Archives of medical case reports最新文献

Colchicine Intoxication Subsequent to an Autolytic Attempt with Positive Evolution 秋水仙碱中毒后的自溶尝试与阳性进化

Archives of medical case reports Pub Date : 2023-10-04 DOI: 10.33696/casereports.5.028

Beatriz Nieto Martino, Walter Andrés Ramírez Lajones, Ángela Alonso Ovies

{"title":"Colchicine Intoxication Subsequent to an Autolytic Attempt with Positive Evolution","authors":"Beatriz Nieto Martino, Walter Andrés Ramírez Lajones, Ángela Alonso Ovies","doi":"10.33696/casereports.5.028","DOIUrl":"https://doi.org/10.33696/casereports.5.028","url":null,"abstract":"Background and objectives: Colchicine is a drug that has been used to treat gout for several centuries, it is also indicated in certain autoimmune diseases and has been tested as a chemotherapeutic. Only a few cases of intoxication by this drug have been described, but it is known that it has a narrow therapeutic margin (0.5 to 0.8 mg/kg), almost always resulting in fatal results above these limits. Regarding therapeutic management, the initiation of supportive measures is essential. Initial strategies are gastric lavage, administration of activated charcoal and fluid resuscitation aimed at preventing renal failure. Case report: A 63-year-old man with a history of spondylodiscitis and gouty arthropathy, receiving colchicine treatment. He reported abdominal symptoms with nausea, vomiting, watery stools, and diffuse pain after taking 36 tablets of 1 mg of colchicine due to exacerbation of arthralgias (the patient later recognized the autolytic ideation). He was hospitalized in the ICU due to hemodynamic instability, severe pancytopenia, respiratory failure requiring mechanical ventilation and non-oliguric acute renal failure. The patient improved and was discharged from the ICU after 14 days. Conclusions: Colchicine poisoning is rare and has high mortality despite the favorable evolution of our patient. There is no specific treatment at the moment and management should emphasize early admission to the ICU, close monitoring and organ support measures.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135592057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resolution of Osborn Waves after the Complete Resolution of Spontaneous Pneumothorax in a Normothermic Patient 常温患者自发性气胸完全消退后奥斯本波的消退

Archives of medical case reports Pub Date : 2023-10-04 DOI: 10.33696/casereports.5.027

Arafat Ali Farooqui, Syed Mohammad Mazhar Uddin, Sanjay Kumar Maheshwari, Omair Ali Khan, Azka Naeem, Samra Hameed, Shelly Brejt, Susan Lin

引用次数: 0

Primary Spinal Cord Haemorrhage during COVID-19 Illness: A Novel Addition to the Endless Spectrum of Neurological Manifestations? 新冠肺炎疾病期间原发性脊髓出血：神经系统无休止表现的新补充？

Archives of medical case reports Pub Date : 2023-05-15 DOI: 10.33696/casereports.4.025

M. Desai, Sunila T. Jaggi, N. Surya

引用次数: 0

Case Report of Pulmonary Embolism with Right Ventricular Strain in a Young Female 年轻女性肺栓塞伴右心室劳损1例报告

Archives of medical case reports Pub Date : 2023-05-15 DOI: 10.33696/casereports.4.026

Yvonne Walker, James P. Chiou, Miguel Diaz-Miret

{"title":"Case Report of Pulmonary Embolism with Right Ventricular Strain in a Young Female","authors":"Yvonne Walker, James P. Chiou, Miguel Diaz-Miret","doi":"10.33696/casereports.4.026","DOIUrl":"https://doi.org/10.33696/casereports.4.026","url":null,"abstract":"Acute pulmonary embolism (PE) is when one or more thrombus travel to the lungs and obstruct the pulmonary artery or one of the branches of the pulmonary tree, producing signs and symptoms immediately after the obstruction. Saddle pulmonary embolism (SPE) is a rare type of acute PE that can lead to hemodynamic instability and death. The incidence of pulmonary embolism increases with age. In women, the risk of PE increases with pregnancy, hormonal contraceptives, and hormone replacement therapy. In this case, the patient was in her forties and presented with a sudden episode of continuous dyspnea that worsened over four hours. The dyspnea was associated with palpitations and diaphoresis. The clinical scoring tools had a low pre-test probability for PE. The patient had no risk factors for PE other than being obese. Significant laboratory workup showed troponin of 0.10, D-dimer of 8.10, and a B-type natriuretic peptide (BNP) of 1,160. Her computed tomography angiography (CTA) showed extensive pulmonary emboli in the bilateral main and segmental pulmonary arteries, with findings consistent with right heart strain. The patient was managed with an unfractionated heparin loading dose in the ED based on her weight, followed by a heparin drip. Then, the patient was transferred to a tertiary medical center for further interventions. Prompt recognition and treatment of a submassive PE are fundamental to improving patient mortality and morbidity.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42327697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Small Cell Carcinoma of the Cervix: A Case Report and Literature Review 宫颈小细胞癌1例报告及文献复习

Archives of medical case reports Pub Date : 2023-05-11 DOI: 10.33696/casereports.4.023

X. Chen, Keita Mamady, Zi-guang Li, Zhao-hui Fang, Traoré Bangaly, Hong Liu

引用次数: 0

Two Cases of Burkitt Lymphoma Presenting as Solid Ovarian Masses 以卵巢实性肿块表现的伯基特淋巴瘤2例

Archives of medical case reports Pub Date : 2023-05-11 DOI: 10.33696/casereports.4.024

Blessing N. Ngam, James A. Brown, L. Elit, R. Bardin, Mark J. Snell

{"title":"Two Cases of Burkitt Lymphoma Presenting as Solid Ovarian Masses","authors":"Blessing N. Ngam, James A. Brown, L. Elit, R. Bardin, Mark J. Snell","doi":"10.33696/casereports.4.024","DOIUrl":"https://doi.org/10.33696/casereports.4.024","url":null,"abstract":"Background: Endemic Burkitt lymphoma has been associated with the Epstein Barr Virus (EBV), particularly in malaria-endemic regions. Primary ovarian Burkitt is an infrequent entity of this disease, and its diagnosis still poses a challenge.\u0000\u0000Summary: We present two cases. The first case is that of a 23-year-old female G1P1 who presented with a two-week history of abdominal pain and progressive distension. Her examination was remarkable for two pelvic masses and signs of ascites. An ultrasound scan showed bilateral solid adnexal masses, ascites, and mild splenomegaly. Tumor markers for ovarian and germ cell tumors were within the normal ranges. Cytology on ascitic fluid was negative for malignancy. Lactate dehydrogenase (LDH) level and further imaging were not done due to financial constraints. With the working diagnosis of an ovarian epithelial malignancy versus drop metastases, she underwent exploratory laparotomy, total abdominal hysterectomy, bilateral salpingo-oophorectomy, appendectomy, omentectomy, and debulking of peritoneal implants. Histopathology two weeks after surgery showed Burkitt lymphoma. The second case is that of a 12-year old female whose management averted surgery, following the recommendations made from our first case.\u0000\u0000Conclusion: Lymphomas are amongst the most common tumors in the pediatric age group. Clinicians should maintain a high index of suspicion in the face of fast-growing tumors. Burkitt lymphomas respond well to chemotherapy, and surgery is seldom necessary except for life-threatening presentations. Management of oncologic cases that are not straightforward should follow a multidisciplinary approach.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46314088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report on Ogilvie Syndrome in a Non-Surgical Candidate Ogilvie综合征一例非手术候选病例报告

Archives of medical case reports Pub Date : 2023-03-08 DOI: 10.33696/casereports.4.021

Yvonne Walker, James P. Chiou, R. Dua, Miguel Diaz-Miret

{"title":"Case Report on Ogilvie Syndrome in a Non-Surgical Candidate","authors":"Yvonne Walker, James P. Chiou, R. Dua, Miguel Diaz-Miret","doi":"10.33696/casereports.4.021","DOIUrl":"https://doi.org/10.33696/casereports.4.021","url":null,"abstract":"Ogilvie syndrome, also known as “paralytic ileus of the colon,” is characterized by pseudo- obstruction of the colon without any component of mechanical obstruction; and presents as a massively distended abdomen. If left untreated, it carries a high risk of colonic perforation and ischemia leading to death. Ogilvie syndrome usually presents as a post-surgical complication, mainly due to the lack and/or restriction of movement coupled with a possible electrolyte imbalance. In this case, the patient was a non-surgical candidate who presented with a hip fracture after a mechanical fall. Three days post-fall, she developed nausea, abdominal discomfort, and constipation during her hospitalization, which gradually resulted in a massively distended abdomen. The patient was managed conservatively with a nasogastric tube, rectal tube decompression, Metoclopramide, and Magnesium Citrate administration. Abdominal X-rays showed massively dilated bowel loops. An abdominal CT scan showed diffuse dilation of the large bowel without a transition point, suggesting obstruction favoring colonic paralytic ileus. She was discharged to a rehabilitation facility for further physical therapy.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42726211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient Right Bundle Branch Block with S1Q3T3 Pattern in Pulmonary Embolism 肺栓塞中S1Q3T3型短暂性右束支传导阻滞

Archives of medical case reports Pub Date : 2023-03-08 DOI: 10.33696/casereports.4.019

R. Chauhan, Fadi Yacoub, Parima Saxena, Mary C. Mallappallil, Sabu John

{"title":"Transient Right Bundle Branch Block with S1Q3T3 Pattern in Pulmonary Embolism","authors":"R. Chauhan, Fadi Yacoub, Parima Saxena, Mary C. Mallappallil, Sabu John","doi":"10.33696/casereports.4.019","DOIUrl":"https://doi.org/10.33696/casereports.4.019","url":null,"abstract":"A 69-year-old woman with hypertension, hyperlipidemia, sleep apnea, gastroesophageal reflux disease, and recent knee replacement was brought to the emergency room (ER) for syncope. She had her physiotherapy session earlier in the day and became symptomatic with dizziness, shortness of breath and had loss of consciousness. In the ER, systolic blood pressure (SBP) was noted to be 90 mmHg and an oxygen saturation (O2 sat) of 80% on room air. Patient received fluid bolus with improvement of SBP to 110 mmHg. O2 sat improved to 99% with 10 L of oxygen. A bedside echocardiogram showed right ventricular (RV) distension. A Computerized Tomographic Angiogram (CTA) of the chest showed bilateral main stem pulmonary emboli (PE) with signs of RV strain. Initially EKG showed sinus tachycardia, right bundle branch block, and a S1Q3T3 pattern which resolved rapidly the next day. Patient was admitted, remained hemodynamically stable, and was treated with full dose of Enoxaparin subcutaneously. A follow up EKG was performed the next day, which showed complete resolution of initial findings. Follow up echocardiogram also showed rapid resolution of RV strain and complete restoration of RV size and function. Patient was eventually discharged home on full dose apixaban.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46959375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endovascular Management of Vascular Closure Device (VCD) Thrombotic Complications 血管闭合器（VCD）血栓并发症的血管内管理

Archives of medical case reports Pub Date : 2023-03-08 DOI: 10.33696/casereports.4.022

Bola Habeb, G. Yousef

引用次数: 0

Bannayan Zonana Syndrome: An Unusual Cause of Intussusception and Protein Losing Enteropathy in a Child Bannayan Zonana综合征：儿童肠套叠和蛋白质丢失肠病的罕见原因

Archives of medical case reports Pub Date : 2023-03-08 DOI: 10.33696/casereports.4.020

Maaloul Ines, B. Mahdi, Cheikhrouhou Taycir, Z. Mohamed, Aloulou Hajer, M. Riadh, Benazzou Salma, Kamoun Thouraya

引用次数: 0