{"title":"Accuracy of heparin-binding protein for the diagnosis of nosocomial meningitis and ventriculitis","authors":"Yu-Chin Kong, Yinjiao Ye, Jia-wei Ma, G. Shi","doi":"10.1186/s13054-022-03929-x","DOIUrl":"https://doi.org/10.1186/s13054-022-03929-x","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41456998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kirstine N la Cour, Nina C Andersen-Ranberg, Sarah Weihe, Lone M Poulsen, Camilla B Mortensen, Cilia K W Kjer, Marie O Collet, Stine Estrup, Ole Mathiesen
{"title":"Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review.","authors":"Kirstine N la Cour, Nina C Andersen-Ranberg, Sarah Weihe, Lone M Poulsen, Camilla B Mortensen, Cilia K W Kjer, Marie O Collet, Stine Estrup, Ole Mathiesen","doi":"10.1186/s13054-022-03931-3","DOIUrl":"10.1186/s13054-022-03931-3","url":null,"abstract":"<p><strong>Background: </strong>Delirium is the most common cerebral dysfunction in the intensive care unit (ICU) and can be subdivided into a hypoactive, hyperactive, or mixed motor subtype based on the clinical manifestation. The aim of this review was to describe the distribution, pharmacological interventions, and outcomes of delirium motor subtypes in ICU patients.</p><p><strong>Methods: </strong>This systematic scoping review was performed according to the PRISMA-ScR and Cochrane guidelines. We performed a systematic search in six major databases to identify relevant studies. A meta-regression analysis was performed where pooled estimates with 95% confidence intervals were computed by a random effect model.</p><p><strong>Results: </strong>We included 131 studies comprising 13,902 delirious patients. There was a large between-study heterogeneity among studies, including differences in study design, setting, population, and outcome reporting. Hypoactive delirium was the most prevalent delirium motor subtype (50.3% [95% CI 46.0-54.7]), followed by mixed delirium (27.7% [95% CI 24.1-31.3]) and hyperactive delirium (22.7% [95% CI 19.0-26.5]). When comparing the delirium motor subtypes, patients with mixed delirium experienced the longest delirium duration, ICU and hospital length of stay, the highest ICU and hospital mortality, and more frequently received administration of specific agents (antipsychotics, α2-agonists, benzodiazepines, and propofol) during ICU stay. In studies with high average age for delirious patients (> 65 years), patients were more likely to experience hypoactive delirium.</p><p><strong>Conclusions: </strong>Hypoactive delirium was the most prevalent motor subtype in critically ill patients. Mixed delirium had the worst outcomes in terms of delirium duration, length of stay, and mortality, and received more pharmacological interventions compared to other delirium motor subtypes. Few studies contributed to secondary outcomes; hence, these results should be interpreted with care. The large between-study heterogeneity suggests that a more standardized methodology in delirium research is warranted.</p>","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":"53"},"PeriodicalIF":0.0,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43361878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Kooistra, A. E. Van Herwaarden, J. Gerretsen, R. L. Smeets, S. van der Velde, M. V. D. Van Den Berg, J. G. van der Hoeven, M. Kox, P. Pickkers
{"title":"41st International Symposium on Intensive Care and Emergency Medicine","authors":"E. Kooistra, A. E. Van Herwaarden, J. Gerretsen, R. L. Smeets, S. van der Velde, M. V. D. Van Den Berg, J. G. van der Hoeven, M. Kox, P. Pickkers","doi":"10.1186/s13054-022-03927-z","DOIUrl":"https://doi.org/10.1186/s13054-022-03927-z","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65772277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Rüddel, D. Thomas-Rüddel, K. Reinhart, F. Bach, H. Gerlach, Matthias Lindner, J. Marshall, P. Simon, M. Weiss, F. Bloos, D. Schwarzkopf, Gernot Achim Tobias Heike Gunther Annett Steffen Christia Marx Schindler Schürholz Schlegel‑Höfner Lehmann S, G. Marx, Achim Schindler, T. Schürholz, Heike Schlegel‑Höfner, Gunther Lehmann, A. Sander, Steffen Friese, Christian Scholz, P. Fischer, C. Fuchs, L. Becher, Norbert Salewsky, T. Schreiber, A. Goldmann, D. Keh, K. Schmid, Winfried Menning, R. Steuckart, R. Barz, K. Dey, Meike Fahrenholz, Martin Müller, H. Gerlach, S. Toussaint, J. Brederlau, F. Bach, D. Buschmann, I. Gummelt, J. Hoeschen, M. Klaproth, I. Vedder, Ulrike Bachmann‑Holdau, J. Eiche, Rolf Hauschild, M. Lange, Davia Herrmann‑Karbaum, A. Lubasch, M. Rücker, C. Icke, Alexander Lucht, A. Meier‑Hellmann, Jan Wagner, Olaf Arnold, Steffen Kästner, T. Clausen, Michael Sternkopf, R. Voswinckel, T. Benndorf, Christel Eiserloh, G. Kuhnle, M. Koch, M. Gerber, M. Gründling, Liane Guderian, S. Kuhn, C. Scheer, G
{"title":"Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial","authors":"H. Rüddel, D. Thomas-Rüddel, K. Reinhart, F. Bach, H. Gerlach, Matthias Lindner, J. Marshall, P. Simon, M. Weiss, F. Bloos, D. Schwarzkopf, Gernot Achim Tobias Heike Gunther Annett Steffen Christia Marx Schindler Schürholz Schlegel‑Höfner Lehmann S, G. Marx, Achim Schindler, T. Schürholz, Heike Schlegel‑Höfner, Gunther Lehmann, A. Sander, Steffen Friese, Christian Scholz, P. Fischer, C. Fuchs, L. Becher, Norbert Salewsky, T. Schreiber, A. Goldmann, D. Keh, K. Schmid, Winfried Menning, R. Steuckart, R. Barz, K. Dey, Meike Fahrenholz, Martin Müller, H. Gerlach, S. Toussaint, J. Brederlau, F. Bach, D. Buschmann, I. Gummelt, J. Hoeschen, M. Klaproth, I. Vedder, Ulrike Bachmann‑Holdau, J. Eiche, Rolf Hauschild, M. Lange, Davia Herrmann‑Karbaum, A. Lubasch, M. Rücker, C. Icke, Alexander Lucht, A. Meier‑Hellmann, Jan Wagner, Olaf Arnold, Steffen Kästner, T. Clausen, Michael Sternkopf, R. Voswinckel, T. Benndorf, Christel Eiserloh, G. Kuhnle, M. Koch, M. Gerber, M. Gründling, Liane Guderian, S. Kuhn, C. Scheer, G","doi":"10.1186/s13054-022-03901-9","DOIUrl":"https://doi.org/10.1186/s13054-022-03901-9","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42463298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. McPeake, P. Henderson, P. Mactavish, H. Devine, M. Daniel, Phil Lucie, Lynn Bollan, Lucy A Hogg, M. MacMahon, S. Mulhern, P. Murray, Laura O’Neill, L. Strachan, T. Iwashyna, M. Shaw, T. Quasim
{"title":"A multicentre evaluation exploring the impact of an integrated health and social care intervention for the caregivers of ICU survivors","authors":"J. McPeake, P. Henderson, P. Mactavish, H. Devine, M. Daniel, Phil Lucie, Lynn Bollan, Lucy A Hogg, M. MacMahon, S. Mulhern, P. Murray, Laura O’Neill, L. Strachan, T. Iwashyna, M. Shaw, T. Quasim","doi":"10.1186/s13054-022-04014-z","DOIUrl":"https://doi.org/10.1186/s13054-022-04014-z","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42110204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Matějovič, O. Huet, K. Dams, G. Elke, C. Vaquerizo Alonso, Á. Csomós, Ł. Krzych, R. Tetamo, Z. Puthucheary, O. Rooyackers, I. Tjäder, H. Kuechenhoff, W. Hartl, M. Hiesmayr
{"title":"Medical nutrition therapy and clinical outcomes in critically ill adults: a European multinational, prospective observational cohort study (EuroPN)","authors":"M. Matějovič, O. Huet, K. Dams, G. Elke, C. Vaquerizo Alonso, Á. Csomós, Ł. Krzych, R. Tetamo, Z. Puthucheary, O. Rooyackers, I. Tjäder, H. Kuechenhoff, W. Hartl, M. Hiesmayr","doi":"10.1186/s13054-022-03997-z","DOIUrl":"https://doi.org/10.1186/s13054-022-03997-z","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48449943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The physiological foundations of critical care medicine: the contribution of Joseph Milic-Emili, a physiologist “by hook or by crook”","authors":"V. Ranieri, C. Guérin","doi":"10.1186/s13054-022-03919-z","DOIUrl":"https://doi.org/10.1186/s13054-022-03919-z","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44458789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nina Rittgerodt, T. Pape, M. Busch, L. Becker, A. Schneider, H. Wedemeyer, B. Seeliger, Julius J Schmidt, A. Hunkemöller, J. Fuge, W. Knitsch, C. Fegbeutel, Hans-Jörg Gillmann, B. Meyer, M. Hoeper, J. Hinrichs, S. David, K. Stahl
{"title":"Predictors of response to intra-arterial vasodilatory therapy of non-occlusive mesenteric ischemia in patients with severe shock: results from a prospective observational study","authors":"Nina Rittgerodt, T. Pape, M. Busch, L. Becker, A. Schneider, H. Wedemeyer, B. Seeliger, Julius J Schmidt, A. Hunkemöller, J. Fuge, W. Knitsch, C. Fegbeutel, Hans-Jörg Gillmann, B. Meyer, M. Hoeper, J. Hinrichs, S. David, K. Stahl","doi":"10.1186/s13054-022-03962-w","DOIUrl":"https://doi.org/10.1186/s13054-022-03962-w","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49162086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Hongo, Ryohei Yamamoto, Keibun Liu, Takahiko Yaguchi, Hisashi Dote, Ryusuke Saito, T. Masuyama, Kosuke Nakatsuka, S. Watanabe, Takahiro Kanaya, Tomoya Yamaguchi, T. Yumoto, H. Naito, A. Nakao
{"title":"Association between timing of speech and language therapy initiation and outcomes among post-extubation dysphagia patients: a multicenter retrospective cohort study","authors":"T. Hongo, Ryohei Yamamoto, Keibun Liu, Takahiko Yaguchi, Hisashi Dote, Ryusuke Saito, T. Masuyama, Kosuke Nakatsuka, S. Watanabe, Takahiro Kanaya, Tomoya Yamaguchi, T. Yumoto, H. Naito, A. Nakao","doi":"10.1186/s13054-022-03974-6","DOIUrl":"https://doi.org/10.1186/s13054-022-03974-6","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43483546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}