Annals of pulmonary and critical care medicine最新文献

{"title":"Прогнозирование исходов лечения новорожденных, требующих медицинской эвакуации по шкале TRIPS: наблюдательное когортное ретроспективное исследование","authors":"Рустам Фаридович Мухаметшин, О. П. Ковтун, Н. С. Давыдова, А. А. Курганский","doi":"10.21320/1818-474x-2023-2-130-139","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-2-130-139","url":null,"abstract":"АКТУАЛЬНОСТЬ: Объективизация оценки тяжести состояния и прогнозирование исходов остаются важными задачами на этапе предтранспортной подготовки и относятся к сложнейшим разделам деятельности транспортных бригад. Значительное разнообразие шкал и различные требования к их применению свидетельствуют об отсутствии единого мнения относительно выбора конкретного угрозометрического и прогностического инструмента. ЦЕЛЬ ИССЛЕДОВАНИЯ: Изучить исходы лечения новорожденных, перенесших межгоспитальную транспортировку, в зависимости от оценки по шкале TRIPS (Transport Risk Index of Physiologic Stability for Newborn Infants). МАТЕРИАЛЫ И МЕТОДЫ: Наблюдательное когортное ретроспективное исследование включает данные 604 выездов транспортной бригады к новорожденным детям, находившимся на дистанционном наблюдении реанимационно-консультативного центра в период с 1 августа 2017 г. по 31 декабря 2018 г. Выполнено разделение общей выборки на группы в зависимости от оценки по исследуемой шкале с последующим сравнением объема и параметров интенсивной терапии и исходов в данных группах. РЕЗУЛЬТАТЫ: При разделении исследуемой выборки на группы в соответствии с оценкой по шкале TRIPS наблюдается достоверное различие по массе при рождении и гестационному возрасту. Увеличение оценки по шкале TRIPS среди эвакуированных новорожденных ассоциировано с увеличением риска смерти с максимальным относительным риском 21,4 (3,35–136,72) (между группами 6 и 1). По прочим исходам наблюдаются достоверные различия между группами с минимальными и максимальными значениями оценки по TRIPS. ВЫВОДЫ: Шкала TRIPS позволяет стратифицировать новорожденных, требующих межгоспитальной транспортировки, по риску развития летального исхода и осложнений предстоящего госпитального этапа.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75238978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intellectual ventilation modes in Russian Federation: a short questionnaire survey","authors":"R. D. Komnov, A. A. Eremenko","doi":"10.21320/1818-474x-2023-1-83-90","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-83-90","url":null,"abstract":"INTRODUCTION: There are a lot of clinical trials about benefits of closed-loop ventilation modes, which are able to automatically adjust certain respiratory settings. These studies describe safety, reliability and advantages of intellectual modes over conventional ventilation modes. OBJECTIVE: To assess awareness of Russian intensive care practitioners about closed loop ventilation modes and availability of these modes in routine practice. The second aim was to explore difficulties and problems that arise for practitioners during work with these modes. MATERIALS AND METHODS: A short survey conducted with online and offline questionnaire. The survey consisted of nine questions regarding the application of closed-loop modes, some question has open answers. RESULTS: The response rate of the survey was 33 % (248 of 750). Most of respondents (85 %) have heard about closed-loop modes, and 52 % had access to these technologies in routine practice. But only 23 % of respondents use Adaptive Support Ventilation (ASV) and analogues as primary mode in their routine practice, 9 % point to Intellivent-ASV®, less than 1 % point to PAV + TM (Proportional Assist Ventilation) and nobody point to NAVA (Neurally Adjusted Ventilatory Assist) and Smart Care®. Over half of respondents (62 %) from clinicians who have access to this technology pointed to the lack of knowledge about closed loop modes; 60 % pointed to insufficient education and 40 % pointed to the lack of equipment. These facts demonstrate the necessity of additional educational programs for implementation of modern technologies in practice, need for organization of post customer service for respirators and provision of consumables in some hospitals. CONCLUSIONS: this questionnaire showed that 85 % of practitioners have heard about closed-loop ventilation modes, and half of them had access to these technologies in routine practice, but just 30 % regularly use one of these technologies.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72732898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on the article of R. Iu. Ovsiannikov and K. M. Lebedinskii “Correlation between changes in arterial blood oxygen partial pressure, oxygen uptake and carbon dioxide elimination by the lungs with changes in positive end expiratory pressure: a prospe","authors":"A. Yaroshetskiy","doi":"10.21320/1818-474x-2023-1-145-148","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-145-148","url":null,"abstract":"Comment on the article of R.Iu. Ovsiannikov and K.M. Lebedinskii “Correlation between changes in arterial blood oxygen partial pressure, oxygen uptake and carbon dioxide elimination by the lungs with changes in positive end expiratory pressure: a prospective observational study”","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88837203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in the pituitary — thyroid system during extracorporeal membrane oxygenation: a prospective observational study","authors":"N. Altshuler, M. Kutcyi, K. Gubarev, G. I. Bagzhanov, K. Popugaev","doi":"10.21320/1818-474x-2023-1-43-55","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-43-55","url":null,"abstract":"INTRODUCTION: The severity of the patient's condition that required ECMO and the changes observed in the pituitary — thyroid system (decreased T4 and T3 levels, low-normal or decreased TSH level) can be considered as a lack of body reserves due to the developed critical illness. OBJECTIVES: Study changes of TSH, T3, T4 levels during the ECMO procedure, during weaning/death on the ECMO. MATERIALS AND METHODS: The prospective observational study was performed in intensive care unit (47 patients on ECMO). After connecting ECMO (D0), (D1-D3-D5-D7-D9), and until the completion of ECMO, assessment of TSH, FT4, FT3 levels was carried out. OBJECTIVE: Analysis of changes in thyroid hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3) levels in blood plasma during ECMO, at ECMO weaning/death on ECMO. RESULTS: On the day of ECMO (D 0) and every second day, median FT4 levels were D0 (p = 0.03); D1 (p = 0.03); D3 (p = 0.05), D11 (p = 0.02) and last observation day (p = 0.009) between surviving and dying patients respectively. T3 level D5 (3.1–1.9; p = 0.002); D11 (3.7–2.5; p = 0.05), last day of follow-up (3.1–2; p = 0.001), respectively. On the last day of ECMO between the survived and non-survived patients there were the following: differences in TSH levels; negative correlation of lactate levels, SOFA score and FT3, TSH, FT4. The analysis of the ROC curve (low levels of FT3, FT4, TSH in plasma in patients on the last day of ECMO) indicates a prognostically unfavorable outcome. CONCLUSIONS: The moment of ECMO connection initiation is regarded as subacute phase critical illness. Along with a high level of plasma lactate and high score of SOFA scale, the level of decrease in FT3, FT4 and TSH in patients correlates with the lethal outcome. Low levels of TSH, FT4, and FT3 may be considered as a predictor of adverse outcome at the time of weaning/death on ECMO.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84049232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative transfusion is a risk factor for cerebral injury after cardiac surgery in children: a prospective observational study","authors":"A. Ivkin, E. Grigoryev, D. G. B. D. G. Balakhnin, I. I. Chermnykh","doi":"10.21320/1818-474x-2023-1-101-114","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-101-114","url":null,"abstract":"INTRODUCTION: Donor blood components are able to initiate a systemic inflammatory response syndrome (SIRS) and potentiate neuroinflammation with subsequent cerebral damage. OBJECTIVE: To study the effect of transfusion on the development of cerebral damage during the surgical correction of congenital heart defects in children. MATERIALS AND METHODS: 78 patients aged from 1 to 78 months, weighing from 3.3 to 21.5 kg, were studied. All patients underwent correction of a septal defect under cardiopulmonary bypass. All patients were divided to group 1 — without the use of transfusion and group 2 — with the use of red blood cell transfusion. Cerebral damage markers (S-100-β protein, neuron-specific enolase (NSE) and glial fibrillar acidic protein (GFAP)) and SIRS (interleukins 1 (ILb-1), 6 (IL-6), 10 (IL-10) and tumor necrosis factor alpha (TNF-α) were studied. Markers ware studied at three control points: 1 — before the start of surgery, 2 — immediately after end of cardiopulmonary bypass, 3 — 16 hours after the end of the operation. RESULTS: The peak concentration of most markers in the blood in both groups of patients was noted at the 2nd control point. The concentration of all markers of cerebral damage was significantly higher in the transfusion group at the 2nd control point: S-100-β protein (ng/ml) — 509.90 [379.30–871.70] and 717.10 [517.90–1195.33] (р = 0.024); NSE (ng/ml) — 17.55 [11.19–26.41] and 34.05 [17.06–44.90] (р = 0,023); GFAP (ng/ml) — 0.1190 [0.1135–0.1245] and 0.1231 [0.1138–0.1493]. Correlations were found between markers of cerebral damage and SIRS, the strongest of which was the relationship between NSE and TNF-α at the 3rd control point — Rho = 0.43 (p = 0.0001). A correlation of S-100-β protein with transfusion volume was observed at the 2nd (Rho = 0.48, p = 0.00065) and 3rd control points (Rho = 0.36, p = 0.01330). CONCLUSIONS: The influence of the fact of transfusion and the dose of red blood cell on the development of cerebral damage during cardiac surgery in children has been proven.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85190998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhospital transport of critically ill adult patients: guidelines of the All-Russian public organization “Federation of Anesthesiologists and Reanimatologists”","authors":"E. Grigoryev, I. V. Bratishchev, A. Levit, A. Shchegolev, V. V. Shustrov","doi":"10.21320/1818-474x-2023-1-7-13","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-7-13","url":null,"abstract":"Intrahospital transportation of critical patients is a frequent procedure in the practice of most medical organizations, which in some cases is accompanied by a number of adverse events up to the occurrence of critical incidents. In order to improve patient safety, the Federation of Anesthesiologists and Reanimatologists of Russia (FAR) initiated in 2022 the development of national guidelines for the intrahospital transportation of critically ill adult patients. The literature search was focused on meta-analyses and randomized controlled trials, but also included registries, non-randomized comparative and descriptive studies, case series, cohort studies, systematic reviews, and expert opinion. Before publication, the guidelines were approved by the Presidium of the Board of the FAR. The guidelines are focused on the peculiarities of the organization of the process of intrahospital transportation, critical indicators of vital functions and their monitoring using methods for an objective assessment of the condition of patients. Special attention is paid to the need to form a specialized team and its training. For each recommendation, the level of evidence is presented. The guidelines were developed by experts in the field of anesthesiology and intensive care for anesthesiologists-reanimatologists and must be used as an evidence-based basis for making a decision to transport a particular critical patient by responsible health professional.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86255561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to treatment in intensive care units on the example of pediatric sepsis: a review","authors":"P. Mironov, Yu. S. Аleksandrovich, K. V. Pshenisnov, R. Akhmetshin, V. Potapov","doi":"10.21320/1818-474x-2023-1-123-132","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-123-132","url":null,"abstract":"INTRODUCTION: Intensive care does not always require only a large amount of resources. An important aspect is the formation of a multidisciplinary team involved in the treatment of patients in critical condition. OBJECTIVE: To demonstrate the need for the staff of intensive care units to use protocols for the diagnosis and treatment of critical conditions on the example of sepsis in children. MATERIALS AND METHODS: The analysis of publications devoted to the study of the impact of the implementation of the clinical recommendations of the Surviving Sepsis Campaign for the treatment of sepsis in children on the outcomes of the disease. The articles were searched in the abstract databases PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science Core Collection and Google Scholar for the period from 2011 to July 2022. Keywords were used: “pediatric sepsis”, “implementation”, “protocolized treatment”, “adherence”. RESULTS: During the search, only thirteen observational studies were found, nine of which were presented retrospectively, which can be attributed to the design flaws of the submitted works. It was revealed that the use of the entire complex of diagnostic and therapeutic measures presented in clinical recommendations and protocols for intensive therapy of sepsis in children can significantly improve the results of treatment, but the commitment of doctors to their use in routine clinical practice remains low and does not exceed 40 %. CONCLUSIONS: The main reason for the lack of commitment to the implementation of recommendations and standards for the treatment of sepsis in children is not only in the presence of organizational obstacles, but also in the absence of reasonable algorithms for its implementation.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"95 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83405626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mathematical modeling of severe ischemic stroke with multiple organ failure: a retrospective observational study","authors":"V. Silkin, V. I. Ershov, V. Burdakov, T. Biryukova, A. Bredikhin, T. Y. L. T. Yu. Lozinskaya","doi":"10.21320/1818-474x-2023-1-91-100","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-91-100","url":null,"abstract":"INTRODUCTION: The development of organ dysfunctions and multiple organ failure (MOF) in patients with severe ischemic stroke (IS) is a factor in aggravating the clinical course and outcome. OBJECTIVE: To study the prognostic aspects of the clinical course and outcomes of severe IS with the development of MOF. MATERIALS AND METHODS: The study included 110 patients with severe IS (National Institutes of Health Stroke Scale ≥ 16 points). To assess the severity of MOF on days 1 and 5 of hospitalization, standard scales SAPS II, SOFA were used. The predictor significance of the indicators was determined by a comparative regression analysis using the least squares method. RESULTS: In patients with a fatal outcome compared to survivors, a higher severity of MOF on the SAPS II was observed both on the first (31 (25; 39) and 24 (21; 29) respectively, p < 0.0001) and fifth days of the disease (40 (33; 49.5) and 29 (25; 35) respectively, p < 0.0001). In the development of severe IS with MOF, an unfavorable outcome is significantly more often observed in the cardioembolic subtype compared to the atherothrombotic subtype of IS (50.75 and 29.85 % respectively, p = 0.0469). The probable mortality according to comparative regression analysis was significantly higher in cardioembolic stroke for patients with MOF severity from 29 to 49 points on the SAPS II (p = 0.0021). CONCLUSIONS: MOF is the most important predictor of death in severe IS. At the same time, the cardioembolic subtype of IS differ by a higher probable mortality in comparison with the atherothrombotic subtype with the MOF severity in the range of 29–49 points according to the SAPS II scale.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79347224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current trends in the diagnosis and treatment of acute tumor lysis syndrome in children: a review","authors":"N. Matinyan, T. Valiev, L. Martynov, V. Akimov, E. A. Kovaleva, Yuri V. Buidenok","doi":"10.21320/1818-474x-2023-1-115-122","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-115-122","url":null,"abstract":"INTRODUCTION: Acute tumor lysis syndrome (ATLS) complicates the treatment of highly aggressive leukemia, lymphomas in children and is accompanied by a fatal outcome in 21.4 % of patients. The basis of ATLS is the decay of tumor cells, in which the volume of decay products exceeds the excretory capabilities of the kidneys. The ATLS risk group includes patients with acute lymphoblastic leukemia accompanied by hyperleukocytosis (above 100×109/L) and non-Hodgkin's lymphomas with a large tumor mass (III–IV stages of the disease). To date, the volume of thematic publications in the aggregator of the PubMed medical database is not so large: over the past 10 years, there have been 12 articles, which makes the task of systematizing previously accumulated and recently received information even more relevant for the practitioner. OBJECTIVE: Generalization of the modern scientific base for the diagnosis and treatment of ATLS in children. MATERIALS AND METHODS: To highlight the modern scientific base concerning the diagnosis and treatment of ATLS in children with oncohematological diseases, a search was conducted in PubMed, Research Gate, Web of Science Core Collection and Google Scholar systems for the period from 2000 to August 2022. RESULTS: In total, 94 articles were found, including 1 systematic review with meta-analysis and 16 review articles that meet the requirements. CONCLUSIONS: Conservative ATLS prophylaxis is effective in 93.4–93.6 % of patients. However, in 8.8–21.4 % of patients, ATLS acquires a rapid character, accompanied by the lack of the ability to conservatively correct the indicators of potassium, phosphorus, uric acid. Additional study of the pathogenetic mechanisms of the complication, identification of key targets of drug therapy and a multidisciplinary approach in the treatment of an extremely prognostically unfavorable group of oncohematological patients with advanced stages of the tumor process are possible components of further improving the effectiveness of ATLS therapy.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"142 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88963834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protein-energy metabolism and nutritional support in patients on extracorporeal membrane oxygenation: a systematic review","authors":"N. Z. Kanshaov, I. Leyderman, A. O. Marichev","doi":"10.21320/1818-474x-2023-1-56-70","DOIUrl":"https://doi.org/10.21320/1818-474x-2023-1-56-70","url":null,"abstract":"INTRODUCTION: Patients on extracorporeal membrane oxygenation (ECMO) are among the most severe in the intensive care unit (ICU), they require complex treatment, accompanied by a long stay in the hospital and rehabilitation. Nutritional support (NS) plays an important role in the intensive care program. Despite an increase in the use of ECMO in the ICU over the past decade, informative clinical data regarding the optimal methods of maintaining nutritional status and controlling metabolism are rare. The lack of evidence base and guidelines for NS for adult patients on ECMO results in heterogeneity in clinical practice regarding optimal macro and micronutrient requirements, time of NS initiation, type and amount of nutritional support solutions. OBJECTIVE: Provide a review and critical assessment of the latest data regarding NS in critically ill adult patients on ECMO. MATERIALS AND METHODS: A systematic search and selection of publications was performed using the PubMed database. Studies published from 2012 to 2021 were analyzed to explore the approaches to NS in ECMO patients. Relevant studies were limited to randomized controlled trials, observational studies and clinical trials. RESULTS: A total of 14 observational studies were selected. Early enteral nutrition has been considered safe and feasible for ECMO patients, but achieving energy and protein targets is challenging. Data on the impact of NS on clinical outcomes and complications have been conflicting. Efforts should be made to achieve an adequate patient supply on ECMO of more than 80 % of the calculated energy and protein targets. NS in ECMO patients should be carried out in accordance with current guidelines for NS in critically ill patients until further data become available. CONCLUSIONS: A personalized approach is important principle of nutritional and metabolic therapy. Further studies are needed to investigate the association of various NS methods on clinical outcome endpoints in ICU ECMO patients.","PeriodicalId":93261,"journal":{"name":"Annals of pulmonary and critical care medicine","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87654229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}