{"title":"Profile of Cerebral Palsy Patients in Dr. Soetomo General Hospital Surabaya, Indonesia","authors":"Qorina Nadya Salfi, D. Saharso, Atika Atika","doi":"10.20473/BHSJ.V2I1.12803","DOIUrl":"https://doi.org/10.20473/BHSJ.V2I1.12803","url":null,"abstract":"Introduction: Limited profile data of Cerebral Palsy (CP) patients in Indonesia leads CP to be a less-known disease. The aim of this study is to describe CP patient’s characteristics, including demographic aspect, gestation and birth history, and CP related condition in Dr. Soetomo General Hospital Surabaya, Indonesia.Methods: Cross-sectional study using medical records of CP patients in Dr. Soetomo General Hospital (Surabaya, Indonesia) Outpatient Installation for Pediatric Neurology from January 2016 to June 2018. Data processed descriptively.Results: From total 107 patients, 50 subjects met inclusion criteria. Mean age was 6.16 years old, with domination of male (3:2), live in Surabaya (56%), malnourished (24%), normal birth weight (80.9%), term age of birth (66.7%), spontaneous labor (60%), and also prenatal events as causes of Cerebral Palsy (69.5%). Pneumonia was found to be most among postnatal events leading to Cerebral Palsy (30%). Most of the type was spastic (9:1) with quadriplegic as the dominating one (64%). Congenital malformation was rarely found (38%), but co-morbidities were found in almost all sample (92%).Conclusion: Gestation and birth history of CP patients are mostly ranged normal. Prenatal etiology is found dominating as the cause of CP, therefore emendation in antenatal care (ANC) shall be considered. Analytical study about CP in Indonesia also must be improved because it is still hardly found.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86021988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Risk Factors for Urinary Tract Infection in Hospitalized Patients","authors":"H. Setyorini, N. Mardiana, Artaria Tjempakasari","doi":"10.20473/BHSJ.V2I1.11549","DOIUrl":"https://doi.org/10.20473/BHSJ.V2I1.11549","url":null,"abstract":"Introduction: Urinary tract infection (UTI) is the most common infection that can be fatal and has higher rate mortality especially in some patient. This study is aim to analyze risk factors for urinary tract infection in hospitalized patients for prevention and more aggressive approach can be taken.Methods: Consecutively, medical records of 285 patients with urinary analysis was recorded for risk factors and urine culture results if suspected UTI. Risk factors for sex, age, urinary catheter, urolithiasis, DM, and immobilization was analyzed with bivariate analysis and multivariate analysis.Results: From 285 patients, 92 patients had UTI with average age was 52.45 years old, 48 (56.49%) were female. Most common pathogen were E. coli (41.3%), Enterobacter sp. (8.8%) and Enterococcus faecalis (7.6 %). From bivariate analysis, geriatric age (>60 years) has RR 1.421 (95% CI 1.015-1.989, p=0.046) and immobilization has RR 1.861 (95% CI 1.266-2.738, p=0.007), whereas sex (RR 1.190 95% CI 0.851 – 1.664, p=0.310), diabetes (RR 1.171 95% CI 0.833 – 1.645, p=0.367), insulin usage (RR 0.900 95% CI 0.519 – 1.561, p= 0.703), glycosuria (RR 1.152 95% CI 0.741 – 1.791, p=0.522), and CKD (RR 1.475 95% CI 0.896 – 2.430, p= 0.126) give insignificant result. From multivariate analysis, urinary catheter has OR 4.506 (95% CI 2.312-8.872, p=0.000), urolithiasis with OR 4.970 (95% CI 1.931-12.787, p=0.001), and hyperglycemia has OR 2.871 (95% CI 1.485-5.551, p=0.002).Conclusion: Geriatric age and immobilization are risk factors for urinary tract infection, and urinary catheter, urolithiasis, and hyperglycemia are independent risk factors for urinary tract infection.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90805717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Winni Aprillia Putri, Abu Rohiman, S. Sulistiawati, Dwiyanti Puspitasari
{"title":"Effects of Climatic Factors on The Incidence Rate of Dengue Virus Infection in Surabaya During 2010-2013","authors":"Winni Aprillia Putri, Abu Rohiman, S. Sulistiawati, Dwiyanti Puspitasari","doi":"10.20473/BHSJ.V2I1.9340","DOIUrl":"https://doi.org/10.20473/BHSJ.V2I1.9340","url":null,"abstract":"Introduction: Dengue Virus Infection (DVI) is one of cautious mosquito-borne virus disease that transmitted by Aedes aegypti and Aedes albopictus. Surabaya has the highest incidence rate of DVI in East Java. Transmission of dengue virus were significantly affected by the change of climatic factor components (precipitation, temperature, and humidity). This study is aimed to analyze the correlation between climatic factor components with the incidence rate of DVI in Surabaya and its distribution.Methods: This is a cross-sectional study using analytic observational approach. The Incidence rate of DVI during 2010-2013 datas were taken from Surabaya Health Office. Climatic factor datas on the same years were taken from Juanda Meteorological Station. Correlation tests were performed by using Spearman Test.Results: As the result, there were 7,685 DVI patients during 2010-2013. Male patients have less proportion (51.89%). The highest DVI cases are from the age group of 5-14 years (>40%). Incidence rate of DVI was increased during February to April, and highest incidence rate occured in 2010 (n=3,379). There were significant correlation between precipitation (r=0.419, p-value p=0.003) and humidity (r=0.502, p-value=0.000) with the incidence rate of DVI in Surabaya during 2010-2013.Conclusion: Therefore, precipitation and humidity are two climatic factor components that may effect the incidence rate of DVI in Surabaya.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"143 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86183260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CHOP and R-CHOP Therapeutic Responses in Non-Hodgkin Lymphoma Patients in Dr. Soetomo General Hospital Surabaya","authors":"Rina Syarifah Salma, M. Sedana, S. Yudho","doi":"10.20473/BHSJ.V1I2.9244","DOIUrl":"https://doi.org/10.20473/BHSJ.V1I2.9244","url":null,"abstract":"Introduction: Non-Hodgkin Lymphoma (NHL) is a group of lymphoid-derived malignant disease with heterogenic biological and clinical manifestations. For over 30 years, CHOP (Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) has been the first choice of chemotherapy for aggressive NHL. Later in 1997 Rituximab as anti-CD20 monoclonal antibody was introduced and then combined with CHOP as R-CHOP. The objective of this study is to acknowledge the response of the CHOP and R-CHOP therapy in Non-Hodgkin Lymphoma patients at Dr. Soetomo General Hospital.Methods: The design of this study was retrospective observational study using secondary data obtained from patient’s medical records from 2011 to 2015. The data selected from the medical records are the result of the therapy, as well as patient’s gender and age. Results: The results of patients’ therapy were classified into four categories: The study showed that 51.28% patients had Complete Response, followed by Partial Response (28.21%), Progressive Disease (17.95%), and No Change (2.56%). Sample characteristics showed male patients in higher percentage (66.67%), and the majority of patients’ age between 51-60 years old (30.77%). The use of CHOP and R-CHOP regiment were 76.92% and 20,52% respectively.Conclusion: Most of the patients had a complete response. The CHOP regiment is more commonly used in patients compared to R-CHOP.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73557206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nur Annisa Nugraheningtyasari, Ninik Asmaningsih Soemayarso, D. Susanti
{"title":"Correlation Between Nutritional Status Of Children Aged 12 – 36 Months And Mother’s Working Status In Taman, Sidoarjo","authors":"Nur Annisa Nugraheningtyasari, Ninik Asmaningsih Soemayarso, D. Susanti","doi":"10.20473/BHSJ.V1I2.9266","DOIUrl":"https://doi.org/10.20473/BHSJ.V1I2.9266","url":null,"abstract":"Introduction: The correlation between child’s nutritional status and mother’s working status in Indonesia is still unclear. Some research report a high prevalence of low-nourished children whose mother is working, while others report a non significant correlation between child’s nutritional status and mother’s working status.Methods: This study was case-control study, sample of low-nourished children (treatment group) & well-nourished children (control) are taken from 21 Posyandu in Taman, Sidoarjo in 2015. All data were analyzed using Chi Square test.Results: There are 72 samples which are suitable with the inclusion criteria, consisted of 36 low-nourished children and 36 well-nourished children. From 72 samples, 28 children have a working mother and 44 children have a non working mother. There were no correlation between Mother’s working status (p=0,486), Number of children in the family (p=0,468), History of chronic disease (p=0,054) with child’s nutritional status. Level of family income, Mother’s education level, History of exclusive breastfeeding, Energy consumption level, Protein consumption level were correlated with child’s nutritional status with value (p=0,000), (p=0,002), (p=0,002), (p=0,000), (p=0,001) respectively.Conclusion: Mother’s working status is proved that is not correlated with child’s nutritional status. But, level of family income, mother’s education level, energy & protein consumption level, and history of exclusive breastfeeding are significantly correlated with child’s nutritional status.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74783049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Antioxidant Vitamin C and E Administration on Spermatozoa Quality of White Rat (Rattus Norvegicus) Strain Wistar Male Against Allethrin Exposure","authors":"Faisal Yusuf Ashari, R. Yudiwati, R. H. Aswin","doi":"10.20473/BHSJ.V1I2.9282","DOIUrl":"https://doi.org/10.20473/BHSJ.V1I2.9282","url":null,"abstract":"Introduction: Allethrin is an active ingredient used in anti-mosquito drugs. Allethrin enters the body through inhalation, allegedly can disrupt the quality of spermatozoa by decreasing its amount, motility, viability and morphology. Many studies suggested that with sufficient intake of vitamin C and E would be able to minimize free radicals caused by allethrin. This study aims to investigate the effect of giving antioxidant vitamin C and E on spermatozoa quality of white rat (Rattus norvegicus) strain Wistar male with allethrin exposure.Methods: This research was a post-test design randomized control group design using Rattus novergicus male strains Wistar exposed to allethrin (LPB IPB veterinary stem cell). A total of 16 white rat strains Wistar male divided into 4 groups, one control group (without any treatment) and 3 treatment groups (given antioxidant vitamin C, vitamin E and both). The exposure of mosquito coils was performed 8 hours per day for 45 days and on the 46th day, spermatozoa was observed. The data were analyzed using ANOVA one way and BNT.Results: The results showed that treatment with vitamins affected the amount, motility and viability of rat spermatozoa exposed to allethrin. The mean amount of control group spermatozoa and treatment was 14,93, the mean spermatozoa motility control and treatment groups were 45,13 and the mean spermatozoa viability of control and treatment groups was 58,88. This is shown by the real difference between the control group and the treatment (p <0,05). Similarly, in the control group found morphological abnormalities.Conclusion: Exposure of mosquito coils 8 hours/day for 45 days decreased the spermatozoa quality. Overall, the admission of antioxidant vitamin C and E are able to maintain the quality of spermatozoa instead of one type of vitamin.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85689945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation Between Nutritional Status of Pregnant Women Based on Upper Arm Circumference and Preeclampsia/Eclampsia Severity Degree at Jagir Public Health Center During January 2014 - March 2014","authors":"Dian Aprilia, B. Prasetyo, S. Sulistiawati","doi":"10.20473/BHSJ.V1I2.9533","DOIUrl":"https://doi.org/10.20473/BHSJ.V1I2.9533","url":null,"abstract":"Introduction: Preeclampsia/eclampsia is one of the causes of maternal mortality besides bleeding and infection. The exact etiology of this condition is still unknown. Nutritional status of pregnant women who are overweight can increase the risk. This study aims to determine the correlation between obesity and the severity of preeclampsia/eclampsia through upper arm circumference (UAC) measurement.Methods: This study is a cross-sectional analytic study. Data on preeclampsia/eclampsia and UAC obtained from patient medical records in Jagir Public Health Center Surabaya. Data were analyzed using Chi-square test.Results: Prevalence of mild preeclampsia was greater than severe preeclampsia (87.5% and 12.5%). The majority of patients with mild preeclampsia have normal UAC size (91.3%). Severe preeclampsia found higher in obesity group than normal nutritional status group (22.2% and 9.1%). From Chi-square test analysis, found that p = 0.557.Conclusion: There was no significant correlation between the nutritional status of pregnant women based on UAC measurement of and the severity of preeclampsia/eclampsia.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90098682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Profile of Acute Pharyngitis at Dr. Soetomo General Hospital Pediatric Outpatients Clinic in 2013","authors":"Amanda Trilana, D. Susanti, Satrio Boediman","doi":"10.20473/BHSJ.V1I2.9495","DOIUrl":"https://doi.org/10.20473/BHSJ.V1I2.9495","url":null,"abstract":"Introduction: Acute Pharyngitis remains a common health problem in the world, especially in developing countries andmostly infects children. Around 6,2 to 9,7 million children worldwide went to clinics and emergency department with pharyngitis. This study aims to find the characteristic of acute pharyngitis in childen at Dr. Soetomo Hospital Surabaya.Methods: This study was a cross sectional, using medical records of acute pharyngitis patients in pediatric outpatient clinic. Data collected based on age, sex, chief complaint, additional complaints and clinical signs.Results: Total samples were 92 patients with sex proportion of 48 males (52,2%) and 44 females (47,8%). Based on age, mostly at 0 – 3 years old (68,4%). The most common chief complains were fever, followed by cough and sore throat for 55,4%, 28,2% and 16,4% respectively. Based on additional complain, 56,5% still has good appetite. Based on clinical signs, hyperemic pharyngeal was 91,3% and lymph nodes enlargement was 8,7%.Conclusion: Acute pharyngitis mostly infected toddler characterized with fever, and hyperemic pharyngeal as a clinical sign.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"280 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76255310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacteria Pattern, Results of Antibiotic Sensitivity Test, and Complications of Deep Neck Abscess Patients in Dr. Soetomo General Hospital","authors":"Syaiful Rijal, A. Romdhoni","doi":"10.20473/BHSJ.V1I2.9832","DOIUrl":"https://doi.org/10.20473/BHSJ.V1I2.9832","url":null,"abstract":"Introduction: Deep Neck Abscess is the accumulation of pus inside the potential space between the deep neck fasciae. The incidence has decreased dramatically since the antibiotic era. Empirical antibiotics are administered before the sensitivity test results out, so it is important to know the map of bacteria and its resistance.Methods: This study was conducted retrospectively using medical records of patients with deep neck abscess in Dr. Soetomo General Hospital Surabaya during January 2014-December 2017. Data recorded included gender, age, location, results of bacteria culture examination, antibiotic sensitivity test, and complications that occurred. Data is processed descriptively. Results: Of the 162 patients, 102 (62.96%) were males, followed by 60 females (37.04%). The 46-60 years old group has the largest percentage (33.95%). Whereas the most common location of abscess was in the submandibular (42.59%). Pus culture test, most bacteria is Klebsiella pneumonia (13.04%). While the sensitivity test shows that meropenem has the highest sensitivity number (73.58). Most complications were sepsis, in 48 patients (29.63%). Conclusion: Klebsiella pneumonia, Staphylococcus aureus, and Streptococcus anginosus are the most common etiologies in deep neck abscess. Meropenem, cefoperazone-sulbactam, and oxacillin are the most sensitive antibiotics.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84808612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Pulmonary Lymphoma with Superior Vena Cava Syndrome","authors":"A. Rosyid, Resti Yudhawati Meliana","doi":"10.20473/BHSJ.V1I2.9858","DOIUrl":"https://doi.org/10.20473/BHSJ.V1I2.9858","url":null,"abstract":"Primary Pulmonary Lymphoma (PPL) is a clonal proliferation of lymphoid cells that involve one or two lungs (parenchyma and or bronchi. PPL is found in approximately 0.4% of all lymphoma cases and 3.6% of NHL cases. Five years survival rate at stage I and II is 90%, and 80% in stage III and IV. A 63-year-old male farmer presented with chief complaint of shortness of breath for one week before admission and preceded by coughing for a month, loss of appetite and night sweating. There was an abnormal physical examination on the right side of the chest with non-tender lymph node enlargements in the right supraclavicular and neck region and superior vena cava syndrome. CT guided FNAB suggesting NHL. Patient was treated with CHOP chemotherapy regiment. However, with high grade lymphoma, patient did not respond well.","PeriodicalId":9324,"journal":{"name":"Biomolecular and Health Science Journal","volume":"72 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88235752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}