Livestock production science最新文献_第2页

Author index–volumes 92–98 (2005) 作者索引——第92卷至第98卷（2005年）

Livestock production science Pub Date : 2005-12-30 DOI: 10.1016/S0301-6226(05)00369-6

引用次数: 0

17β-estradiol reduces milk synthesis and increases stanniocalcin gene expression in the mammary gland of lactating cows 17β-雌二醇可减少泌乳奶牛乳腺中的乳合成，增加斯坦钙素基因表达

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.010

L. Delbecchi , N. Miller , C. Prud'homme , D. Petitclerc , G.F. Wagner , P. Lacasse

{"title":"17β-estradiol reduces milk synthesis and increases stanniocalcin gene expression in the mammary gland of lactating cows","authors":"L. Delbecchi , N. Miller , C. Prud'homme , D. Petitclerc , G.F. Wagner , P. Lacasse","doi":"10.1016/j.livprodsci.2005.10.010","DOIUrl":"10.1016/j.livprodsci.2005.10.010","url":null,"abstract":"<div><p>Increasing amounts of estrogens in the blood of pregnant lactating cows may be one factor inducing the progressive involution of the mammary gland after the peak of lactation. The present study was undertaken to assess the effects of 17β-estradiol on milk production and to analyze its mechanism of action at the molecular level. Non-pregnant, mid-late lactation cows received daily sc. injections of either 17β-estradiol (treated, <em>n</em>  =4). Treated cows showed a reduction in dry matter intake and presented signs of mammary gland involution, as indicated by their lowered milk production and modified milk composition. Real-time RT-PCR, performed on RNA extracted from mammary biopsies, showed that 17β-estradiol reduced the mRNA levels of β-casein, did not affect those of Bax and Bcl-2 but increased those of stanniocalcin, a hormone that regulates epithelial calcium and phosphate transport. Moreover, concentration of stanniocalcin was increased in the milk and serum of treated cows. Thus, our results indicate that the effect of 17β-estradiol on milk production is not mediated by Bax or Bcl-2 while they suggest a possible role for stanniocalcin in mammary involution.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 57-66"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55270135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27

Milk accumulation decreases expression of genes involved in cell–extracellular matrix communication and is associated with induction of apoptosis in the bovine mammary gland 乳汁积累降低了参与细胞外基质通讯的基因的表达，并与诱导乳腺细胞凋亡有关

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.016

K. Singh , J. Dobson , C.V.C. Phyn , S.R. Davis , V.C. Farr , A.J. Molenaar , K. Stelwagen

{"title":"Milk accumulation decreases expression of genes involved in cell–extracellular matrix communication and is associated with induction of apoptosis in the bovine mammary gland","authors":"K. Singh , J. Dobson , C.V.C. Phyn , S.R. Davis , V.C. Farr , A.J. Molenaar , K. Stelwagen","doi":"10.1016/j.livprodsci.2005.10.016","DOIUrl":"10.1016/j.livprodsci.2005.10.016","url":null,"abstract":"<div><p>Forty-eight primiparous, non-pregnant, Friesian cows in mid-lactation, were used to investigate the cell–extracellular matrix (ECM) communication in mammary epithelial cell (MEC) survival during induced mammary involution and to examine cell survival and apoptotic signalling events. Cows were sacrificed and alveolar mammary tissue was obtained at 0, 6, 12, 18, 24, 36, 72 and 192 h (<em>n</em>  <!-->6 per group) after termination of milking. Tissue mRNA concentrations, measured by quantitative real-time RT–PCR, of different integrins (β1, α6 and α5), down-stream signal transduction factors FAK and 14-3-3, and cell survival members BAG-1 and Bcl-x<sub>long</sub> of the Bcl-2 family were decreased by 24 h compared to 6 h, with no further decrease to 8 days (192 h). The pro-apoptotic member of the Bcl-2 family, αBax mRNA level was increased by 8 days. Apoptosis within the epithelial cell layer surrounding the alveolar lumen, measured by in situ end-labelling (ISEL), was evident. There were a low number of ISEL nuclei, in lactating mammary tissue (6 h), which was increased by 72 h of involution. By 8 days of induced involution, there was a dramatic increase in apoptotic products within the lumen, accounting for the majority of total apoptotic cells, which was accompanied by neutrophil infiltration. In conclusion, cell–ECM communication becomes compromised in the bovine mammary gland 18–24 h after termination of milking, as indicated by a decrease in the expression of integrins and cell survival factors. The different down-regulated integrins implicate crosstalk between integrins and growth factor receptors may occur during involution of the bovine mammary gland. Pro-apoptotic factors are up-regulated by 8 days of involution.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 67-78"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55271070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 47

Retinoids and steroids in bovine mammary gland immunobiology 牛乳腺免疫生物学中的类维生素a和类固醇

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.011

E. Meyer, I. Lamote, C. Burvenich

{"title":"Retinoids and steroids in bovine mammary gland immunobiology","authors":"E. Meyer, I. Lamote, C. Burvenich","doi":"10.1016/j.livprodsci.2005.10.011","DOIUrl":"10.1016/j.livprodsci.2005.10.011","url":null,"abstract":"<div><p>Major variations in systemic retinoid and steroid levels during the periparturient period suggest that these potent signaling molecules play a role in the decreased innate immune response observed at early lactation. This period coincides with a marked increase in the incidence of coliform mastitis. Two critical parameters have been identified within the cow's first line of defense during acute coliform mastitis: efficient mammary epithelium remodeling and functional polymorphonuclear leukocytes. The overall aim of this review is to relate the actual knowledge on retinoids and steroids to bovine mammary gland immunobiology. Recent insights on the potential role of retinoic acid, estradiol and progesterone in the development and maintenance of a normal glandular epithelial architecture are provided. In parallel, their influence on myelopoiesis and PMN functionality is also discussed. Retinoic acid and steroid hormones predominantly serve as ligands that activate specific transcription factors belonging to a nuclear receptor superfamily and thereby control gene expression. Additionally, both retinoids and steroids may act via non-nuclear receptor mediated pathways. There are also indications on a subtle interplay between retinoic acid and estrogen pathways. These messengers probably affect cell proliferation and apoptosis through interaction with local growth factors e.g., the insulin-like growth factor /insulin-like growth factor binding protein-axis, and with the extracellular matrix e.g., by modulating matrix metalloproteinase activity. In conclusion, arguments are provided supporting the importance of retinoids and sex steroid hormones in the mammary gland innate immune defense.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 33-46"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55270666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Intracrine signaling in the mammary gland 乳腺中的分泌信号

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.005

Craig R. Baumrucker

{"title":"Intracrine signaling in the mammary gland","authors":"Craig R. Baumrucker","doi":"10.1016/j.livprodsci.2005.10.005","DOIUrl":"10.1016/j.livprodsci.2005.10.005","url":null,"abstract":"<div><p>The concept of paracrine/autocrine regulation of cellular mechanisms by peptide regulators acting through cell surface receptors and generating a cascade of intracellular second messengers is highly established. Recent evidence is accumulating that peptide regulatory factors can act within the cell (without plasma membrane signaling receptors) and this action has been coined “intracrine”. The locus of many intracrine actions appears to be the nucleus. Evidence also indicates that insulin-like growth factor binding protein-3 (IGFBP-3) directly interacts with nuclear receptors. We and others have indicated that lactoferrin (Lf) and IGFBP-3 are also intracrine factors and these proteins appear on the putative list of potential intracrine factors. These proteins have a signal sequence and are secreted from cells. Additionally, they have nuclear localization sequences (NLS) and have been shown to sequester in the nuclear compartment of some cells. While IGFBP-3 has been linked to retinoid receptors and signaling, the mechanism of cellular internalization and the resulting phenotypic effect has remained unclear. However, a recent study has indicated that nucleolin may be responsible for Lf binding as well as translocation to the nuclear compartment. We hypothesize that the high regulation, high synthesis and secretion rates of Lf and IGFBP-3 by mammary cells provide the opportunity to be critical regulators of mammary gland development and differentiation via nucleolin and retinoid receptors.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 47-56"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55270273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Lactation and lactational effects on metabolism and reproduction in the horse mare 哺乳和哺乳对马母代谢和繁殖的影响

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.003

Katharina Deichsel, Jörg Aurich

{"title":"Lactation and lactational effects on metabolism and reproduction in the horse mare","authors":"Katharina Deichsel, Jörg Aurich","doi":"10.1016/j.livprodsci.2005.10.003","DOIUrl":"10.1016/j.livprodsci.2005.10.003","url":null,"abstract":"<div><p>Prolactin plays a major role for lactogenesis and for the initiation but not the maintenance of lactation in the horse. While experimentally supplemented or naturally occurring dopamine agonists inhibit the onset of lactation in the mare via a reduction in prolactin release, treatment with dopamine antagonists stimulates lactation. In lactating mares, follicular growth and ovulation are resumed early postpartum and are not prevented by suckling or by the presence of a foal. Lactational anoestrus does not exist as a physiological condition in the horse. Mares are able to meet the increased energy expenditure during lactation mainly by increasing feed intake while mobilisation of body reserves is limited. Plasma leptin concentrations are reduced after foaling. Plasma IGF-1 levels increase in late gestation, reach a maximum at foaling and decrease gradually thereafter. After foaling, LH release increases and reaches levels comparable to non-lactating mares. This increase, together with simultaneously high IGF-1 concentrations, may stimulate the rapid resumption of cyclic ovarian activity within less than 2 weeks after foaling.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 25-30"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55270233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Vitamin E in dairy cows 奶牛中的维生素E

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.004

A. Baldi

引用次数: 56

Folic acid and vitamin B12 requirements of dairy cows: A concept to be revised 奶牛的叶酸和维生素B12需要量:一个有待修订的概念

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.009

C.L. Girard, J.J. Matte

{"title":"Folic acid and vitamin B12 requirements of dairy cows: A concept to be revised","authors":"C.L. Girard, J.J. Matte","doi":"10.1016/j.livprodsci.2005.10.009","DOIUrl":"10.1016/j.livprodsci.2005.10.009","url":null,"abstract":"<div><p>Based on a limited number of research studies conducted on steers, it seems that the supply in folic acid could be limiting based on estimated ruminal synthesis and dietary supply. Folic acid has the single, important biochemical function in mammals to accept and release one-carbon units. This role is essential for the synthesis of purine and pyrimidine and the de novo provision of methyl groups for formation of the primary methylating agent, <em>S</em>-adenosylmethionine. Given its metabolic roles, folic acid is critical for cell division and protein metabolism, and therefore is an ideal candidate to begin with while reviewing B-vitamin requirements of dairy cow for an optimal productivity. Moreover, metabolisms of folic acid and vitamin B<sub>12</sub> are closely linked, utilization of folates by cells being dependent of vitamin B<sub>12</sub> supply. Studies reported in the present paper demonstrate that the supply in these two B-vitamins is not always sufficient to maximize health and productivity of dairy cows. Supplementation in those vitamins, especially during early lactation, improved lactational performance, metabolic efficiency and nutritional quality of milk. However, other research needs to be conducted to overcome the problems caused by the massive destruction of dietary supplements of those vitamins in rumen.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 123-133"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55270593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 53

Postpartum endocrinology and prospects for fertility improvement in the lactating riverine buffalo (Bubalus bubalis) and yak (Poephagus grunniens L.) 产乳期水牛和牦牛的产后内分泌学及提高生育力的前景

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.014

B.S. Prakash , M. Sarkar , Vijay Paul , D.P. Mishra , A. Mishra , H.H.D. Meyer

{"title":"Postpartum endocrinology and prospects for fertility improvement in the lactating riverine buffalo (Bubalus bubalis) and yak (Poephagus grunniens L.)","authors":"B.S. Prakash , M. Sarkar , Vijay Paul , D.P. Mishra , A. Mishra , H.H.D. Meyer","doi":"10.1016/j.livprodsci.2005.10.014","DOIUrl":"10.1016/j.livprodsci.2005.10.014","url":null,"abstract":"<div><p>In many Asian countries the riverine buffalo is the major milk producing animal besides contributing towards draught power and meat production. The animal however suffers from inherent reproductive problems such as poor estrus expression and long calving intervals which limits its lifetime production. The yak is a seasonal breeder and the mainstay of highlanders and tribal populations inhabiting the inhospitable terrains of the Himalayan region. The factors responsible for its seasonality include poor nutrition, harsh climate and high altitude. Very little information is available on postpartum endocrinology in riverine buffaloes and even less so in yaks in relation to milk yield and cyclicity commencement. Our recent investigations on endocrine changes associated with cyclicity commencement in buffaloes (Murrah breed) showed a positive correlation between plasma prolactin concentrations and delay in postpartum cyclicity commencement. A significant correlation of plasma GH concentration with milk yield was also obtained. Monitoring cyclicity through milk progesterone analysis in buffaloes postpartum indicated that the incidences of silent estrus was low in winter months and very high in summer months — the overall annual mean being 37%. Preovulatory LH surges post-estrus occurred at different times resulting in ovulations at 28 to 60 h after onset of spontaneous estrus in buffaloes. Progesterone profiles in some yaks indicated cyclic activity even during non-breeding season. The positive correlation between plasma prolactin and melatonin indicates valuable evidence for their role in reproduction in this animal.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 13-23"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55270909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

Present knowledge and unexpected behaviours of vitamins A and E in colostrum and milk 介绍初乳和牛奶中维生素A和E的知识和意外行为

Livestock production science Pub Date : 2005-12-01 DOI: 10.1016/j.livprodsci.2005.10.008

C. Debier, J. Pottier, Ch. Goffe, Y. Larondelle

{"title":"Present knowledge and unexpected behaviours of vitamins A and E in colostrum and milk","authors":"C. Debier, J. Pottier, Ch. Goffe, Y. Larondelle","doi":"10.1016/j.livprodsci.2005.10.008","DOIUrl":"10.1016/j.livprodsci.2005.10.008","url":null,"abstract":"<div><p>Vitamins A and E are fat-soluble nutrients that exert various important roles especially during the early stages of life. Vitamin E is required to protect the newborn against oxidative stress and vitamin A is fundamental for growth and development. Both nutrients are also essential to ensure a good functioning of the immune system of the young. For these reasons and because of their limited placental transfer, vitamins A and E must be provided to the neonates in adequate amounts, in order to avoid a deficiency and maximize their disease resistance. Colostrum contains very high concentrations of vitamins A and E as compared to mature milk. The transfer of both nutrients into the milk does not seem to occur through a passive mechanism following the transfer of lipids. Supplementing gestating and lactating mothers appears to improve vitamin E levels in the milk and in the serum of neonates. The same phenomenon is also observed for milk vitamin A levels. However, the effect on the young seems to be less obvious. Even if much remains to be done concerning the metabolism of vitamins A and E during lactation, studies using seals as models have brought light on several important aspects of the transfer of vitamins A and E from mother to offspring.</p></div>","PeriodicalId":92934,"journal":{"name":"Livestock production science","volume":"98 1","pages":"Pages 135-147"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.livprodsci.2005.10.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55270492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 63