Spora : a journal of biomathematics最新文献_第2页

Hepatitis B and D: A Forecast on Actions Needed to Reduce Incidence and Achieve Elimination 乙型肝炎和丁型肝炎:减少发病率和实现消除所需行动的预测

Spora : a journal of biomathematics Pub Date : 2022-01-01 DOI: 10.30707/spora8.1.1652717156.650087

引用次数: 0

Fostering Research and Education in Mathematical Biology 促进数学生物学的研究和教育

Spora : a journal of biomathematics Pub Date : 2021-01-01 DOI: 10.30707/spora7.1.1624911489.532904

E. Board

引用次数: 0

A Study of COVID-19 Mortality Under Varying Patient Frailty 不同患者虚弱程度下COVID-19死亡率的研究

Spora : a journal of biomathematics Pub Date : 2021-01-01 DOI: 10.30707/etd2020.1606247535.296021ah

Alison Sifuentes

引用次数: 0

A Milestone for Spora Spora的里程碑

Spora : a journal of biomathematics Pub Date : 2020-01-01 DOI: 10.30707/spora6.1/bpjf8019

引用次数: 0

Modeling Neural Behavior and Pain During Bladder Distention using an Agent-based Model of the Central Nucleus of the Amygdala. 用基于主体的杏仁核中央核模型模拟膀胱膨胀时的神经行为和疼痛。

Spora : a journal of biomathematics Pub Date : 2019-01-01

Joshua Baktay, Rachael Miller Neilan, Marissa Behun, Neal McQuaid, Benedict Kolber

{"title":"Modeling Neural Behavior and Pain During Bladder Distention using an Agent-based Model of the Central Nucleus of the Amygdala.","authors":"Joshua Baktay, Rachael Miller Neilan, Marissa Behun, Neal McQuaid, Benedict Kolber","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic bladder pain evokes asymmetric behavior in neurons across the left and right hemispheres of the amygdala. An agent-based computational model was created to simulate the firing of neurons over time and in response to painful bladder stimulation. Each agent represents one neuron and is characterized by its location in the amygdala and response type (excited or inhibited). At each time step, the firing rates (Hz) of all neurons are stochastically updated from probability distributions estimated from data collected in laboratory experiments. A damage accumulation model tracks the damage accrued by neurons during long-term, painful bladder stimulation. Emergent model output uses neural activity to measure temporal changes in pain attributed to bladder stimulation. Simulations demonstrate the model's ability to capture acute and chronic pain and its potential to predict changes in pain similar to those observed in the lab. Asymmetric neural activity during the progression of chronic pain is examined using model output and a sensitivity analysis.</p>","PeriodicalId":92725,"journal":{"name":"Spora : a journal of biomathematics","volume":"5 ","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380509/pdf/nihms-1005670.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36988903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combating Tuberculosis: Using Time-Dependent Sensitivity Analysis to Develop Strategies for Treatment and Prevention 与结核病作斗争:利用时变敏感性分析制定治疗和预防策略

Spora : a journal of biomathematics Pub Date : 2019-01-01 DOI: 10.30707/SPORA5.1CLARK

Kendall B. Clark, Mayleen Cortez, C. Hernández, B. E. Thomas, Allison L. Lewis

引用次数: 1

Analysis of an agent-based model for predicting the behavior of bighead carp (Hypophthalmichthys nobilis) under the influence of acoustic deterrence 基于智能体的高头鱼在声阻作用下的行为预测模型分析

Spora : a journal of biomathematics Pub Date : 2019-01-01 DOI: 10.30707/spora5.1/loxa2051

Craig Garzella, J. Gaudy, Karl R. B. Schmitt, A. Mansuri

{"title":"Analysis of an agent-based model for predicting the behavior of bighead carp (Hypophthalmichthys nobilis) under the influence of acoustic deterrence","authors":"Craig Garzella, J. Gaudy, Karl R. B. Schmitt, A. Mansuri","doi":"10.30707/spora5.1/loxa2051","DOIUrl":"https://doi.org/10.30707/spora5.1/loxa2051","url":null,"abstract":"Bighead carp (Hypophthalmichthys nobilis) are an invasive, voracious, highly fecund species threatening the ecological integrity of the Great Lakes. This agent-based model and analysis explore bighead carp behavior in response to acoustic deterrence in an effort to discover properties that increase likelihood of deterrence system failure. Results indicate the most significant (p < 0.05) influences on barrier failure are the quantity of detritus and plankton behind the barrier, total number of bighead carp successfully deterred by the barrier, and number of native fishes freely moving throughout the simulation. Quantity of resources behind the barrier influence bighead carp to penetrate when populations are resource deprived. When native fish populations are low, an accumulation of phytoplankton can occur, increasing the likelihood of an algal bloom occurrence. Findings of this simulation suggest successful implementation with proper maintenance of an acoustic deterrence system has potential of abating the threat of bighead carp on ecological integrity of the Great Lakes.","PeriodicalId":92725,"journal":{"name":"Spora : a journal of biomathematics","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80628872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Dynamical System Model of Dengue Transmission for Rio de Janeiro, Brazil 巴西里约热内卢登革热传播的动力系统模型

Spora : a journal of biomathematics Pub Date : 1900-01-01 DOI: 10.30707/spora9.1.1675492827.528788

Gregory Schmidt, Benjamin Whipple, V. Chellamuthu, Xiaoxia Xie

引用次数: 0