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FEATURES OF THE CERVICAL AREA STRUCTURE OF PERMANENT TEETH OF DIFFERENT GROUPS 不同群体恒牙颈区结构特征
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.3
Z. Masna, D. Yakymovych
{"title":"FEATURES OF THE CERVICAL AREA STRUCTURE OF PERMANENT TEETH OF DIFFERENT GROUPS","authors":"Z. Masna, D. Yakymovych","doi":"10.24061/2413-0737.27.1.105.2023.3","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.3","url":null,"abstract":"According to the findings of various authors, almost 100% of the world's population suffers from dental caries. Carious lesions of the cervical area of the teeth attract special attention since their localization does not provide for the early detection of the pathological process, and the features of the microbiocenosis of the oral cavity and the structural features of the enamel-cementum-dentine junction are significant risk factors for the development and progression of cervical caries. The aim of the study is to research different options of the cervical area structure of teeth of different groups and to find out the frequency of their occurrence. Material and methods. We determined the ratio of the hard tissues – enamel, cementum and dentin – in the cervical area of 320 permanent teeth of the maxilla and mandible (10 teeth each of 11-18, 21-28, 31-38 and 41-48), which were removed due to clinical indications in their vestibular, oral (palatal/lingual), medial and distal contact surfaces. Results. Four options of the hard tissue ratio in the cervical region of the tooth were identified: lack of contact between enamel and cementum and the presence of zones of open dentin; contact of the enamel margin with the cementum; enamel overlapping cementum; cementum overlapping enamel. Each of the specified options occurs with different frequency on the vestibular, oral, medial and distal contact surfaces of teeth of different groups. Among all examined tooth surfaces, 2% have a zone of exposed dentin in the cervical area, 4% have the enamel in the cervical area covered with a layer of cementum, 47% of the surfaces have variants of contact of enamel margin with cementum and overlapping of cementum with a layer of enamel. Further study of the characteristics of the ratio of the hard tissues of the tooth in the cervical area will allow to find out the etiological factors of the development of cervical lesions and offer new and improved methods of their prevention, diagnosis and treatment.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86859896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FREQUENCY OF ACUTE HEART FAILURE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AFTER REVASCULARIZATION 急性心肌梗死患者血运重建术后急性心力衰竭的发生率
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.6
A. Solomonchuk
{"title":"FREQUENCY OF ACUTE HEART FAILURE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AFTER REVASCULARIZATION","authors":"A. Solomonchuk","doi":"10.24061/2413-0737.27.1.105.2023.6","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.6","url":null,"abstract":"Aim – to study the frequency of acute heart failure (AHF) in patients with Q-myocardial infarction (MI), to establish the clinical and functional features of the course and risk factors for high-grade heart failure in patients with Q-MI.Materials and methods. The data of 308 middle-aged Q-MI patients (62.9±0.6) years old, including 215 men (69.8%) and 93 women (30.2%), who were treated in a specialized cardiology department, were analyzed. Among the examined patients, an analysis of the combination of Q-MI with AHF of different classes according to Killip was performed. All patients underwent a general clinical examination, ECG, echocardiography and lung ultrasound, coronary ventriculography, additional laboratory examination (quantitative troponin I, D-dimer, CPK-MV, CRP, NT-proBNP). Statistical analysis of the results was performed in the \"Statistica 7.0\" system. The results. Among all examined, 161 (52.3%) persons had AHF class I according to Killip, 44 (14.3%) – class II, 55 (17.8%) – class III, and 48 (15.6%) patients - class IV. When dividing by age and sex, no significant difference was found between different classes of AHF. Men predominated in all groups - from 61.8% in the group of MI+AHF of class III to 73.3% in the group of MI+AHF of class I. In all groups the majority of those examined were patients who were hospitalized within 2 to 6 hours of the onset of the pain syndrome - 63.4% in group I, 45.4% in group II, 49.1% in group III, and 56.2% in group IV. Hospitalized within 6-12 hours among all MI patients was 19.2%, slightly more in groups of AHF I and II (20.5% and 22.7%) than in groups III and IV (16.4% and 14, 7%), (р=0.34). The smallest part of patients - 7.2% - was hospitalized within more than 12 hours from the onset of the pain syndrome, from 3.7% in the group of MI and AHF I to 12.7% in the group of AHF III (p=0.32). The average BMI was (29.6±0.3) kg/m2, the highest BMI was determined in the group of MI and GOS AHF – (30.5±0.4) kg/m2, the lowest – in the group of MI and AHF I – (29 .1±0.4) kg/m2 (р=0.24). Arterial hypertension (AH) among persons with AHF I occurred in 85.1% of cases, with AHF II - in 100%, in the group of AHF III - in 90.9%, in AHF IV - in 89.6% (р=0,66). When comparing the data of patients with MI and AHF of high degrees - Killip III-IV (group II) it was found that they were significantly older than people with MI without signs of AHF of high gradations (p=0.016). It was found that patients with MI and high-grade heart failure differed from people with class I-II heart failure by higher BMI - (30.4±0.5) versus (29.1±0.2) kg/m2, respectively (p=0.046), as well as a longer history of hypertension - 52.4% of patients in group II had hypertension for more than 10 years, while in group I - 36.1% (p=0.006). There is a significantly higher frequency of all forms of atrial fibrillation (AF) in the anamnesis in patients with high-grade heart failure - 12.6% versus 3.9% in group I (p=0.0004) and a higher frequency of","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84480714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE IMPACT OF QUARANTINE AND SOCIAL ISOLATION ON THE MENTAL STATE OF THE POPULATION 隔离和社会隔离对人口精神状态的影响
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.12
T. Ivanitska
{"title":"THE IMPACT OF QUARANTINE AND SOCIAL ISOLATION ON THE MENTAL STATE OF THE POPULATION","authors":"T. Ivanitska","doi":"10.24061/2413-0737.27.1.105.2023.12","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.12","url":null,"abstract":"The COVID-19 pandemic has led to an unprecedented crisis in mental health worldwide. Most of the affected countries, including Ukraine, have implemented physical distancing. Despite the efforts of many scientists over the past few months, research into the negative psychological effects of social isolation is still ongoing, and many questions remain unanswered.Purpose. To examine the data of scientific research on the impact of quarantine and social isolation on the mental state of the population.Materials and methods. In our search of the available literature, we identified 129 articles on the impact of the pandemic on mental health published between May 2020 and May 2022, and this review analyzes thirty-two articles (in this time range). In addition, data from six fundamental studies on loneliness and social isolation were used.Results. The 2019 coronavirus disease pandemic has affected the mental health of people around the world. The scientific publications we reviewed suggest that this large-scale health crisis has led to an increase in the prevalence of symptoms of anxiety, depression, and PTSD. According to the World Health Organization, the prevalence of conditions such as depression and anxiety increased by more than 25% in the first year of the COVID-19 pandemic. Research also suggests that measures to limit the spread of the disease (including physical distancing, quarantine, and isolation) can increase feelings of loneliness and withdrawal symptoms.Conclusions. The impact of the COVID-19 pandemic on mental health is unprecedented in its scale. Most notably, during the time period covered by this literature review, serious mental disorders were observed in the general population, with a particularly high risk among people with prior mental illness.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"561 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77189587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MICRO- AND ULTRAMICROSCOPIC STRUCTURE OF THE LEFT ATRIA-VENTRICULAR VALVULAR APPARATUS IN HUMAN AT THE MATURE AGE IN NORM 正常成人左房室瓣膜的显微及超微结构
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.5
T. Semeniuk, Y. Malyk, N. Pentelejchuk, A. Khodorovska
{"title":"MICRO- AND ULTRAMICROSCOPIC STRUCTURE OF THE LEFT ATRIA-VENTRICULAR VALVULAR APPARATUS IN HUMAN AT THE MATURE AGE IN NORM","authors":"T. Semeniuk, Y. Malyk, N. Pentelejchuk, A. Khodorovska","doi":"10.24061/2413-0737.27.1.105.2023.5","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.5","url":null,"abstract":"This article presents the morphological characteristics of the mitral valve of a normal heart of an adult at a mature age.The purpose of our investigation is to find out the peculiarities of the morphology of the structural components of the mitral valve apparatus of the heart of a person of mature age in the norm.Material and methods. The study was performed on 32 preparations of mitral valves of adult human hearts. A complex of morphological research methods was used: methods of light and electron microscopy, histochemical method.Results. With the use of a complex of morphological research methods, a study of the structural components of the mitral valve apparatus of a normal mature person was carried out and their histoarchitectonics was established at the micro- and sub-microscopic levels.Conclusions. The leaflets of the mitral valve are connective tissue plates covered with a single-layer flat epithelium - endothelium. The leaflets are formed by fibrous connective tissue of different density, as a result of which three layers are identified: spongy, fibrous and ventricular. Typical chordae tendineae in the form of connective tissue threads extend from the papillary muscles to the leaflets of the mitral valve and attach to their ventricular surface. The skeleton of chordae tendinea is formed by dense fibrous connective tissue. Striated cardiac muscle tissue is found in some chordae tendinea in the areas on the side of the papillary muscles. The papillary muscles are formed by the working fibers of cardiomyocytes, which form a kind of network due to branches and anastomoses. The working fibers of cardiomyocytes are accompanied by layers of loose fibrous connective tissue, which includes a large number of blood vessels.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84738632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE FEATURES OF THE MORPHOLOGY OF THE UTERUS OF EARLY FETUSES 早期胎儿子宫的形态特征
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.4
V. V. Melnyk, V. Kryvetskyi, D. Proniaiev, O.P. Аntoniuk
{"title":"THE FEATURES OF THE MORPHOLOGY OF THE UTERUS OF EARLY FETUSES","authors":"V. V. Melnyk, V. Kryvetskyi, D. Proniaiev, O.P. Аntoniuk","doi":"10.24061/2413-0737.27.1.105.2023.4","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.4","url":null,"abstract":"Perinatal changes in the shape of the uterus were traced, and a certain shape of its bottom was determined in each of the months of the perinatal period of development. Material and methods. Features of the typical and variant anatomy of the uterus, vagina, ovaries and fallopian tubes were studied on 160 preparations of fetuses and newborns using a complex of morphological research methods: macroscopic, ordinary and thin dissection.Research results. It has been proven that the topography of the bottom of the uterus is characterized by the greatest variability of shape, which can be grooved, bumpy, flat and convex. The physiological disappearance of the groove on the uterus was observed, which is confirmed by established reliable correlations of average strength between the width of the uterine fundus, the indicators of which vary from 6.0±0.21 mm to 6.4±1.60 mm and the parietal-p fetal length (TPD) of the fetus.Conclusions. As a result of morphological studies, the following forms of the uterine fundus were established: grooved, tuberous, flat and convex. In our opinion, this (in the specified sequence) is the natural phase of the transformation of the shape of the bottom of the uterus during the perinatal period.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90490143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RESULTS OF MEDICAL INTERACTION ANALYSIS EMPLOYEES WITH MASS INFORMATION MEDIA (FROM CLAIMS TO UNDERSTANDING) 员工与大众信息媒体医疗互动分析结果(从主张到理解)
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.9
A. Biduchak, N. Hopko, V. Gorachuk
{"title":"RESULTS OF MEDICAL INTERACTION ANALYSIS EMPLOYEES WITH MASS INFORMATION MEDIA (FROM CLAIMS TO UNDERSTANDING)","authors":"A. Biduchak, N. Hopko, V. Gorachuk","doi":"10.24061/2413-0737.27.1.105.2023.9","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.9","url":null,"abstract":"The mass media is neither an instrument of destruction nor an instrument of progress. Their positive or negative consequences depend on which social forces are used and for what. The power of mass media is manifested in the ability to create one or another image of a medical organization, which can be destroyed by a small detail that even medical experts do not see.The ability to communicate with the patient is one of the most valuable qualities of any medical worker, it depends on the effectiveness of the treatment and diagnostic process, the patient's satisfaction with the help provided to him and the patient's assessment of the professionalism of medical specialists.The purpose of the study is to analyze the occurrence of conflict situations during the interaction of medical workers with mass media.Materials and methods. The research used methods characteristic of medical science: dialectical, systemic-structural approach and content analysis, which made it possible to analyze the legal reality of the conflict between medical workers and the mass media.Results and discussion. It was established that in case of conflict situations between the doctor and the mass media, it is necessary to follow certain tactics. Dialogue with media representatives is built taking into account medical confidentiality. It is important to inform journalists that the law provides limited opportunities for a doctor to provide information without the patient's consent. If a journalist is interested in a specific patient and a media representative asks to provide information about this patient, then before providing such information, the medical professional must talk to the patient and find out whether he agrees to provide information about his health or other information that known to employees of the medical organization.Conclusion. On the basis of the conducted research, it was established that the conflict in the implementation of medical activity and the coverage of its problems by means of mass information is a dynamic process, and its existence means the need to study the prerequisites for its occurrence in medical activity, the nature of the conflict situation itself and the content of the conflict in order to prevent its likelihood or weaken it possible negative consequences.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90821872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE LEVEL OF ZINC IN BLOOD PLASMA AND THE COURSE OF GALLSTONE DISEASE IN CHILDREN 儿童血浆锌水平与胆结石病程的关系
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.11
T. Sorokman, V. Ostapchuk
{"title":"THE LEVEL OF ZINC IN BLOOD PLASMA AND THE COURSE OF GALLSTONE DISEASE IN CHILDREN","authors":"T. Sorokman, V. Ostapchuk","doi":"10.24061/2413-0737.27.1.105.2023.11","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.11","url":null,"abstract":"Determining the zinc level in children's blood plasma is an urgent problem, given its possible participation in the formation of cholelithiasis.Aim. To investigate the level of zinc in the blood plasma and the clinical course of gallstone disease (GSD) in children.Methods. 69 children aged 10-17 years and 25 children without biliary tract pathology were selected by the method of simple randomization. Verification of the diagnosis was carried out by applying dynamic ultrasound examination and X-ray examination of the organs of the abdominal cavity. Quantitative determination of zinc in blood plasma was carried out using mass spectrometry.Results. Dysfunction of the biliary tract according to the hyperkinetic type occurred in 55.1±7.1% of children and according to the hypokinetic type in 44.9±3.9%. The asymptomatic variant of housing and communal services was observed in 23.9%, painful - in 54.3% of patients, paroxysmal - in 21.7% of patients. The plasma concentration of zinc in children with gastrointestinal diseases was 1.87 times lower than in children of the comparison group and 1.37 times lower than in children with hyperkinetic gallbladder dysfunction, while there was a probable difference between these indicators in children with housing and communal services and in children with the hypotonic type of gallbladder dysfunction (p<0.05).Conclusions. 1. The leading syndromes of gallstone disease in children were pain and dyspepsia. 2. Gallstone disease in children occurs against the background of gallbladder dysfunction with a predominance of the painful course, the formation of solitary bilirubin-derived concretions and minor changes in biochemical blood analysis. 3. The concentration of zinc in the blood plasma of children with gallstone disease is probably lower than in children of the comparison group and does not depend on age and gender.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89229399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ROLE OF CRITICAL THINKING IN IMPROVING THE TEACHING OF FUNDAMENTAL THEORETICAL AND CLINICAL DISCIPLINES 批判性思维在提高基础理论和临床学科教学中的作用
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.15
Y. Rohovyi, O. Bilo’okiy, V. Bilo’okiy
{"title":"THE ROLE OF CRITICAL THINKING IN IMPROVING THE TEACHING OF FUNDAMENTAL THEORETICAL AND CLINICAL DISCIPLINES","authors":"Y. Rohovyi, O. Bilo’okiy, V. Bilo’okiy","doi":"10.24061/2413-0737.27.1.105.2023.15","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.15","url":null,"abstract":"Relevance. It is known that critical thinking is a system of judgments, which is used to analyze facts, phenomena, events and draw reasonable conclusions. Critical thinking allows you to formulate assessments, interpretations, correctly apply the obtained results to situations and problems. Critical thinking is learning the ability to reason. Critical thinking is thinking about thinking, when a person reflects in order to improve their thinking.Objective. Defend the point of view that the introduction of critical thinking technologies into the educational process will contribute to the improvement of the training of specialists in the medical field with a significant enhancement in the quality of teaching fundamental theoretical and clinical disciplines.Material and methods. We analyzed the improvement of the quality of teaching of fundamental theoretical and clinical disciplines with the help of the introduction of critical thinking technologies: lotus flower, Edward de Bono's six hats, fishbone, brainstorming, intellectual maps.Results. Proposed technologies of critical thinking \"Lotus flower\" is a technique that involves finding a solution to a problem in eight directions, develops creative abilities of students; brainstorming - an operational method of problem solving based on stimulating the creative activity of students; the \"fishbone\" technique in the \"head\" of the skeleton students mark the problem under consideration, on the upper bones the causes of the problem under study are noted, on the lower bones during the reading they write facts that confirm the existence of the stated reasons, in the \"tail\" there is a conclusion on the researched issue; intelligence maps (mind maps, mental maps, \"mind maps\", memory maps) - a way of visual presentation of any structured information, a form of graphic expression; Edward de Bono's six thinking hats - the idea of parallel thinking: constructive thinking in which different points of view and approaches do not collide, but coexist, a simple and practical way of dividing the thinking process into six different modes, each of which is represented by a metaphorical hat of a certain color.Conclusions. The application of critical thinking technologies: the lotus flower, Edward de Bono's six hats, fishbone, brainstorming, intellectual maps allows to improve the quality of education using the integrative approach of pathophysiology, which will make it possible to effectively implement a competent approach and contribute to the formation of awareness of the practical activity of a doctor.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90658996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ASSOCIATION OF MARKERS OF LOW-GRADE INFLAMMATION IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION WITH TYPE 2 DIABETES MELLITUS: A COMPARATIVE ANALYSIS st段抬高型心肌梗死患者低级别炎症标志物与2型糖尿病的相关性:一项比较分析
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.10
M. Bielinskyi, N. Seredyuk
{"title":"ASSOCIATION OF MARKERS OF LOW-GRADE INFLAMMATION IN PATIENTS WITH ST-ELEVATION MYOCARDIAL INFARCTION WITH TYPE 2 DIABETES MELLITUS: A COMPARATIVE ANALYSIS","authors":"M. Bielinskyi, N. Seredyuk","doi":"10.24061/2413-0737.27.1.105.2023.10","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.10","url":null,"abstract":"Introduction. ST-elevated myocardial infarction (STEMI) remains a significant global health issue and early recognition and management are crucial for reducing damage and improving patient outcomes. Type 2 diabetes mellitus (T2DM), a common metabolic disorder, is linked to STEMI due to factors like insulin resistance, oxidative stress, and low-grade inflammation. Aim. To determine the relationship between T2DM and low-grade inflammation markers in patients with STEMI by comparing the levels of systemic immuneinflammation indices, fibronectin, and soluble sST2 in STEMI patients with and without T2DM.Materials and methods. We enrolled 131 patients diagnosed with STEMI and T2DM who were admitted to the Ivano-Frankivsk Regional Clinical Cardiological Center. The study population was divided into two groups: 1st - consisting of 97 patients with both STEMI and T2DM, and the 2nd - consisting of 34 patients with STEMI only.Results. The Systemic immune‐inflammation index (SII) (2074.50 (1838.45;2331.05) vs 1504.85 (1342.00;1943.38)), Neutrophil‐to‐lymphocyte ratio (NLR) (7.80 (7.10;8.60) vs 6.30 (5.80;8.60), p=0.002), and Aggregate index of systemic inflammation (AISI) (699.45±433.53 vs 531.80±217.27, p=0.033) were significantly higher in patients with STEMI and T2DM compared to patients with STEMI alone. Also, the levels of fibronectin (2.76±0.33 vs 2.53±0.44 ng/mL, p=0.002) and sST2 (23.06±1.19 vs 20.93±1.63 ng/mL, p=0.000) were higher in patients with STEMI and T2DM compared to patients with STEMI alone. The Platelet‐to‐lymphocyte ratio (PLR) (226.01±48.58 vs 224.19±59.61) and Systemic immune-inflammation index (SIRI) (2.59±1.54 vs 2.34±0.98) were not significantly different between the two groups. SII showed a very significant association with the 1st group (OR = 1.004 (1.002-1.005), p<0.001), NLR showed a significant positive association with the 1st group (OR = 1.647, 95% CI = 1.138-2.382, p = 0.008). The other markers showed no significant associations. Fibronectin (OR = 4.524, 95% CI = 1.646-12.430, p = 0.003) and sST2 (OR = 3.594, 95% CI = 2.203-5.864, p < 0.001) were both positively associated with the 1st group. Conclusions. Factors such as age, BMI, and markers of inflammation (SII, sST2, NLR) were significantly linked to T2DM in patients with STEMI. sST2 and SII were found to be better predictors of T2DM compared to other markers of inflammation. These results emphasize the importance of considering multiple factors in evaluating T2DM risk in STEMI patients.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80630535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FEATURES OF TEACHING THE COURSE OF PSYCHIATRY AND NARCOLOGY TO STUDENTS OF HIGHER EDUCATION INSTITUTIONS OF THE MARTIAL STATE 军事院校学生精神病学与麻醉学课程的教学特点
Bukovinian Medical Herald Pub Date : 2023-02-23 DOI: 10.24061/2413-0737.27.1.105.2023.16
O. Yurtsenyuk
{"title":"FEATURES OF TEACHING THE COURSE OF PSYCHIATRY AND NARCOLOGY TO STUDENTS OF HIGHER EDUCATION INSTITUTIONS OF THE MARTIAL STATE","authors":"O. Yurtsenyuk","doi":"10.24061/2413-0737.27.1.105.2023.16","DOIUrl":"https://doi.org/10.24061/2413-0737.27.1.105.2023.16","url":null,"abstract":"Relevance. To form the methodological foundations of teaching the academic discipline \"Psychiatry and Narcology\" in modern wartime conditions. To highlight innovative approaches to effective teaching of the discipline, in particular in the distance learning format.Material and methods. General scientific and specific scientific.Results. The article is devoted to the peculiarities of the teaching methodology of the academic discipline \"Psychiatry and Narcology\" in modern wartime conditions, which helps future doctors to learn the basics of clinical disciplines. It is necessary to master knowledge and skills regarding the diagnosis of the state of mental health of a person, clinical symptoms, prevention of impairment of mental functions in the process of life and various comorbid diseases, conducting medical and psychological examination and rehabilitation of patients. The methodology of conducting practical classes for medical students and using the MOODLE system for effective online learning are highlighted.Conclusions. Taking into account the analysis of information on the teaching of the academic discipline \"Psychiatry and Narcology\" to students of higher education institutions in wartime conditions, we have described the possibilities of using systems for distance learning, in particular the MOODLE system for preparing students of higher education for classes with access to the Internet.","PeriodicalId":9270,"journal":{"name":"Bukovinian Medical Herald","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85963890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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