Critical care (Houten, Netherlands)最新文献_第7页

Volunteerism during humanitarian crises: a practical guide 人道主义危机中的志愿服务:实用指南

Critical care (Houten, Netherlands) Pub Date : 2022-04-19 DOI: 10.1186/s13054-022-03984-4

H. Bailey, L. Kaplan

引用次数: 3

Transcranial Doppler as a screening test to exclude intracranial hypertension in brain-injured patients: the IMPRESSIT-2 prospective multicenter international study 经颅多普勒筛查排除脑损伤患者颅内高压：IMPRESSIT-2前瞻性多中心国际研究

Critical care (Houten, Netherlands) Pub Date : 2022-04-15 DOI: 10.1186/s13054-022-03978-2

Frank A. Rasulo, S. Calza, C. Robba, F. Taccone, D. Biasucci, R. Badenes, Simone Piva, D. Savo, G. Citerio, J. Dibu, Francesco Curto, Martina Merciadri, Paolo Gritti, P. Fassini, Soojin Park, M. Lamperti, P. Bouzat, Paolo Malacarne, A. Chieregato, R. Bertuetti, R. Aspide, A. Cantoni, V. McCredie, Lucrezia Guadrini, N. Latronico

引用次数: 23

High-flow nasal cannula versus conventional oxygen therapy in acute COPD exacerbation with mild hypercapnia: a multicenter randomized controlled trial 高流量鼻插管与常规氧疗治疗COPD急性加重期轻度高碳酸血症的多中心随机对照试验

Critical care (Houten, Netherlands) Pub Date : 2022-04-15 DOI: 10.1186/s13054-022-03973-7

J. Xia, S. Gu, Wei Lei, Jihua Zhang, Hui Wei, Chaoling Liu, Han Zhang, Rongli Lu, Liqiong Zhang, Mingyan Jiang, Chao Hu, Zhenshun Cheng, Chaojie Wei, Yusheng Chen, Feng-ju Lu, Min Chen, Hong Bi, Hui Liu, C. Yan, H. Teng, Yang Yang, Chen Liang, Yanlei Ge, P. Hou, Jialin Liu, Weiwei Gao, Yi Zhang, Yingying Feng, Cheng Tao, Xu Huang, P. Pan, Hong Luo, Chunmei Yun, Q. Zhan

引用次数: 15

Closed-loop oxygen control improves oxygen therapy in acute hypoxemic respiratory failure patients under high flow nasal oxygen: a randomized cross-over study (the HILOOP study) 高流量鼻吸氧下急性低氧血症性呼吸衰竭患者闭环氧控制改善氧治疗:一项随机交叉研究(HILOOP研究)

Critical care (Houten, Netherlands) Pub Date : 2022-04-14 DOI: 10.1186/s13054-022-03970-w

O. Roca, Oriol Caritg, M. Santafé, Francisco-Javier Ramos, A. Pacheco, M. García-de-Acilu, R. Ferrer, M. Schultz, J. Ricard

引用次数: 4

Serum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes AKI危重患者的血清IL-17水平较高，并与较差的预后相关

Critical care (Houten, Netherlands) Pub Date : 2022-04-14 DOI: 10.1186/s13054-022-03976-4

J. Collett, Victor Ortiz-Soriano, Xilong Li, Alexander H. Flannery, R. Toto, O. Moe, D. Basile, Javier A. Neyra

引用次数: 3

Derivation and performance of an end-of-life practice score aimed at interpreting worldwide treatment-limiting decisions in the critically ill 推导和性能的生命结束实践得分旨在解释世界范围内的治疗限制的决定在危重疾病

Critical care (Houten, Netherlands) Pub Date : 2022-04-13 DOI: 10.1186/s13054-022-03971-9

S. Mentzelopoulos, Su-Chuan Chen, J. Nates, J. Kruser, C. Hartog, A. Michalsen, N. Efstathiou, G. Joynt, S. Lobo, A. Avidan, C. Sprung, Wesley Erwin J. O. Mervyn Charles Victoria Myrick C. John Ely Kompanje Mer Feldman Metaxa Shinall Myburgh Vr, W. Ely, E. Kompanje, M. Mer, C. Feldman, V. Metaxa, Myrick C. Shinall, J. Myburgh, C. Vrettou

引用次数: 3

Gut bacteriobiota and mycobiota are both associated with Day-28 mortality among critically ill patients 肠道菌群和真菌群都与危重病人第28天的死亡率有关

Critical care (Houten, Netherlands) Pub Date : 2022-04-13 DOI: 10.1186/s13054-022-03980-8

R. Prével, R. Enaud, A. Orieux, Adrian Camino, P. Berger, A. Boyer, L. Delhaes, D. Gruson

引用次数: 7

External validation of the 2020 ERC/ESICM prognostication strategy algorithm after cardiac arrest 心脏骤停后2020 ERC/ESICM预测策略算法的外部验证

Critical care (Houten, Netherlands) Pub Date : 2022-04-11 DOI: 10.1186/s13054-022-03954-w

C. Youn, K. Park, S. Kim, B. Lee, T. Cronberg, S. Oh, K. Jeung, I. Cho, S. Choi

引用次数: 12

A novel Vascular Leak Index identifies sepsis patients with a higher risk for in-hospital death and fluid accumulation. 一种新的血管泄漏指数识别脓毒症患者在院内死亡和液体积聚的风险较高

Critical care (Houten, Netherlands) Pub Date : 2022-04-11 DOI: 10.1186/s13054-022-03968-4

Jay Chandra, Miguel A Armengol de la Hoz, Gwendolyn Lee, Alexandria Lee, Patrick Thoral, Paul Elbers, Hyung-Chul Lee, John S Munger, Leo Anthony Celi, David A Kaufman

{"title":"A novel Vascular Leak Index identifies sepsis patients with a higher risk for in-hospital death and fluid accumulation.","authors":"Jay Chandra, Miguel A Armengol de la Hoz, Gwendolyn Lee, Alexandria Lee, Patrick Thoral, Paul Elbers, Hyung-Chul Lee, John S Munger, Leo Anthony Celi, David A Kaufman","doi":"10.1186/s13054-022-03968-4","DOIUrl":"10.1186/s13054-022-03968-4","url":null,"abstract":"Purpose: Sepsis is a leading cause of morbidity and mortality worldwide and is characterized by vascular leak. Treatment for sepsis, specifically intravenous fluids, may worsen deterioration in the context of vascular leak. We therefore sought to quantify vascular leak in sepsis patients to guide fluid resuscitation.Methods: We performed a retrospective cohort study of sepsis patients in four ICU databases in North America, Europe, and Asia. We developed an intuitive vascular leak index (VLI) and explored the relationship between VLI and in-hospital death and fluid balance using generalized additive models (GAM).Results: Using a GAM, we found that increased VLI is associated with an increased risk of in-hospital death. Patients with a VLI in the highest quartile (Q4), across the four datasets, had a 1.61-2.31 times increased odds of dying in the hospital compared to patients with a VLI in the lowest quartile (Q1). VLI Q2 and Q3 were also associated with increased odds of dying. The relationship between VLI, treated as a continuous variable, and in-hospital death and fluid balance was statistically significant in the three datasets with large sample sizes. Specifically, we observed that as VLI increased, there was increase in the risk for in-hospital death and 36-84 h fluid balance.Conclusions: Our VLI identifies groups of patients who may be at higher risk for in-hospital death or for fluid accumulation. This relationship persisted in models developed to control for severity of illness and chronic comorbidities.","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":"103"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42425662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plasma disappearance rate of albumin when infused as a 20% solution. 20%溶液输注时白蛋白的血浆消失率

Critical care (Houten, Netherlands) Pub Date : 2022-04-11 DOI: 10.1186/s13054-022-03979-1

Markus Zdolsek, Patrick Y Wuethrich, Michaela Gunnström, Joachim H Zdolsek, Emma Hasselgren, Christian M Beilstein, Dominique Engel, Robert G Hahn

{"title":"Plasma disappearance rate of albumin when infused as a 20% solution.","authors":"Markus Zdolsek, Patrick Y Wuethrich, Michaela Gunnström, Joachim H Zdolsek, Emma Hasselgren, Christian M Beilstein, Dominique Engel, Robert G Hahn","doi":"10.1186/s13054-022-03979-1","DOIUrl":"10.1186/s13054-022-03979-1","url":null,"abstract":"Background: The transcapillary leakage of albumin is increased by inflammation and major surgery, but whether exogenous albumin also disappears faster is unclear.Methods: An intravenous infusion of 3 mL/kg of 20% albumin was given over 30 min to 70 subjects consisting of 15 healthy volunteers, 15 post-burn patients, 15 patients who underwent surgery with minor bleeding, 10 who underwent surgery with major bleeding (mean, 1.1 L) and 15 postoperative patients. Blood Hb and plasma albumin were measured on 15 occasions over 5 h. The rate of albumin disappearance from the plasma was quantitated with population kinetic methodology and reported as the half-life (T1/2).Results: No differences were observed for T1/2 between volunteers, post-burn patients, patients who underwent surgery with minor bleeding and postoperative patients. The T1/2 averaged 16.2 h, which corresponds to 3.8% of the amount infused per h. Two groups showed plasma concentrations of C-reactive protein of approximately 60 mg/L and still had a similarly long T1/2 for albumin. By contrast, patients undergoing surgery associated with major hemorrhage had a shorter T1/2, corresponding to 15% of the infused albumin per h. In addition, our analyses show that the T1/2 differ greatly depending on whether the calculations consider plasma volume changes and blood losses.Conclusion: The disappearance rate of the albumin in 20% preparations was low in volunteers, in patients with moderately severe inflammation, and in postoperative patients.","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":"104"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45236585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0