Adam Harkiewicz, George Martin, T. Dickerson, Ann Deren-Lewis
{"title":"A Survey of Nurse Practitioner and Physician Assistant Advanced Practice Providers Uncovers a Need for Precision Medicine in Psoriasis Management","authors":"Adam Harkiewicz, George Martin, T. Dickerson, Ann Deren-Lewis","doi":"10.58744/001c.84280","DOIUrl":"https://doi.org/10.58744/001c.84280","url":null,"abstract":"The arrival of biologics has considerably improved the treatment of psoriasis and psoriatic arthritis; however, it can be difficult to identify which biologic(s) a patient will respond to without undergoing a trial-and-error approach. The current survey was designed to investigate biologic switching in the clinic and whether a biomarker test would assist in selecting the appropriate treatment for patients and improve psoriasis management. A survey of 157 nurse practitioner and physician assistant (NP/PA) advanced practice providers was conducted to assess (1) the frequency of biologic switching and (2) the perceived clinical utility of a biomarker test that stratifies psoriasis patients to predict biologic response. More than half of advanced practice providers (55%) indicated that psoriasis patients require at least two different biologics to achieve an adequate response to treatment, with 59% of respondents specifying that 10% to 30% of their patients switch biologics the first year of treatment. Ninety-six percent of respondents indicated that a biomarker test would likely improve their practice, with the majority of participants (84%) suggesting a biomarker test could improve their ability to determine the most appropriate therapy for their patients. Ninety-one percent indicated they would use a biomarker test (Mind.Px, Mindera Health, San Diego, California), and 63% said they would perform the test in their office. A biomarker test may help shift psoriasis management from a trial-and-error approach to precision care, thereby reducing the time to effective treatment and improving patient outcomes.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88769461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Amplifying Our Collective Voice: Seasoned Derm PA Who Wrote First Prescription Following PA Prescribing Authority Law in Maryland Shares Experience, Advice","authors":"Mallory Aycock","doi":"10.58744/001c.85086","DOIUrl":"https://doi.org/10.58744/001c.85086","url":null,"abstract":"JDPA Editorial Board Member Mallory Aycock, MPA, PA-C, interviews Esther Cohen, PA-C, recipient of SDPA’s Joe Monroe Lifetime Achievement Award. Esther has dedicated her life to the advancement of dermatology PAs. She graduated from PA school in 1974 and by 1980 was the one of the first dermatology PAs in the country at Johns Hopkins in Baltimore, Maryland. She has practiced clinical dermatology for 43 years.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73899419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Addressing the Productivity-Salary Gap for PAs in Healthcare","authors":"Cynthia F. Griffith","doi":"10.58744/001c.84327","DOIUrl":"https://doi.org/10.58744/001c.84327","url":null,"abstract":"There is a need to address the productivity-salary gap for PAs in healthcare. This can be achieved by implementing transparent billing practices and adjusting PA salaries to reflect their contributions to patient care. By doing so, PAs can be compensated in proportion to their professional efforts caring for patients.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90087245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond the Surface: The Psychosocial Effects of Atopic Dermatitis","authors":"Kara Mudd","doi":"10.58744/001c.84270","DOIUrl":"https://doi.org/10.58744/001c.84270","url":null,"abstract":"The purpose of this article is to review the psychosocial effects of atopic dermatitis. It is important for providers to identify the psychosocial comorbidities associated with atopic dermatitis to provide well rounded patient care. A PubMed literature search was conducted with search terms “atopic dermatitis,” “psychosocial,” and “comorbidities.” Filters were set to articles published after 2015 and limited to clinical and systematic reviews, meta-analysis, and clinical trials. This yielded nine articles. A second search was performed using the terms “atopic dermatitis,” “anxiety,” and “depression” with similar parameters and 41 studies were revealed. Additional searches were performed in Medline and the Cochrane library with the same key terms. Several quality studies showed that atopic dermatitis is associated with increased risk of anxiety, depression, attention deficit hyperactivity disorder, suicidality, and decreased quality of life. Additional research is needed to determine the relationship between atopic dermatitis and obsessive-compulsive disorder, and schizophrenia. Many studies proposed pruritus and sleep deprivation as primary factors in increasing mental health comorbidities of atopic dermatitis. Dermatology providers should screen for associated comorbidities of atopic dermatitis and refer for appropriate treatment as necessary. Aggressive treatment of atopic dermatitis can improve overall quality of life and subsequently lessen the rate of associated comorbidities.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76800005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to Conduct a Review of the Literature","authors":"P. Jones","doi":"10.58744/001c.85085","DOIUrl":"https://doi.org/10.58744/001c.85085","url":null,"abstract":"A review of the literature is a summary of the current understanding of a specific topic or condition that serves to educate and/or aid the reader by presenting and synthesizing previously published scholarly sources. This article discusses how to conduct a literature review using current databases to collect and evaluate a range of sources, such as peer-reviewed professional and academic journal articles and textbooks and organize findings into a manuscript.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"149 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72429144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unlocking the Power of Purpose: Simon Sinek’s “Start with Why” and the Evolving Nature of Our Why","authors":"Lauren E. Miller","doi":"10.58744/001c.85089","DOIUrl":"https://doi.org/10.58744/001c.85089","url":null,"abstract":"Lauren E. Miller, MPAS, PA-C, SDPA President (2022-2023), discusses finding and connecting with “why,” meaning the purpose and values of a person and mission of an organization. This concept, which comes from the book Start with Why: How Great Leaders Inspire Everyone to Take Action, by Simon Sinek, has been a guiding light during Miller’s presidency.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80271984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Botox: Beauty and Brains","authors":"Donell D. Deremer","doi":"10.58744/001c.84325","DOIUrl":"https://doi.org/10.58744/001c.84325","url":null,"abstract":"Botulinum toxins (BTX), predominately BotulinumtoxinA, have been used for medical and aesthetic purposes since 1997. With nearly eight billion treatments performed worldwide for aesthetic purposes alone, there is extensive post-market experience with this drug. The known mechanism of action (MOA) of the local neurotransmitter blockade of acetylcholine lasts approximately 90 days. However, patients frequently report symptom and wrinkle relief beyond the 90-day period. There is extensive evidence that peripherally injected BTX, even at low aesthetic doses, induces structural and functional changes in the human brain. The MOA in the central nervous system (CNS) is presently unclear, with several proposed hypotheses to include the Social Feedback Hypothesis (SFH), Facial Feedback Hypothesis (FFH) and Emotional Proprioception (EP), Monoamine Theory and Brain-Derived Neurotrophic Peptide (BDFP), and Neuronal Transport Hypothesis. With the ability to modify the CNS, BTX for aesthetic use may become a novel treatment for CNS disorders, such as major depressive disorder (MDD). Over 30% of persons diagnosed with MDD had inadequate response to first-line treatments. Over 30% of persons diagnosed with treatment resistant depression (TRD) attempt suicide. BotulinumtoxinA may offer an effective adjunctive treatment of MDD/TRD.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87568371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Society of Dermatology Physician Assistants Summer 2023 Digital Abstracts","authors":"","doi":"10.58744/001c.85087","DOIUrl":"https://doi.org/10.58744/001c.85087","url":null,"abstract":"SDPA Presents Summer 2023 Digital Abstracts from SDPA Annual Summer Dermatology Conference June 22-25, 2023, Westin Copley Place, Boston, Massachusetts","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72677707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dermatologic Manifestations of Common Zoonotic Exposures","authors":"Janelle Bludorn, E. Palmer, Andre Braima","doi":"10.58744/001c.84259","DOIUrl":"https://doi.org/10.58744/001c.84259","url":null,"abstract":"Snakes, spiders, and ticks are among the most common creatures in the United States whose bites can lead to serious medical complications. Although the systemic sequelae are often nonspecific, many of these zoonotic exposures exhibit specific dermatologic manifestations that can be key to their diagnosis and treatment. The goal of this article is to increase clinician knowledge and skill in identifying the dermatologic findings of several snake-, spider-, and tick-borne conditions in order to provide prompt disease-specific medical treatment.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89348406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biologics and Psoriasis: Treatment Selection with a Focus on Patient Comorbidities","authors":"Eduardo A. Michelen-Gómez, Z. C. Chiesa Fuxench","doi":"10.58744/001c.73861","DOIUrl":"https://doi.org/10.58744/001c.73861","url":null,"abstract":"Psoriasis is a chronic, multisystemic, inflammatory disease that exhibits a wide array of clinical presentations and is associated with high disease burden. Advancements in our understanding of the pathophysiology of psoriasis have led to the development of novel therapeutic modalities known as biologics that inhibit the action of pro-inflammatory cytokines, offering a more targeted therapeutic approach and improved safety profile compared to traditional systemic agents. Psoriasis disease severity is usually the main driver when it comes to selecting the appropriate biologic for any given patient; however, with an increasing number of biologics from which to choose, one pressing question that is increasingly more common in clinical practice is, “How do we select the ‘right’ treatment for each patient?” We performed a review of the literature on biologic use in patients with psoriasis with a focus on specific systemic comorbidities. Here, we summarize currently available recommendations based on available studies.","PeriodicalId":93653,"journal":{"name":"Journal of dermatology for physician assistants : Official journal of the Society of Dermatology Physician Assistants","volume":"145 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79720348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}