HSOA journal of addiction & addictive disorders最新文献

{"title":"Buprenorphine/Naloxone and Methadone Opioid Replacement Therapy: A 2-Year Follow-Up Study and Health Economic Analysis","authors":"B. Kidd, Charlotte Renwick, S. Parrott, K. Matthews, A. Baldacchino","doi":"10.24966/AAD-7276/100024","DOIUrl":"https://doi.org/10.24966/AAD-7276/100024","url":null,"abstract":"Background Opioid Replacement Therapy (ORT) is the main UK treatment for opiate dependency. Both methadone and buprenorphine-based drugs are licensed for this purpose in the UK with over 25,000 people prescribed in Scotland, mostly receiving methadone. Choice of ORT agent reflects historic guidance that methadone was the ‘first line’ recommendation if both were suitable. Now, evidence suggests that both are equally effective, although concerns regarding a higher risk of methadone overdose have been raised. Many factors, including higher costs and time commitment to dispense buprenorphine-based products, however, may have affected their wider use in the UK. Clinicians require better evidence to inform their clinical decisions. This study considers a cohort of treatment-seeking opiate-dependent individuals in a single health board area in Scotland, prescribed methadone or buprenorphine/naloxone ORT, comparing 2-year retention rates with the costs of treatment delivery and health care utilization. Methods We compared 62 patients receiving buprenorphine/naloxone (as Suboxone©) with 175 receiving methadone ORT (Total N=237). The health economic component reports only those for whom a complete dataset was available (n=212). Administrative NHS data was used to assess treatment retention and costs over a two year period. Costs included those associated with ORT delivery as well as broader healthcare utilization. Results No statistically significant differences were found with respect to retention rates or healthcare costs though the Cost Effectiveness Plane (CEP) showed considerable uncertainty in these results implying that retention may be greater in the methadone group. Conclusion This study suggests that, when combining all treatment delivery and additional healthcare costs, buprenorphine/naloxone is broadly equivalent in cost effectiveness to methadone ORT when delivered in the NHS system. Retention rates over 2 years were also comparable. These data may support the view that buprenorphine/naloxone represents a cost-neutral alternative ORT to that of methadone.","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44761791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addiction and Evolutionary Process, Common Aspects in Physio-Pathologic Pathways Use Full in Pharmaco-Toxicological Approach","authors":"M. Luisetto","doi":"10.24966/AAD-7276/100021","DOIUrl":"https://doi.org/10.24966/AAD-7276/100021","url":null,"abstract":"Starting from the evolutionary of vertebrates is possible\u0000to verify that mammalians vs reptile in example show a great\u0000characteristic in cooperative behavior, maternal instinct, high\u0000mother depending of progeny and other relevant aspects.","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46638393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthetic Cannabinoids: A Disturbing Trend","authors":"Jeremy D Martinez, Wilshire Blvd Suite","doi":"10.24966/aad-7276/100018","DOIUrl":"https://doi.org/10.24966/aad-7276/100018","url":null,"abstract":"","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44401725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addiction Recovery with Concurring Developmental Disorders","authors":"Hannah Carlson Jurewicz","doi":"10.24966/aad-7276/100019","DOIUrl":"https://doi.org/10.24966/aad-7276/100019","url":null,"abstract":"","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41798554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Alcohol Tax Policy Intervention for Reducing Violent Mortality Rates in Russia","authors":"Y. Razvodovsky","doi":"10.24966/aad-7276/100015","DOIUrl":"https://doi.org/10.24966/aad-7276/100015","url":null,"abstract":"Background: Many experts believe that binge drinking of vodka is the main cause of the strikingly high mortality from external causes in Russia. Objectives: To assess the relationship between alcohol taxes and violent mortality rates in Russia from 2010 to 2015. Methods: Trends in the excise tax rates for vodka and violent mortality rates between 2010 and 2015 were compared. Results: Spearman’s correlation analysis suggests a statistically significant inverse relationship between excise tax rates for vodka and suicides, homicides, accidental drowning, mortality due to exposure to smoke, fire and flames and fatal falls. Conclusions: The results of this study suggest an inverse aggregate-level relationship between excise tax rates for vodka and violent mortality rates in Russia. Given this evidence, raising excise tax rates for vodka appears to be an effective policy to reduce violent mortality rates in Russia.","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48001551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiential Addiction Treatment: Creating Positive Connection through Sociometry and Therapeutic Spiral Model Safety Structures","authors":"Scott Giacomucci","doi":"10.24966/AAD-7276/100017","DOIUrl":"https://doi.org/10.24966/AAD-7276/100017","url":null,"abstract":"","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47211715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Predictive Value of the Central Eight Criminogenic Risk Factors: A Multi-Group Comparison of Dually Diagnosed Violent Offenders with other Subgroups of Violent Offenders","authors":"J. V. Horn, Forensische Zorgspecialisten","doi":"10.24966/AAD-7276/100014","DOIUrl":"https://doi.org/10.24966/AAD-7276/100014","url":null,"abstract":"A dual diagnosis (substance related disorder combined with other clinical and/or personality disorders) is associated with a broad range of adverse outcomes, such as higher suicide risks and criminality. The present study is the first large-scale study aimed at comparing adult violent offenders with a Dual Diagnosis (DD-group, n=710)with other subgroups of adult violent offenders: Offenders without a clinical or personality disorder (No disorders group, n=142); offenders being diagnosed with only Substance Use Disorders (SUD-group, n=120); offenders with other clinical (SUDs excluded) and/or personality disorders (Other disorders group, n=499). Seven of the central eight criminogenic risk factors (categorized in the big and moderate three criminogenic risk factors) described in General Personality and Cognitive Social Learning (GPCSL) theories were included in a multi-group path analysis as predictors of general recidivism and dropout. DD-offenders had the highest recidivism and dropout rates. A few number of the central eight risk factors were found predictive of general recidivism and dropout within each subgroup. In DD-offenders the only risk factor relevant for recidivism was a history of antisocial/criminal behavior.","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45966037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Why are Opioids So Addictive?","authors":"Bernice La France","doi":"10.24966/aad-7276/100016","DOIUrl":"https://doi.org/10.24966/aad-7276/100016","url":null,"abstract":"","PeriodicalId":92903,"journal":{"name":"HSOA journal of addiction & addictive disorders","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48311644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}