Biomedizinische Technik. Biomedical engineering最新文献_第5页

A portable household detection system based on the combination of bidirectional LSTM and residual block for automatical arrhythmia detection. 一种基于双向LSTM和残差块相结合的便携式家庭心律失常自动检测系统。

Biomedizinische Technik. Biomedical engineering Pub Date : 2023-09-29 Print Date: 2024-04-25 DOI: 10.1515/bmt-2021-0146

Zeqiong Huang, Shaohua Yang, Qinhong Zou, Xuliang Gao, Bin Chen

{"title":"A portable household detection system based on the combination of bidirectional LSTM and residual block for automatical arrhythmia detection.","authors":"Zeqiong Huang, Shaohua Yang, Qinhong Zou, Xuliang Gao, Bin Chen","doi":"10.1515/bmt-2021-0146","DOIUrl":"10.1515/bmt-2021-0146","url":null,"abstract":"Objectives: Arrhythmia is an important component of cardiovascular disease, and electrocardiogram (ECG) is a method to detect arrhythmia. Arrhythmia detection is often paroxysmal, and ECG signal analysis is time-consuming and expensive. We propose a model and device for convenient monitoring of arrhythmia at any time.Methods: This work proposes a model combining residual block and bidirectional long-term short-term memory network (BiLSTM) to detect and classify ECG signals. Residual blocks can extract deep features and avoid performance degradation caused by convolutional networks. Combined with the feature of BiLSTM to strengthen the connection relationship of the local window, it can achieve a better classification and prediction effect.Results: Model optimization experiments were performed on the MIT-BIH Atrial Fibrillation Database (AFDB) and MIT-BIH Arrhythmia Database (MITDB). The accuracy simulation results on both long and short signal was higher than 99 %. To further demonstrate the applicability of the model, validation experiments were conducted on MIT-BIH Normal Sinus Rhythm Database (NSRDB) and the Long-Term AF Database (LTAFDB) datasets, and the related recognition accuracy were 99.830 and 91.252 %, respectively. Additionally, we proposed a portable household detection system including an ECG and a blood pressure detection module. The detection accuracy was higher than 98 % using the collected data as testing set.Conclusions: Hence, we thought our system can be used for practical application.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"167-179"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41143269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computer aided detection of tuberculosis using two classifiers. 计算机辅助检测肺结核的两种分类器。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-09-26 Print Date: 2022-12-16 DOI: 10.1515/bmt-2021-0310

Abdullahi Umar Ibrahim, Fadi Al-Turjman, Mehmet Ozsoz, Sertan Serte

{"title":"Computer aided detection of tuberculosis using two classifiers.","authors":"Abdullahi Umar Ibrahim, Fadi Al-Turjman, Mehmet Ozsoz, Sertan Serte","doi":"10.1515/bmt-2021-0310","DOIUrl":"https://doi.org/10.1515/bmt-2021-0310","url":null,"abstract":"Tuberculosis caused by Mycobacterium tuberculosis have been a major challenge for medical and healthcare sectors in many underdeveloped countries with limited diagnosis tools. Tuberculosis can be detected from microscopic slides and chest X-ray but as a result of the high cases of tuberculosis, this method can be tedious for both microbiologist and Radiologist and can lead to miss-diagnosis. The main objective of this study is to addressed these challenges by employing Computer Aided Detection (CAD) using Artificial Intelligence-driven models which learn features based on convolution and result in an output with high accuracy. In this paper, we described automated discrimination of X-ray and microscopic slide images of tuberculosis into positive and negative cases using pretrained AlexNet Models. The study employed Chest X-ray dataset made available on Kaggle repository and microscopic slide images from both Near East university hospital and Kaggle repository. For classification of tuberculosis and healthy microscopic slide using AlexNet+Softmax, the model achieved accuracy of 98.14%. For classification of tuberculosis and healthy microscopic slide using AlexNet+SVM, the model achieved 98.73% accuracy. For classification of tuberculosis and healthy chest X-ray images using AlexNet+Softmax, the model achieved accuracy of 98.19%. For classification of tuberculosis and healthy chest X-ray images using AlexNet+SVM, the model achieved 98.38% accuracy. The result obtained has shown to outperformed several studies in the current literature. Future studies will attempt to integrate Internet of Medical Things (IoMT) for the design of IoMT/AI-enabled platform for detection of Tuberculosis from both X-ray and Microscopic slide images.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"513-524"},"PeriodicalIF":1.7,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40376835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Nano-material utilization in stem cells for regenerative medicine. 纳米材料在干细胞再生医学中的应用。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-09-14 Print Date: 2022-12-16 DOI: 10.1515/bmt-2022-0123

Darin Sawah, Maha Sahloul, Fatih Ciftci

{"title":"Nano-material utilization in stem cells for regenerative medicine.","authors":"Darin Sawah, Maha Sahloul, Fatih Ciftci","doi":"10.1515/bmt-2022-0123","DOIUrl":"https://doi.org/10.1515/bmt-2022-0123","url":null,"abstract":"The utilization of nanotechnology in regenerative medicine has been globally proven to be the main solution to many issues faced with tissue engineering today, and the theoretical and empirical investigations of the association of nanomaterials with stem cells have made significant progress as well. For their ability to self-renew and differentiate into a variety of cell types, stem cells have become popular candidates for cell treatment in recent years, particularly in cartilage and Ocular regeneration. However, there are still several challenges to overcome before it may be used in a wide range of therapeutic contexts. This review paper provides a review of the various implications of nanomaterials in tissue and cell regeneration, the stem cell and scaffold application in novel treatments, and the basic developments in stem cell-based therapies, as well as the hurdles that must be solved for nanotechnology to be used in its full potential. Due to the increased interest in the continuously developing field of nanotechnology, demonstrating, and pinpointing the most recognized and used applications of nanotechnology in regenerative medicine became imperative to provide students, researchers, etc. who are interested.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"429-442"},"PeriodicalIF":1.7,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40357391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optical bone densitometry insensitive to skin thickness. 光学骨密度测定法对皮肤厚度不敏感。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-09-14 Print Date: 2022-12-16 DOI: 10.1515/bmt-2021-0314

Kaname Miura, Anak Khantachawana, Tsuyoshi Wakamori, Hidenori Matsubara, Shigeo M Tanaka

{"title":"Optical bone densitometry insensitive to skin thickness.","authors":"Kaname Miura, Anak Khantachawana, Tsuyoshi Wakamori, Hidenori Matsubara, Shigeo M Tanaka","doi":"10.1515/bmt-2021-0314","DOIUrl":"https://doi.org/10.1515/bmt-2021-0314","url":null,"abstract":"Skin thickness, including the adipose layer, which varies from individual to individual, affects the bone density measurement using light. In this study, we proposed a method to measure skin thickness using light and to correct the bias caused by differences in skin thickness and verified the proposed method by experiments using a phantom. We measured simulated skin of different thicknesses and bovine trabecular bone of different bone mineral densities (BMDs) using an optical system consisting of lasers of 850 and 515 nm wavelengths, lenses, and slits. Although the slope of the light intensity distribution formed on the surface of the material when irradiated by the 850 nm laser is affected by the thickness of the skin phantom. The difference of the intensity distribution peaks (δy) between the 850 and 515 nm lasers was strongly correlated with the thickness of the skin phantom. The coefficient of determination between the measurements and the BMD was improved by correcting the 850 nm laser measurements with δy. This result suggests that the method is applicable to optical bone densitometry, which is insensitive to differences in skin thickness.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"503-512"},"PeriodicalIF":1.7,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40356421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Active cell capturing for organ-on-a-chip systems: a review. 芯片上器官系统的主动细胞捕获:综述。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-09-05 Print Date: 2022-12-16 DOI: 10.1515/bmt-2022-0232

Morteza Bayareh

引用次数: 1

In vitro thrombogenicity evaluation of rotary blood pumps by thromboelastometry. 用血栓弹性测量法评价旋转血泵的体外血栓形成性。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-08-31 Print Date: 2022-12-16 DOI: 10.1515/bmt-2022-0078

Mario Klein, Jana Christine Tack, Ilona Mager, Judith Maas, Thomas Schmitz-Rode, Jutta Arens, Ulrich Steinseifer, Johanna Charlotte Clauser

{"title":"In vitro thrombogenicity evaluation of rotary blood pumps by thromboelastometry.","authors":"Mario Klein, Jana Christine Tack, Ilona Mager, Judith Maas, Thomas Schmitz-Rode, Jutta Arens, Ulrich Steinseifer, Johanna Charlotte Clauser","doi":"10.1515/bmt-2022-0078","DOIUrl":"https://doi.org/10.1515/bmt-2022-0078","url":null,"abstract":"In vitro thrombogenicity tests for rotary blood pumps (RBPs) could benefit from assessing coagulation kinematics, as RBP design improves. In this feasibility study, we investigated if the method of thromboelastometry (TEM) is able to assess coagulation kinematics under the in vitro conditions of RBP tests. We conducted in vitro thrombogenicity tests (n=4) by placing Deltastream® DP3 pumps into test loops that were filled with 150 mL of slightly anti-coagulated porcine blood, adjusted to an activated clotting time (ACT) well below clinically recommended levels. Blood samples were taken at certain time points during the experiment until a continuous decrease in pump flow indicated major thrombus formation. Blood samples were analyzed for ACT, platelet count (PLT), and several TEM parameters. While visible thrombus formation was observed in three pumps, ACT indicated an ongoing activation of coagulation, PLT might have indicated platelet consumption. Unexpectedly, most TEM results gave no clear indications. Nonetheless, TEM clotting time obtained by non-anticoagulated and chemically non-activated whole blood (HEPNATEM-CT) appeared to be more sensitive for the activation of coagulation in vitro than ACT, which might be of interest for future pump tests. However, more research regarding standardization of thrombogenicity pump tests is urgently required.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"471-480"},"PeriodicalIF":1.7,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40331378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of weight gaining to lower limb joint moments: a gender-specific sit-to-stand analysis. 体重增加对下肢关节力矩的影响:一项针对性别的坐姿-站立分析。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-08-19 Print Date: 2022-12-16 DOI: 10.1515/bmt-2022-0085

Kasim Serbest

{"title":"Effects of weight gaining to lower limb joint moments: a gender-specific sit-to-stand analysis.","authors":"Kasim Serbest","doi":"10.1515/bmt-2022-0085","DOIUrl":"https://doi.org/10.1515/bmt-2022-0085","url":null,"abstract":"The prevalence of obesity, a worldwide health problem, is increasing. Obesity or overweight has significant effects, especially on lower limb biomechanics. Previous studies have investigated the biomechanical effects of weight gain on the knee and hip joints. These studies have been conducted on different individuals with normal weight and overweight. However, no investigation has been carried out between women and men in terms of weight gain. Females usually gain weight in the gluteal-femoral region, whereas males gain weight in the abdominal region. Due to this difference, it is thought that the effects of weight gain should be examined in a gender-specific manner. In this study, a link-segment model of the lower limb was created. Then the sit-to-stand movement was simulated according to female and male-specific weight gain scenarios. According to these results, weight gain in the abdominal region (men-specific) increases the ankle and knee joint moments more than weight gain in the gluteal-femoral region (women-specific). In obese scenarios for males and females, while the ankle and knee joint moment increases, the hip joint moment decreases. These results would be beneficial for considering biomechanical differences caused by gender-specific weight gain in rehabilitation processes and orthotic and prosthetic designs.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"481-489"},"PeriodicalIF":1.7,"publicationDate":"2022-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40634549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Corrigendum to: Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction. 开发一种新的可吸收羟基磷灰石骨替代物用于过临界尺寸的缺损重建:物理化学和生物学特性以及节段性兔尺骨重建的概念证明。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-06-28 DOI: 10.1515/bmt-2022-0188

Milutin Micic, Djordje Antonijevic, Sanja Milutinovic-Smiljanic, Dijana Trisic, Bozana Colovic, Dejana Kosanovic, Bogomir Prokic, Jugoslav Vasic, Slavoljub Zivkovic, Jelena Milasin, Vesna Danilovic, Marija Djuric, Vukoman Jokanovic

引用次数: 0

Designing and in vitro testing of a novel patient-specific total knee prosthesis using the probabilistic approach. 采用概率方法设计和体外测试一种新型患者特异性全膝关节假体。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-05-09 Print Date: 2022-08-26 DOI: 10.1515/bmt-2021-0136

İsmail H Korkmaz, İrfan Kaymaz, Ömer S Yıldırım, Fahri Murat, Halim Kovacı

{"title":"Designing and in vitro testing of a novel patient-specific total knee prosthesis using the probabilistic approach.","authors":"İsmail H Korkmaz, İrfan Kaymaz, Ömer S Yıldırım, Fahri Murat, Halim Kovacı","doi":"10.1515/bmt-2021-0136","DOIUrl":"https://doi.org/10.1515/bmt-2021-0136","url":null,"abstract":"In order to prevent failure as well as ensure comfort, patient-specific modelling for prostheses has been gaining interest. However, deterministic analyses have been widely used in the design process without considering any variation/uncertainties related to the design parameters of such prostheses. Therefore, this study aims to compare the performance of patient-specific anatomic Total Knee Arthroplasty (TKA) with off-the-shelf TKA. In the patient-specific model, the femoral condyle curves were considered in the femoral component's inner and outer surface design. The tibial component was designed to completely cover the tibia cutting surface. In vitro experiments were conducted to compare these two models in terms of loosening of the components. A probabilistic approach based on the finite element method was also used to compute the probability of failure of both models. According to the deterministic analysis results, 103.10 and 21.67 MPa von Mises stress values were obtained for the femoral component and cement in the anatomical model, while these values were 175.86 and 25.76 MPa, respectively, for the conventional model. In order to predict loosening damage due to local osteolysis or stress shield, it was determined that the deformation values in the examined cement structures were 15% lower in the anatomical model. According to probabilistic analysis results, it was observed that the probability of encountering an extreme value for the anatomical model is far less than that of the conventional model. This indicates that the anatomical model is safer than the conventional model, considering the failure scenarios in this study.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"295-305"},"PeriodicalIF":1.7,"publicationDate":"2022-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40121668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smart piezoelectric biomaterials for tissue engineering and regenerative medicine: a review. 用于组织工程和再生医学的智能压电生物材料综述。

IF 1.7

Biomedizinische Technik. Biomedical engineering Pub Date : 2022-03-22 Print Date: 2022-04-26 DOI: 10.1515/bmt-2021-0265

Aryan Najjari, Rouhollah Mehdinavaz Aghdam, S A Seyyed Ebrahimi, Shoma Suresh K, Sasirekha Krishnan, Chittibabu Shanthi, Murugan Ramalingam

{"title":"Smart piezoelectric biomaterials for tissue engineering and regenerative medicine: a review.","authors":"Aryan Najjari, Rouhollah Mehdinavaz Aghdam, S A Seyyed Ebrahimi, Shoma Suresh K, Sasirekha Krishnan, Chittibabu Shanthi, Murugan Ramalingam","doi":"10.1515/bmt-2021-0265","DOIUrl":"https://doi.org/10.1515/bmt-2021-0265","url":null,"abstract":"Due to the presence of electric fields and piezoelectricity in various living tissues, piezoelectric materials have been incorporated into biomedical applications especially for tissue regeneration. The piezoelectric scaffolds can perfectly mimic the environment of natural tissues. The ability of scaffolds which have been made from piezoelectric materials in promoting cell proliferation and regeneration of damaged tissues has encouraged researchers in biomedical areas to work on various piezoelectric materials for fabricating tissue engineering scaffolds. In this review article, the way that cells of different tissues like cardio, bone, cartilage, bladder, nerve, skin, tendon, and ligament respond to electric fields and the mechanism of tissue regeneration with the help of piezoelectric effect will be discussed. Furthermore, all of the piezoelectric materials are not suitable for biomedical applications even if they have high piezoelectricity since other properties such as biocompatibility are vital. Seen in this light, the proper piezoelectric materials which are approved for biomedical applications are mentioned. Totally, the present review introduces the recent materials and technologies that have been used for tissue engineering besides the role of electric fields in living tissues.","PeriodicalId":93905,"journal":{"name":"Biomedizinische Technik. Biomedical engineering","volume":" ","pages":"71-88"},"PeriodicalIF":1.7,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40311281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8