Global drugs and therapeutics最新文献

Involvement of Pharmacy Students in a Campaign on Rational Drug Use: A Brazilian Experience of Active Learning 药学学生参与合理用药运动:巴西主动学习的经验

Global drugs and therapeutics Pub Date : 2022-02-02 DOI: 10.31487/j.gdt.2021.01.02

R. Contri, I. Petry, J. Emanuelli, IC Kulkamp Guerreiro

{"title":"Involvement of Pharmacy Students in a Campaign on Rational Drug Use: A Brazilian Experience of Active Learning","authors":"R. Contri, I. Petry, J. Emanuelli, IC Kulkamp Guerreiro","doi":"10.31487/j.gdt.2021.01.02","DOIUrl":"https://doi.org/10.31487/j.gdt.2021.01.02","url":null,"abstract":"The rational drug use refers to the correct use of the correct medication, which is obtained from a trustable source and with health assistance. The aim of this study was to describe an experience of active learning by the construction of a public campaign on rational drug use that involved undergraduate pharmacy students and to evaluate the students’ satisfaction and perceptions. The activity started with the creation of an educational flyer using a collaborative online platform. Then, a dramatization session took place before the students’ participation in a public outreach campaign on rational drug use. Written feedback from the students, collected by an open question, evaluated their satisfaction and general perceptions regarding the activities. After evaluating clinical cases, raising key-points on the acquisition, administration, storage and disposal of drugs, creating the flyer and performing a training session, the campaign on rational drug use was successfully performed. Most of the students (96.67%) were satisfied with the active learning activities. The students reported being more aware of their role in their collective learning as well as having their communication, critical thinking and writing skills improved. The campaign itself and the related activities showed the importance of active learning methodologies in pharmacy education.","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44595382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19 Vaccine Acceptance by Patients Attending a Primary Health Care Facility in Durban 德班初级卫生保健机构患者接受COVID-19疫苗的情况

Global drugs and therapeutics Pub Date : 2021-02-11 DOI: 10.31487/J.GDT.2021.01.01

A. Hoque, S. Buckus, M. Hoque, A. M. U. Alam, Nisha Singh, M. Hoque

{"title":"COVID-19 Vaccine Acceptance by Patients Attending a Primary Health Care Facility in Durban","authors":"A. Hoque, S. Buckus, M. Hoque, A. M. U. Alam, Nisha Singh, M. Hoque","doi":"10.31487/J.GDT.2021.01.01","DOIUrl":"https://doi.org/10.31487/J.GDT.2021.01.01","url":null,"abstract":"Introduction: There is no specific treatment and vaccine for COVID-19 yet. The prospective vaccine is the\u0000primary prevention and is the promising preventive strategy to gain herd immunity. The study aimed to\u0000identify COVID-19 vaccine acceptance rate among primary health care attendees at Durban, South Africa.\u0000Method: A questionnaire based cross-sectional study was conducted at the Kwadabeka Community Health\u0000Centre, Durban, South Africa. Chi-square test and logistic regression were carried out to identify the factors\u0000for COVID-19 vaccine acceptability. P-values <0.05 were reported and considered statistically significant.\u0000Results: Almost two-thirds (61.4%) of the participants reported that they would accept a COVID-19\u0000vaccine. Logistic regression analysis found that respondents’ attitude on whether “COVID-19 pandemic\u0000will be dealt with successfully” was 2.3 times more likely to accept the vaccine (OR=2.3, 95% CI: 1.3-3.8,\u0000p<0.05) and good practice on “use of a face mask to public places were 3 times more likely to accept the\u0000vaccine (OR=3.0, 95% CI: 1.5-6.1, P<0.05). On the contrary, knowledge on “only elderly people die from\u0000COVID-19 (False)” revealed that 44% were less likely to accept the vaccine (OR=0.56, 95% CI: 0.33-0.95,\u0000P<0.05) and practice on social distance “keep a distance of 1-2 m in public places” was 69% less likely to\u0000accept the vaccine (OR=0.31, 95% CI: 0.15-0.63, p<0.05).\u0000Conclusion: The COVID-19 vaccine acceptance rate is comparable with other studies. However,\u0000community-based studies and a mass educational and communication campaign to promote the COVID-19\u0000vaccination coverage to the general population are recommended.","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44011956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemical Composition and Evaluation of the Antimicrobial Activity of the Of Illicium Verum and the Derivations of Protocatechuic Acid 八角及其原儿茶酸衍生物的化学成分及抗菌活性评价

Global drugs and therapeutics Pub Date : 2020-03-18 DOI: 10.31487/j.gdt.2020.01.03

Huma Bhatti, Aqeel Ahmad, Fraha Naz Chohan, Sara, S. Faizi

引用次数: 0

More possibilities from Rivastigmine to new potential agents on treating Alzheimer's disease: In silico study 从利瓦斯汀到治疗阿尔茨海默病的新潜在药物的更多可能性:计算机研究

Global drugs and therapeutics Pub Date : 2019-01-01 DOI: 10.15761/gdt.1000164

Zhi-Gang Sun, Qing Yuan, Yushun Yang

{"title":"More possibilities from Rivastigmine to new potential agents on treating Alzheimer's disease: In silico study","authors":"Zhi-Gang Sun, Qing Yuan, Yushun Yang","doi":"10.15761/gdt.1000164","DOIUrl":"https://doi.org/10.15761/gdt.1000164","url":null,"abstract":"Along with the development of the modern world, advanced medicinal and therapeutic conditions have encouraged longevity to be the common sense [1]. Concomitantly, the usual defined diseases for elder population, have forced the researchers to face the fact that they are occurring with higher percentages and stretching their claws to younger people [2,3]. Among them, Alzheimer’s disease (AD) is of course one of the most hazardous and frequent, which ruined the capabilities of remembering recent things, organizing language, distinguishing orientations and controlling mood [4,5]. AD is a widely known chronic neurodegenerative disease and it caused a majority of dementia cases (over 60%) [6,7]. On the contrary, the cause of AD is still poorly revealed. Since the major phenomena are amyloid beta (Aβ) deposits, tau protein abnormalities and neuronal death, several hypotheses have been raised accordingly [8-10]: 1) Genetic cause, mainly the mutations in genes encoding amyloid precursor protein (APP) and presenilins 1 and 2 [11]; 2) Cholinergic hypothesis, the most typical one with the most currently available drugs based [12-14]; 3) Amyloid hypothesis, the currently leading opinion in this field but the two developed vaccines Bapineuzumab and Solanezumab both failed the Phase III clinical trials [15-18]; 4) Tau hypothesis, the most accepted target following the amyloid with potential agents on the promotion of Tau’s decomposition and the inhibition of its accumulation or phosphorylation [19-21]; 5) Other hypotheses including inflammation, aluminium, smoking and gum diseases [22-25]. In spite of the antiamyloid vaccine’s failures, the very recent study also questioned the rationality of inhibition Tau because its multiple functions [26]. Thus, acetylcholinesterase inhibitors (AChEI) are still the down-to-earth choices of the patients of AD.","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67464064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HIV/AIDS prevalence cases among patient undergoing follow-up in federal teaching hospital Gombe state Nigeria application of multivariate analysis 尼日利亚贡贝州联邦教学医院接受随访的患者艾滋病毒/艾滋病流行情况应用多变量分析

Global drugs and therapeutics Pub Date : 2019-01-01 DOI: 10.15761/gdt.1000166

I. Etikan, K. Bala, O. Tosun, S. Sanisoğlu, Meliz Yuvalı

{"title":"HIV/AIDS prevalence cases among patient undergoing follow-up in federal teaching hospital Gombe state Nigeria application of multivariate analysis","authors":"I. Etikan, K. Bala, O. Tosun, S. Sanisoğlu, Meliz Yuvalı","doi":"10.15761/gdt.1000166","DOIUrl":"https://doi.org/10.15761/gdt.1000166","url":null,"abstract":"The researcher in this write-up employed the use of multivariate statistical methods to find a more proactive solution to reduce and if possible to stop the rate of death as a result HIV/AIDS, so that with time it will be a history for patient leaving with HIV/AIDS in Teaching Hospital Gombe State and Nigeria in general. The powerful statistical softwares used in accessing the outcomes of this research is SPSS. This software helps the researcher in revealing those patients that were involved in relocating to other places, losing to follow up and those with incomplete attendance. 5000 sample of HIV/AIDS patient were randomly selected from the Hospital on antiretroviral therapy database to achieve this purpose. However from the sane investigation the end result revealed that there was significant difference between people living with the virus and people dying because of the virus. While the case of turnout from the record and during the follow-up, showed a higher percentage of people leading with virus comes from females, married people and younger age after taking statistics. However, several individuals from different region dying with the virus, is as a result of negative belief about the virus and obstruction of rules and regulation of taking drugs. This upsetting problem encouraged the researcher to recommend to the Government and Non-Governmental body to take immediate action in tackling this issue, so that it should be be-young reduction, but to stop the feature coming up generation with contamination of the virus.","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67463726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An efficient technique for testing topical antifungal drugs for treating nail infections 一种有效的测试治疗指甲感染的局部抗真菌药物的技术

Global drugs and therapeutics Pub Date : 2019-01-01 DOI: 10.15761/gdt.1000165

H. Yoell, Lijun Liu, W. Lougheed, Christopher F Evans, Jianping Xu

{"title":"An efficient technique for testing topical antifungal drugs for treating nail infections","authors":"H. Yoell, Lijun Liu, W. Lougheed, Christopher F Evans, Jianping Xu","doi":"10.15761/gdt.1000165","DOIUrl":"https://doi.org/10.15761/gdt.1000165","url":null,"abstract":"Nail infection (onychomycosis) affects people worldwide, with estimated prevalence of about 14% in North America [1], 20% in East Asia [2], and 23% [3] in Europe. Among these, about 50% are caused by fungal pathogens [4]. Epidemiological surveys have identified several risk factors for onychomycosis, including old age; compromised immunity from HIV infection, organ transplantation, and cancer treatments; wearing non-breathable tight footwear for extended periods of time; working in certain occupations such as mining, lodging, and the military; extended use of damp spaces such as locker rooms and gymnasiums that are shared by large groups of people; and physical activities such as long-distance running and playing racket sports that cause trauma to nails [4-7]. With an increasing number of people exposed to these risk factors, the prevalence of onychomycosis is expected to rise, especially in developed countries with a looming aging population. While typically not life-threatening and often dismissed as merely an unsightly nuisance, onychomycosis can cause noticeable disfigurement of the nail, discomfort, and pain, and impact mobility and occupation choices [4,8]. In severe cases, onychomycosis can lead to systemic infection, limb amputation, and even death. However, none of the current treatments are ideal and often require extended long-term therapy and/or have significant side effects, especially for oral medications [5,8]. As a result, there is a pressing need to develop effective, topical treatment strategies.","PeriodicalId":92367,"journal":{"name":"Global drugs and therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67463903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Assessment of Knowledge and Attitude toward Antibiotic Use and Resistance among Students of International University of Africa, Medical complex, Sudan 苏丹非洲国际大学医学院学生抗生素使用及耐药性知识与态度评估

Global drugs and therapeutics Pub Date : 2019-01-01 DOI: 10.15761/gdt.1000171

Lawan Sa’adatu Sunusi, Mousnad Mohamed Awad, N. M. Hassan, Chiroma Abubakar Isa

引用次数: 12

Menstrual hygiene management: A study of adolescent schoolgirls in sebeta town, oromia region, Ethiopia 经期卫生管理:埃塞俄比亚奥罗米亚地区sebeta镇青春期女学生的研究

Global drugs and therapeutics Pub Date : 2019-01-01 DOI: 10.15761/gdt.1000175

Abera Degefu Birhane, Mirgissa Kaba Serbessa, T. T. Degfie

引用次数: 10

Comparative Study of Tympanoplasty Using Temporalis Fascia and Cartilage at Al Hada Hospital, Taif, Saudi Arabia 沙特阿拉伯塔伊夫Al Hada医院颞筋膜与软骨鼓室成形术的比较研究

Global drugs and therapeutics Pub Date : 2019-01-01 DOI: 10.15761/gdt.1000167

Sara Hamed Abudarak, Sultanah Naser Alshreef, Sulaiman Awadh Althobaiti, Ayeshah Beeshi Alqarni