Anales de pediatria最新文献

{"title":"Severe hypertransaminasaemia during the acute hepatitis of unknown origin alert of 2022","authors":"Ana Martín Costa ,&nbsp;Ignacio Ros Arnal ,&nbsp;Ruth García Romero ,&nbsp;Gerardo Rodríguez Martínez ,&nbsp;Beatriz García Rodríguez","doi":"10.1016/j.anpede.2024.11.007","DOIUrl":"10.1016/j.anpede.2024.11.007","url":null,"abstract":"<div><h3>Introduction</h3><div>The impact of acute severe hepatitis of unknown origin in children (SHIC) subject to a medical alert in 2022 medical alert is poorly understood.</div></div><div><h3>Materials and methods</h3><div>Observational study of the incidence, aetiology and clinical presentation of acute hypertransaminasaemia (HTRA) with laboratory values in the severe range (ALT and/or AST ≥ 500 U/L) in paediatric patients (age 0 to 16 years) in one health care zone from 2012 to 2022, comparing the periods of the SHIC alert and the SARS-CoV2 pandemic with previous years.</div></div><div><h3>Results</h3><div>The incidence of severe HTRA of any cause was 195.28 per 100 000 blood tests, with an incidence of 181.38 in the SHIC alert period and 166.09 during the SARS-CoV-2 pandemic, without statistically significant differences.</div><div>Hepatitis of unknown origin accounted for 7.42% of total cases and transaminase levels normalised in 126 days (SD, 99.4). During the SHIC alert period there was a nonsignificant trend towards a higher incidence, as occurred in 2012 and 2018. In this group of cases, there was a significant increase in the presence of fever, vomiting and upper respiratory symptoms and lower levels of albumin and alkaline phosphatase. One patient required a liver transplant.</div></div><div><h3>Conclusions</h3><div>In our setting, there was no significant increase in the incidence of severe HTRA of any aetiology or of unknown source during either the SHIC alert or the SARS-CoV2 pandemic. In the SHIC alert period, a clinical pattern emerged characterised by an increase in nonspecific infectious symptoms, so we cannot rule out a higher prevalence of an infectious agent different from the usual involved pathogens, but it did not cause a significant change in epidemiological trends.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 6","pages":"Pages 370-377"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neutrophil CD64 expression increases in infants aged less than 3 months with fever without source: pilot study in the paediatric emergency care setting","authors":"Valeria Antoñanzas Bernar ,&nbsp;Pilar Storch de Gracia-Calvo ,&nbsp;Inés Leoz Gordillo ,&nbsp;Ana Castillo Robleda ,&nbsp;Alberto García-Salido","doi":"10.1016/j.anpede.2024.08.006","DOIUrl":"10.1016/j.anpede.2024.08.006","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 6","pages":"Pages 416-418"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142514476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric endoscopy in Spain: current situation and recent developments","authors":"María Navalón Rubio ,&nbsp;Carmen Jovani Casano ,&nbsp;Marta Soria López ,&nbsp;Alfonso Rodríguez Herrera ,&nbsp;Miguel Ángel López Casado ,&nbsp;Víctor Manuel Navas-López ,&nbsp;Víctor Vila Miravet ,&nbsp;en representación del Grupo de trabajo de Endoscopia pediátrica de la Sociedad Española de Gastroenterología Hepatología y Nutrición Pediátrica (SEGHNP)","doi":"10.1016/j.anpede.2024.11.004","DOIUrl":"10.1016/j.anpede.2024.11.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Paediatric gastrointestinal endoscopy (pGIE) has advanced significantly over the last decade, with increased diagnostic and therapeutic applications.</div></div><div><h3>Objectives</h3><div>This study examines the current state of pGIE in Spain, changes in the field over 5 years, and the involvement of paediatric gastroenterologists (pGEs).</div></div><div><h3>Materials and methods</h3><div>A structured self-administered questionnaire was distributed by the Endoscopy Working Group of the Spanish Society of Paediatric Gastroenterology, Hepatology, and Nutrition (SEGHNP) through the REDCap platform. The questionnaire included questions concerning techniques, sedation, indications, and organizational barriers. We compared the results with data from 2015.</div></div><div><h3>Results</h3><div>Eighty-one of the 103 invited hospitals participated (66.4%). Paediatric gastroenterologists performed 71% of scheduled pGIEs and 24% of emergency pGIEs. Therapeutic endoscopies accounted for 72% of procedures, including foreign body removal (50%) and polypectomy (36%), and were performed by pGEs in 61% and 63% of cases, respectively. When it came to other procedures, pGEs performed 24% in the case of hydrostatic dilation, 20% in the case of variceal sclerotherapy and of haemoclip placement, and 18% in the case of endoscopic coagulation. None of the endoscopic ultrasound, endoscopic retrograde cholangiopancreatography or enteroscopy procedures were performed by pGEs. Sedation was administered by anaesthesiologists in 70% of cases. Compared to 2015, there was an increase in the scheduled endoscopies performed by pGEs (71% vs 54%), the performance of gastroscopies (&gt;180 per year in 61% vs 24%) and colonoscopies (60−120 per year in 31% vs 12%) and the use of picosulfate for colonoscopy preparation (44% vs 10%).</div></div><div><h3>Conclusions</h3><div>There has been a significant increase in the involvement of pGEs in pGIE in Spain, although of lesser magnitude in emergency and therapeutic endoscopy procedures.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 6","pages":"Pages 393-400"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolopathy with characteristic clinical triad: Sengers syndrome","authors":"Laura Naqui Xicota,&nbsp;Elisenda Cortès-Saladelafont,&nbsp;Elena Berrocal Acevedo,&nbsp;Andrea Ros Peña,&nbsp;Berta Brussosa Ventura,&nbsp;Roser Porta Ribera","doi":"10.1016/j.anpede.2024.11.001","DOIUrl":"10.1016/j.anpede.2024.11.001","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 6","pages":"Pages 415-416"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Childhood desmoplastic ganglioglioma in an infant, radiological aspects to know","authors":"Juan Ramón y Cajal Calvo ,&nbsp;Laura Pérez Abad ,&nbsp;Patricia Morte Coscolin","doi":"10.1016/j.anpede.2024.11.003","DOIUrl":"10.1016/j.anpede.2024.11.003","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 6","pages":"Pages 421-422"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of respiratory distress syndrome in moderate/late preterm neonates: A Delphi consensus","authors":"Segundo Rite Gracia ,&nbsp;Juan José Agüera Arenas ,&nbsp;Gemma Ginovart Galiana ,&nbsp;María Jesús Rodríguez Revuelta","doi":"10.1016/j.anpede.2024.10.003","DOIUrl":"10.1016/j.anpede.2024.10.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Respiratory distress syndrome (RDS) is the most frequent cause of respiratory distress in preterm neonates. In the management of RDS, surfactant plays a pivotal role, but there are no evidence-based recommendations for moderate/late preterm neonates (32–36 weeks).</div></div><div><h3>Methods</h3><div>A scientific committee developed a questionnaire with 53 questions addressing diagnosis, treatment, potential complications and future trends in RDS specifically focused on moderate and late preterm neonates. This was followed by the performance of a Delphi survey of expert neonatologists.</div></div><div><h3>Results</h3><div>Consensus was reached on 98 of the 109 items. The recommendations for the diagnosis of RDS included performing a lung ultrasound and including mild respiratory distress, transient tachypnoea of the newborn, congenital pneumonia and primary pulmonary hypertension in the differential diagnosis. Most panellists agreed on the need for studies that determine the benefit/harm balance, clinical profile and methods of surfactant administration in moderate/late preterm neonates. All respondents would use the MIST approach with devices specifically designed for surfactant administration. Regarding sedation measures during MIST, most participants agreed on the use of nonpharmacological interventions and, if these proved ineffective, an opioid. All respondents agreed that moderate/late preterm neonates are at increased risk of neonatal morbidity and mortality, particularly respiratory problems, and considered the need for more specialised monitoring in hospital follow-up visits in neonates with associated risk factors or a history of complications in the neonatal period. Finally, all respondents agreed that there is a lack of studies identifying risk factors and medium-term adverse outcomes in moderate/late preterm neonates.</div></div><div><h3>Conclusion</h3><div>This expert consensus will help with the diagnosis and management of RDS and guide decision-making about surfactant administration in moderate/late preterm neonates.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 5","pages":"Pages 319-330"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nutritional status in patients with protein metabolism disorders. Case-control study","authors":"Isidro Robredo García ,&nbsp;Paula Grattarola ,&nbsp;Patricia Correcher Medina ,&nbsp;Fátima Abu-Sharif Bohigas ,&nbsp;Verónica Vélez García ,&nbsp;Isidro Vitoria Miñana ,&nbsp;Cecilia Martínez Costa","doi":"10.1016/j.anpede.2024.10.012","DOIUrl":"10.1016/j.anpede.2024.10.012","url":null,"abstract":"<div><h3>Introduction</h3><div>Patients with protein metabolism disorders (PMDs) require a diet with strict protein control that can affect their growth and development. The aim of the study was to assess nutritional status and growth in patients with PMDs undergoing dietary treatment.</div></div><div><h3>Patients and methods</h3><div>Prospective observational case-control study in 63 patients with PMDs and 63 healthy controls matched for age and sex. We collected data for anthropometric variables (weight, height, BMI, tricipital and subscapular skinfolds, arm and waist circumference) and calculated the corresponding <em>z</em> scores. We also estimated the body fat mass and classified patients into nutritional status categories.</div></div><div><h3>Results</h3><div>The overall analysis found a lower height <em>z</em> score in patients with PMDs and an equal proportion of overweight and obesity with respect to controls (30.2%). When we divided patients with PMDs into 2 groups (phenylketonuria and other aminoacidopathies), we found that patients with phenylketonuria had a height that was similar to the height of controls and significantly higher compared to patients with other aminoacidopathies. When it came to nutritional status, the prevalence of overweight and obesity was greater in the phenylketonuria group (45.5%), while underweight and short stature were more frequent in the group with other aminoacidopathies.</div></div><div><h3>Conclusion</h3><div>Not all patients with PMDs follow the same growth pattern, and their body composition is variable. In our sample, the group of patients with phenylketonuria had an adequate height but also a higher prevalence of overweight and obesity. On the other hand, patients with other aminoacidopathies had a higher prevalence of underweight and lower <em>z</em> scores for height and arm circumference.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 5","pages":"Pages 331-336"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of passive smoking exposure in Pediatric Primary Care Consultations: BACCO study","authors":"María Almudena Santos Sánchez-Rey ,&nbsp;Irene Zamanillo Herreros ,&nbsp;Aida Frías González ,&nbsp;María Rosa Albañil Ballesteros","doi":"10.1016/j.anpede.2024.10.007","DOIUrl":"10.1016/j.anpede.2024.10.007","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 5","pages":"Pages 353-355"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary ciliary dyskinesia: additional diagnosis in a patient with cardiospondylocarpofacial syndrome","authors":"Patricia Morte-Coscolín ,&nbsp;Sandra Rovira-Amigo ,&nbsp;Carlos Martín-de Vicente","doi":"10.1016/j.anpede.2024.10.010","DOIUrl":"10.1016/j.anpede.2024.10.010","url":null,"abstract":"","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 5","pages":"Pages 357-359"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The minor in Spanish legislation: an ethics perspective","authors":"María Alija ,&nbsp;Isolina Riaño ,&nbsp;Montserrat Esquerda","doi":"10.1016/j.anpede.2024.08.007","DOIUrl":"10.1016/j.anpede.2024.08.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Legislation embodies and regulates the common values by which a society is governed. Today’s society is multicultural and dynamic, a consensus must be reached and values consolidated on which different ideological groups can agree, an approach known as the ethics of minima. The concept of the minor has also been changing over the years; from being perceived as passive to being considered an autonomous individual engaged in the development of his or her life project and the bearer of duties and rights to be progressively exercised according to his or her capacity. This approach entails emerging problems. Both aspects need to be regulated in our legislation.</div></div><div><h3>Objective</h3><div>The objective of this work was to consider the different laws that concern minors from an ethical perspective and from the point of view of the practicing paediatrician.</div></div><div><h3>Material and methods</h3><div>We reviewed legislation concerning minors from the 1990s to the present day. For the purpose of discussion, we grouped it into 4 sections: the minor as a patient, protection of the minor, education and new social realities.</div></div><div><h3>Conclusions</h3><div>Current laws reflect a plural society and focus on protecting minority groups. They recognize the minor as the bearer of rights and duties, and consider the acquisition of autonomy to be progressive, guaranteeing equal opportunity and respecting the child’s own pace in achieving his or her potential. Current legislation also stresses the need for a stable environment and states that all forms of violence are preventable. Furthermore, it respects different moral, social and cultural perspectives.</div></div>","PeriodicalId":93868,"journal":{"name":"Anales de pediatria","volume":"101 5","pages":"Pages 337-343"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142634330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}