日本老年腹主动脉瘤患者择期血管内动脉瘤修复术的远期疗效。

Toshiya Nishibe, Masaki Kano, Shinobu Akiyama, Toru Iwahashi, Shoji Fukuda
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引用次数: 0

摘要

目的:我们主要关注高龄腹主动脉瘤腔内修复(EVAR)患者过度治疗的风险。我们调查了日本老龄化人口中EVAR发生时的年龄与全因死亡率之间的关系,将患者分为不同的年龄组。方法:分析2012 - 2016年175例选择性EVAR患者的资料。结果:175例患者中,老年患者3年和5年生存率明显较低,75 ~ 84岁患者3年和5年生存率分别为74.6%和64.2%,≥85岁患者3年和5年生存率分别为51.9%和39.7%。多因素分析发现,年龄≥85岁、慢性肾脏疾病、慢性阻塞性肺病和活动性癌症是全因死亡率的独立不利预测因素,而肥胖被确定为独立的保护性预测因素。结论:调整指南,不仅考虑合并症,而且考虑年龄因素,通过优先考虑最有可能受益于日本超老龄化社会的患者的EVAR,可以优化结果和医疗资源配置。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-Term Outcomes of Elective Endovascular Aneurysm Repair for Abdominal Aortic Aneurysm in Japanese Elderly Patients.

Purpose: Our primary concern was the risk of overtreating elderly patients with endovascular aneurysm repair (EVAR) for abdominal aortic aneurysm. We investigated the association between age at the time of EVAR and all-cause mortality in Japan's aging population by stratifying patients into age groups.

Methods: Data from 175 patients who underwent elective EVAR from 2012 to 2016 were analyzed. Patients were categorized into 3 age groups: <75 years, 75-84 years, and ≥85 years, based on Japan's healthy life expectancy and average life expectancy. Survival rates and risk factors for mortality were assessed across these patient groups.

Results: Among 175 patients, 3- and 5-year survival rates were significantly lower in elderly patients, with rates of 74.6% and 64.2% for those aged 75-84 years and 51.9% and 39.7% for those aged ≥85 years. Multivariate analysis identified age ≥85 years, chronic kidney disease, chronic obstructive pulmonary disease, and active cancer as independent adverse predictors of all-cause mortality, whereas obesity was identified as an independent protective predictor.

Conclusions: Adjusting guidelines to incorporate not only comorbidities but also age could optimize outcomes and healthcare resource allocation by prioritizing EVAR for patients most likely to benefit in Japan's super-aging society.

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