年轻女性肺栓塞伴右心室劳损1例报告

Yvonne Walker, James P. Chiou, Miguel Diaz-Miret
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摘要

急性肺栓塞(PE)是指一个或多个血栓进入肺部,阻塞肺动脉或肺动脉树的一个分支,在阻塞后立即产生体征和症状。鞍状肺栓塞(SPE)是一种罕见的急性PE,可导致血液动力学不稳定和死亡。肺栓塞的发生率随着年龄的增长而增加。在女性中,PE的风险随着怀孕、激素避孕药和激素替代治疗而增加。在这种情况下,患者四十多岁,突然出现持续呼吸困难,并在四个小时内恶化。呼吸困难与心悸和发汗有关。临床评分工具对PE的预测试概率较低。患者除了肥胖之外,没有PE的危险因素。重要的实验室检查显示肌钙蛋白为0.10,D-二聚体为8.10,B型钠尿肽(BNP)为1160。她的计算机断层扫描血管造影术(CTA)显示双侧主肺动脉和节段肺动脉有广泛的肺栓塞,其结果与右心应变一致。根据患者的体重,在急诊室使用普通肝素负荷剂量,然后滴注肝素。然后,患者被转移到三级医疗中心进行进一步干预。及时识别和治疗亚重度PE是提高患者死亡率和发病率的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case Report of Pulmonary Embolism with Right Ventricular Strain in a Young Female
Acute pulmonary embolism (PE) is when one or more thrombus travel to the lungs and obstruct the pulmonary artery or one of the branches of the pulmonary tree, producing signs and symptoms immediately after the obstruction. Saddle pulmonary embolism (SPE) is a rare type of acute PE that can lead to hemodynamic instability and death. The incidence of pulmonary embolism increases with age. In women, the risk of PE increases with pregnancy, hormonal contraceptives, and hormone replacement therapy. In this case, the patient was in her forties and presented with a sudden episode of continuous dyspnea that worsened over four hours. The dyspnea was associated with palpitations and diaphoresis. The clinical scoring tools had a low pre-test probability for PE. The patient had no risk factors for PE other than being obese. Significant laboratory workup showed troponin of 0.10, D-dimer of 8.10, and a B-type natriuretic peptide (BNP) of 1,160. Her computed tomography angiography (CTA) showed extensive pulmonary emboli in the bilateral main and segmental pulmonary arteries, with findings consistent with right heart strain. The patient was managed with an unfractionated heparin loading dose in the ED based on her weight, followed by a heparin drip. Then, the patient was transferred to a tertiary medical center for further interventions. Prompt recognition and treatment of a submassive PE are fundamental to improving patient mortality and morbidity.
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