Breathe最新文献_第2页

Benefits of participating in the Lung Science Conference for early career respiratory experts.

IF 2.3

Breathe Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0290-2024

Anja Schweikert, Antonella F M Dost, Heleen Demeyer, Sara Cuevas Ocaña

引用次数: 0

Diagnosis and management of comorbid disease in COPD.

IF 2.3

Breathe Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0099-2024

Eleanor Cronin, Breda Cushen

引用次数: 0

Diaphragm dysfunction: how to diagnose and how to treat?

IF 2.3

Breathe Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0218-2024

Filipa Jesus, Anda Hazenberg, Marieke Duiverman, Peter Wijkstra

{"title":"Diaphragm dysfunction: how to diagnose and how to treat?","authors":"Filipa Jesus, Anda Hazenberg, Marieke Duiverman, Peter Wijkstra","doi":"10.1183/20734735.0218-2024","DOIUrl":"10.1183/20734735.0218-2024","url":null,"abstract":"The diaphragm, crucial for respiratory function, is susceptible to dysfunction due to various pathologies that can affect the nervous system, neuromuscular junction or the muscle itself. Diaphragmatic dysfunction presents with symptoms ranging from exertional dyspnoea to respiratory failure, significantly impacting patients' quality of life. Diagnosis involves clinical evaluation complemented by imaging and pulmonary function tests. Chest radiography, fluoroscopy, and ultrasonography are pivotal in assessing diaphragmatic movement and excursion, offering varying sensitivities and specificities based on the type and severity of dysfunction. Ultrasonography emerges as a noninvasive bedside tool with high sensitivity and specificity, measuring diaphragm thickness, thickening fraction, and excursion, and enabling monitoring of disease progression and response to treatment over time. Treatment strategies depend on the underlying aetiology and severity, ranging from conservative management to interventions such as surgical plication or diaphragmatic pacing. Ventilatory support, particularly noninvasive ventilation, plays a pivotal role in treatment, enhancing lung function and patient outcomes across unilateral and bilateral dysfunction. Despite advances in diagnostic techniques, awareness and systematic evaluation of diaphragmatic function remain inconsistent across clinical settings. This review consolidates the current understanding of diaphragmatic dysfunction, highlighting diagnostic modalities and treatment options to facilitate early recognition and management of this entity.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 1","pages":"240218"},"PeriodicalIF":2.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A puzzling case of pulmonary infiltrates in a young man with chronic kidney disease.

IF 2.3

Breathe Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0174-2024

Luca Palazzolo, Ilaria Bassi, Aldo Guerrieri, Maurizio Zompatori, Giorgia Dalpiaz, Lara Pisani

引用次数: 0

Benign obstetric and gynaecological diseases associated with pleural effusion: a narrative review.

IF 2.3

Breathe Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0238-2024

Lucía Ferreiro, María E Toubes, Nuria Rodríguez-Núñez, Luis Valdés

引用次数: 0

An educational programme for home mechanical ventilation in motor neuron disease.

IF 2.3

Breathe Pub Date : 2025-02-25 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0094-2024

Federica Riva-Rovedda, Marco Clari, Alessio Conti, Tiziana Esposito, Giuseppe Tabbia, Alessio Mattei, Andrea Calvo, Paolo Solidoro, Valerio Dimonte

{"title":"An educational programme for home mechanical ventilation in motor neuron disease.","authors":"Federica Riva-Rovedda, Marco Clari, Alessio Conti, Tiziana Esposito, Giuseppe Tabbia, Alessio Mattei, Andrea Calvo, Paolo Solidoro, Valerio Dimonte","doi":"10.1183/20734735.0094-2024","DOIUrl":"10.1183/20734735.0094-2024","url":null,"abstract":"Respiratory failure represents the leading cause of death among people with motor neuron disease (MND). Home mechanical ventilation supports respiratory function, but its management places a significant demand on patients and informal caregivers. The need for consistent support to deal with home mechanical ventilation is recognised. Regardless, specific educational interventions are infrequently reported. Within its multidisciplinary clinical care pathway, the Regional Expert Centre for MND of a Northern Italy university hospital offers patients and their caregivers an educational programme on how to deal with noninvasive ventilation (NIV) and invasive mechanical ventilation (IMV) at home. NIV education is usually performed in an outpatient setting. Pneumologists and nurses train patients and caregivers about ventilator functions, management of respiratory interfaces, inhalation therapy, skin integrity preservation and respiratory deterioration detection, while respiratory therapists train patients and caregivers about the use of an assisted cough device. IMV education is performed at the hospital. Respiratory therapists, supported by nurses, train caregivers about ventilator functions, management of tracheostomy cannula, tracheal suction, inhalation therapy and use of assisted cough devices. Finally, a certification of the skills acquired is released. Future studies should assess the effectiveness of this programme in terms of satisfaction and clinical outcomes.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 1","pages":"240094"},"PeriodicalIF":2.3,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11851158/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reflections of a paediatric pulmonologist: strategies for optimising lung function tests in preschool children.

IF 2.3

Breathe Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0178-2024

Radu Marian Gheorghiu, Iustina Violeta Stan

{"title":"Reflections of a paediatric pulmonologist: strategies for optimising lung function tests in preschool children.","authors":"Radu Marian Gheorghiu, Iustina Violeta Stan","doi":"10.1183/20734735.0178-2024","DOIUrl":"10.1183/20734735.0178-2024","url":null,"abstract":"In recent years, our clinical practice as paediatric pulmonologists has focused on refining strategies to optimise pulmonary function tests (PFTs) for preschool children, particularly those aged as young as 2 years and 5 months. This viewpoint reflects on our experience conducting over 7000 spirometry and impulse oscillometry (IOS) tests, sharing practical insights into achieving high success rates with young children. We emphasise the importance of creating a child-friendly, minimally stimulating environment, tailored communication using familiar and engaging language, and leveraging gamification and positive reinforcement. In particular, we highlight the use of role-playing as an effective engagement strategy, allowing children to teach a stuffed toy how to perform the test. Furthermore, we differentiate the approaches required for spirometry, which demands active cooperation, and IOS, which allows for tidal breathing and is more suitable for younger or less cooperative children. Through these strategies, we have achieved consistent, technically acceptable results in preschool-aged children, aligning with the latest standardisation guidelines. Our findings demonstrate the value of adaptability, patience and creativity in paediatric PFTs, suggesting that these approaches improve not only test accuracy but also the overall experience for both children and caregivers. Future research should further investigate these techniques to enhance paediatric pulmonary testing protocols.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 1","pages":"240178"},"PeriodicalIF":2.3,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11747874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-risk pulmonary embolism in a post-operative patient.

IF 2.3

Breathe Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0101-2024

Jordan Talan, Brian Reuland, Brian Kaufman, Anthony Andriotis

引用次数: 0

From basic scientific research to the development of new drugs for pulmonary arterial hypertension: insights from activin-targeting agents.

IF 2.3

Breathe Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0116-2024

Christophe Guignabert

{"title":"From basic scientific research to the development of new drugs for pulmonary arterial hypertension: insights from activin-targeting agents.","authors":"Christophe Guignabert","doi":"10.1183/20734735.0116-2024","DOIUrl":"10.1183/20734735.0116-2024","url":null,"abstract":"Pulmonary arterial hypertension (PAH) is a severe disorder of the pulmonary vasculature leading to right ventricular failure. This pulmonary vascular remodelling leads to increased pulmonary vascular resistance and high pulmonary arterial pressures. Despite the development of new therapies, many patients continue to experience significant morbidity and mortality. This review offers a comprehensive overview of the current understanding of PAH pathophysiology, with a focus on key mechanisms that contribute to pulmonary endothelial cell dysfunction and the pathological accumulation of pulmonary artery smooth muscle cells, mesenchymal cells and inflammatory cells in the walls of remodelled small pulmonary vessels, three processes central to the progression of PAH. In particular, it highlights recent developments in targeting the activin signalling pathway, a novel therapeutic approach that shows promise in modulating these pathological processes. The review also addresses the ongoing challenges in translating preclinical findings into effective clinical treatments, emphasising the importance of integrating human data with preclinical models and adopting innovative strategies to bridge the gap between research and clinical practice.","PeriodicalId":9292,"journal":{"name":"Breathe","volume":"21 1","pages":"240116"},"PeriodicalIF":2.3,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11747879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiopulmonary disease.

IF 2.3

Breathe Pub Date : 2025-01-21 eCollection Date: 2025-01-01 DOI: 10.1183/20734735.0291-2024

Imran Sulaiman

引用次数: 0