Brazilian Journal of Psychiatry最新文献_第4页

Body self-image disturbances in women with prolactinoma 催乳素瘤女性的身体自我形象障碍

Brazilian Journal of Psychiatry Pub Date : 2019-07-15 DOI: 10.1590/1516-4446-2018-0325

Helen S Pereira, E. Naliato, A. Moraes, M. Gadelha, L. Vieira Neto, Renan M Almeida, A. Nardi, A. Violante

{"title":"Body self-image disturbances in women with prolactinoma","authors":"Helen S Pereira, E. Naliato, A. Moraes, M. Gadelha, L. Vieira Neto, Renan M Almeida, A. Nardi, A. Violante","doi":"10.1590/1516-4446-2018-0325","DOIUrl":"https://doi.org/10.1590/1516-4446-2018-0325","url":null,"abstract":"Objective: To evaluate body dissatisfaction and distorted body self-image in women with prolactinoma. Methods: Body dissatisfaction and distorted body self-image were evaluated in 80 women with prolactinoma. All patients were in menacme, 34% had normal body mass index (BMI), and 66% were overweight. Most patients (56.2%) had normal prolactin (PRL) levels and no hyperprolactinemia symptoms (52.5%). The Body Shape Questionnaire (BSQ) was used to assess the patients’ dissatisfaction with and concern about their physical form, and the Stunkard Figure Rating Scale (FRS) was used to assess body dissatisfaction and distorted body self-image. The patients were divided according to PRL level (normal vs. elevated) and the presence or absence of prolactinoma symptoms. Results: The normal and elevated PRL groups had similar incidences of body dissatisfaction and distorted body self-image. However, symptomatic patients reported a higher incidence of dissatisfaction than asymptomatic patients. Distorted body self-image was less common among symptomatic patients. Conclusion: Symptomatic patients showed higher body dissatisfaction, but lower body self-image distortion. The presence of symptoms may have been responsible for increased body awareness. The perception of body shape could have triggered feelings of dissatisfaction compared to an ideal lean body. Therefore, a distorted body self-image might not necessarily result in body dissatisfaction in women with prolactinomas.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81412598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Postpartum depression: bipolar or unipolar? Analysis of 434 Polish postpartum women. 产后抑郁：双相抑郁还是单相抑郁？对 434 名波兰产后妇女的分析。

Brazilian Journal of Psychiatry Pub Date : 2017-04-01 Epub Date: 2016-12-08 DOI: 10.1590/1516-4446-2016-1983

Rafał R Jaeschke, Dominika Dudek, Roman Topór-Mądry, Katarzyna Drozdowicz, Wojciech Datka, Marcin Siwek, Janusz Rybakowski

{"title":"Postpartum depression: bipolar or unipolar? Analysis of 434 Polish postpartum women.","authors":"Rafał R Jaeschke, Dominika Dudek, Roman Topór-Mądry, Katarzyna Drozdowicz, Wojciech Datka, Marcin Siwek, Janusz Rybakowski","doi":"10.1590/1516-4446-2016-1983","DOIUrl":"10.1590/1516-4446-2016-1983","url":null,"abstract":"Objective: To assess the prevalence of soft bipolar features in a sample of women with postpartum depressive symptoms, as well as to compare the sociodemographic and obstetric characteristics of subjects with bipolar or unipolar postpartum depressive symptomatology.Methods: Four hundred and thirty-four participants were enrolled in this cross-sectional study. Postpartum depression (PPD) symptoms were assessed using the Edinburgh Postnatal Depression Scale (EPDS), while the Mood Disorder Questionnaire (MDQ) was used to screen for bipolarity features.Results: Of the 434 participants, 66 (15.2%) scored ≥ 13 points on the EPDS, thus fulfilling the screening criteria, and 103 scored ≥ 7 points on the MDQ. In comparison with non-depressed subjects, the women who scored positively on the EPDS were significantly more likely to exhibit symptoms of bipolar spectrum disorders (38 vs. 21%; chi-square test, p = 0.015). Women with bipolar PPD symptomatology were significantly younger than those exhibiting unipolar PPD symptoms (31.0±4.8 years vs. 28.5±4.1 years; t-test, p = 0.03). The groups did not differ in terms of obstetric characteristics.Conclusion: Our findings suggest that patients with PPD symptomatology may be more likely to exhibit soft bipolarity features as compared with non-depressed women.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111438/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88942958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of and factors associated with antipsychotic polypharmacy in patients with serious mental illness: Findings from a cross-sectional study in an upper-middle-income country 严重精神疾病患者抗精神病药物综合用药的患病率及相关因素:来自中高收入国家的横断面研究结果

Brazilian Journal of Psychiatry Pub Date : 2017-02-06 DOI: 10.1590/1516-4446-2016-2015

Kerryn S Armstrong, H. Temmingh

{"title":"Prevalence of and factors associated with antipsychotic polypharmacy in patients with serious mental illness: Findings from a cross-sectional study in an upper-middle-income country","authors":"Kerryn S Armstrong, H. Temmingh","doi":"10.1590/1516-4446-2016-2015","DOIUrl":"https://doi.org/10.1590/1516-4446-2016-2015","url":null,"abstract":"Objective: The aim of our study was to examine the prevalence of and factors associated with antipsychotic polypharmacy (APP) among patients with serious mental illness in the current South African health care context. Methods: We collected data on patient, illness, and treatment characteristics of patients discharged on one or more antipsychotic agents from January to June 2014. We analyzed the associations of APP with demographic and clinical variables using hierarchical multivariable logistic regression, and examined prescription patterns. Results: The prevalence of APP in our study population of 577 patients was 28.4%. Demographic and clinical characteristics significantly associated with APP included age > 29, male sex, diagnosis of schizophrenia, comorbid intellectual disability, comorbid substance use, greater number of hospital admissions, and high-dose prescribing. First-generation antipsychotics and long-acting injectable preparations were prominent in APP combinations. Co-prescription of anticholinergic agents and sodium valproate demonstrated a significant association with APP. Conclusion: APP appears common in our population, despite lack of evidence for the practice and possible risk of harm. Our findings suggest a complex interplay among patient, illness, and treatment factors relevant to APP in our setting that could be targeted for intervention.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76363347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Critical neuropsychobiological analysis of panic attack- and anticipatory anxiety-like behaviors in rodents confronted with snakes in polygonal arenas and complex labyrinths: a comparison to the elevated plus- and T-maze behavioral tests 对啮齿类动物在多边形竞技场和复杂迷宫中面对蛇时的惊恐发作和预期焦虑样行为的关键神经心理生物学分析:与升高的正迷宫和t迷宫行为测试的比较

Brazilian Journal of Psychiatry Pub Date : 2017-02-06 DOI: 10.1590/1516-4446-2015-1895

N. Coimbra, T. Paschoalin-Maurin, G. Bassi, A. Kanashiro, A. Biagioni, T. T. Felippotti, D. H. Elias-Filho, J. Mendes-Gomes, Jade P Cysne-Coimbra, R. C. Almada, B. Lobão-Soares

{"title":"Critical neuropsychobiological analysis of panic attack- and anticipatory anxiety-like behaviors in rodents confronted with snakes in polygonal arenas and complex labyrinths: a comparison to the elevated plus- and T-maze behavioral tests","authors":"N. Coimbra, T. Paschoalin-Maurin, G. Bassi, A. Kanashiro, A. Biagioni, T. T. Felippotti, D. H. Elias-Filho, J. Mendes-Gomes, Jade P Cysne-Coimbra, R. C. Almada, B. Lobão-Soares","doi":"10.1590/1516-4446-2015-1895","DOIUrl":"https://doi.org/10.1590/1516-4446-2015-1895","url":null,"abstract":"Objective: To compare prey and snake paradigms performed in complex environments to the elevated plus-maze (EPM) and T-maze (ETM) tests for the study of panic attack- and anticipatory anxiety-like behaviors in rodents. Methods: PubMed was reviewed in search of articles focusing on the plus maze test, EPM, and ETM, as well as on defensive behaviors displayed by threatened rodents. In addition, the authors’ research with polygonal arenas and complex labyrinth (designed by the first author for confrontation between snakes and small rodents) was examined. Results: The EPM and ETM tests evoke anxiety/fear-related defensive responses that are pharmacologically validated, whereas the confrontation between rodents and snakes in polygonal arenas with or without shelters or in the complex labyrinth offers ethological conditions for studying more complex defensive behaviors and the effects of anxiolytic and panicolytic drugs. Prey vs. predator paradigms also allow discrimination between non-oriented and oriented escape behavior. Conclusions: Both EPM and ETM simple labyrinths are excellent apparatuses for the study of anxiety- and instinctive fear-related responses, respectively. The confrontation between rodents and snakes in polygonal arenas, however, offers a more ethological environment for addressing both unconditioned and conditioned fear-induced behaviors and the effects of anxiolytic and panicolytic drugs.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86200106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 36

The brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism affects memory performance in older adults 脑源性神经营养因子(BDNF)基因Val66Met多态性影响老年人的记忆表现

Brazilian Journal of Psychiatry Pub Date : 2017-01-12 DOI: 10.1590/1516-4446-2016-1980

L. A. de Azeredo, Tatiana de Nardi, M. L. Levandowski, S. Tractenberg, Júlia Kommers-Molina, A. Wieck, T. Q. Irigaray, I. G. da Silva, R. Grassi‐Oliveira

{"title":"The brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism affects memory performance in older adults","authors":"L. A. de Azeredo, Tatiana de Nardi, M. L. Levandowski, S. Tractenberg, Júlia Kommers-Molina, A. Wieck, T. Q. Irigaray, I. G. da Silva, R. Grassi‐Oliveira","doi":"10.1590/1516-4446-2016-1980","DOIUrl":"https://doi.org/10.1590/1516-4446-2016-1980","url":null,"abstract":"Objective: Memory impairment is an important contributor to the reduction in quality of life experienced by older adults, and genetic risk factors seem to contribute to variance in age-related cognitive decline. Brain-derived neurotrophic factor (BDNF) is an important nerve growth factor linked with development and neural plasticity. The Val66Met polymorphism in the BDNF gene has been associated with impaired episodic memory in adults, but whether this functional variant plays a role in cognitive aging remains unclear. The purpose of this study was to investigate the effects of the BDNF Val66Met polymorphism on memory performance in a sample of elderly adults. Methods: Eighty-seven subjects aged > 55 years were recruited using a community-based convenience sampling strategy in Porto Alegre, Brazil. The logical memory subset of the Wechsler Memory Scale-Revised was used to assess immediate verbal recall (IVR), delayed verbal recall (DVR), and memory retention rate. Results: BDNF Met allele carriers had lower DVR scores (p = 0.004) and a decline in memory retention (p = 0.017) when compared to Val/Val homozygotes. However, we found no significant differences in IVR between the two groups (p = 0.088). Conclusion: These results support the hypothesis of the BDNF Val66Met polymorphism as a risk factor associated with cognitive impairment, corroborating previous findings in young and older adults.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74927787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Associations of cerebrovascular metabolism genotypes with neuropsychiatric symptoms and age at onset of Alzheimer’s disease dementia 脑血管代谢基因型与阿尔茨海默病痴呆的神经精神症状和发病年龄的关系

Brazilian Journal of Psychiatry Pub Date : 2017-01-12 DOI: 10.1590/1516-4446-2016-1991

F. F. de Oliveira, E. Chen, Marília Cardoso Smith, P. Bertolucci

{"title":"Associations of cerebrovascular metabolism genotypes with neuropsychiatric symptoms and age at onset of Alzheimer’s disease dementia","authors":"F. F. de Oliveira, E. Chen, Marília Cardoso Smith, P. Bertolucci","doi":"10.1590/1516-4446-2016-1991","DOIUrl":"https://doi.org/10.1590/1516-4446-2016-1991","url":null,"abstract":"Objective: To study associations of cerebrovascular metabolism genotypes and haplotypes with age at Alzheimer’s disease dementia (AD) onset and with neuropsychiatric symptoms according to each dementia stage. Methods: Consecutive outpatients with late-onset AD were assessed for age at dementia onset and Neuropsychiatric Inventory scores according to Clinical Dementia Rating scores, apolipoprotein E gene (APOE) haplotypes, angiotensin-converting enzyme gene (ACE) variants rs1800764 and rs4291, low-density lipoprotein cholesterol receptor gene (LDLR) variants rs11669576 and rs5930, cholesteryl ester transfer protein gene (CETP) variants I422V and TaqIB, and liver X receptor beta gene (NR1H2) polymorphism rs2695121. Results: Considering 201 patients, only APOE-ɛ4 carriers had earlier dementia onset in multiple correlations, as well as less apathy, more delusions, and more aberrant motor behavior. Both ACE polymorphisms were associated with less intense frontally mediated behaviors. Regarding LDLR variants, carriers of the A allele of rs11669576 had less anxiety and more aberrant motor behavior, whereas carriers of the A allele of rs5930 had less delusions, less anxiety, more apathy, and more irritability. CETP variants that included G alleles of I422V and TaqIB were mostly associated with less intense frontally mediated behaviors, while severely impaired carriers of the T allele of rs2695121 had more anxiety and more aberrant motor behavior. Conclusion: Though only APOE haplotypes affected AD onset, cerebrovascular metabolism genotypes were associated with differences in several neuropsychiatric manifestations of AD.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89623031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Elevated plasma concentrations of S100 calcium-binding protein B and tumor necrosis factor alpha in children with autism spectrum disorders 自闭症谱系障碍儿童血浆S100钙结合蛋白B和肿瘤坏死因子α浓度升高

Brazilian Journal of Psychiatry Pub Date : 2017-01-12 DOI: 10.1590/1516-4446-2015-1843

Selin Aktan Guloksuz, O. Abali, E. Cetin, S. Gazioglu, G. Deniz, Abdurrahman Yildirim, I. Kawikova, S. Guloksuz, J. Leckman

{"title":"Elevated plasma concentrations of S100 calcium-binding protein B and tumor necrosis factor alpha in children with autism spectrum disorders","authors":"Selin Aktan Guloksuz, O. Abali, E. Cetin, S. Gazioglu, G. Deniz, Abdurrahman Yildirim, I. Kawikova, S. Guloksuz, J. Leckman","doi":"10.1590/1516-4446-2015-1843","DOIUrl":"https://doi.org/10.1590/1516-4446-2015-1843","url":null,"abstract":"Objective: To investigate plasma concentrations of S100B (a calcium-binding protein derived primarily from the glia) and inflammatory cytokines in children with autism and the relationship between S100B and cytokine concentrations. Methods: Plasma levels of S100B, tumor necrosis factor alpha (TNF-α), interferon gamma, interleukin (IL)-1β, IL-4, IL-6, IL-10, and IL-17A were measured in 40 unmedicated children with autism and 35 normally developing healthy children. The severity of autism was assessed using the Childhood Autism Rating Scale (CARS). Results: Concentrations of both S100B and TNF-α were higher in children with autism before and after adjusting for a priori-selected confounders (age, sex, and body mass index). S100B concentrations were higher in children with severe autism compared to children with mild-moderate autism. However, this association remained as a trend after adjusting for confounders. S100B concentrations correlated positively with TNF-α concentrations. Conclusion: Our findings showing an increase in peripheral concentrations of S100B and TNF-α provide limited support to the hypothesis about the roles of altered immune function and S100B in autism spectrum disorder (ASD). Studies of larger numbers of well-characterized individuals with ASD are needed to clarify the potential role of the immune system in the pathophysiology of this disorder.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77780843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 45

The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data CNR1基因在精神分裂症中的作用:包括未发表数据的系统综述

Brazilian Journal of Psychiatry Pub Date : 2017-01-12 DOI: 10.1590/1516-4446-2016-1969

E. Gouvêa, A. Santos, V. Ota, V. Mrad, A. Gadelha, R. Bressan, Q. Cordeiro, S. Belangero

{"title":"The role of the CNR1 gene in schizophrenia: a systematic review including unpublished data","authors":"E. Gouvêa, A. Santos, V. Ota, V. Mrad, A. Gadelha, R. Bressan, Q. Cordeiro, S. Belangero","doi":"10.1590/1516-4446-2016-1969","DOIUrl":"https://doi.org/10.1590/1516-4446-2016-1969","url":null,"abstract":"Objective: Schizophrenia is a multifactorial disorder. It is known that a combination of extensive multiple common alleles may be involved in its etiology, each contributing with a small to moderate effect, and, possibly, some rare alleles with a much larger effect size. We aimed to perform a systematic review of association studies between schizophrenia (and its subphenotypes) and polymorphisms in the CNR1 gene, which encodes cannabinoid receptors classically implicated in schizophrenia pathophysiology, as well as to present unpublished results of an association study in a Brazilian population. Methods: Two reviewers independently searched for eligible studies and extracted outcome data using a structured form. Papers were retrieved from PubMed and ISI Web of Knowledge using the search term schizophrenia in combination with CNR1 or CB1 or cannabinoid receptor. Twenty-four articles met our inclusion criteria. We additionally present data from a study of our own comparing 182 patients with schizophrenia and 244 healthy controls. Results: No consistent evidence is demonstrated. Conclusion: Some seemingly positive association studies stress the need for further investigations of the possible role of endocannabinoid genetics in schizophrenia.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89857130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Latent class profile of psychiatric symptoms and treatment utilization in a sample of patients with co-occurring disorders 精神症状的潜在类别概况和治疗利用在一个样本的患者共发生的障碍

Brazilian Journal of Psychiatry Pub Date : 2017-01-09 DOI: 10.1590/1516-4446-2016-1972

Luis Villalobos-Gallegos, R. Marín-Navarrete, Calos Roncero, H. González-Cantú

{"title":"Latent class profile of psychiatric symptoms and treatment utilization in a sample of patients with co-occurring disorders","authors":"Luis Villalobos-Gallegos, R. Marín-Navarrete, Calos Roncero, H. González-Cantú","doi":"10.1590/1516-4446-2016-1972","DOIUrl":"https://doi.org/10.1590/1516-4446-2016-1972","url":null,"abstract":"Objective: To identify symptom-based subgroups within a sample of patients with co-occurring disorders (CODs) and to analyze intersubgroup differences in mental health services utilization. Methods: Two hundred and fifteen patients with COD from an addiction clinic completed the Symptom Checklist 90-Revised. Subgroups were determined using latent class profile analysis. Services utilization data were collected from electronic records during a 3-year span. Results: The five-class model obtained the best fit (Bayesian information criteria [BIC] = 3,546.95; adjusted BIC = 3,363.14; bootstrapped likelihood ratio test p < 0.0001). Differences between classes were quantitative, and groups were labeled according to severity: mild (26%), mild-moderate (28.8%), moderate (18.6%), moderate-severe (17.2%), and severe (9.3%). A significant time by class interaction was obtained (chi-square [χ2 [15]] = 30.05, p = 0.012); mild (χ2 [1] = 243.90, p < 0.05), mild-moderate (χ2 [1] = 198.03, p < 0.05), and moderate (χ2 [1] = 526.77, p < 0.05) classes displayed significantly higher treatment utilization. Conclusion: The classes with more symptom severity (moderate-severe and severe) displayed lower utilization of services across time when compared to participants belonging to less severe groups. However, as pairwise differences in treatment utilization between classes were not significant between every subgroup, future studies should determine whether subgroup membership predicts other treatment outcomes.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79007407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Suicide attempts in bipolar I patients: impact of comorbid personality disorders 双相I型患者的自杀企图:共病人格障碍的影响

Brazilian Journal of Psychiatry Pub Date : 2017-01-09 DOI: 10.1590/1516-4446-2016-1982

Severino Bezerra, Amanda Galvão-de-Almeida, Paula Studart, D.F. Martins, André C. Caribé, P. Schwingel, Â. Miranda-Scippa

{"title":"Suicide attempts in bipolar I patients: impact of comorbid personality disorders","authors":"Severino Bezerra, Amanda Galvão-de-Almeida, Paula Studart, D.F. Martins, André C. Caribé, P. Schwingel, Â. Miranda-Scippa","doi":"10.1590/1516-4446-2016-1982","DOIUrl":"https://doi.org/10.1590/1516-4446-2016-1982","url":null,"abstract":"Objective: To evaluate the association between personality disorders (PDs) and suicide attempts (SAs) in euthymic patients with type I bipolar disorder (BD). Methods: One-hundred twenty patients with type I BD, with and without history of SA, were evaluated during euthymia. The assessment included a clinical and sociodemographic questionnaire, the Hamilton Depression Rating Scale, the Young Mania Rating Scale, the Barratt Impulsiveness Scale, and Structured Clinical Interviews for DSM-IV Axis I and II Disorders. Logistic regression was employed to determine associations between history of SA and patient characteristics. Results: History of SA was significantly associated with comorbid axis I disorder, rapid cycling, high impulsivity (attentional, motor, non-planning, and total), having any PD, and cluster B and C PDs. Only cluster B PDs, high attentional impulsivity, and lack of paid occupation remained significant after multivariate analysis. Conclusions: Cluster B PDs were significantly associated with SA in patients with type I BD. High attentional impulsivity and lack of gainful employment were also associated with SA, which suggests that some cluster B clinical and social characteristics may exacerbate suicidal behavior in this population. This finding offers alternatives for new therapeutic interventions.","PeriodicalId":9246,"journal":{"name":"Brazilian Journal of Psychiatry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82195235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9