Critical care (Houten, Netherlands)最新文献

{"title":"Virtual and augmented reality in critical care medicine: the patient’s, clinician’s, and researcher’s perspective","authors":"R. Bruno, G. Wolff, B. Wernly, M. Masyuk, K. Piayda, S. Leaver, R. Erkens, Daniel Oehler, S. Afzal, H. Heidari, M. Kelm, C. Jung","doi":"10.1186/s13054-022-04202-x","DOIUrl":"https://doi.org/10.1186/s13054-022-04202-x","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41800788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of continuous versus intermittent enteral feeding in critically ill patients: a systematic review and meta-analysis","authors":"A. Heffernan, C. Talekar, M. Henain, L. Purcell, M. Palmer, H. White","doi":"10.1186/s13054-022-04140-8","DOIUrl":"https://doi.org/10.1186/s13054-022-04140-8","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47964810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chest dual-energy CT to assess the effects of steroids on lung function in severe COVID-19 patients","authors":"G. Perchiazzi, Aleksandra Larina, Tomas Hansen, R. Frithiof, M. Hultström, M. Lipcsey, M. Pellegrini","doi":"10.1186/s13054-022-04200-z","DOIUrl":"https://doi.org/10.1186/s13054-022-04200-z","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48801093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wearable ultrasound and provocative hemodynamics: a view of the future","authors":"Jon-Émile S. Kenny, Chelsea E. Munding, A. Eibl, J. Eibl","doi":"10.1186/s13054-022-04206-7","DOIUrl":"https://doi.org/10.1186/s13054-022-04206-7","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47397783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANALYTICAL SINGULAR VALUE DECOMPOSITION FOR A CLASS OF STOICHIOMETRY MATRICES.","authors":"Jacqueline Wentz, Jeffrey C Cameron, David M Bortz","doi":"10.1137/21m1418927","DOIUrl":"10.1137/21m1418927","url":null,"abstract":"<p><p>We present the analytical singular value decomposition of the stoichiometry matrix for a spatially discrete reaction-diffusion system. The motivation for this work is to develop a matrix decomposition that can reveal hidden spatial flux patterns of chemical reactions. We consider a 1D domain with two subregions sharing a single common boundary. Each of the subregions is further partitioned into a finite number of compartments. Chemical reactions can occur within a compartment, whereas diffusion is represented as movement between adjacent compartments. Inspired by biology, we study both (1) the case where the reactions on each side of the boundary are different and only certain species diffuse across the boundary and (2) the case where reactions and diffusion are spatially homogeneous. We write the stoichiometry matrix for these two classes of systems using a Kronecker product formulation. For the first scenario, we apply linear perturbation theory to derive an approximate singular value decomposition in the limit as diffusion becomes much faster than reactions. For the second scenario, we derive an exact analytical singular value decomposition for all relative diffusion and reaction time scales. By writing the stoichiometry matrix using Kronecker products, we show that the singular vectors and values can also be written concisely using Kronecker products. Ultimately, we find that the singular value decomposition of the reaction-diffusion stoichiometry matrix depends on the singular value decompositions of smaller matrices. These smaller matrices represent modified versions of the reaction-only stoichiometry matrices and the analytically known diffusion-only stoichiometry matrix. Lastly, we present the singular value decomposition of the model for the Calvin cycle in cyanobacteria and demonstrate the accuracy of our formulation. The MATLAB code, available at www.github.com/MathBioCU/ReacDiffStoicSVD, provides routines for efficiently calculating the SVD for a given reaction network on a 1D spatial domain.</p>","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":"14 1","pages":"1109-1147"},"PeriodicalIF":1.5,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10795850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87924056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms of lung and diaphragmatic protection by high PEEP in obese COVID-19 ARDS: role of the body mass index","authors":"Joaquín Pérez, J. Dorado, E. Navarro, C. Morais, M. Accoce","doi":"10.1186/s13054-022-04051-8","DOIUrl":"https://doi.org/10.1186/s13054-022-04051-8","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47730813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of the Seraph® 100 Microbind® Affinity Blood Filter to remove bacteria from the blood stream: results of the first in human study","authors":"G. Eden, Julius J Schmidt, S. Büttner, P. Kümpers, C. Hafer, A. Rovas, B. Koch, Bernhard M. W. Schmidt, J. Kielstein","doi":"10.1186/s13054-022-04044-7","DOIUrl":"https://doi.org/10.1186/s13054-022-04044-7","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49493105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert clinical pharmacological advice may make an antimicrobial TDM program for emerging candidates more clinically useful in tailoring therapy of critically ill patients","authors":"Milo Gatti, P. Cojutti, M. Bartoletti, T. Tonetti, Amedeo Bianchini, S. Ramirez, G. Pizzilli, S. Ambretti, M. Giannella, R. Mancini, A. Siniscalchi, P. Viale, F. Pea","doi":"10.1186/s13054-022-04050-9","DOIUrl":"https://doi.org/10.1186/s13054-022-04050-9","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47505335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The sit-to-stand test as a patient-centered functional outcome for critical care research: a pooled analysis of five international rehabilitation studies.","authors":"Heather K O'Grady, Lara Edbrooke, Christopher Farley, Sue Berney, Linda Denehy, Zudin Puthucheary, Michelle E Kho","doi":"10.1186/s13054-022-04048-3","DOIUrl":"10.1186/s13054-022-04048-3","url":null,"abstract":"<p><strong>Background: </strong>With ICU mortality rates decreasing, it is increasingly important to identify interventions to minimize functional impairments and improve outcomes for survivors. Simultaneously, we must identify robust patient-centered functional outcomes for our trials. Our objective was to investigate the clinimetric properties of a progression of three outcome measures, from strength to function.</p><p><strong>Methods: </strong>Adults (≥ 18 years) enrolled in five international ICU rehabilitation studies. Participants required ICU admission were mechanically ventilated and previously independent. Outcomes included two components of the Physical Function in ICU Test-scored (PFIT-s): knee extensor strength and assistance required to move from sit to stand (STS); the 30-s STS (30 s STS) test was the third outcome. We analyzed survivors at ICU and hospital discharge. We report participant demographics, baseline characteristics, and outcome data using descriptive statistics. Floor effects represented ≥ 15% of participants with minimum score and ceiling effects ≥ 15% with maximum score. We calculated the overall group difference score (hospital discharge score minus ICU discharge) for participants with paired assessments.</p><p><strong>Results: </strong>Of 451 participants, most were male (n = 278, 61.6%) with a median age between 60 and 66 years, a mean APACHE II score between 19 and 24, a median duration of mechanical ventilation between 4 and 8 days, ICU length of stay (LOS) between 7 and 11 days, and hospital LOS between 22 and 31 days. For knee extension, we observed a ceiling effect in 48.5% (160/330) of participants at ICU discharge and in 74.7% (115/154) at hospital discharge; the median [1st, 3rd quartile] PFIT-s difference score (n = 139) was 0 [0,1] (p < 0.05). For STS assistance, we observed a ceiling effect in 45.9% (150/327) at ICU discharge and in 77.5% (79/102) at hospital discharge; the median PFIT-s difference score (n = 87) was 1 [0, 2] (p < 0.05). For 30 s STS, we observed a floor effect in 15.0% (12/80) at ICU discharge but did not observe a floor or ceiling effect at hospital discharge. The median 30 s STS difference score (n = 54) was 3 [1, 6] (p < 0.05).</p><p><strong>Conclusion: </strong>Among three progressive outcome measures evaluated in this study, the 30 s STS test appears to have the most favorable clinimetric properties to assess function at ICU and hospital discharge in moderate to severely ill participants.</p>","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":"175"},"PeriodicalIF":0.0,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9195216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44760945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to “Hyperoxemia in postsurgical sepsis/septic shock patients is associated with reduced mortality”","authors":"M. Martín-Fernández, M. Heredia-Rodríguez, E. Tamayo","doi":"10.1186/s13054-022-04045-6","DOIUrl":"https://doi.org/10.1186/s13054-022-04045-6","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49293877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}