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Public Awareness of Forensic Science and Willingness to Contribute to the DNA Database: A Study in Pakistan 公众对法医科学的认识和对DNA数据库贡献的意愿:巴基斯坦的一项研究
Forensic genomics Pub Date : 2021-12-09 DOI: 10.1089/forensic.2021.0010
R. Mateen, Asma Tariq, Guhlam Nabi Ahmed, Amer Afnan, Parveen Rukhsana
{"title":"Public Awareness of Forensic Science and Willingness to Contribute to the DNA Database: A Study in Pakistan","authors":"R. Mateen, Asma Tariq, Guhlam Nabi Ahmed, Amer Afnan, Parveen Rukhsana","doi":"10.1089/forensic.2021.0010","DOIUrl":"https://doi.org/10.1089/forensic.2021.0010","url":null,"abstract":"","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74305116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Convergence of Two Disciplines: Why Clinical Diagnostic Molecular Science Trainees Would Make Strong Forensic Technologists 两门学科的融合:为什么临床诊断分子科学培训生会成为强大的法医学专家
Forensic genomics Pub Date : 2021-12-08 DOI: 10.1089/forensic.2021.0012
I. Newsham, Peter Hu
{"title":"The Convergence of Two Disciplines: Why Clinical Diagnostic Molecular Science Trainees Would Make Strong Forensic Technologists","authors":"I. Newsham, Peter Hu","doi":"10.1089/forensic.2021.0012","DOIUrl":"https://doi.org/10.1089/forensic.2021.0012","url":null,"abstract":"","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80162734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genomics is Critical for Inferring the Historical Origins of Unknown Persons 基因组学是推断未知人物历史起源的关键
Forensic genomics Pub Date : 2021-12-01 DOI: 10.1089/forensic.2021.29008.mit
D. Mittelman
{"title":"Genomics is Critical for Inferring the Historical Origins of Unknown Persons","authors":"D. Mittelman","doi":"10.1089/forensic.2021.29008.mit","DOIUrl":"https://doi.org/10.1089/forensic.2021.29008.mit","url":null,"abstract":"","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82060092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genomic Readings Help Make Sense of Dead Sea Scrolls 基因组读数有助于理解死海古卷
Forensic genomics Pub Date : 2021-11-25 DOI: 10.1089/forensic.2021.29007.km
K. Mayer
{"title":"Genomic Readings Help Make Sense of Dead Sea Scrolls","authors":"K. Mayer","doi":"10.1089/forensic.2021.29007.km","DOIUrl":"https://doi.org/10.1089/forensic.2021.29007.km","url":null,"abstract":"","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82147880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Call for Papers: Forensic Genomics 征文:法医基因组学
Forensic genomics Pub Date : 2021-11-08 DOI: 10.1089/forensic.2021.29006.cfp
David M. Mittleman
{"title":"Call for Papers: Forensic Genomics","authors":"David M. Mittleman","doi":"10.1089/forensic.2021.29006.cfp","DOIUrl":"https://doi.org/10.1089/forensic.2021.29006.cfp","url":null,"abstract":"","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81729300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Internal Validation of Reduced Polymerase Chain Reaction Volume for the Amplification of Nonquantified DNA Extracts from Reference Samples 减少聚合酶链反应体积用于扩增参考样品非定量DNA提取物的内部验证
Forensic genomics Pub Date : 2021-09-01 DOI: 10.1089/forensic.2021.0007
Muhammad Usman Iqbal, M. A. Butt, Nasir Siddique, Qazi Laeeque Ahmad, Sajjad Ahmad, M. Amjad, M. Tahir
{"title":"Internal Validation of Reduced Polymerase Chain Reaction Volume for the Amplification of Nonquantified DNA Extracts from Reference Samples","authors":"Muhammad Usman Iqbal, M. A. Butt, Nasir Siddique, Qazi Laeeque Ahmad, Sajjad Ahmad, M. Amjad, M. Tahir","doi":"10.1089/forensic.2021.0007","DOIUrl":"https://doi.org/10.1089/forensic.2021.0007","url":null,"abstract":"Introduction: The present study was conducted to validate the reduced PCR reaction volume of Globalfiler™ amplification kit for the amplification of non-quantified DNA from standard reference sampl...","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"91 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84383758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Technology Can Help Us Tackle the “Silent Mass Disaster” of Unidentified Persons 技术可以帮助我们解决身份不明者的“无声的大规模灾难”
Forensic genomics Pub Date : 2021-09-01 DOI: 10.1089/forensic.2021.29005.dm
David Mittelman
{"title":"Technology Can Help Us Tackle the “Silent Mass Disaster” of Unidentified Persons","authors":"David Mittelman","doi":"10.1089/forensic.2021.29005.dm","DOIUrl":"https://doi.org/10.1089/forensic.2021.29005.dm","url":null,"abstract":"","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79987197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epigenetic Forensics for Suspect Identification and Age Prediction. 表观遗传法医学用于嫌疑人识别和年龄预测。
Forensic genomics Pub Date : 2021-09-01 Epub Date: 2021-09-15 DOI: 10.1089/forensic.2021.0005
Jonathan Foox, Daniela Bezdan, Priyanka Vijay, Kylie Getz, Kamolwat Ratanachai, Justin W Davis, Keith Booher, Xiaojing Yang, Cem Meydan, Christopher E Mason
{"title":"Epigenetic Forensics for Suspect Identification and Age Prediction.","authors":"Jonathan Foox,&nbsp;Daniela Bezdan,&nbsp;Priyanka Vijay,&nbsp;Kylie Getz,&nbsp;Kamolwat Ratanachai,&nbsp;Justin W Davis,&nbsp;Keith Booher,&nbsp;Xiaojing Yang,&nbsp;Cem Meydan,&nbsp;Christopher E Mason","doi":"10.1089/forensic.2021.0005","DOIUrl":"https://doi.org/10.1089/forensic.2021.0005","url":null,"abstract":"<p><p><b>Background:</b> Genetic testing at crime scenes is an instrumental molecular technique to identify or eliminate suspects, as well as to overturn wrongful convictions. Yet, genotyping alone cannot reveal the age of a sample, which could help advance the utility of crime scene samples for suspect identification. The distribution of cytosine methylation within a DNA sample can be leveraged to determine the epigenetic age of someone's blood. <b>Methodology:</b> We sought to demonstrate the ability of DNA methylation markers to accurately discern the age of blood spots from an actual crime scene, a \"mock\" crime scene, and also from a tube of blood stored in ethylenediaminetetraacetic acid for >20 years. This was achieved by quantifying methylation within known age-associated genetic loci across each DNA sample. We observed a strong linear coefficient (0.91) and high overall correlation (<i>R</i> <sup>2</sup> = 0.963) between the known age of a sample and the predicted age. <b>Conclusion:</b> We show that novel methods for targeted methylation and low-input whole-genome bisulfite sequencing can enable a novel and improved forensic profile of a crime scene that discerns not only who was present at the crime, but also their age. Finally, we use this model to discern the age and provenance of a blood sample that was used in a criminal investigation.</p>","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"1 3","pages":"83-86"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8596498/pdf/forensic.2021.0005.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39645427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Interview with Daniel Hellwig, Laboratory Director, Intermountain Forensics 采访丹尼尔·海威格，山间法医实验室主任
Forensic genomics Pub Date : 2021-09-01 DOI: 10.1089/forensic.2021.29004.dm
D. Mittelman
{"title":"Interview with Daniel Hellwig, Laboratory Director, Intermountain Forensics","authors":"D. Mittelman","doi":"10.1089/forensic.2021.29004.dm","DOIUrl":"https://doi.org/10.1089/forensic.2021.29004.dm","url":null,"abstract":"","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"279 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77248701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigative Genetic Genealogy: Ethical, Legal, and Social Issues and Directions for Future Research 调查遗传谱系:伦理、法律和社会问题及未来研究方向
Forensic genomics Pub Date : 2021-09-01 DOI: 10.1089/forensic.2021.0008
J. McEwen, N. Pino, Alex Raphael, Kathleen Renna, Joy T. Boyer, L. Brody
{"title":"Investigative Genetic Genealogy: Ethical, Legal, and Social Issues and Directions for Future Research","authors":"J. McEwen, N. Pino, Alex Raphael, Kathleen Renna, Joy T. Boyer, L. Brody","doi":"10.1089/forensic.2021.0008","DOIUrl":"https://doi.org/10.1089/forensic.2021.0008","url":null,"abstract":"Investigative genetic genealogy—the use of direct-to-consumer genetic genealogy databases to assist in the resolution of crimes involving DNA evidence—holds tremendous potential for law enforcement...","PeriodicalId":93434,"journal":{"name":"Forensic genomics","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72514021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
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