{"title":"Risk Factors for Death of Burn Patients With Acute Respiratory Distress Syndrome.","authors":"T D Hung, N N Lam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study was to investigate factors independently affecting outcomes of post-burn ARDS patients at the time of ARDS onset. A prospective study was conducted on 66 patients with ARDS, treated in the ICU at the Le Huu Trac National Burns Hospital in Hanoi, Viet Nam, from 2014 to 2017. Patients were divided into a survivor and non-survivor group. Demographic criteria, burn severity, inhalation injury, clinical and subclinical features at ARDS onset were compared between the two groups. The results showed that overall mortality of ARDS patients was 62.12%. Logistic regression analysis indicated that at the time of ARDS onset, serum lactate level (OR=6.71), blood platelet count (OR=.99), static lung compliance (OR=.73) and driving pressure (OR=1.69) were independent risk factors for death, while patients' demographics, burn severity and ARDS severity did not significantly affect the mortality rate.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 4","pages":"271-275"},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Fredj, D Tarchella, A Mokline, M Ben Saad, B Gasri, I Jami, A A Messadi
{"title":"Suicide by Self-Immolation in the Pediatric Population.","authors":"H Fredj, D Tarchella, A Mokline, M Ben Saad, B Gasri, I Jami, A A Messadi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Self-immolation is a violent way of committing suicide. Few studies have focused on this phenomenon in children. The aim of this study was to determine the epidemiological profile of children who committed suicide by fire. A retrospective descriptive study was conducted in an intensive burn care department in Tunis, over a period of 10 years (2011-2020). Of a total 3077 patients, 761 were admitted for burns by suicide attempt, among them 62 children and adolescents (8%). The number was on average six per year. The highest annual prevalence was noted in 2011 (27% of cases). The mean age was 16 and a half years old. The majority of cases were adolescents aged 15 or older. There is a male predominance (sex ratio:3). Total burn surface area (TBSA) was on average 44%. The act of self-immolation occurred in public places in 58% of cases. Socio-economic environment was unfavorable in 60% of cases. The suicidal act of self-immolation was due to a family conflict in 34% of cases (n=21). Seven patients (11%) had a history of mental illness. Forty-three patients (70%) required mechanical ventilation. The length of hospital stay was on average 30 days. The mortality rate was 56.5%. In conclusion, self-immolation is frequent in the pediatric population; it induces severe burns associated with a poor prognosis.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 4","pages":"307-312"},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Epidemiology of Burned Inpatient Children in French Guyana].","authors":"N Martz, A Sika, P Guemaleu, N Elenga, F Quet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This descriptive observational study aims to describe the epidemiological profile of children hospitalized for burns in Guyana, a French district which does not have a burn treatment centre, and direct prevention towards the populations most at risk. Retrospective analysis of 665 hospitalizations was made thanks to the coding of patients aged 0 to 18, hospitalized for burns between January 2010 and December 2022 at Cayenne Hospital Centre. Univariate and multivariate descriptive analyses were carried out on age, sex, municipality of origin, date of burn, duration of hospitalization, mode of burn, location, percentage and depth of burn. A total 416 children with \"burn\" coding were hospitalized over this period and 358 patients were included. Burns were more common in males (58%) and in children under 6 (75%). A majority of patients were townspeople and lived on the coast (70%). 9.5% of patients were transferred to Trousseau Hospital in Paris for more specialized care. 61% of burns were caused by hot water and 16.5% by flames. Duration of hospitalization was on average 8 days and the burnt skin surface was 9.5%. Children under 2 years old living in Cayenne and its suburbs are the most at risk of burns, but the most serious burns requiring a transfer to Paris are found in children over 3 years old living on the Maroni River and playing with flammable products.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 4","pages":"293-298"},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Description of Aspartate Aminotransferase and Alanine Aminotransferase in Burn Patients at the Burn Unit of Dr. Hasan Sadikin General Hospital (Rshs) Bandung.","authors":"H Soedjana, A C Putri, M Arsyad, N Andalu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Burn injury is trauma with several metabolic reactions including hepatocytes that can cause apoptosis and necrosis. Proliferation occurs to compensate for this reaction but complicates with the loss of protein of the injury. The aim of this study is to describe the level of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in burn injury. This study was a descriptive retrospective design using secondary data from medical records of patients at the Burns Unit of Dr. Hasan Sadikin Hospital Bandung (RSHS) in the period August 2017 to July 2019. Total samples in this study were 116 people. Normal level of AST and ALT was found in 23 people (19.8%), elevation of AST in 31 people (26.7%), elevation of ALT in 5 people (4.3%) and elevation of both AST and ALT in 57 people (41.3%). Increased levels of AST and ALT mostly occurred in men (51%), aged 45 years (56%), with injury due to electricity (26%), 20-29% burn area (32%), and occurred in the first week of wound onset. Most cases of burn injury showed increasing levels of AST and ALT. This might be due to the metabolism of hepatocytes in burn cases. Elevation of AST and ALT was mainly found in burn injury cases at RSHS notably in the first week of onset. Further research is needed to verify the relation of this condition. Elevated levels of AST and ALT should be the consideration of clinicians in giving therapy.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 3","pages":"217-221"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P K Dey, A Galib, A Sardar, M T Islam, H M Z Sharif, F Zaman, N Hannan, M A Rafi
{"title":"Nosocomial Infection Among Burn Patients Admitted to a Tertiary Care Hospital of Bangladesh: A Cross-Sectional Study.","authors":"P K Dey, A Galib, A Sardar, M T Islam, H M Z Sharif, F Zaman, N Hannan, M A Rafi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nosocomial infection is a major challenge for the appropriate management of burns. The present study aimed to investigate incidence, risk factors, and causative organisms of nosocomial infection in burn patients of Khulna, Bangladesh. This cross-sectional study was conducted among patients admitted to the Burn and Plastic Surgery Department of Khulna Medical College Hospital (KMCH) from January to December 2020. Relevant data were collected from the patients' hospital records. Samples of wound swabs and blood were collected and cultured in the microbiology laboratory of KMCH. Logistic regression models were used to determine risk factors for infective complications in burn patients. All statistical analyses were carried out using SPSS version 26.0. A total of 100 burn patients were included. Mean age was 29.2 years with a male-female ratio of 1.3:1. Flame burns were most prevalent among the patients (41%), followed by scald (23%) and electric burns (15%). Almost 40% patients had full thickness burn. The incidence of nosocomial infection was 42% (wound infection 33% and septicemia 9%). Total body surface area of burn >40% (OR 7.56, 95% CI 2.89-19.81), full thickness burn (OR 34.40, 95% CI 3.25-97.14) and prolonged hospital stay (aOR 1.31, 95% CI 1.15-1.51) were significant risk factors for nosocomial infection. <i>Staphylococcus aureus</i> was the most commonly isolated organism (45%), followed by <i>Streptococcus</i> (24%), <i>Pseudomonas aeruginosa</i> (19%) and <i>Escherichia coli</i> (12%). As the epidemiology of nosocomial infection is not the same in different health facilities, a facility-based comprehensive burn management protocol considering the local epidemiology and causative organisms of burn wound infection is crucial for the prevention and management of nosocomial infections in burn patients.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 3","pages":"202-208"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140868774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cost Analysis and Influencing Factors Amongst Severe Burn Patients.","authors":"N N Lam, N T Hung, N N Khanh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study analyzed the structure and determined the factors affecting the cost of treatment of severe burns patients. The results showed that the average total costs for a patient was 3275.9 USD. The daily cost of hospitalization was 113.3 USD, the treatment cost for 1% burn surface area was 109.5 USD with the highest proportion for medication and consumable medical equipment (43.2%), followed by surgery and procedures (30.2%). The treatment costs increased with increasing age, burn extent and deep burn area (p < .05) and were significantly higher in the group of patients with inhalation injury, electrical burns and in non-survivors (p < .01). Multivariate regression analysis found that burn extent, deep burn area and inhalation injury independently influenced the treatment cost of burn patients.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 3","pages":"183-188"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M R Seswandhana, I D Kurniawan, S L Anwar, H M A Humani, G C Gabriela, I Dachlan, Y W Wirohadidjojo, I Aryandono
{"title":"The Effects of Negative Pressure Wound Therapy on Vegf and Angiogenesis in Deep Dermal Burn Injury: An Experimental Study.","authors":"M R Seswandhana, I D Kurniawan, S L Anwar, H M A Humani, G C Gabriela, I Dachlan, Y W Wirohadidjojo, I Aryandono","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Burn injuries are the fourth most common type of trauma worldwide, after traffic injuries, falls and interpersonal violence. Vascular endothelial growth factor (VEGF) is one of the most critical proangiogenic factors. Failure in angiogenesis is often associated with chronic, non-healing wounds. This study aimed to compare the effect of sterile gauze with normal saline (NaCl) 0.9%, intermittent negative pressure wound therapy (NPWT), continuous NPWT, and silver sulfadiazine dressing on increasing VEGF and angiogenesis in deep dermal burn injury. This experimental laboratory study involved six Yorkshire pigs. Twenty burns were made on each pig's flank and dorsum areas, which were divided into four treatment groups: sterile gauze with NaCl 0.9%, intermittent NPWT, continuous NPWT, and silver sulfadiazine dressing. Skin biopsies were done on days 1, 3, 7, 14 and 21 to evaluate VEGF histoscore and mean microvascular density (MVD). We used immunohistochemical staining of VEGF-165 as VEGF's protein marker and hematoxylin-eosin (HE) to count the MVD. There was a significant difference in mean VEGF histoscore on evaluation day 14, in which continuous NPWT had the highest score compared to sterile gauze with NaCl 0.9%, intermittent NPWT, and silver sulfadiazine. The elevated VEGF histoscore could significantly increase the MVD.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 3","pages":"222-228"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041890/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Rehan, T Iqbal, M Sarwar, M S Khan, M H Tariq, Q Ain, U Waheed
{"title":"Pattern of Acute Adverse Transfusion Reactions in Patients With Burn Injuries: A Novel Initiative Towards Haemovigilance at the National Burn Centre of Pakistan.","authors":"M Rehan, T Iqbal, M Sarwar, M S Khan, M H Tariq, Q Ain, U Waheed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The transfusion of blood and blood components is a life-saving medical procedure, however, it is linked with adverse reactions to transfusions. Information about different types of adverse transfusion reactions (ATRs) will assist in their early identification and subsequent management, as well as in devising strategies to minimize the occurrence of adverse reactions related to blood component transfusion. The current study was therefore executed to analyze the pattern of ATRs in patients with burn injuries at a national burn center. This was a cross-sectional, prospective study involving an analysis of immediate ATRs from January 2020 to June 2021 (18 months). ATRs observed during the study period were documented and analyzed. During the study period, 2,220 units of blood and blood components were transfused to 1,075 burn patients (2.06 transfusions per patient). A total of 27 ATRs were recorded (1.21%). Allergic reactions were the commonest (55.55%) followed by febrile non-haemolytic transfusion reaction (37.03%). The mean volume of blood unit transfused, when the reactions were noted, was approximately 75 ml (range: 15-230 ml). The mean time at which transfusion reactions were noted was 17 min (range: 5-220 minutes). The ATRs were more common in patients with multiple transfusions compared to those receiving a single transfusion. The common adverse reactions were allergic and febrile non-haemolytic transfusion reactions. It is vital to report all transfusion reactions to the attached blood center and hospital transfusion committee (HTC) on standardized reporting forms. Continuous medical education through seminars and sensitization workshops will support consolidating haemovigilance systems.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 3","pages":"261-265"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11042048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Ćertić, M Jovanović, M Karamarković, D Vasović, J Isaković-Subotić, M Živković, D Rašić
{"title":"The Impact of the COVID-19 Pandemic on Self-Inflicted Burn Injuries in Patients With Previously Diagnosed Bipolar Disorder.","authors":"B Ćertić, M Jovanović, M Karamarković, D Vasović, J Isaković-Subotić, M Živković, D Rašić","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Here we present a case of a 52-year-old female patient who was admitted to the Clinic in December 2021 due to the presence of right side facial burns which were caused by a cigarette lighter under suspicious conditions. Her past medical history revealed she was diagnosed with bipolar disorder at the age of 20 and was hospitalized multiple times for the treatment of manic episodes. The last psychiatric hospitalization took place in October 2021. She had deep second-degree burns on the right side of the face, head and neck, with a total body surface area involvement of approximately 3%. On hospital day 18, she was found unresponsive, dyspnoic, with no palpable pulse and measurable tension. Electrocardiogram (ECG) monitoring revealed sinus bradycardia followed by cardiac asystole. After the first few minutes of cardiopulmonary resuscitation, heart and lung action was re-established. Due to the presence of ECG changes in the form of ST depression and negative T waves in V2-V6, D1 and aVL, also higher blood level of high sensitivity troponin T, she was urgently transported to the Coronary Unit where she was diagnosed with non-ST-elevation myocardial infarction. On hospital day 27, due to the presence of sub-febrile temperature and non-productive cough, she was tested for COVID-19 infection and transported to the COVID Hospital Batajnica. She was discharged with stable laboratory parameters and normal chest radiography 37 days following initial admission. Considering the great psychological impact related to the COVID-19 pandemic, extensive mental health support and regular monitoring of critical groups is indicated.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 3","pages":"214-216"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J L Lisiecki, M R Buta, S Taylor, M Tait, N Farina, J Levin, J Schulz, N Sangji, J Friedstat, M R Hemmila, S Wang, B Levi, J Goverman
{"title":"Efficacy of Mepliex<sup>®</sup> Ag Versus Xeroform<sup>®</sup> As A Split-Thickness Skin Graft Donor Site Dressing: Bad Habits Die Hard.","authors":"J L Lisiecki, M R Buta, S Taylor, M Tait, N Farina, J Levin, J Schulz, N Sangji, J Friedstat, M R Hemmila, S Wang, B Levi, J Goverman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autografting with split-thickness skin grafts (STSG) remains an essential procedure in burn and reconstructive surgery. The process of harvesting STSG, however, leaves behind a donor site, an exposed area of partial-thickness dermis left to heal by secondary intention. There has yet to be a consensus amongst surgeons regarding optimal management of the donor site. The ideal donor site dressing is one that allows for expeditious healing while minimizing pain and infection. Despite numerous studies demonstrating the superiority of moist wound healing, many surgeons continue to treat STSG donor sites dry, with petroleum-based gauze. In this study, two burn centers performed a retrospective review of burn patients whose STSG donor sites were treated with either Xeroform<sup>®</sup> or Mepilex<sup>®</sup> Ag dressings. Infections were documented and in a subgroup analysis of patients, postoperative pain scores were noted and total opiate usage during hospitalization was calculated. Analysis revealed an overall infection rate of 1.2% in the Mepilex<sup>®</sup> Ag group and 11.4% in the Xeroform<sup>®</sup> group (p<0.0001). Patients with Xeroform<sup>®</sup> donor site dressings had increased odds of donor site infection (OR=10.8, p=0.002). In subgroup analysis, there were no significant differences in maximum pain scores between Mepilex<sup>®</sup> Ag and Xeroform<sup>®</sup> groups, nor were there differences in opiate usage. STSG donor sites dressed with silver foam dressings have a lower rate of donor site infection relative to those dressed with petroleum-based gauze. Moist donor site dressings such as foam dressings (including Mepilex<sup>®</sup> Ag) should be the standard of care in STSG donor site wound care.</p>","PeriodicalId":93873,"journal":{"name":"Annals of burns and fire disasters","volume":"36 3","pages":"243-250"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11041881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}