{"title":"Role of Medical Surveillance in Detecting Baker’s Asthma in Taif city, Saudi Arabia","authors":"Abdullah Alquraishi, Nesriene El Margoushy","doi":"10.15761/gdt.1000169","DOIUrl":"https://doi.org/10.15761/gdt.1000169","url":null,"abstract":"","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67463688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Odabasoglu, O. Yildirim, Z. Halıcı, H. Aygun, M. Halici, Fadime Atalay, E. Çadırcı, I. Can, A. Cakir, Ozlem Aydin Berktas, A. Aslan, Y. Bayir, F. Erdoğan, B. Aksakal
{"title":"The effect of usnic acid supplementation on rabbit’s tissues surrounding implant apoptosis and some enzyme activities","authors":"F. Odabasoglu, O. Yildirim, Z. Halıcı, H. Aygun, M. Halici, Fadime Atalay, E. Çadırcı, I. Can, A. Cakir, Ozlem Aydin Berktas, A. Aslan, Y. Bayir, F. Erdoğan, B. Aksakal","doi":"10.15761/gdt.1000168","DOIUrl":"https://doi.org/10.15761/gdt.1000168","url":null,"abstract":"Usnea longissima Ach ., is a type of lichen known for its protective effects. In this study, we examined the effects of olive oil and usnic acid against apoptosis in rabbit femurs after titanium implantation. We determined that lichen metabolite and olive oil activate caspase-dependent programmatic cell death unlike necrosis. Both orally and locally administered olive oil and usnic acid showed proapoptotic effect through the activation of caspase 2, 3, 8 and 9. Also, they showed strong myeloperoxidase (MPO) and inducible nitric oxide synthase (iNOS) activities. However, iNOS and MPO activities do not have a strong effect in local application. decreased SOD activity and GSH level. In parallel, titanium implantation in these tissues also decreased. In the light of the data obtained, both usnic acid and olive oil induced apoptotic cell death. Therefore, it can be used as a proapoptotic agent in the treatment of various diseases.","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67463936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Tsabang, Lwd Tsambang, C G Yedjou, Paul B Tchounwou
{"title":"Socio-cultural contribution to medicinal plants assessment and sustainable development: case of antidiabetic and antihypertensive plants in Cameroon.","authors":"N Tsabang, Lwd Tsambang, C G Yedjou, Paul B Tchounwou","doi":"10.15761/GDT.1000112","DOIUrl":"10.15761/GDT.1000112","url":null,"abstract":"<p><p>Diabetes and hypertension rank among human diseases that are very difficult to control. The medicinal material of Cameroon can provide much information on ethnic folklore practices and traditional aspects of therapeutically important natural products. Cameroon has a very rich cultural diversity with different traditional systems of medicine that need more evidence-based studies on both crude extracts and purified phytomolecules. Therefore, an ethnobotanical study was conducted on 58 socio-cultural population groups living in different phytogeographic units of Cameroon in order to collect various medicinal plants or recipes. A two by two comparison of social-cultural groups of the same phytogeographic unit indicated a significant difference in 86.97% of medicinal plants or recipes comparisons' cases. A total of two hundred and eight recipes were identified, among which 75 were used for diabetes and hypertension treatment, 74 for hypertension alone, and 59 for diabetes alone. Also, two hundred and three plants were identified among which 33 were cultivated and marketed by 25 farming families engaged in integrated agriculture and selling of antidiabetic and antihypertensive plants to enhance their socio-economic status.</p>","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36220522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}