Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia最新文献

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Safety of Custodiol for Myocardial Protection in Minimally Invasive Mitral Valve Repair: A Japanese Single-Center Retrospective Comparison with Blood Cardioplegia in Conventional Sternotomy Repair. 在微创二尖瓣修复中,库地醇对心肌保护的安全性:一项日本单中心回顾性比较与传统胸骨切开修复中血液停搏的比较。
IF 1.3
Hiroaki Aizawa, Akihiro Yoshitake, Yuki Katsunori, Osamu Kinoshita, Yu Kumagai, Taro Kuroda, Yuta Kanazawa, Yuko Gatate, Takayuki Gyoten, Toshihisa Asakura
{"title":"Safety of Custodiol for Myocardial Protection in Minimally Invasive Mitral Valve Repair: A Japanese Single-Center Retrospective Comparison with Blood Cardioplegia in Conventional Sternotomy Repair.","authors":"Hiroaki Aizawa, Akihiro Yoshitake, Yuki Katsunori, Osamu Kinoshita, Yu Kumagai, Taro Kuroda, Yuta Kanazawa, Yuko Gatate, Takayuki Gyoten, Toshihisa Asakura","doi":"10.5761/atcs.oa.25-00208","DOIUrl":"10.5761/atcs.oa.25-00208","url":null,"abstract":"<p><strong>Purpose: </strong>Research regarding Custodiol's safety in minimally invasive mitral valve repair remains limited in Asian populations. We compared Custodiol in minimally invasive mitral valve repair to repetitive cold blood cardioplegia in open mitral valve repair.</p><p><strong>Methods: </strong>We retrospectively evaluated 98 consecutive patients who underwent minimally invasive mitral valve repair with Custodiol and 70 consecutive patients who underwent open mitral valve repair with repetitive cold blood cardioplegia at our institution between January 2015 and December 2024. The primary endpoints were creatine kinase-myocardial band (MB) levels and left ventricular ejection fraction determined by echocardiography pre- and post-surgery.</p><p><strong>Results: </strong>Maximum creatine kinase-MB levels within 48 h post-surgery were significantly lower in the minimally invasive group than in the open repair group, both in the overall cohort (45.0 vs. 60.7 U/L; p <0.001, respectively) and after excluding patients who underwent Maze procedure or pulmonary vein isolation (42.4 vs. 50.0 U/L; p = 0.009, respectively). Left ventricular ejection fraction pre- and post-surgery was comparable between the minimally invasive and open repair groups (72% vs. 69%; p = 0.426 and 59% vs. 60%; p = 0.204, respectively).</p><p><strong>Conclusion: </strong>Custodiol during minimally invasive mitral valve repair provides myocardial protection comparable to repetitive cold blood cardioplegia in open mitral valve repair.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12950296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147277606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative Low Serum Basophil Levels Predict Poor Prognosis for the Patients with Esophageal Squamous Cell Carcinoma. 术前低血清嗜碱性粒细胞水平预测食管鳞状细胞癌患者预后不良。
IF 1.3
Fumiaki Shiratori, Satoshi Yajima, Takashi Suzuki, Yoko Oshima, Teruki Yamakawa, Yuichiro Ohtsuka, Hideaki Shimada
{"title":"Preoperative Low Serum Basophil Levels Predict Poor Prognosis for the Patients with Esophageal Squamous Cell Carcinoma.","authors":"Fumiaki Shiratori, Satoshi Yajima, Takashi Suzuki, Yoko Oshima, Teruki Yamakawa, Yuichiro Ohtsuka, Hideaki Shimada","doi":"10.5761/atcs.oa.26-00001","DOIUrl":"10.5761/atcs.oa.26-00001","url":null,"abstract":"<p><strong>Purpose: </strong>A decrease in peripheral basophil count has recently been suggested as a potential marker of poor prognosis in malignancies. This study aimed to determine the optimal cutoff value for basophil count and assess its clinicopathological and prognostic significance in esophageal squamous cell carcinoma (ESCC).</p><p><strong>Methods: </strong>We retrospectively analyzed 194 patients with ESCC (157 men, 37 women; mean age, 67 years [range, 34-88]) who underwent curative surgery between 2010 and 2020, including 100 who received neoadjuvant chemotherapy. Receiver-operating characteristic curve analysis identified an optimal basophil cutoff value of 17.4/μL. Patients were divided into low- and high-basophil groups, and clinicopathological factors and prognosis were assessed using univariate and multivariate analyses.</p><p><strong>Results: </strong>Low-basophil counts were significantly correlated with low neutrophil counts but not with C-reactive protein level. Multivariate analysis to predict overall survival identified deep invasion, elevated C-reactive protein, and low-basophil count as independent predictors of a poor prognosis (P <0.05).</p><p><strong>Conclusion: </strong>Low preoperative basophil count is an independent adverse prognostic factor in ESCC. As basophil count was not correlated with C-reactive protein, it may provide prognostic value beyond conventional inflammation-based markers and could represent a simple, low-cost biomarker to aid risk stratification in the preoperative setting.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12967339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Management of Primary and Metastatic Cardiac Malignancies: A 20-Year Single-Center Experience. 原发性和转移性心脏恶性肿瘤的外科治疗:20年的单中心经验。
IF 1.3
Ryo Nakanishi, Hiroto Kawakami, Naoto Tanabe, Koki Tamaoka, Akira Takeuchi, Shoichi Kyo, Tomofumi Taki, Hiroshi Tsuneyoshi
{"title":"Surgical Management of Primary and Metastatic Cardiac Malignancies: A 20-Year Single-Center Experience.","authors":"Ryo Nakanishi, Hiroto Kawakami, Naoto Tanabe, Koki Tamaoka, Akira Takeuchi, Shoichi Kyo, Tomofumi Taki, Hiroshi Tsuneyoshi","doi":"10.5761/atcs.oa.26-00025","DOIUrl":"10.5761/atcs.oa.26-00025","url":null,"abstract":"<p><strong>Purpose: </strong>Malignant cardiac tumors are rare and have a poor prognosis. Surgical resection is performed for symptom relief and survival benefit, but its efficacy is limited. We reviewed our 20-year single-institution experience with primary and metastatic malignant cardiac tumors.</p><p><strong>Methods: </strong>We retrospectively reviewed 15 patients who underwent resection for histologically confirmed malignant cardiac tumors between 2006 and 2025. Data included tumor characteristics, resection status, and survival outcomes.</p><p><strong>Results: </strong>Of 15 patients, 7 (46.7%) had primary tumors (most common: angiosarcoma) and 8 (53.3%) had metastatic lesions. The right atrium was the most frequent site (60.0%). Complete (R0) resection was achieved in only 3 cases (20.0%). Median overall survival (OS) for the cohort was 11 months. Patients with angiosarcoma had particularly poor outcomes (median OS: 5 months). One patient with metastatic thymic carcinoma achieved long-term survival (>15 years) following multimodal therapy. Adjuvant therapy was administered in 7 patients (46.7%). No 30-day postoperative mortality occurred.</p><p><strong>Conclusion: </strong>Surgical resection of malignant cardiac tumors is feasible with acceptable perioperative safety. Although R0 resection is rarely attainable and long-term outcomes remain poor, particularly for high-grade sarcomas, a multimodal approach is essential to optimize outcomes in selected patients.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13092346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Left Atrial Hemodynamics on the Development of Pulmonary Vein Stump Thrombus: Results of Early and Late Postoperative Studies. 左房血流动力学对肺静脉残端血栓形成的影响:术后早期和晚期研究结果
IF 1.3
Tadashi Umehara, Takuya Tokunaga, Koji Takumi, Go Kamimura, Masaya Aoki, Kazuhiro Ueda
{"title":"Impact of Left Atrial Hemodynamics on the Development of Pulmonary Vein Stump Thrombus: Results of Early and Late Postoperative Studies.","authors":"Tadashi Umehara, Takuya Tokunaga, Koji Takumi, Go Kamimura, Masaya Aoki, Kazuhiro Ueda","doi":"10.5761/atcs.oa.25-00099","DOIUrl":"10.5761/atcs.oa.25-00099","url":null,"abstract":"<p><strong>Purpose: </strong>Pulmonary vein stump thrombus (PVST) is a relatively common complication after left upper lobectomy that can cause vital organ embolism. We previously found that patients with PVST on postoperative day 7 show risky hemodynamic features around the pulmonary vein stump on 4-dimensional (4D) flow magnetic resonance imaging (MRI), which may contribute to thrombus development. However, it remains unclear whether such hemodynamics persist later.</p><p><strong>Methods: </strong>Eleven patients who underwent left upper lobectomy for lung cancer received 4D flow MRI on postoperative day 7 and again after over 3 months. Hemodynamic parameters were used to classify each case as risky or non-risky for PVST.</p><p><strong>Results: </strong>According to a total of 24 examinations in 11 patients, 7 were classified as risky and 17 as non-risky. PVST developed in 6 patients during various postoperative phases, and all PVST cases developed under the risky conditions. Furthermore, PVST did not develop under non-risky conditions, suggesting that our risk assessment is valid as a predictive marker for PVST.</p><p><strong>Conclusion: </strong>Our results suggest that late postoperative hemodynamic assessments, as well as early postoperative assessments, are useful for identifying patients at high risk of PVST. A late postoperative hemodynamic assessment may contribute to determining when to discontinue anticoagulants.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12795627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CT-Derived Aortic Plaque Characteristics Predict MRI-Detected Silent Cerebral Infarction after Total Aortic Arch Replacement. ct来源的主动脉斑块特征预测全主动脉弓置换术后mri检测的无症状脑梗死。
IF 1.3
Fumio Yamana, Kazuo Shimamura, Takayuki Shijo, Koichi Maeda, Kizuku Yamashita, Ryoto Sakaniwa, Shigeru Miyagawa
{"title":"CT-Derived Aortic Plaque Characteristics Predict MRI-Detected Silent Cerebral Infarction after Total Aortic Arch Replacement.","authors":"Fumio Yamana, Kazuo Shimamura, Takayuki Shijo, Koichi Maeda, Kizuku Yamashita, Ryoto Sakaniwa, Shigeru Miyagawa","doi":"10.5761/atcs.oa.25-00215","DOIUrl":"10.5761/atcs.oa.25-00215","url":null,"abstract":"<p><strong>Purpose: </strong>Silent cerebral infarctions are common after aortic arch surgery; however, the predictive value of preoperative computed tomography (CT)-derived plaque characteristics remains unclear. We investigated the incidence, distribution, and risk factors for new cerebral infarction lesions (NCILs) after total aortic arch replacement (TAR), focusing on low-attenuation plaque (LAP, 0-60 Hounsfield units [HU], a surrogate of lipid-rich vulnerable plaque) burden.</p><p><strong>Methods: </strong>Among 82 consecutive TAR patients, 41 underwent both pre- and postoperative brain diffusion-weighted magnetic resonance imaging (MRI). Clinical profiles, CT-derived atheroma grade and plaque attenuation, operative details, and outcomes were compared between NCIL-positive and NCIL-negative groups. The primary multivariable model simultaneously included arch atheroma grade and LAP area, adjusted for age and sex.</p><p><strong>Results: </strong>NCILs were detected in 25/41 patients (61%): 23 silent and 2 symptomatic. All NCILs exhibited embolic imaging features without watershed or hypoperfusion patterns. NCIL-positive patients had significantly greater arch LAP area (63.9 vs. 17.7 mm<sup>2</sup>, p <0.01). On multivariable analysis, arch LAP remained the only independent predictor (OR per 10 mm<sup>2</sup>, 3.01; 95% confidence interval [CI] 1.50-8.75; p = 0.012), whereas atheroma grade was not.</p><p><strong>Conclusion: </strong>More than half of TAR patients developed MRI-detected, predominantly silent NCILs. Preoperative arch LAP was the sole independent predictor. LAP assessment may refine intraoperative risk stratification and guide tailored neuroprotective strategies.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13082872/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pericardial Closure Using Donor Pericardium in Deceased-Donor Lung Transplantation. 用供体心包闭合在死亡供体肺移植中的应用。
IF 1.3
Taiki Ryo, Akihiro Ohsumi, Ichiro Sakanoue, Hidenao Kayawake, Satona Tanaka, Yojiro Yutaka, Daisuke Nakajima, Hiroshi Date
{"title":"Pericardial Closure Using Donor Pericardium in Deceased-Donor Lung Transplantation.","authors":"Taiki Ryo, Akihiro Ohsumi, Ichiro Sakanoue, Hidenao Kayawake, Satona Tanaka, Yojiro Yutaka, Daisuke Nakajima, Hiroshi Date","doi":"10.5761/atcs.oa.26-00023","DOIUrl":"https://doi.org/10.5761/atcs.oa.26-00023","url":null,"abstract":"<p><strong>Purpose: </strong>The optimal method of pericardial closure in lung transplantation remains controversial. This study aimed to evaluate the technical feasibility and procedural simplicity of pericardial closure using donor pericardium.</p><p><strong>Methods: </strong>We retrospectively reviewed 70 adult patients who underwent deceased-donor bilateral lung transplantation with cardiopulmonary bypass or central extracorporeal membrane oxygenation between December 2010 and January 2024 at Kyoto University Hospital. Patients were divided into the Donor pericardium group (n = 21) and the Autologous tissue group (n = 49). Pericardial closure time was assessed as an indicator of procedural simplicity, and postoperative complications within 1 year were descriptively evaluated.</p><p><strong>Results: </strong>Baseline characteristics did not differ between the groups. Mean pericardial closure time was significantly shorter in the Donor pericardium group than in the Autologous tissue group (13 ± 2.4 vs 19 ± 1.6 min, P = 0.03). No clinically concerning differences in postoperative complications were observed during short- to mid-term follow-up.</p><p><strong>Conclusion: </strong>Pericardial closure using donor pericardium enables technically simpler and faster closure without apparent short-term safety concerns.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147792127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal Aortoesophageal Fistula after Esophagectomy for Esophageal Cancer: A Single-Center Retrospective Analysis. 食管癌食管切除术后致死性主动脉食管瘘:单中心回顾性分析。
IF 1.3
Lianzheng Zhao, Zhen Zhang, Huijiang Gao, Guodong Shi, Jiangshan Ai, Yucheng Wei
{"title":"Fatal Aortoesophageal Fistula after Esophagectomy for Esophageal Cancer: A Single-Center Retrospective Analysis.","authors":"Lianzheng Zhao, Zhen Zhang, Huijiang Gao, Guodong Shi, Jiangshan Ai, Yucheng Wei","doi":"10.5761/atcs.oa.26-00037","DOIUrl":"https://doi.org/10.5761/atcs.oa.26-00037","url":null,"abstract":"<p><strong>Purpose: </strong>Aortoesophageal fistula (AEF) after esophagectomy is a rare but catastrophic complication, often occurring after anastomotic leakage and mediastinal contamination. Evidence regarding fatal trajectories and rescue failure points remains limited.</p><p><strong>Methods: </strong>We performed a retrospective, single-center study among esophageal cancer patients who developed AEF after esophagectomy between 2013 and 2024. Cases were identified from institutional databases and mortality records, followed by manual screening. Clinical course, antecedent complications, diagnostic workup, rescue interventions, and causes of death were summarized descriptively.</p><p><strong>Results: </strong>Among 5543 esophagectomies, 17 patients (0.31%) developed AEF: 16 fatal (94.1%) and 1 survivor (5.9%). All were male, median age 63 years. Anastomotic leak occurred in 16 patients (94.1%), all with mediastinal infection. Sentinel bleeding preceded hemorrhage in 14 patients (82.4%); the median interval to fatal hemorrhage was 1 day.</p><p><strong>Conclusions: </strong>Post-esophagectomy AEF is highly lethal. Sentinel bleeding represents a critical intervention window. Prompt recognition and multidisciplinary escalation may enable survival even in high-risk patients.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13110882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147792135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Outcomes of Central Airway Adenoid Cystic Carcinoma: A Retrospective Single-Center Analysis. 中央气道腺样囊性癌的手术结果:回顾性单中心分析。
IF 1.3
Toshihiko Soma, Shinjiro Nagai, Takashi Indo, Satoshi Ueda, Naoko Imanishi, Mitsuhiro Ueda, Yoshihiro Miyamoto
{"title":"Surgical Outcomes of Central Airway Adenoid Cystic Carcinoma: A Retrospective Single-Center Analysis.","authors":"Toshihiko Soma, Shinjiro Nagai, Takashi Indo, Satoshi Ueda, Naoko Imanishi, Mitsuhiro Ueda, Yoshihiro Miyamoto","doi":"10.5761/atcs.oa.25-00210","DOIUrl":"10.5761/atcs.oa.25-00210","url":null,"abstract":"<p><strong>Purpose: </strong>Central airway adenoid cystic carcinoma (CAACC) is a rare malignancy lacking a standard treatment approach and often precluding complete resection. This study assessed the surgical outcomes of patients with CAACC treated at a single institution.</p><p><strong>Methods: </strong>We retrospectively reviewed patients who underwent surgical resection for CAACC between September 2013 and August 2021.</p><p><strong>Results: </strong>Eight patients (mean age: 51.5 years) were included. Tumor locations were bronchus (n = 1), trachea (n = 4), carina and bronchus (n = 2), and carina and trachea (n = 1). Surgical procedures included sleeve lobectomy (n = 1), tracheal resection (n = 4), sleeve pneumonectomy (n = 2), and carinal resection with reconstruction (n = 1). Preoperative radiation and bronchoscopic tumor resection were performed in 1 patient each. One patient died from a postoperative tracheoinnominate artery fistula. Major complications included recurrent laryngeal nerve palsy (n = 3). Adjuvant therapy was provided for positive or uncertain margins. During a median follow-up of 6 years, 2 patients developed recurrence but remained alive at the last follow-up. The 5-year overall survival rate was 72.9%.</p><p><strong>Conclusion: </strong>Surgical resection with airway reconstruction and adjuvant therapy can offer long-term disease control in CAACC, though life-threatening complications warrant careful consideration.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12928833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146222449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Bilateral and Single Internal Thoracic Artery Bypass Grafting on Postoperative Reverse Remodeling in Patients with End-Stage Ischemic Cardiomyopathy. 双侧和单侧胸内动脉旁路移植术对终末期缺血性心肌病患者术后逆转重构的影响。
IF 1.3
Yusuke Misumi, Daisuke Yoshioka, Takuji Kawamura, Ai Kawamura, Shin Yajima, Shunsuke Saito, Takashi Yamauchi, Kazuo Shimamura, Shigeru Miyagawa
{"title":"Impact of Bilateral and Single Internal Thoracic Artery Bypass Grafting on Postoperative Reverse Remodeling in Patients with End-Stage Ischemic Cardiomyopathy.","authors":"Yusuke Misumi, Daisuke Yoshioka, Takuji Kawamura, Ai Kawamura, Shin Yajima, Shunsuke Saito, Takashi Yamauchi, Kazuo Shimamura, Shigeru Miyagawa","doi":"10.5761/atcs.oa.25-00189","DOIUrl":"10.5761/atcs.oa.25-00189","url":null,"abstract":"<p><strong>Purpose: </strong>The internal thoracic artery (ITA) has shown increased production of nitric oxide, which has beneficial effects on ventricular remodeling, among conduits of coronary artery bypass grafting (CABG). However, little is known about the impact of bilateral ITA strategy on postoperative left ventricle (LV) reverse remodeling as compared with single ITA, especially in patients with severely impaired LV function.</p><p><strong>Methods: </strong>We retrospectively reviewed 126 propensity-matched patients with advanced ischemic cardiomyopathy (ICM) (left ventricular ejection fraction <40%) who underwent isolated multiple CABG utilizing bilateral (BITA group; n = 65) or single (SITA group; n = 61) ITA. The primary endpoint was postoperative reduction in the indexed left ventricular end-systolic volume index (LVESVI). Baseline covariates were adjusted with propensity score-matching.</p><p><strong>Results: </strong>At baseline, there were no intergroup differences in LVESVI (78 vs. 78 ml/m<sup>2</sup>, P = 0.93) and EuroSCORE II score (3.0% vs. 2.8%, P = 0.70). At 6 months post-surgery, the BITA group reduced LVESVI to a greater degree than the SITA group (-33% vs. -17%, P <0.01), resulting in significantly smaller postoperative LVESVI (49 vs. 63 ml/m<sup>2</sup>, P = 0.03). Multivariable analysis showed that CABG with BITA (P = 0.011) was associated with postoperative LV reverse remodeling.</p><p><strong>Conclusion: </strong>In patients with ICM undergoing CABG, the in situ BITA strategy was associated with greater reductions in postoperative LV volume.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12812433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145986001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical Outcomes and Prognostic Impact of Lung Cancer Associated with Cystic Airspaces: A Retrospective Analysis of 75 Cases. 伴有囊性气隙的肺癌的手术结果和预后影响:75例回顾性分析
IF 1.3
Yuichiro Machida, Kento Suzuki, Mitsunobu Ino, Takumi Sonokawa, Norihito Kawasaki, Jitsuo Usuda
{"title":"Surgical Outcomes and Prognostic Impact of Lung Cancer Associated with Cystic Airspaces: A Retrospective Analysis of 75 Cases.","authors":"Yuichiro Machida, Kento Suzuki, Mitsunobu Ino, Takumi Sonokawa, Norihito Kawasaki, Jitsuo Usuda","doi":"10.5761/atcs.oa.25-00070","DOIUrl":"10.5761/atcs.oa.25-00070","url":null,"abstract":"<p><strong>Purpose: </strong>The present study reviewed surgical cases of lung cancer associated with cystic airspace (LCCA) and examined the imaging and clinicopathological features of these cases.</p><p><strong>Methods: </strong>A total of 75 patients with lung cancer associated with cystic airspace, who underwent lung cancer surgery in our hospital between January 2017 and December 2020, were included. We retrospectively analyzed the association between postoperative recurrence of lung cancer and lung cancer associated with the cystic airspace using the Cox proportional hazards model.</p><p><strong>Results: </strong>Patients with LCCA had a worse prognosis than those with non-LCCA. Furthermore, a univariate analysis showed a significant difference between sex, smoking, differentiation, tumor size, Stage, and LCCA, while a multivariate analysis showed a significant difference between Stage and LCCA. LCCA cases were classified into four categories, as reported in a previous study. Types I and III showed more adenocarcinomas, while Type IV tended to show squamous cell carcinomas.</p><p><strong>Conclusions: </strong>LCCA has a poor prognosis. It is often difficult to determine which of the T factors of the TNM classification are applied. Therefore, further studies are needed to accumulate more LCCA cases.</p>","PeriodicalId":93877,"journal":{"name":"Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia","volume":"32 1","pages":""},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12989256/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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