy are polyps larger than 10 mm, porcelain gallbladder and pancreaticobiliary maljunction. Finally, hepatocellular adenoma over 5cm, occurring in male patients, or exon 3 mutated beta-catenin, should lead to prophylactic resection by hepatic segmentectomy. This article describes these different pathologies and their management.</p>","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-05-16DOI: 10.1016/j.bulcan.2024.05.001
Julie Audet, Marc Berger, Johanne Cashman, Yves Chalandon, Laure Coulombel, Stéphane Flamant, Saghi Ghaffari, Sylvain Lefort, François Lemoine, Véronique Maguer-Satta, Franck E Nicolini, Christian Schmitt, Ivan Sloma, Ali Turhan
{"title":"Pr Connie J. Eaves (1944–2024).","authors":"Julie Audet, Marc Berger, Johanne Cashman, Yves Chalandon, Laure Coulombel, Stéphane Flamant, Saghi Ghaffari, Sylvain Lefort, François Lemoine, Véronique Maguer-Satta, Franck E Nicolini, Christian Schmitt, Ivan Sloma, Ali Turhan","doi":"10.1016/j.bulcan.2024.05.001","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.05.001","url":null,"abstract":"","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-05-15DOI: 10.1016/j.bulcan.2024.04.003
Perrine Côme, Pauline Rochefort, Lucas De Crignis, Aurélien Dupré
{"title":"[Prophylactic gastrectomy].","authors":"Perrine Côme, Pauline Rochefort, Lucas De Crignis, Aurélien Dupré","doi":"10.1016/j.bulcan.2024.04.003","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.04.003","url":null,"abstract":"<p><p>One to 3% of gastric cancers are secondary to genetic predisposition, notably hereditary diffuse gastric cancers (HDGC) caused by CDH1 gene mutations. According to French recommendations, in case of CDH1 gene mutation, a prophylactic total gastrectomy should be performed between 20 and 30 years old. This gastrectomy should remove all the gastric mucosa at both extremities (duodenal and esophageal sides). Histopathological examinations of prophylactic total gastrectomies in asymptomatic CDH1-mutated patients reveal microscopic foci of diffuse-type cancer in 90 to 100% of cases. Lymph node involvement and lympho-vascular invasion are extremely rare, justifying the use of a D1-only lymphadenectomy. In the context of prophylaxis, limited lymphadenectomy and the development of minimally invasive oesogastric surgery, the minimally invasive approach might be the preferred approach, in expert centers. Surgical outcomes seem to be similar to those after gastrectomy for cancer. Prophylactic total gastrectomy is the cornerstone of CGDH management, associated with multidisciplinary follow-up and mammary surveillance in women.</p>","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-05-15DOI: 10.1016/j.bulcan.2024.03.004
Maryse Karrer, Marie Bannier, Romain Arini, Christine Arnou, Joëlle André-Vert
{"title":"[Breast reconstruction: towards a better patient involvement for shared decision making after mastectomy].","authors":"Maryse Karrer, Marie Bannier, Romain Arini, Christine Arnou, Joëlle André-Vert","doi":"10.1016/j.bulcan.2024.03.004","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.03.004","url":null,"abstract":"","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bulletin du cancerPub Date : 2024-05-01DOI: 10.1016/j.bulcan.2024.03.007
François Guilhot
{"title":"[The need to set up a national register of adult cancers in France].","authors":"François Guilhot","doi":"10.1016/j.bulcan.2024.03.007","DOIUrl":"https://doi.org/10.1016/j.bulcan.2024.03.007","url":null,"abstract":"","PeriodicalId":93917,"journal":{"name":"Bulletin du cancer","volume":"8 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141051898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}