Acta bio-medica : Atenei Parmensis最新文献_第3页

Not only enuresis: do not disregard organic disorders. 不仅是遗尿症：不要忽视器质性疾病。

Acta bio-medica : Atenei Parmensis Pub Date : 2023-12-05 DOI: 10.23750/abm.v94i6.14931

Pietro Ferrara, Giovanna Magli, Elena Malavolta, Emidio Procaccini, Luca Massimi, Antonio Gatto

{"title":"Not only enuresis: do not disregard organic disorders.","authors":"Pietro Ferrara, Giovanna Magli, Elena Malavolta, Emidio Procaccini, Luca Massimi, Antonio Gatto","doi":"10.23750/abm.v94i6.14931","DOIUrl":"10.23750/abm.v94i6.14931","url":null,"abstract":"Nocturnal enuresis (NE) is a common condition in the pediatric age. NE is defined as an intermittent bedwetting with any frequency while sleeping in children. NE is classified into primary form (patient never had achieved nocturnal urinary control) or secondary form (children with a period of 6 consecutive months of night-time urinary control before incontinence, which is generally associated with organic or psychological causes). Moreover, NE could be monosymptomatic (MNE) or non-monosymptomatic (NMNE), depending on the presence of daytime incontinence or any other lower urinary tract symptoms (LUTS). We report a 7-year- old female with a history of recent onset of sphincter troubles and recurrent low urinary tract infections. She presented urinary urgency associated to daytime incontinence, bedwetting almost every night in the previous 3 months and sometimes encopresis. The physical and neurological examination was silent, no psychological or social problem intercurred. As first approach, she was treated with deamino-delta-D-arginine vasopressin (dDAVP) 120 mcg associated with oxybutynin 5 mg and educational therapy, for 3 months without benefits. So, she underwent a magnetic resonance imaging (MRI) of the spinal cord, that highlighted the presence of hydrosyringomyelia from D6 to D10, lipoma of the terminal filum and the presence of synovial cyst between L5-S1. This case remarks that in secondary NMNE, any possible organic cause must be investigated.","PeriodicalId":93849,"journal":{"name":"Acta bio-medica : Atenei Parmensis","volume":"94 6","pages":"e2023223"},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10734227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138489335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-recoverin antibodies in a cerebellar syndrome without retinal involvement. 无视网膜受累的小脑综合征中的抗复原素抗体。

Acta bio-medica : Atenei Parmensis Pub Date : 2023-12-05 DOI: 10.23750/abm.v94i6.15234

Matteo Minetti, Giulia Balella, Lucia Zinno

引用次数: 0

Antibiotic treatment for streptococcal pharyngitis: time for a new approach? 链球菌性咽炎的抗生素治疗：是时候采用新方法了吗？

Acta bio-medica : Atenei Parmensis Pub Date : 2023-12-05 DOI: 10.23750/abm.v94i6.14928

Lorenzo Di Sarno, Antonietta Curatola, Valeria Pansini, Anya Caroselli, Antonio Gatto, Antonio Chiaretti

引用次数: 0

Outcome of simultaneous bi-unicompartmental knee arthroplasty: a systematic review. 同步双双室膝关节置换术的效果：系统性综述。

Acta bio-medica : Atenei Parmensis Pub Date : 2023-12-05 DOI: 10.23750/abm.v94i6.15006

Ibrahim Akkawi, Maurizio Draghetti, Hassan Zmerly

{"title":"Outcome of simultaneous bi-unicompartmental knee arthroplasty: a systematic review.","authors":"Ibrahim Akkawi, Maurizio Draghetti, Hassan Zmerly","doi":"10.23750/abm.v94i6.15006","DOIUrl":"10.23750/abm.v94i6.15006","url":null,"abstract":"Background and aim: Simultaneous medial and lateral tibiofemoral osteoarthritis (OA) could be treated with bi-unicompartmental knee arthroplasty (Bi-UKA) as an alternative to total knee arthroplasty (TKA). The present systematic review aims to assess if simultaneous Bi-UKA is a feasible option for treating medial and lateral tibiofemoral OA.Materials and methods: A comprehensive search of PubMed, MEDLINE, Cochrane Library, and Google Scholar was performed to find studies that reported on the outcome of simultaneous Bi-UKA for both medial and lateral tibiofemoral OA.Results: Seven studies were considered eligible for inclusion in the present systematic review. Intraoperative fractures occurred 8 times. Overall, there were 22 revisions of the prosthetic components for any reason with a survival rate that ranged from 83 to 100%. Of these, 16 revisions were for the aseptic loosening of the prosthetic components. Out of 302 surgeries, three were revised due to symptomatic OA progression in the patello-femoral joint. All clinical scores improved at the latest follow-up compared to preoperative values. Moreover, there were no differences in clinical scores of Bi-UKA compared to unicompartmental knee arthroplasty (UKA), or medial UKA plus patello-femoral prosthesis. Whereas, compared to TKA, Bi-UKA patients had comparable or superior scores. Finally, the Bi-UKA group had a significantly shorter hospital stay compared to the TKA group.Conclusions: The use of simultaneous Bi-UKA is a valid option to address bicompartmental knee OA in selected patients with low intraoperative fracture rate, low revision rate, satisfactory clinical outcome, and fast recovery.","PeriodicalId":93849,"journal":{"name":"Acta bio-medica : Atenei Parmensis","volume":"94 6","pages":"e2023240"},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10734244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138489337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between severity of sepsis and thyroid function profile. 败血症严重程度与甲状腺功能状况之间的关系

Acta bio-medica : Atenei Parmensis Pub Date : 2023-12-05 DOI: 10.23750/abm.v94i6.15076

Vindy Nugraha Siampa, Satriawan Abadi, Andi Makbul Aman, Syakib Bakri, Risna Halim, Andi Alfian Zainuddin

{"title":"Association between severity of sepsis and thyroid function profile.","authors":"Vindy Nugraha Siampa, Satriawan Abadi, Andi Makbul Aman, Syakib Bakri, Risna Halim, Andi Alfian Zainuddin","doi":"10.23750/abm.v94i6.15076","DOIUrl":"10.23750/abm.v94i6.15076","url":null,"abstract":"Background and aim: Critical illness conditions such as sepsis are often accompanied by altered hormone levels, which may result in decreased thyroid axis activity. This condition aims to provide metabolic substrates for vital organs such as the brain and immune system. Significant alteration of the thyroid axis in critical illnesses such as sepsis known as Low-T3 Syndrome which is associated with increased mortality. This study aims to determine the association between severity of sepsis and thyroid function profile as a predictor of mortality in sepsis patients.Methods: An observational study involving 62 subjects with sepsis and septic shock. Serum was measured using Enzyme-linked Immunosorbent Assay (ELISA) method. Statistical analysis used Mann-Whitney, Kruskal-Wallis, and Spearman's correlation tests. Statistical test results are significant if the p-value <0.05.Results: The median fT3 level was lower in the septic shock group 13.94 pg/ml (7.71-19.93) compared to the sepsis group 20.15 pg/ml (11.08-37.15) where there was a significant difference (p<0.001). There was a significant correlation between The Sequential Organ Failure Assessment (SOFA) score and fT3 levels (R: -0.270, p=0.032). The non-survivor group had a lower median fT3 level 16.56 pg/ml (7.71-30.03) compared to the survivor group 17.50 pg/ml (10.32-37.15) where there was a significant difference (p<0.036).Conclusion: Based on the severity of sepsis, the more severe the sepsis condition, the lower thyroid function levels are obtained where decreased thyroid function levels can be a prognosis indicator to predict mortality in sepsis patients.","PeriodicalId":93849,"journal":{"name":"Acta bio-medica : Atenei Parmensis","volume":"94 6","pages":"e2023239"},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10734233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138489265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dyspepsia in the middle ages: a reference in Giovanni Boccaccio's Decameron (14th century AD)? 中世纪的消化不良：乔瓦尼-薄伽丘的《十日谈》（公元 14 世纪）中的参考文献？

Acta bio-medica : Atenei Parmensis Pub Date : 2023-12-05 DOI: 10.23750/abm.v94i6.15137

Francesco Maria Galassi, Giovanni Spani, Michael Papio, Fabrizio Toscano, Marco Artico, Elena Varotto

引用次数: 0

Long-term health consequences of central precocious/early puberty (CPP) and treatment with Gn-RH analogue: a short update. 中枢性性早熟（CPP）和 Gn-RH 类似物治疗对健康的长期影响：简短更新。

Acta bio-medica : Atenei Parmensis Pub Date : 2023-12-05 DOI: 10.23750/abm.v94i6.15316

Ashraf T Soliman, Nada Alaaraj, Vincenzo De Sanctis, Noor Hamed, Fawzia Alyafei, Shayma Ahmed

{"title":"Long-term health consequences of central precocious/early puberty (CPP) and treatment with Gn-RH analogue: a short update.","authors":"Ashraf T Soliman, Nada Alaaraj, Vincenzo De Sanctis, Noor Hamed, Fawzia Alyafei, Shayma Ahmed","doi":"10.23750/abm.v94i6.15316","DOIUrl":"10.23750/abm.v94i6.15316","url":null,"abstract":"Background: The relationship between precocious or early puberty and its treatment has received significant research attention, yielding diverse outcomes. This short review aims to comprehensively analyze and summarize research articles to elucidate the potential link between precocious or early pubertal onset (CPP) and crucial health factors.Methods: We conducted a systematic review of studies published from -January 2000 to March 2023, sourced from databases of Medline, PubMed, Google Scholar and Web of Science. We assessed the relationship between CPP and final adult height (FHt), bone health, reproductive function, body mass index, metabolic and cardiovascular abnormalities, and increased cancer risk.Results: Upon reviewing and analyzing selected studies, the following key findings emerged: (a) treating CPP in girls before age 6-7 and in boys before age 9 improves FHt; (b) bone mineral density (BMD) decreases during GnRHa treatment but normalizes afterward, with no lasting effects on peak bone mass during puberty; (c) GnRH treatment does not negatively affect menstrual cycles; however, untreated CPP increases the risk of premature or early-onset menopause; (d) the incidence of PCOS/hyperandrogenemia may be slightly elevated in women with a history of CPP, but overall reproductive function remains largely unaffected; (e) earlier thelarche and menarche may enhance susceptibility to breast carcinogenesis; (f) CPP contributes to an increased risk of obesity and type 2 diabetes in both genders; (g) early menarche may slightly increase the risk of coronary heart disease and ischemic strokes and (h) early pubertal timing increases the risk of depression and anxiety disorders.Conclusion: Monitoring and early diagnosis of these conditions are of paramount importance for successful management.","PeriodicalId":93849,"journal":{"name":"Acta bio-medica : Atenei Parmensis","volume":"94 6","pages":"e2023222"},"PeriodicalIF":0.0,"publicationDate":"2023-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10734238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138489297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Open Technique. 开放技术。

Acta bio-medica : Atenei Parmensis Pub Date : 2023-10-17 DOI: 10.23750/abm.v94i5.13541

Renato Costi, Manuel Baldinu, Filippo Montali, Alfredo Annicchiarico

引用次数: 0

Clinical and epidemiological features and therapeutic options of avascular necrosis in patients with sickle cell disease (SCD): a cross-sectional study. 镰状细胞病（SCD）患者缺血性坏死的临床和流行病学特征及治疗选择：一项横断面研究。

Acta bio-medica : Atenei Parmensis Pub Date : 2023-10-17 DOI: 10.23750/abm.v94i5.14603

Awni Alshurafa, Ashraf T Soliman, Vincenzo De Sanctis, Omar Ismail, Mohammad Abu-Tineh, Mohammad Khair Eddin Hemadneh, Farah Rahat Rashid, Khadra Yassin, Hana Qasim, Abdulqadir Jeprel Nashwan, Mohamed A Yassin

{"title":"Clinical and epidemiological features and therapeutic options of avascular necrosis in patients with sickle cell disease (SCD): a cross-sectional study.","authors":"Awni Alshurafa, Ashraf T Soliman, Vincenzo De Sanctis, Omar Ismail, Mohammad Abu-Tineh, Mohammad Khair Eddin Hemadneh, Farah Rahat Rashid, Khadra Yassin, Hana Qasim, Abdulqadir Jeprel Nashwan, Mohamed A Yassin","doi":"10.23750/abm.v94i5.14603","DOIUrl":"10.23750/abm.v94i5.14603","url":null,"abstract":"Background: Avascular necrosis (AVN) is a debilitating complication in sickle cell disease (SCD) patients, and its management is usually challenging. This study aims to evaluate the clinical and epidemiological features and therapeutic options of AVN in sickle cell patients in Qatar.Patients and methods: A cross-sectional study was conducted on a 49 SCD patients who were diagnosed with AVN and attended the hematology clinic at the National Center for Cancer care & research, Hamad Medical Corporation, Qatar between Jan-2011 to Jan2021. Results: Forty-nine adult patients with SCD who were diagnosed with AVN were studied. The median age of the study population is 32 years, and the median age at the first AVN diagnosis was 26 years (range: 11-44 yr.). 37 (75.5%) patients suffered from multiple joints AVN while 12(24.5%) had single joint involvement. 31 (63.3%) patients had bilateral hip AVN and 18 (36.7%) had shoulder involvement. 30 patients (61%) were on Hydroxyurea treatment. Based on FICAT and Alert classification of AVN, 57 % of patients had stage III and above at first diagnosis. 20 (40.8%) were managed with a conservative approach, 11 (22.4%) received hyperbaric oxygen with good response, 6(12.2%) underwent hip core decompression and 12(24.5%) underwent hip replacement surgery.Conclusion: In SCD patients, AVN occurred more during the 3rd and 4th decades of life. The majority of AVN represented with advanced stage and had multiple joint involvements. We recommend adopting a low threshold of joint imaging for early detection and prevention of further complications.","PeriodicalId":93849,"journal":{"name":"Acta bio-medica : Atenei Parmensis","volume":"94 5","pages":"e2023198"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of genotypic and phenotypic antimicrobial profile in carbapenemases producing Klebsiella pneumoniae. 产碳青霉烯酶肺炎克雷伯菌的基因型和表型抗菌谱的比较。

Acta bio-medica : Atenei Parmensis Pub Date : 2023-10-17 DOI: 10.23750/abm.v94i5.14412

Arcadia Del Rio, Mariangela Puci, Narcisa Muresu, Illari Sechi, Laura Saderi, Luigi Cugia, Giovanni Sotgiu, Andrea Piana

{"title":"Comparison of genotypic and phenotypic antimicrobial profile in carbapenemases producing Klebsiella pneumoniae.","authors":"Arcadia Del Rio, Mariangela Puci, Narcisa Muresu, Illari Sechi, Laura Saderi, Luigi Cugia, Giovanni Sotgiu, Andrea Piana","doi":"10.23750/abm.v94i5.14412","DOIUrl":"10.23750/abm.v94i5.14412","url":null,"abstract":"Background and aim: Prompt administration of appropriate antibiotic therapy is crucial in improving outcomes, particularly in cases sustained by multi-drug resistant strains. Although phenotypic antimicrobial susceptibility testing (AST) represents the gold standard to address antibiotics treatment, the long time required to obtained affordable results could negatively affect the prognosis. In contrast, rapid genotypic AST provide essential information for treatment and surveillance program. In order to evaluate the potential adoption of rapid AST in clinical routine, we compared the genotypic and phenotypic antimicrobial profiles of different K.pneumoniae strains, characterized by different expression of carbapenemases-encoding genes.Methods: A set of 109 strains of Cr-Kp were tested for the antimicrobial drugs by the automatized Vitek II system and, in parallel, to the new combination of β-lactams/β-lactamases inhibitors (BL/BLI) by Etest. An antimicrobial resistance index (ARI) was calculated for each strain, assigning each 1 or 0 points based on observed resistance/susceptibility, and dividing the total by the number of antibiotics tested. Kruskal-Wallis test, followed by Dunn's post hoc test (Bonferroni correction), were used to compare quantitative variables among resistance gene subgroups.Results: We observed a higher ARI score in KPC/OXA-48 strains, similar profile in KPC alone and KPC/CTX-M groups and a significant lower resistance in no-carbapenemases-producing group. Same trend was observed in AST for BL/BLI.Conclusions: These preliminary results showed a close link between genotypic and phenotypic AST, supporting the adoption of rapid AST in cases of severe infections, ensuring to saving time and providing, the surveillance of MDR strains and improving stewardship programs.","PeriodicalId":93849,"journal":{"name":"Acta bio-medica : Atenei Parmensis","volume":"94 5","pages":"e2023201"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0