BMC Medical Informatics and Decision Making最新文献

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Leveraging shortest dependency paths in low-resource biomedical relation extraction. 在低资源生物医学关系提取中利用最短依赖路径。
IF 3.3 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-24 DOI: 10.1186/s12911-024-02592-2
Saman Enayati, Slobodan Vucetic
{"title":"Leveraging shortest dependency paths in low-resource biomedical relation extraction.","authors":"Saman Enayati, Slobodan Vucetic","doi":"10.1186/s12911-024-02592-2","DOIUrl":"10.1186/s12911-024-02592-2","url":null,"abstract":"<p><strong>Background: </strong>Biomedical Relation Extraction (RE) is essential for uncovering complex relationships between biomedical entities within text. However, training RE classifiers is challenging in low-resource biomedical applications with few labeled examples.</p><p><strong>Methods: </strong>We explore the potential of Shortest Dependency Paths (SDPs) to aid biomedical RE, especially in situations with limited labeled examples. In this study, we suggest various approaches to employ SDPs when creating word and sentence representations under supervised, semi-supervised, and in-context-learning settings.</p><p><strong>Results: </strong>Through experiments on three benchmark biomedical text datasets, we find that incorporating SDP-based representations enhances the performance of RE classifiers. The improvement is especially notable when working with small amounts of labeled data.</p><p><strong>Conclusion: </strong>SDPs offer valuable insights into the complex sentence structure found in many biomedical text passages. Our study introduces several straightforward techniques that, as demonstrated experimentally, effectively enhance the accuracy of RE classifiers.</p>","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11267752/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shared decision-making endorses intention to follow through treatment or vaccination recommendations: a multi-method survey study among older adults. 共同决策会使老年人更愿意接受治疗或疫苗接种建议:一项针对老年人的多方法调查研究。
IF 3.3 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-23 DOI: 10.1186/s12911-024-02611-2
Tuuli Turja, Milla Rosenlund, Virpi Jylhä, Hanna Kuusisto
{"title":"Shared decision-making endorses intention to follow through treatment or vaccination recommendations: a multi-method survey study among older adults.","authors":"Tuuli Turja, Milla Rosenlund, Virpi Jylhä, Hanna Kuusisto","doi":"10.1186/s12911-024-02611-2","DOIUrl":"10.1186/s12911-024-02611-2","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have shown that shared decision-making (SDM) between a practitioner and a patient strengthens the ideal of treatment adherence. This study employed a multi-method approach to SDM in healthcare to reinforce the theoretical and methodological grounds of this argument. As the study design, self-reported survey items and experimental vignettes were combined in one electronic questionnaire. This technique aimed to analyze the effects of previous experiences and the current preferences regarding SDM on the intentions to follow-through with the medical recommendations.</p><p><strong>Method: </strong>Using quantitative data collected from the members of the Finnish Pensioners' Federation (N = 1610), this study focused on the important and growing population of older adults as healthcare consumers. Illustrated vignettes were used in the evaluation of expected adherence to both vaccination and the treatment of an illness, depending on the decision-making style varying among the repeated scenarios. In a within-subjects study design, each study subject acted as their own control.</p><p><strong>Results: </strong>The findings demonstrated that SDM correlates with expected adherence to a treatment and vaccination. Both the retrospective experiences and prospective aspirations of SDM in clinical encounters supported the patients' expected adherence to vaccination and treatment while decreasing the probability of pseudo-compliance. The association between SDM and expected adherence was not affected by the perceived health of the respondents. However, the associations among the expected adherence and decision-making styles were found to differ between the treatment and vaccination scenarios.</p><p><strong>Conclusions: </strong>SDM enables expected treatment adherence among older adults. Thus, the multi-method study emphasizes the importance of SDM in various healthcare encounters. The findings further imply that SDM research benefits from questionnaires combining self-report methods and experimental study designs. Further cross-validation studies using various types of written and illustrated scenarios are encouraged.</p>","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11264447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Second opinion machine learning for fast-track pathway assignment in hip and knee replacement surgery: the use of patient-reported outcome measures. 用于髋关节和膝关节置换手术快速通道分配的第二意见机器学习:使用患者报告的结果指标。
IF 3.3 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-23 DOI: 10.1186/s12911-024-02602-3
Andrea Campagner, Frida Milella, Giuseppe Banfi, Federico Cabitza
{"title":"Second opinion machine learning for fast-track pathway assignment in hip and knee replacement surgery: the use of patient-reported outcome measures.","authors":"Andrea Campagner, Frida Milella, Giuseppe Banfi, Federico Cabitza","doi":"10.1186/s12911-024-02602-3","DOIUrl":"10.1186/s12911-024-02602-3","url":null,"abstract":"<p><strong>Background: </strong>The frequency of hip and knee arthroplasty surgeries has been rising steadily in recent decades. This trend is attributed to an aging population, leading to increased demands on healthcare systems. Fast Track (FT) surgical protocols, perioperative procedures designed to expedite patient recovery and early mobilization, have demonstrated efficacy in reducing hospital stays, convalescence periods, and associated costs. However, the criteria for selecting patients for FT procedures have not fully capitalized on the available patient data, including patient-reported outcome measures (PROMs).</p><p><strong>Methods: </strong>Our study focused on developing machine learning (ML) models to support decision making in assigning patients to FT procedures, utilizing data from patients' self-reported health status. These models are specifically designed to predict the potential health status improvement in patients initially selected for FT. Our approach focused on techniques inspired by the concept of controllable AI. This includes eXplainable AI (XAI), which aims to make the model's recommendations comprehensible to clinicians, and cautious prediction, a method used to alert clinicians about potential control losses, thereby enhancing the models' trustworthiness and reliability.</p><p><strong>Results: </strong>Our models were trained and tested using a dataset comprising 899 records from individual patients admitted to the FT program at IRCCS Ospedale Galeazzi-Sant'Ambrogio. After training and selecting hyper-parameters, the models were assessed using a separate internal test set. The interpretable models demonstrated performance on par or even better than the most effective 'black-box' model (Random Forest). These models achieved sensitivity, specificity, and positive predictive value (PPV) exceeding 70%, with an area under the curve (AUC) greater than 80%. The cautious prediction models exhibited enhanced performance while maintaining satisfactory coverage (over 50%). Further, when externally validated on a separate cohort from the same hospital-comprising patients from a subsequent time period-the models showed no pragmatically notable decline in performance.</p><p><strong>Conclusions: </strong>Our results demonstrate the effectiveness of utilizing PROMs as basis to develop ML models for planning assignments to FT procedures. Notably, the application of controllable AI techniques, particularly those based on XAI and cautious prediction, emerges as a promising approach. These techniques provide reliable and interpretable support, essential for informed decision-making in clinical processes.</p>","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11267678/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141751174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Principles of digital professionalism for the metaverse in healthcare 医疗保健领域元世界的数字专业原则
IF 3.5 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-22 DOI: 10.1186/s12911-024-02607-y
Zahra Mohammadzadeh, Mehdi Shokri, Hamid Reza Saeidnia, Marcin Kozak, Agostino Marengo, Brady D Lund, Marcel Ausloos, Nasrin Ghiasi
{"title":"Principles of digital professionalism for the metaverse in healthcare","authors":"Zahra Mohammadzadeh, Mehdi Shokri, Hamid Reza Saeidnia, Marcin Kozak, Agostino Marengo, Brady D Lund, Marcel Ausloos, Nasrin Ghiasi","doi":"10.1186/s12911-024-02607-y","DOIUrl":"https://doi.org/10.1186/s12911-024-02607-y","url":null,"abstract":"Experts are currently investigating the potential applications of the metaverse in healthcare. The metaverse, a groundbreaking concept that arose in the early 21st century through the fusion of virtual reality and augmented reality technologies, holds promise for transforming healthcare delivery. Alongside its implementation, the issue of digital professionalism in healthcare must be addressed. Digital professionalism refers to the knowledge and skills required by healthcare specialists to navigate digital technologies effectively and ethically. This study aims to identify the core principles of digital professionalism for the use of metaverse in healthcare. This study utilized a qualitative design and collected data through semi-structured online interviews with 20 medical information and health informatics specialists from various countries (USA, UK, Sweden, Netherlands, Poland, Romania, Italy, Iran). Data analysis was conducted using the open coding method, wherein concepts (codes) related to the themes of digital professionalism for the metaverse in healthcare were assigned to the data. The analysis was performed using the MAXQDA software (VER BI GmbH, Berlin, Germany). The study revealed ten fundamental principles of digital professionalism for the metaverse in healthcare: Privacy and Security, Informed Consent, Trust and Integrity, Accessibility and Inclusion, Professional Boundaries, Evidence-Based Practice, Continuous Education and Training, Collaboration and Interoperability, Feedback and Improvement, and Regulatory Compliance. As the metaverse continues to expand and integrate itself into various industries, including healthcare, it becomes vital to establish principles of digital professionalism to ensure ethical and responsible practices. Healthcare professionals can uphold these principles to maintain ethical standards, safeguard patient privacy, and deliver effective care within the metaverse.","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141744450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interpretable machine learning models for detecting peripheral neuropathy and lower extremity arterial disease in diabetics: an analysis of critical shared and unique risk factors 用于检测糖尿病患者周围神经病变和下肢动脉疾病的可解释机器学习模型:对关键的共同和独特风险因素的分析
IF 3.5 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-22 DOI: 10.1186/s12911-024-02595-z
Ya Wu, Danmeng Dong, Lijie Zhu, Zihong Luo, Yang Liu, Xiaoyun Xie
{"title":"Interpretable machine learning models for detecting peripheral neuropathy and lower extremity arterial disease in diabetics: an analysis of critical shared and unique risk factors","authors":"Ya Wu, Danmeng Dong, Lijie Zhu, Zihong Luo, Yang Liu, Xiaoyun Xie","doi":"10.1186/s12911-024-02595-z","DOIUrl":"https://doi.org/10.1186/s12911-024-02595-z","url":null,"abstract":"Diabetic peripheral neuropathy (DPN) and lower extremity arterial disease (LEAD) are significant contributors to diabetic foot ulcers (DFUs), which severely affect patients’ quality of life. This study aimed to develop machine learning (ML) predictive models for DPN and LEAD and to identify both shared and distinct risk factors. This retrospective study included 479 diabetic inpatients, of whom 215 were diagnosed with DPN and 69 with LEAD. Clinical data and laboratory results were collected for each patient. Feature selection was performed using three methods: mutual information (MI), random forest recursive feature elimination (RF-RFE), and the Boruta algorithm to identify the most important features. Predictive models were developed using logistic regression (LR), random forest (RF), and eXtreme Gradient Boosting (XGBoost), with particle swarm optimization (PSO) used to optimize their hyperparameters. The SHapley Additive exPlanation (SHAP) method was applied to determine the importance of risk factors in the top-performing models. For diagnosing DPN, the XGBoost model was most effective, achieving a recall of 83.7%, specificity of 86.8%, accuracy of 85.4%, and an F1 score of 83.7%. On the other hand, the RF model excelled in diagnosing LEAD, with a recall of 85.7%, specificity of 92.9%, accuracy of 91.9%, and an F1 score of 82.8%. SHAP analysis revealed top five critical risk factors shared by DPN and LEAD, including increased urinary albumin-to-creatinine ratio (UACR), glycosylated hemoglobin (HbA1c), serum creatinine (Scr), older age, and carotid stenosis. Additionally, distinct risk factors were pinpointed: decreased serum albumin and lower lymphocyte count were linked to DPN, while elevated neutrophil-to-lymphocyte ratio (NLR) and higher D-dimer levels were associated with LEAD. This study demonstrated the effectiveness of ML models in predicting DPN and LEAD in diabetic patients and identified significant risk factors. Focusing on shared risk factors may greatly reduce the prevalence of both conditions, thereby mitigating the risk of developing DFUs.","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141744451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using machine learning-based algorithms to construct cardiovascular risk prediction models for Taiwanese adults based on traditional and novel risk factors 使用基于机器学习的算法,根据传统和新型风险因素为台湾成年人构建心血管风险预测模型
IF 3.5 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-22 DOI: 10.1186/s12911-024-02603-2
Chien-Hsiang Cheng, Bor-Jen Lee, Oswald Ndi Nfor, Chih-Hsuan Hsiao, Yi-Chia Huang, Yung-Po Liaw
{"title":"Using machine learning-based algorithms to construct cardiovascular risk prediction models for Taiwanese adults based on traditional and novel risk factors","authors":"Chien-Hsiang Cheng, Bor-Jen Lee, Oswald Ndi Nfor, Chih-Hsuan Hsiao, Yi-Chia Huang, Yung-Po Liaw","doi":"10.1186/s12911-024-02603-2","DOIUrl":"https://doi.org/10.1186/s12911-024-02603-2","url":null,"abstract":"To develop and validate machine learning models for predicting coronary artery disease (CAD) within a Taiwanese cohort, with an emphasis on identifying significant predictors and comparing the performance of various models. This study involved a comprehensive analysis of clinical, demographic, and laboratory data from 8,495 subjects in Taiwan Biobank (TWB) after propensity score matching to address potential confounding factors. Key variables included age, gender, lipid profiles (T-CHO, HDL_C, LDL_C, TG), smoking and alcohol consumption habits, and renal and liver function markers. The performance of multiple machine learning models was evaluated. The cohort comprised 1,699 individuals with CAD identified through self-reported questionnaires. Significant differences were observed between CAD and non-CAD individuals regarding demographics and clinical features. Notably, the Gradient Boosting model emerged as the most accurate, achieving an AUC of 0.846 (95% confidence interval [CI] 0.819–0.873), sensitivity of 0.776 (95% CI, 0.732–0.820), and specificity of 0.759 (95% CI, 0.736–0.782), respectively. The accuracy was 0.762 (95% CI, 0.742–0.782). Age was identified as the most influential predictor of CAD risk within the studied dataset. The Gradient Boosting machine learning model demonstrated superior performance in predicting CAD within the Taiwanese cohort, with age being a critical predictor. These findings underscore the potential of machine learning models in enhancing the prediction accuracy of CAD, thereby supporting early detection and targeted intervention strategies. Not applicable.","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141744453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DEL-Thyroid: deep ensemble learning framework for detection of thyroid cancer progression through genomic mutation DEL-甲状腺:通过基因组突变检测甲状腺癌进展的深度集合学习框架
IF 3.5 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-22 DOI: 10.1186/s12911-024-02604-1
Asghar Ali Shah, Ali Daud, Amal Bukhari, Bader Alshemaimri, Muhammad Ahsan, Rehmana Younis
{"title":"DEL-Thyroid: deep ensemble learning framework for detection of thyroid cancer progression through genomic mutation","authors":"Asghar Ali Shah, Ali Daud, Amal Bukhari, Bader Alshemaimri, Muhammad Ahsan, Rehmana Younis","doi":"10.1186/s12911-024-02604-1","DOIUrl":"https://doi.org/10.1186/s12911-024-02604-1","url":null,"abstract":"Genes, expressed as sequences of nucleotides, are susceptible to mutations, some of which can lead to cancer. Machine learning and deep learning methods have emerged as vital tools in identifying mutations associated with cancer. Thyroid cancer ranks as the 5th most prevalent cancer in the USA, with thousands diagnosed annually. This paper presents an ensemble learning model leveraging deep learning techniques such as Long Short-Term Memory (LSTM), Gated Recurrent Units (GRUs), and Bi-directional LSTM (Bi-LSTM) to detect thyroid cancer mutations early. The model is trained on a dataset sourced from asia.ensembl.org and IntOGen.org, consisting of 633 samples with 969 mutations across 41 genes, collected from individuals of various demographics. Feature extraction encompasses techniques including Hahn moments, central moments, raw moments, and various matrix-based methods. Evaluation employs three testing methods: self-consistency test (SCT), independent set test (IST), and 10-fold cross-validation test (10-FCVT). The proposed ensemble learning model demonstrates promising performance, achieving 96% accuracy in the independent set test (IST). Statistical measures such as training accuracy, testing accuracy, recall, sensitivity, specificity, Mathew's Correlation Coefficient (MCC), loss, training accuracy, F1 Score, and Cohen's kappa are utilized for comprehensive evaluation.","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141744454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development a nomogram prognostic model for survival in heart failure patients based on the HF-ACTION data. 基于 HF-ACTION 数据,建立心力衰竭患者生存预后提名图模型。
IF 3.3 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-19 DOI: 10.1186/s12911-024-02593-1
Ting Cheng, Dongdong Yu, Jun Tan, Shaojun Liao, Li Zhou, Wenwei OuYang, Zehuai Wen
{"title":"Development a nomogram prognostic model for survival in heart failure patients based on the HF-ACTION data.","authors":"Ting Cheng, Dongdong Yu, Jun Tan, Shaojun Liao, Li Zhou, Wenwei OuYang, Zehuai Wen","doi":"10.1186/s12911-024-02593-1","DOIUrl":"10.1186/s12911-024-02593-1","url":null,"abstract":"<p><strong>Background: </strong>The risk assessment for survival in heart failure (HF) remains one of the key focuses of research. This study aims to develop a simple and feasible nomogram model for survival in HF based on the Heart Failure-A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION) to support clinical decision-making.</p><p><strong>Methods: </strong>The HF patients were extracted from the HF-ACTION database and randomly divided into a training cohort and a validation cohort at a ratio of 7:3. Multivariate Cox regression was used to identify and integrate significant prognostic factors to form a nomogram, which was displayed in the form of a static nomogram. Bootstrap resampling (resampling = 1000) and cross-validation was used to internally validate the model. The prognostic performance of the model was measured by the concordance index (C-index), calibration curve, and the decision curve analysis.</p><p><strong>Results: </strong>There were 1394 patients with HF in the overall analysis. Seven prognostic factors, which included age, body mass index (BMI), sex, diastolic blood pressure (DBP), exercise duration, peak exercise oxygen consumption (peak VO<sub>2</sub>), and loop diuretic, were identified and applied to the nomogram construction based on the training cohort. The C-index of this model in the training cohort was 0.715 (95% confidence interval (CI): 0.700, 0.766) and 0.662 (95% CI: 0.646, 0.752) in the validation cohort. The area under the ROC curve (AUC) value of 365- and 730-day survival is (0.731, 0.734) and (0.640, 0.693) respectively in the training cohort and validation cohort. The calibration curve showed good consistency between nomogram-predicted survival and actual observed survival. The decision curve analysis (DCA) revealed net benefit is higher than the reference line in a narrow range of cutoff probabilities and the result of cross-validation indicates that the model performance is relatively robust.</p><p><strong>Conclusions: </strong>This study created a nomogram prognostic model for survival in HF based on a large American population, which can provide additional decision information for the risk prediction of HF.</p>","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11264587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141726917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hybridized deep learning goniometry for improved precision in Ehlers-Danlos Syndrome (EDS) evaluation. 混合深度学习动态关节角度测量法,提高埃勒斯-丹洛斯综合征(EDS)评估的精确度。
IF 3.3 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-18 DOI: 10.1186/s12911-024-02601-4
Thirumalesu Kudithi, J Balajee, R Sivakami, T R Mahesh, E Mohan, Suresh Guluwadi
{"title":"Hybridized deep learning goniometry for improved precision in Ehlers-Danlos Syndrome (EDS) evaluation.","authors":"Thirumalesu Kudithi, J Balajee, R Sivakami, T R Mahesh, E Mohan, Suresh Guluwadi","doi":"10.1186/s12911-024-02601-4","DOIUrl":"10.1186/s12911-024-02601-4","url":null,"abstract":"<p><strong>Background: </strong>Generalized Joint Hyper-mobility (GJH) can aid in the diagnosis of Ehlers-Danlos Syndrome (EDS), a complex genetic connective tissue disorder with clinical features that can mimic other disease processes. Our study focuses on developing a unique image-based goniometry system, the HybridPoseNet, which utilizes a hybrid deep learning model.</p><p><strong>Objective: </strong>The proposed model is designed to provide the most accurate joint angle measurements in EDS appraisals. Using a hybrid of CNNs and HyperLSTMs in the pose estimation module of HybridPoseNet offers superior generalization and time consistency properties, setting it apart from existing complex libraries.</p><p><strong>Methodology: </strong>HybridPoseNet integrates the spatial pattern recognition prowess of MobileNet-V2 with the sequential data processing capability of HyperLSTM units. The system captures the dynamic nature of joint motion by creating a model that learns from individual frames and the sequence of movements. The CNN module of HybridPoseNet was trained on a large and diverse data set before the fine-tuning of video data involving 50 individuals visiting the EDS clinic, focusing on joints that can hyperextend. HyperLSTMs have been incorporated in video frames to avoid any time breakage in joint angle estimation in consecutive frames. The model performance was evaluated using Spearman's coefficient correlation versus manual goniometry measurements, as well as by the human labeling of joint position, the second validation step.</p><p><strong>Outcome: </strong>Preliminary findings demonstrate HybridPoseNet achieving a remarkable correlation with manual Goniometric measurements: thumb (rho = 0.847), elbows (rho = 0.822), knees (rho = 0.839), and fifth fingers (rho = 0.896), indicating that the newest model is considerably better. The model manifested a consistent performance in all joint assessments, hence not requiring selecting a variety of pose-measuring libraries for every joint. The presentation of HybridPoseNet contributes to achieving a combined and normalized approach to reviewing the mobility of joints, which has an overall enhancement of approximately 20% in accuracy compared to the regular pose estimation libraries. This innovation is very valuable to the field of medical diagnostics of connective tissue diseases and a vast improvement to its understanding.</p>","PeriodicalId":9340,"journal":{"name":"BMC Medical Informatics and Decision Making","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11264507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141723165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early detection of cardiorespiratory complications and training monitoring using wearable ECG sensors and CNN. 利用可穿戴心电图传感器和 CNN 对心肺并发症进行早期检测和训练监控。
IF 3.3 3区 医学
BMC Medical Informatics and Decision Making Pub Date : 2024-07-16 DOI: 10.1186/s12911-024-02599-9
HongYuan Lu, XinMiao Feng, Jing Zhang
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