{"title":"Neural tube defects and maternal characteristics in a North Indian Province","authors":"Y. Kadian, Roopa Malik, Nirmala Duhan, K. Rattan","doi":"10.4103/2384-5589.209484","DOIUrl":"https://doi.org/10.4103/2384-5589.209484","url":null,"abstract":"Background: Neural tube defects (NTD) affect fewer than 2 per 1000 pregnancies, account for a major burden on healthcare globally and have wide geographic prevalence. The present study was carried out with the aim to evaluate the maternal characteristics in cases of babies born with various neural tube defects in a tertiary care centre in Northern India. Methods: This retrospective analytical study was carried out by accessing and analyzing the medical case records of women who delivered babies with neural tube defects between January 2005 to December 2008 in the Department of Obstetrics and Gynaecology at Pt B D Sharma Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India. Results: Sixty seven babies had neural tube defects thus accounting for a NTD prevalence of 2.62/1000 births. Among these, there were 48 cases of anencephaly, 15 cases of meningocele and/or meningomyelocele, 4 cases of spina bifida occulta. Anencephaly was most prevalent in primiparous women of low literacy aged between 21–25 years. Similar trends were visible in meningomyelocele and spina bifida groups. Most women in the study were homemakers with almost equitable distribution in rural and urban areas. No preponderance of any particular blood group was evident for any of the neural tube defects. Conclusion: Neural tube defects affect a substantial number of newborns in India. Lower age and parity, low literary and rural residence are some of the maternal factors associated with increased risk of these disorders. Preventive strategies like periconceptional folic acid supplementation and health education may help reduce the incidence of these conditions even in low resource settings.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"28 1","pages":"25 - 29"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83957208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case report of significant congenital depressed skull fracture after cesarean section delivery","authors":"Alemayehu Mekonnen Gezmu, L. Mazhani","doi":"10.4103/ajmhs.ajmhs_28_17","DOIUrl":"https://doi.org/10.4103/ajmhs.ajmhs_28_17","url":null,"abstract":"We report a case of depressed skull fracture in an hour old newborn delivered by cesarean section for breech presentation. The depression was surgically corrected as a spontaneous resolution did not occur after some interval. Surgical correction of depressed skull fracture may be indicated depending on the depth of depression and thickness of the bone at involved part of the skull.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"1 1","pages":"123 - 125"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74424626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Adejumo, A. Akinbodewa, A. Ogunleye, O. Agoi, O. Abolarin
{"title":"A case report of acute kidney injury following the use of herbal vaginal pessary","authors":"O. Adejumo, A. Akinbodewa, A. Ogunleye, O. Agoi, O. Abolarin","doi":"10.4103/2384-5589.209485","DOIUrl":"https://doi.org/10.4103/2384-5589.209485","url":null,"abstract":"The demand and use of complementary and alternative medicine (CAM) is on the increase in many countries. Majority of the population using these herbal medicines are ignorant of their potential toxicities. We present an uncommon case of a 22 year old female who developed oliguric AKI following the use of herbal vaginal pessary. She was managed with haemodialysis and had complete renal recovery. This case highlights the potential nephrotoxicity of some herbal medication even when used locally and the urgent need to regulate CAM practice.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"1074 1","pages":"65 - 67"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73265927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Agarwal, S. Katiyar, M. Sagar, Anushree Rai, B. Gupta, M. Goel
{"title":"Incidental gravid adult filarial worm in the spermatic cord and the axillary tissue: Report of two cases","authors":"P. Agarwal, S. Katiyar, M. Sagar, Anushree Rai, B. Gupta, M. Goel","doi":"10.4103/ajmhs.ajmhs_1_17","DOIUrl":"https://doi.org/10.4103/ajmhs.ajmhs_1_17","url":null,"abstract":"Gravid adult female worm of Wuchereria bancrofti was seen in the histology sections of axillary dissection of a radical mastectomy specimen in a patient with infiltrating ductal carcinoma and in sections from spermatic cord lesion in a 4-year-old boy. Careful observation and recognition of histologic features are important for the diagnosis in hematoxylin and eosin stained sections. In the present report, we highlight the salient morphologic features of the adult worm.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"4 1","pages":"72 - 74"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87360769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Nwokocha, I. Arodiwe, K. Adiele, F. Ujunwa, J. Chinawa, I. Ogbonna, E. Obidike
{"title":"Marfan syndrome: A case report","authors":"A. Nwokocha, I. Arodiwe, K. Adiele, F. Ujunwa, J. Chinawa, I. Ogbonna, E. Obidike","doi":"10.4103/2384-5589.197969","DOIUrl":"https://doi.org/10.4103/2384-5589.197969","url":null,"abstract":"Marfan syndrome (MS) is a disorder of the connective tissues characterized by various phenotypical and genetic manifestations. We present this case to show its rarity and to highlight the need of early diagnosis to avert the numerous complications that follow it. A 7-year-old male, who presented with an abnormal body physique that was noticed at age 2 months, poor vision that was noticed 5 years ago, recurrent chest pain that started 3 years ago, and recurrent easy tiredness that started 3 years ago. He developed poor vision 2 years later. Examination revealed an acutely ill-looking child with dyspnea, grade 4 apical positive surgical margins (PSM), grade 2 diastolic murmur (at the aortic area), multiple skeletal abnormalities with lens subluxation and iridodonesis. Diagnosis of MS was made and he was comanaged with ophthalmologists and orthopedic surgeons.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"61 1","pages":"107 - 109"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80906517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ku Omeje, A. Efunkoya, I. Amole, O. Osunde, Benjamin I. Akhiwu, R. Agbara
{"title":"Giant pleomorphic adenoma of major salivary glands: A review of ten cases","authors":"Ku Omeje, A. Efunkoya, I. Amole, O. Osunde, Benjamin I. Akhiwu, R. Agbara","doi":"10.4103/2384-5589.197967","DOIUrl":"https://doi.org/10.4103/2384-5589.197967","url":null,"abstract":"Background: Pleomorphic adenoma (PA) of the major salivary glands has been documented to occur in various sizes ranging from 1 cm to 10 cm in their widest diameter; however, they can assume a grotesque proportion as a consequence of uninhibited growth in cases with delayed presentation. Patients and Methods: A retrospective study of all patients with PA of the major salivary glands with sizes >10 cm in its widest dimension and seen over a 10-year period was undertaken by retrieving sociodemographic and clinical data from patients’ case files from the Oral and Maxillofacial Unit of a Nigerian Teaching Hospital. Results: Case files of ten patients (4 males and 6 females) were reviewed over the study period. The ages ranged from 14 to 61 years, mean 33.8 ± 17.97 years. Equal distribution of five cases of PA was noted in the parotid and submandibular glands, respectively. The onset of symptoms ranged from 3 to 20 years and the largest tumor was 27 cm in its largest diameter. Only one case of malignant PA was recorded. Conclusion: Prevalence of giant PA from the study was found to be 13.5%, with a greater occurrence in the female (60%) patients compared to the male (40%) patients and with an equal distribution in both parotid and submandibular glands. PA of major salivary glands can assume a grotesque proportion when timely surgical intervention is not sought. Complete surgical excision in benign lesions can guarantee a cure and restore self-esteem.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"99 1","pages":"92 - 96"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85807139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Ajah, B. Ozumba, R. Onoh, P. Ezeonu, C. Iyoke, I. Ezeome
{"title":"Seminal fluid features of male partners of infertility patients in southeast Nigeria","authors":"L. Ajah, B. Ozumba, R. Onoh, P. Ezeonu, C. Iyoke, I. Ezeome","doi":"10.4103/2384-5589.198320","DOIUrl":"https://doi.org/10.4103/2384-5589.198320","url":null,"abstract":"Background: Semen analysis has remained an objective, inexpensive and readily available means of assessing male factor infertility. There is a paucity of studies on male factor infertility in Nigeria using the current World Health Organization 2010 human values for semen characteristics. Aim: This study was aimed at determining the socio-demographic and semen characteristics of the male partners of infertile couples in Abakaliki. Materials and Methods: The case files of infertility cases managed at Federal Teaching Hospital from January 2011 to December 2015 were retrieved. Results: Out of 730 semen analysis results analysed, 297 (40.7%) have abnormal parameters ranging from abnormal motility (36.7%), to the combination of low sperm count, abnormal motility and morphology (0.68%). While older age and urban dwelling had significant effect on abnormal sperm motility, rural dwelling and low/or no educational status had a significant effect on low seminal fluid volume and sperm count (P-value ≤ 0.05). Conclusion: There is still a high rate of male factor infertility in this environment.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"147 1","pages":"86 - 91"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83118904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simultaneous bilateral femoral neck fracture following tetanus in a healthy adult","authors":"T. Dabkana, F. Nyaku, B. Bunu, Abubakar Timta","doi":"10.4103/2384-5589.198315","DOIUrl":"https://doi.org/10.4103/2384-5589.198315","url":null,"abstract":"A 45-year-old trader presented to us with 4 weeks history of difficulty in opening his mouth, inability to walk and tonic–clonic seizures with bilateral femoral neck fractures. Three weeks before the onset of problems, the patient had been knocked down by a tricycle and had sustained an open wound over the right medial malleolus; the wound was sutured at a general hospital and the patient discharged home. One week later, the wound started discharging a foul-smelling pus and was dressed at a primary health centre; however, by the second week, the patient started having difficulty in opening his mouth. By the third week, he was bed ridden, developed tonic–clonic seizures and felt a crunching sound associated with severe pain in both hips. He was taken to a traditional bone setter who gave him some herbs, but his symptoms got worse. He was then brought to the Accident and Emergency Department of the University of Maiduguri Teaching Hospital, Maiduguri, Borno State, Nigeria where a diagnosis of tetanus was made. Further evaluation revealed Gardener-type IV bilateral femoral neck fractures. He was managed for the tetanus, underwent bilateral bipolar hemiarthroplasty and was discharged home. He spent 10 weeks in the hospital.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"13 1","pages":"100 - 102"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80947391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Odusolu, E. Edet, C. Emechebe, T. Agan, A. Okpe, S. Etuk
{"title":"Prevalence of Chlamydia trachomatis immunoglobulin G antibody in infertile women in Calabar","authors":"P. Odusolu, E. Edet, C. Emechebe, T. Agan, A. Okpe, S. Etuk","doi":"10.4103/2384-5589.198319","DOIUrl":"https://doi.org/10.4103/2384-5589.198319","url":null,"abstract":"Background: Genital Chlamydia trachomatis infection is recognized as the single most common cause of tubal peritoneal damage leading to infertility. Knowledge of the prevalence of Chlamydia antibodies among infertile women will help determine the level of Chlamydial infection and hence its contribution to infertility. Objectives: To determine the prevalence of C. trachomatis immunoglobulin G (IgG) antibody in infertile patients and the sociodemographic characteristics and risk factors associated with infection in Calabar. Materials and Methods: This was a prospective comparative study conducted among 145 women presenting for infertility in UCTH Calabar. Another 145 women with normal pregnancies attending the antenatal clinic were used as controls. The data was analyzed using the Statistical Package for the Social Sciences (SPSS) version 18.0 (SPSS Inc, Chicago, IL, USA). A P-value of less than 0.05 was considered significant. Results: The prevalence of C. trachomatis IgG antibody was 38.6% in the infertile group and 22.8% in the pregnant controls. This difference was statistically significant (P < 0.05). Infertile women aged 30–34 years had the highest positivity rate (36.0%) for C. trachomatis antibody. Thirty-eight (42.7%) of the infertile subjects who tested positive had a history of pelvic inflammatory disease (PID) while 47 (23.4%) who tested negative had a history of PID. The difference was statistically significant (P = 0.001). Chlamydia infection was not found to be associated with any particular type of infertility (P > 0.05). Conclusion: The prevalence of C. trachomatis was higher in infertile women when compared to pregnant controls. This finding lends credence to the call for enzyme immunosorbent assay for Chlamydial IgG antibodies to be incorporated into infertility investigation in this environment.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"1 1","pages":"74 - 79"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89877253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An 80-year-old man with acute panmyelosis with myelofibrosis: A rare subtype of acute myeloid leukemia","authors":"P. Mandal, P. Prasad","doi":"10.4103/2384-5589.197968","DOIUrl":"https://doi.org/10.4103/2384-5589.197968","url":null,"abstract":"Acute panmyelosis with myelofibrosis (APMF) is a rare, fatal hematological neoplasm that is characterized by acute onset of cytopenias and fibrosis in the bone marrow in the absence of splenomegaly or fibrosis-related morphological changes in the red blood cells. We report the case of an 80-year-old male who presented with progressive pallor and weakness of 1-month duration. Peripheral smear revealed severe anemia, leukopenia with occasional circulating blasts and a normal platelet count. The marrow was heavily fibrotic, and no aspirate material could be obtained; the biopsy showed extensive infiltration with small to medium size megakaryocytes, dysplastic changes in the erythroid compartment, and focal clusters of blasts. A diagnosis of APMF was made and the patient was started on low dose lenalidomide and supportive transfusions. However, the patient died due to intracranial bleeding. Cases of APMF have a dismal outcome and should be managed aggressively.","PeriodicalId":93249,"journal":{"name":"African journal of medical and health sciences","volume":"13 1","pages":"103 - 106"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89157070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}