American journal of biomedical science & research最新文献

{"title":"An Atypical Presentation of a Patient with Renal Abscess","authors":"L. Ranasinghe","doi":"10.34297/ajbsr.2021.13.001939","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001939","url":null,"abstract":"Renal and perirenal abscesses are two uncommon diagnoses that carry the potential for significant mortality, but those entities often present with vague and nonspecific symptoms as demonstrated with our patient. In earlier decades, case fatality rates for these conditions were as high as 39-50% [1]. More recent studies have shown mortality rates ranging from 0-7% [2]. Incidence is presently estimated at 1-10 per 10,000 admissions, and increases with predisposing conditions such as diabetes mellitus, obstructing stones, and other urinary tract abnormalities [3]. The most common risk factor for both conditions has consistently been shown to be diabetes mellitus [2,4].","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47836000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soil Moisture and Dendrometer Sampling of Kent Trees Irrigated with Micro-Sprinklers","authors":"F. Hahn","doi":"10.34297/ajbsr.2021.13.001940","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001940","url":null,"abstract":"Mexico is the leading mango exporter worldwide and requires to optimize yield; quality and water use. Water shortage due to climatic changes can affect yield production and quality by increasing fruit drop and size. In the period 2018-2020 decrease in raining events reduced mango yields. Sustained deficit irrigation (SDI) techniques have been applied worldwide and four holes were dig to wet each tree by means of a micro-sprinkler irrigation system. Soil moisture content around the trees were acquired and compared against those irrigated all around the tree trunk. Also dendrometer measurements at the branches help to understand water dynamics within the tree; and high yields were obtained when branches had good water uptake. It was found that roots are closer to the surface and that dry soil areas beneath branches did not provided enough water to produce mangoes over 350 grams.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45525294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Warm, Humidified High-Flow Filtered Air Therapy Be Protective Against Severe Infection from Sars-Cov-2 and Other Respiratory Pathogens?","authors":"S. Amatya","doi":"10.34297/ajbsr.2021.13.001937","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001937","url":null,"abstract":"Can Humidified High-Flow Filtered Air Therapy Be Protective Against Severe Infection from Sars-Cov-2 and Other Respiratory Pathogens?.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48456351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Coral as a Biomaterial Revisited","authors":"L. Yahia","doi":"10.34297/ajbsr.2021.13.001936","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001936","url":null,"abstract":"This paper first describes the state of the art of natural coral. The biocompatibility of different coral species has been reviewed and it has been consistently observed that apart from an initial transient inflammation, the coral shows no signs of intolerance in the short, medium, and long term. Immune rejection of coral implants was not found in any tissue examined. Other studies have shown that coral does not cause uncontrolled calcification of soft tissue and those implants placed under the periosteum are constantly resorbed and replaced by autogenous bone. The available studies show that the coral is not cytotoxic and that it allows cell growth. Thirdly, porosity and gradient of porosity in ceramics is explained based on far from equilibrium thermodynamics. It is known that the bone cross-section from cancellous to cortical bone is non-uniform in porosity and in pore size. Thus, it is hypothesized that a damaged bone containing both cancellous and cortical bone can be better replaced by a graded/gradient porous implant based on the idea of a biomimetic approach. The purpose of this article is to review and summarize all the pertinent work that has been published on natural coral as a bone graft during the last twenty years including in vitro , animal, and clinical human studies. In addition, as an illustration, we report the clinical experience of one of us using coral. It is a case study of complex femoral fracture (Table 1) where the essential role of vascularization and stabilization of the fracture site are underlined. The results are supported with more than 300 other femoral fractures treat- ed using the same modus operandi. Finally, this paper overviews the ecological and ethical concerns around the use of corals as well as discussing briefly about recent impacts of nano-pollutants. Abstract This is the story of a patient that has been hospitalized following a car accident for a complex fracture of the lower third of the femur. However, the bones non-union is confirmed. It was then necessary to perform another surgery, removing the initial material in addition to carrying out an anatomical reduction. A screwed plate- blade Poitout, et al. [95,96] and a biomaterial graft Cirotteau, [97,98] are performed to stimulate new osteosynthesis. Consolidation took 4 months; the femoral shaft is anatomically reconstructed in 1 year and there were no sequelae. The follow-up was made on a period over 2 years. This case study highlights, among other things, the essential role of vascularization. And the results are supported by more than 300 other femoral fractures treated according to the same surgical procedure. ne an emergency surgery when came the hospital. The lower third of her femur was fractured. It was a complex fracture including bone non-union. The femur was osteo-synthesized using a long plate. The patient refuses a re-operation proposed by the second","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49177781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Some Books Leave Out: Recent Cases of Negative Bias","authors":"W. Schumm","doi":"10.34297/ajbsr.2021.13.001935","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001935","url":null,"abstract":"Citation bias and confirmation bias, as well as various forms of scientific misconduct, are well known concerns within the scientific community. Such types of bias usually oversell scientific or theoretical arguments. Here another type of bias, negative bias, is when authors undersell their argu ments by overlooking scientific evidence that would support or would have supported their arguments. Scholars need to be aware of the potential for both types of bias, positive and negative, when evaluating the research literature and preparing literature reviews.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44481664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Fifty Trace Element Contents in Macro and Micro Follicular Colloid Nodular Goiter","authors":"V. Zaichick","doi":"10.34297/ajbsr.2021.13.001931","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001931","url":null,"abstract":"Background: Colloid nodular goiter (CNG) is the most common disease of the thyroid, even in non-endemic regions, but an etiology of CNG is unclear. It is known that not only iodine (I) but other trace elements (TE) are involved in goitrogenesis. The present study was performed to clarify the preferential accumulation of some TE either in the colloid or in cells of the thyroid gland. Methods: Fifty TE (Ag, Al, As, Au, B, Be, Bi, Cd, Ce, Co, Cr, Cs, Dy, Er, Eu, Fe, Ga, Gd, Hg, Ho, Ir, La, Li, Lu, Mn, Mo, Nb, Nd, Ni, Pb, Pd, Pr, Pt, Rb, Sb, Sc, Se, Sm, Sn, Tb, Te, Th, Ti, Tl, Tm, U, Y, Yb, Zn, and Zr) in the thyroid tissues with diagnosed CNG were prospectively evaluated in 16 patients with macro-follicular CNG and 13 patients with micro-follicular CNG. Control group included thyroid tissue samples from 105 healthy individuals. Mea- surements were performed using a combination of non-destructive instrumental neutron activation analysis with inductively coupled plasma mass spectrometry. Results: It was found that with a goitrous transformation the Ag, Al, B, Bi, Co, Er, Fe, Hg, Mo, Nd, Ni, Pb, Pr, Rb, Tl, U, Y, and Zn level in thyroid tissue can be significantly changed, and these changes depend on CNG histology. An association between B and Pb content and cell volume of CNG was observed. Conclusion: thyroid, which depend on the histology of goiter.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44725409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Most Logical Cancer Therapy Concept in The World?","authors":"M. Doepp","doi":"10.34297/ajbsr.2021.13.001934","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001934","url":null,"abstract":"If one looks at the statistics on cancer incidence worldwide and at the cure rates at least over 5 years you will see that we are further away than ever from beating cancer (as President Nixon announced at the time). There are cancers where cure rates are close to zero, and there are others whose incidence is exploding. The predominant therapy still consists of the old trias: scalpel, chemotherapy and radiation. In the field of chemotherapy, new ways and means are constantly being brought onto the market, such as immunotherapy. It is very expensive and has only slightly increased cure rates. One problem is regularly that the untargeted chemotherapy kills the sensitive cells but does not reach the resistant cells. These can then multiply at will.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47170708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recombinant Protein of Immunogenic Metabolic Enzyme Epitopes of Trichomonas vaginalis are Common to Humans and Microorganisms","authors":"J. Alderete","doi":"10.34297/ajbsr.2021.13.001930","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001930","url":null,"abstract":"Protein Immunogenic Metabolic Enzyme Epitopes vaginalis are Common to Abstract The number one, non-viral sexually transmitted infection (STI) worldwide is caused by the ancient protist . Recently, I reported on an ~40-kDa String-Of-Epitopes chimeric protein (AEG::SOE2) consisting of immunogenic epitopes unique to the vaginalis fructose-1,6bisphosphate aldolase (A), α -enolase (E), and glyceraldehyde-3-phosphate dehydrogenase (G). This report is on another construct of a 49.41-kDa AEG::SOE3 chimeric protein comprised of 8, 9 and 12 non-unique, immunogenic epitopes of A, E and G, respectively. These non-unique epitopes were detected by sera of women and men patients but not control, seronegative sera of women and men. The epitopes were found to have ≥50% to 100% sequence amino acid sequence identity with the human homolog and homologs of Candida albicans, Escherichia coli, Saccharomyces cerevisiae, Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes as well as the homologs of the STI agents Chlamydia trachoma- tis, Neisseria gonorrhoeae and Treponema pallidum . The AEG::SOE3 protein was not detected by mouse anti AEG::SOE2 serum and by monoclonal antibodies (MAbs) to AEG::SOE2, showing the distinctness of these two chimeric proteins. AEG::SOE3 was detected by ELISA and immunoblot with sera of mice immunized with fixed T. vaginalis organisms, with sera of women and men patients with trichomonosis, and with MAbs to AEG::SOE3. The patient sera reactive to these immunogenic metabolic enzyme epitopes of AEG::SOE3 may be indicative of immune-crossreactive antibodies to human proteins during this STI. The role of these possible immune-crossreactive antibodies produced during this STI and those conceivably gener- ated by other STIs and microbial pathogens to heretofore unappreciated disease pathogenesis is discussed.","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47771204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Chinese Medicine and COVID-19","authors":"Di Shen","doi":"10.34297/ajbsr.2021.13.001932","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001932","url":null,"abstract":"","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69883140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Microbiological Basis of Human Superorganism Freedom","authors":"Rodney R Dietert","doi":"10.34297/ajbsr.2021.13.001933","DOIUrl":"https://doi.org/10.34297/ajbsr.2021.13.001933","url":null,"abstract":"This opinion article looks at the relationship between human biological make-up, (e.g., the biology, microbiology, genes, and human genetics), and the human condition on earth looking across two centuries. For the mid-20th century, I examine the work of the great Ukrainian-American geneticist and evolutional biologist, Theodosius Dobzhansky, with an emphasis on three key aspects of his life and career 1. His landmark theorems on genetic variability and adaptability, 2. His science- driven vision of human nature, why humans are born free and what we must do to remain free, and finally, 3. Dobzhansky’s decades long personal struggle to call out non-science masquerading as science-driven policy (the Lysenko debacle). Trofim Lysenko’s disastrous agronomy program based on anti-genetics and non-science was heralded by political leaders and media alike, dom - inated food production in two Communist countries, resulted in horrific famine and mass starvation, and was allowed to continue across decades. Dobzhansky’s individual opposition to this misuse of science that created human suffering and death was juxtaposed to the virtual silence of U.S. major genetics organizations. Five rules for having and keeping freedom are presented from Dobzhansky’s 1956 human freedom treatise. Now in the 21st century, there are interesting parallels to be made. Dobzhansky’s genetics are updated to include the microbiome and the reality that we are by several measures, mainly microbial taking form as a human superorganism/holobiont. With earth being a microbial planet and humans representing a microcosm of that life, our place on earth as envisioned by Dobzhansky is even more solidified. Finally, I examine the prolonged microbiome-destroying, im -mune-altering public health mandates instituted for the SARS-CoV-2 pandemic that increasingly impinge upon human freedoms all in the name of science. It is useful to ask: What would Dobzhansky have to say about genes and human freedom today?","PeriodicalId":93072,"journal":{"name":"American journal of biomedical science & research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49041247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}