Archives of medical case reports最新文献_第2页

Imatinib Induced Hypopigmentation and Neutropenia in a Patient with Gastric Gastrointestinal Stromal Tumor 伊马替尼诱导的胃-胃肠道间质瘤患者色素沉着减少和中性粒细胞减少

Archives of medical case reports Pub Date : 2022-11-07 DOI: 10.33696/casereports.4.015

K. Wang, Jeffrey Chi, M. Saif

引用次数: 0

A Challenging Case of Central Nervous System Involvement (CNSi) with Chronic Lymphocytic Leukemia (CLL): A Case Report 一例中枢神经系统受累伴慢性淋巴细胞白血病的挑战性病例报告

Archives of medical case reports Pub Date : 2022-11-07 DOI: 10.33696/casereports.4.018

引用次数: 0

Multiple Myeloma with Bi-clonal Gammopathy Presenting with Aggressive Disease: A Case Report 多发性骨髓瘤伴双克隆性骨髓瘤病伴侵袭性疾病1例报告

Archives of medical case reports Pub Date : 2022-11-07 DOI: 10.33696/casereports.4.016

A. M. Haidary, S. Noor, S. Noor, N. Nasir, Maryam Ahmad, Ramin Saadaat, Ahmad, Shekib Zahier, Haider Ali Malakzai, Abdul Sami Ibrahimkhil

引用次数: 0

Right Atrial Metastasis from Melanoma Treated with Immunotherapy 免疫疗法治疗黑色素瘤右心房转移

Archives of medical case reports Pub Date : 2022-11-07 DOI: 10.33696/casereports.4.017

引用次数: 0

Primary Temporal Bone Meningioma Presenting as Chronic Mastoiditis and Sigmoid Sinus Thrombosis: Report of a Case with Literature Analysis 原发性颞骨脑膜瘤表现为慢性乳突炎及乙状窦血栓形成1例并文献分析

Archives of medical case reports Pub Date : 2021-12-21 DOI: 10.33696/casereports.3.011

M. Torrez, E. Fischer, Shweta Agarwal

{"title":"Primary Temporal Bone Meningioma Presenting as Chronic Mastoiditis and Sigmoid Sinus Thrombosis: Report of a Case with Literature Analysis","authors":"M. Torrez, E. Fischer, Shweta Agarwal","doi":"10.33696/casereports.3.011","DOIUrl":"https://doi.org/10.33696/casereports.3.011","url":null,"abstract":"Primary extra cranial meningioma of the ear and temporal bone are exceedingly rare, making up less than 1% of all meningiomas. Histologically, they are indistinguishable from their intracranial counterpart. The histopathologic diagnosis is often challenging, and the differential diagnosis for neoplasms in this unusual location is quite extensive. We report a 64-year-old male patient with history of seizures who presented with coalescing mastoiditis and sigmoid sinus thrombosis. CT and MRI findings were suggestive of a chronic inflammatory process. Operative findings included a flesh-colored mass extending from the mastoid antrum posteriorly towards the Sigmoid sinus. Intraoperative consultation was requested, yielding a diagnosis favoring squamous cell carcinoma, and the decision was made to end the procedure. Additional tissue was submitted for permanent evaluation, and biopsy demonstrated a grade 1 meningioma, supported by morphologic features and immunophenotype. The clinical and histologic findings of the patient are discussed, and we emphasize the challenging nature of this rare entity, particularly with regards to intraoperative analysis. In addition, English literature is reviewed.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47718893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortical Visual Impairment (CVI): An Atypical Manifestation of Osmotic Demyelination Syndrome in a Child 皮质性视力障碍(CVI):儿童渗透性脱髓鞘综合征的非典型表现

Archives of medical case reports Pub Date : 2021-12-21 DOI: 10.33696/casereports.3.014

Najm Khan, R. Lakshmanan, Snehal Shah, L. Nagarajan

引用次数: 0

Pseudothrombocytosis Due to Red Blood Cell Fragmentation in Haemoglobin-H Disease 血红蛋白- h病中红细胞分裂引起的假性血小板增多

Archives of medical case reports Pub Date : 2021-12-21 DOI: 10.33696/casereports.3.012

A. M. Haidary, R. Azma, S. Noor, Maryam Ahmad

引用次数: 0

How to Prevent Rehospitalization in Patients with COVID-19 如何预防新冠肺炎患者再次住院

Archives of medical case reports Pub Date : 2021-12-21 DOI: 10.33696/casereports.3.013

Li Shi, Jie Chen, Jiqing He

{"title":"How to Prevent Rehospitalization in Patients with COVID-19","authors":"Li Shi, Jie Chen, Jiqing He","doi":"10.33696/casereports.3.013","DOIUrl":"https://doi.org/10.33696/casereports.3.013","url":null,"abstract":"Aim: False-negativity of reverse-transcriptase–polymerase-chain-reaction (RT-PCR) for patients with 2019 Novel Coronavirus (COVID-19) via throat swab was discussed. Method: A total of 260 patients were diagnosed with COVID-19 RT-PCR for samples obtained via throat swab. Result: Positive rates of chest Computed tomography (CT) imaging were 96.99% (252/260). Positive rates of RT-PCR were 87.70% for the first time, 92.30% for two times, and 100% for three times. Multiple RT-PCR assay tests resulted in a high positive rate of RTPCR. Combined chest CT scans and RT-PCR lead to a positive rate of 100% even for the first testing, which is conducive to COVID-19 diagnosis. Two patients with COVID-19 were discharged from hospital with false-negative results of RT-PCR using the oropharyngeal swab. There was a significant progression on CT images and an increase in infective markers during their second admission to hospital, which indicated the progressing inflammation. Patients with complete recovery were selected. Symptoms were relieved; dissipation almost completely disappeared on CT image; and infective markers significantly decreased to normal levels, which indicated that the inflammation was not progressing. percent of lymphocyte percent (LYM) increased to normal level. Conclusion: Serial follow-up chest CT scans are quite important for confirming the patients with COVID-19 who resulted negative for RT-PCR of 2019-nCoV nucleic acid. A combination of the RT-PCR test for 2019-nCoV nucleic acid and other detective methods, such as CT imaging are conducive to diagnosis. The roadmap of how to avoid being rehospitalized for patients with COVID-19 was provided. Patients were not allowed to be discharged from hospital even with negative result of RT-PCR of 2019-nCoV nucleic acid.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46421422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Avulsion of the Common Extensor Tendon and Radial Collateral Ligament Tear 总伸肌腱撕裂与桡侧副韧带撕裂

Archives of medical case reports Pub Date : 2021-12-21 DOI: 10.33696/casereports.3.010

Lance M Mabry, D. Peterson, Alicia J. Emerson

引用次数: 0

Safety and Efficacy of s-MOX Regimen in Patients with Colorectal Cancer Who Developed Cardiotoxicity Following Fluoropyrimidine Administration: A Case Series s-MOX方案治疗氟嘧啶给药后发生心脏毒性的癌症大肠癌患者的安全性和有效性：病例系列

Archives of medical case reports Pub Date : 2020-07-28 DOI: 10.33696/casereports.2.008

M. Ehrlich, Kristin Kaley, M. Smith, M. Saif

{"title":"Safety and Efficacy of s-MOX Regimen in Patients with Colorectal Cancer Who Developed Cardiotoxicity Following Fluoropyrimidine Administration: A Case Series","authors":"M. Ehrlich, Kristin Kaley, M. Smith, M. Saif","doi":"10.33696/casereports.2.008","DOIUrl":"https://doi.org/10.33696/casereports.2.008","url":null,"abstract":"Background: Fluoropyrimidines compose the backbone of regimens to treat many common solid tumors, including gastrointestinal (GI), breast and head/neck. As we continue to use these agents routinely, recognition of rare but real toxicities, such as cardiotoxicity, has also improved. The treatment options for patients who have encountered fluoropyrimidine-induced cardiotoxicity are limited as many anti-angiogenic drugs also pose a cardiac risk. Patients and Methods: We present a case series of three patients who developed cardiotoxicity in the form of anginal-like symptoms, EKG changes and elevated cardiac enzymes on infusional 5-FU or capecitabine and were subsequently treated with the s-MOX (simplified-mitomycin-oxaliplatin) regimen for their metastatic colorectal cancer (mCRC). All three patients were tested for polymorphic abnormality of DYPD and TYMS. Results: All three patients were treated with s-MOX consisting of mitomycin-C 7 mg/m2 on day 1 and oxaliplatin 85 mg/m2 on days 1 and 15 (1 cycle = 28 days) after they encountered cardiotoxicity to 5-FU and/or capecitabine. None of these patients developed any cardiotoxicity on s-MOX. Overall, the MOX regimen was well tolerated. The most common toxicities included ≤ 2 grade peripheral neuropathy, nausea, vomiting, thrombocytopenia, and anemia. Grade ≥ 3 toxicities included neutropenia (10%), thrombocytopenia (33%), vomiting (8%), and peripheral neuropathy (30%). DYPD gene was normal in all patients and TYMS was abnormal (2R/2R) in one patient. Conclusion: This is the first case series that reports the safety and feasibility of s-MOX in patients with mCRC who developed cardiac toxicity to 5-FU or capecitabine. The s-MOX regimen may provide an alternative treatment option for patients who either develop fluoropyrimidine-related cardiotoxicity or who have abnormalities in the DYPD gene.","PeriodicalId":93075,"journal":{"name":"Archives of medical case reports","volume":"2 1","pages":"23 - 29"},"PeriodicalIF":0.0,"publicationDate":"2020-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45503185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3